Výsledky vyhledávání - Michael Sigouros

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  1. 1
    Immunogenomic Landscape of Neuroendocrine Prostate Cancer

    Immunogenomic Landscape of Neuroendocrine Prostate Cancer Autor Bhavneet Bhinder, Alison Ferguson, Michael Sigouros, Manik Uppal, Ahmed G. Elsaeed, Rohan Bareja, Hussein Alnajar, Kenneth Wha Eng, Vincenza Conteduca, Andrea Sboner, Juan Miguel Mosquera, Olivier Elemento, Himisha Beltran

    Vydáno 2023
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  2. 2
    Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer

    Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer Autor Ritika Tiwari, Nishat Manzar, Vipul Bhatia, Anjali Yadav, Mushtaq Ahmad Nengroo, Dipak Datta, Shannon Carskadon, Nilesh Gupta, Michael Sigouros, Francesca Khani, Matti Poutanen, Amina Zoubeidi, Himisha Beltran, Nallasivam Palanisamy, Bushra Ateeq

    Vydáno 2020
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  3. 3
    Clinical features of neuroendocrine prostate cancer

    Clinical features of neuroendocrine prostate cancer Autor Vincenza Conteduca, Clara Oromendia, Kenneth Eng, Rohan Bareja, Michael Sigouros, Ana M. Molina, Bishoy M. Faltas, Andrea Sboner, Juan Miguel Mosquera, Olivier Elemento, David M. Nanus, Scott T. Tagawa, Karla V. Ballman, Himisha Beltran

    Vydáno 2019
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  4. 4
    SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy

    SLFN11 Expression in Advanced Prostate Cancer and Response to Platinum-based Chemotherapy Autor Vincenza Conteduca, Sheng‐Yu Ku, Loredana Puca, Megan Slade, Luisa Fernandez, Judy Hess, Rohan Bareja, Panagiotis J. Vlachostergios, Michael Sigouros, Juan Miguel Mosquera, Andrea Sboner, David M. Nanus, Olivier Elemento, Ryan Dittamore, Scott T. Tagawa, Himisha Beltran

    Vydáno 2020
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  5. 5
    Impact of Therapy on Genomics and Transcriptomics in High-Risk Prostate Cancer Treated with Neoadjuvant Docetaxel and Androgen Deprivation Therapy

    Impact of Therapy on Genomics and Transcriptomics in High-Risk Prostate Cancer Treated with Neoadjuvant Docetaxel and Androgen Deprivation Therapy Autor Himisha Beltran, Alexander W. Wyatt, Edmund C.P. Chedgy, Adam Donoghue, Matti Annala, Evan W. Warner, Kevin Beja, Michael Sigouros, Fan Mo, Ladan Fazli, Colin C. Collins, James A. Eastham, Michael J. Morris, Mary‐Ellen Taplin, Andrea Sboner, Susan Halabi, Martin Gleave

    Vydáno 2017
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  6. 6
    Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer

    Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer Autor Himisha Beltran, Alessandro Romanel, Vincenza Conteduca, Nicola Casiraghi, Michael Sigouros, Gian Marco Franceschini, Francesco Orlando, Tarcisio Fedrizzi, Sheng‐Yu Ku, Emma Dann, Alicia Alonso, Juan Miguel Mosquera, Andrea Sboner, Jenny Xiang, Olivier Elemento, David M. Nanus, Scott T. Tagawa, Matteo Benelli, Francesca Demichelis

    Vydáno 2020
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  7. 7
    Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer

    Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer Autor Nicholas J. Brady, Alyssa Bagadion, Richa Singh, Vincenza Conteduca, Lucie Van Emmenis, Elisa Arceci, Hubert Pakula, Ryan Carelli, Francesca Khani, Martin Bakht, Michael Sigouros, Rohan Bareja, Andrea Sboner, Olivier Elemento, Scott T. Tagawa, David M. Nanus, Massimo Loda, Himisha Beltran, Brian D. Robinson, David S. Rickman

    Vydáno 2021
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  8. 8
    PARP Inhibition Suppresses GR–MYCN–CDK5–RB1–E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer

    PARP Inhibition Suppresses GR–MYCN–CDK5–RB1–E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer Autor Bo Liu, Likun Li, Guang Yang, Chuandong Geng, Yong Luo, Wenhui Wu, Ganiraju C. Manyam, Dimitrios Korentzelos, Sanghee Park, Zhe Tang, Cheng Wu, Zhenyang Dong, Michael Sigouros, Andrea Sboner, Himisha Beltran, Yu Chen, Paul G. Corn, Michael T. Tetzlaff, Patricia Troncoso, Bradley M. Broom, Timothy C. Thompson

    Vydáno 2019
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  9. 9
    Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers

    Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers Autor Jeremy Setton, Kevin Hadi, Zi-Ning Choo, Katherine S. Kuchin, Huasong Tian, Arnaud Da Cruz Paula, Joel Rosiene, Pier Selenica, Julie M. Behr, Xiaotong Yao, Aditya Deshpande, Michael Sigouros, Jyothi Manohar, Jones T. Nauseef, Juan Miguel Mosquera, Olivier Elemento, Britta Weigelt, Nadeem Riaz, Jorge S. Reis‐Filho, Simon N. Powell, Marcin Imieliński

    Vydáno 2023
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  10. 10
    Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer

    Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer Autor Loredana Puca, Katie Gavyert, Verena Sailer, Vincenza Conteduca, Étienne Dardenne, Michael Sigouros, Kumiko Isse, Megan Kearney, Aram Vosoughi, Luisa Fernandez, Heng Pan, Samaneh Motanagh, Judy Hess, Adam Donoghue, Andrea Sboner, Yuzhuo Wang, Ryan Dittamore, David S. Rickman, David M. Nanus, Scott T. Tagawa, Olivier Elemento, Juan Miguel Mosquera, Laura R. Saunders, Himisha Beltran

    Vydáno 2019
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  11. 11
    Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis

    Detecting Neuroendocrine Prostate Cancer Through Tissue-Informed Cell-Free DNA Methylation Analysis Autor Jacob E. Berchuck, Sylvan C. Baca, Heather M. McClure, Keegan Korthauer, Harrison Tsai, Pier Vitale Nuzzo, Kaitlin M. Kelleher, Monica He, John A. Steinharter, Soumya Zacharia, Sándor Spisák, Ji-Heui Seo, Vincenza Conteduca, Olivier Elemento, Joonghoon Auh, Michael Sigouros, Eva Corey, Michelle S. Hirsch, Mary‐Ellen Taplin, Toni K. Choueiri, Mark M. Pomerantz, Himisha Beltran, Matthew L. Freedman

    Vydáno 2021
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  12. 12
    Noninvasive Detection of Neuroendocrine Prostate Cancer through Targeted Cell-free DNA Methylation

    Noninvasive Detection