Search Results - Michael W. Wilson

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  1. 1
    Property-based design of a glucosylceramide synthase inhibitor that reduces glucosylceramide in the brain

    Property-based design of a glucosylceramide synthase inhibitor that reduces glucosylceramide in the brain by Scott D. Larsen, Michael W. Wilson, Akira Abe, Liming Shu, Christopher H. George, Paul D. Kirchhoff, Hollis D. Showalter, Jianming Xiang, Richard F. Keep, James A. Shayman

    Published 2011
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  2. 2
    X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

    X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases by Yahira M. Báez-Santos, Scott J. Barraza, Michael W. Wilson, Michael P. Agius, Anna M. Mielech, Nicole D. Armstrong, Susan C. Baker, Scott D. Larsen, Andrew D. Mesecar

    Published 2014
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  3. 3
    Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine

    Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine by Helen V. Waldschmidt, Kristoff T. Homan, M.C. Cato, Osvaldo Cruz-Rodríguez, Alessandro Cannavò, Michael W. Wilson, Jianliang Song, Joseph Y. Cheung, Walter J. Koch, J.J.G. Tesmer, Scott D. Larsen

    Published 2017
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  4. 4
    Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma

    Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma by Kim M. Hutchings, Erika M. Lisabeth, Walajapet G. Rajeswaran, Michael W. Wilson, Roderick J. Sorenson, Phillip L. Campbell, Jeffrey H. Ruth, Asif Amin, Pei‐Suen Tsou, Jeffrey R. Leipprandt, Samuel R. Olson, Bo Wen, Ting Zhao, Duxin Sun, Dinesh Khanna, David A. Fox, Richard R. Neubig, Scott D. Larsen

    Published 2017
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  5. 5
    A harmonized public resource of deeply sequenced diverse human genomes

    A harmonized public resource of deeply sequenced diverse human genomes by Zan Koenig, Mary T. Yohannes, Lethukuthula L. Nkambule, Xuefang Zhao, Julia K. Goodrich, Heesu Ally Kim, Michael W. Wilson, Grace Tiao, Stephanie P. Hao, Nareh Sahakian, Katherine R. Chao, Mark Walker, Yunfei Lyu, Heidi L. Rehm, Benjamin M. Neale, Michael E. Talkowski, Mark J. Daly, Harrison Brand, Konrad J. Karczewski, Elizabeth G. Atkinson, Alicia R. Martin

    Published 2023
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  6. 6
    A harmonized public resource of deeply sequenced diverse human genomes

    A harmonized public resource of deeply sequenced diverse human genomes by Zan Koenig, Mary T. Yohannes, Lethukuthula L. Nkambule, Xuefang Zhao, Julia K. Goodrich, Heesu Ally Kim, Michael W. Wilson, Grace Tiao, Stephanie P. Hao, Nareh Sahakian, Katherine R. Chao, Mark A. Walker, Yunfei Lyu, Heidi L. Rehm, Benjamin M. Neale, Michael E. Talkowski, Mark J. Daly, Harrison Brand, Konrad J. Karczewski, Elizabeth G. Atkinson, Alicia R. Martin

    Published 2024
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  7. 7
    <i>seqr</i> : A web‐based analysis and collaboration tool for rare disease genomics

    <i>seqr</i> : A web‐based analysis and collaboration tool for rare disease genomics by Lynn Pais, Hana Snow, Ben Weisburd, Shifa Zhang, Samantha Baxter, Stephanie DiTroia, Emily O’Heir, Eleina England, Katherine R. Chao, Gabrielle Lemire, Ikeoluwa Osei‐Owusu, Grace E. VanNoy, Michael W. Wilson, Kevin Nguyen, Harindra Arachchi, William Phu, Matthew Solomonson, Stacy Mano, Melanie O’Leary, Alysia Kern Lovgren, Lawrence Babb, Christina Austin‐Tse, Heidi L. Rehm, Daniel G. MacArthur, Anne O’Donnell‐Luria

    Published 2022
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  8. 8
    A genome-wide mutational constraint map quantified from variation in 76,156 human genomes

    A genome-wide mutational constraint map quantified from variation in 76,156 human genomes by Siwei Chen, Laurent C. Francioli, Julia K. Goodrich, Ryan L. Collins, Masahiro Kanai, Qingbo Wang, Jessica Alföldi, Nicholas A. Watts, Christopher Vittal, Laura D. Gauthier, Timothy Poterba, Michael W. Wilson, Yekaterina Tarasova, William Phu, Mary T. Yohannes, Zan Koenig, Yossi Farjoun, Eric Banks, Stacey Donnelly, Stacey Gabriel, Namrata Gupta, Steven Ferriera, Charlotte Tolonen, Sam Novod, Louis Bergelson, David Roazen, Valentín Ruano-Rubio, Miguel Covarrubias, Christopher Llanwarne, Nikelle Petrillo, Gordon Wade, Thibault Jeandet, Ruchi Munshi, Kathleen Tibbetts, Anne O’Donnell‐Luria, Matthew Solomonson, Cotton Seed, Alicia R. Martin, Michael E. Talkowski, Heidi L. Rehm, Mark J. Daly, Grace Tiao, Benjamin M. Neale, Daniel G. MacArthur, Konrad J. Karczewski

    Published 2022
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  9. 9
    Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract

    Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract by Amelie T. van der Ven, Dervla M. Connaughton, Hadas Ityel, Nina Mann, Makiko Nakayama, Jing Chen, Asaf Vivante, Daw‐Yang Hwang, Julian Schulz, Daniela A. Braun, Johanna Magdalena Schmidt, David Schapiro, Ronen Schneider, Jillian K. Warejko, Ankana Daga, Amar J. Majmundar, Weizhen Tan, Tilman Jobst‐Schwan, Tobias Hermle, Eugen Widmeier, Shazia Ashraf, Ali Amar, Charlotte A. Hoogstraaten, Hannah Hugo, Thomas M. Kitzler, Franziska Kause, Caroline M. Kolvenbach, Rufeng Dai, Leslie Spaneas, Kassaundra Amann, Deborah R. Stein, Michelle A. Baum, Michael J.G. Somers, Nancy Rodig, Michael A. Ferguson, Avram Z. Traum, Ghaleb H. Daouk, Radovan Bogdanović, Nataša Stajić, Neveen A. Soliman, Jameela A. Kari, Sherif El Desoky, Hanan Fathy, Danko Milošević, Muna Al‐Saffar, Hazem S. Awad, Loai Eid, Aravind Selvin, Prabha Senguttuvan, Simone Sanna‐Cherchi, Heidi L. Rehm, Daniel G. MacArthur, Monkol Lek, Kristen M. Laricchia, Michael W. Wilson, Shrikant Mane, Richard P. Lifton, Richard S. Lee, Stuart B. Bauer, Lu W, Heiko Reutter, Velibor Tasić, Shirlee Shril, Friedhelm Hildebrandt

    Published 2018
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  10. 10
    Critical assessment of variant prioritization methods for rare disease diagnosis within the rare genomes project

    Critical assessment of variant prioritization methods for rare disease diagnosis within the rare genomes project by Sarah L. Stenton, Melanie O’Leary, Gabrielle Lemire, Grace E. VanNoy, Stephanie DiTroia, Vijay Ganesh, Emily Groopman, Emily O’Heir, Brian Mangilog, Ikeoluwa Osei‐Owusu, Lynn Pais, Jillian Serrano, Moriel Singer‐Berk, Ben Weisburd, Michael W. Wilson, Christina Austin‐Tse, Marwa Abdelhakim, Azza Althagafi, Giulia Babbi, Riccardo Bellazzi, Samuele Bovo, Maria Giulia Carta, Rita Casadio, Pieter-Jan Coenen, Federica De Paoli, Matteo Floris, Manavalan Gajapathy, Robert Hoehndorf, Julius O.B. Jacobsen, Thomas Joseph, Akash Kamandula, Panagiotis Katsonis, Cyrielle Kint, Olivier Lichtarge, Ivan Limongelli, Yulan Lu, Paolo Magni, Tarun Karthik Kumar Mamidi, Pier Luigi Martelli, M. Mulargia, Giovanna Nicora, Keith Nykamp, Vikas Pejaver, Yisu Peng, Thi Hong Cam Pham, Maurizio Podda, Aditya Rao, Ettore Rizzo, Vangala G. Saipradeep, Castrense Savojardo, Peter Schols, Yang Shen, Naveen Sivadasan, Damian Smedley, Dorian Soru, Rajgopal Srinivasan, Yuanfei Sun, Uma Sunderam, Wuwei Tan, Naina Tiwari, Xiao Wang, Yaqiong Wang, Amanda M. Williams, Elizabeth A. Worthey, Rujie Yin, Yuning You, Daniel Zeiberg, Susanna Zucca, Constantina Bakolitsa, Steven E. Brenner, Stephanie M. Fullerton, Predrag Radivojac, Heidi L. Rehm, Anne O’Donnell‐Luria

    Published 2024
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  11. 11
    Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes

    Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes by Siwei Chen, Laurent C. Francioli, Julia K. Goodrich, Ryan L. Collins, Masahiro Kanai, Qingbo Wang, Jessica Alföldi, Nicholas A. Watts, Christopher Vittal, Laura D. Gauthier, Timothy Poterba, Michael W. Wilson, Yekaterina Tarasova, William Phu, Riley Grant, Mary T. Yohannes, Zan Koenig, Yossi Farjoun, Eric Banks, Stacey Donnelly, Stacey Gabriel, Namrata Gupta, Steven Ferriera, Charlotte Tolonen, Sam Novod, Louis Bergelson, David Roazen, Valentín Ruano-Rubio, Miguel Covarrubias, Christopher Llanwarne, Nikelle Petrillo, Gordon Wade, Thibault Jeandet, Ruchi Munshi, Kathleen Tibbetts, María T. Abreu, Carlos A. Aguilar‐Salinas, Tariq Ahmad, Christine M. Albert, Diego Ardissino, Irina M. Armean, Elizabeth G. Atkinson, Gil Atzmon, John Barnard, Samantha Baxter, Laurent Beaugerie, Emelia J. Benjamin, David Benjamin, Michael Boehnke, Lori L. Bonnycastle, Erwin P. Böttinger, Donald W. Bowden, Matthew J. Bown, Harrison Brand, Steven R. Brant, Ted Brookings, Sam Bryant, Sarah E. Calvo, Hannia Campos, John C. Chambers, Juliana C.N. Chan, Katherine R. Chao, Sinéad B. Chapman, Daniel I. Chasman, Rex L. Chisholm, Judy H. Cho, Rajiv Chowdhury, Mina K. Chung, Wendy K. Chung, Kristian Cibulskis, Bruce M. Cohen, Kristen M. Connolly, Adolfo Correa, Beryl B. Cummings, Dana Dabelea, John Danesh, Dawood Darbar, Phil Darnowsky, Joshua C. Denny, Ravindranath Duggirala, Josée Dupuis, Patrick T. Ellinor, Roberto Elosúa, James Emery, Eleina England, Jeanette Erdmann, Tõnu Esko, Emily Evangelista, Diane Fatkin, José C. Florez, André Franke, Jack Fu, Martti Färkkilâ, Kiran Garimella, Jeff Gentry, Gad Getz, David C. Glahn, Benjamin Gläser, Stephen J. Glatt, David B. Goldstein

    Published 2024
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  12. 12
    Genomic autopsy to identify underlying causes of pregnancy loss and perinatal death

    Genomic autopsy to identify underlying causes of pregnancy loss and perinatal death by Alicia B. Byrne, Peer Arts, Thuong Ha, Karin S. Kassahn, Lynn Pais, Anne O’Donnell‐Luria, François Aguet, Harindra Arachchi, Christina Austin‐Tse, Lawrence Babb, Samantha Baxter, Harrison Brand, Jaime Chang, Katherine R. Chao, Ryan L. Collins, Beryl B. Cummings, Kayla Delano, Stephanie DiTroia, Eleina England, Emily Evangelista, Selin Everett, Laurent C. Francioli, Jack B. Fu, Vijay Ganesh, Kiran Garimella, Laura D. Gauthier, Julia K. Goodrich, Sanna Gudmundsson, Stacey J. Hall, Yongqing Huang, Steve Jahl, Kristen M. Laricchia, Kathryn E. Larkin, Monkol Lek, Gabrielle Lemire, Rachel B. Lipson, Alysia Kern Lovgren, Daniel G. MacArthur, Brian Mangilog, Stacy Mano, Jamie L. Marshall, Thomas E. Mullen, Kevin Nguyen, Emily O’Heir, Melanie O’Leary, Ikeoluwa Osei‐Owusu, Jorge Perez de Acha Chavez, Emma Pierce‐Hoffman, Heidi L. Rehm, Jillian Serrano, Moriel Singer‐Berk, Hana Snow, Matthew Solomonson, Rachel G. Son, Abigail Sveden, Michael E. Talkowski, Grace Tiao, Miriam S. Udler, Zaheer M. Valivullah, Elise Valkanas, Grace E. VanNoy, Qingbo Wang, Nicholas A. Watts, Ben Weisburd, Clara E. Williamson, Michael W. Wilson, Lauren Witzgall, Monica H. Wojcik, Isaac Wong, Jordan C. Wood, Shifa Zhang, Milena Babic, Mahalia S. B. Frank, Jinghua Feng, Paul Wang, David Lawrence, Leila Eshraghi, Luis Arriola, John Toubia, Van Hung Nguyen, Disna Abeysuriya, Lesley C. Adès, David J. Amor, Susan Arbuckle, Madhura Bakshi, Bligh Berry, Tiffany Boughtwood, Adam Bournazos, Alessandra Bray, Fiona Chan, Yuen Chan, Clara W. T. Chung, Jonathan R. Clark, Jackie Collett, Alison Colley, Felicity Collins, Sandra T. Cooper, Mark Corbett, Jane E. Dahlstrom, Peter A. Dargaville

    Published 2023
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  13. 13
    Expanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders

    Expanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders by Julie A. Jurgens, Brenda J. Barry, Wai‐Man Chan, Sarah MacKinnon, Mary C. Whitman, Paola M. Matos Ruiz, Brandon M. Pratt, Eleina England, Lynn Pais, Gabrielle Lemire, Emily Groopman, Carmen Glaze, Kathryn A. Russell, Moriel Singer‐Berk, Silvio Alessandro Di Gioia, Arthur S. Lee, Caroline Andrews, Sherin Shaaban, Megan M. Wirth, Sarah Bekele, Melissa Toffoloni, Victoria R. Bradford, Emma E. Foster, Lindsay Berube, Cristina Rivera-Quiles, Fiona M. Mensching, Alba Sanchis-Juan, Jack Fu, Isaac Wong, Xuefang Zhao, Michael W. Wilson, Ben Weisburd, Monkol Lek, Hugo Hernán Abarca-Barriga, Christiane Al‐Haddad, Jeffrey Berman, Erick D. Bothun, Jenina Capasso, Oscar F. Chacón‐Camacho, Lan Chang, Stephen P. Christiansen, Maria Laura Ciccarelli, Monique Cordonnier, Gerald F. Cox, Cynthia J. Curry, Linda R. Dagi, Thomas Lee Dahm, Karen L. David, Bradley V. Davitt, Teresa de Berardinis, Joseph L. Demer, Julie Désir, Fabiana D’Esposito, Arlene V. Drack, Eric Eggenberger, James E. Elder, Alexandra T. Elliott, K. David Epley, Hagit Baris Feldman, Carlos R. Ferreira, Maree Flaherty, Anne B. Fulton, Christina Gerth‐Kahlert, Irène Gottlob, Stephen Grill, Dorothy Halliday, Frank Hanisch, Eleanor Hay, Gena Heidary, C. L. Holder, Jonathan C. Horton, Alessandro Iannaccone, Sherwin J. Isenberg, Suzanne C. Johnston, Alon Kahana, James A. Katowitz, Melanie Kazlas, Natalie C. Kerr, Virginia Kimonis, Melissa W. Ko, Feray Koc, Dorte Ancher Larsen, Guillermo Lay‐Son, Danielle Ledoux, Alex V. Levin, Ronald Levy, Christopher J. Lyons, David A. Mackey, Adriano Magli, Iason S. Mantagos, Candice Marti, Isabelle Maystadt, Fiona McKenzie, Manoj P. Menezes, Claudia N. Mikail, David T. Miller, Kathryn B. Miller, Monte D. Mills, Kaori Miyana, Hans Ulrik Møller

    Published 2024
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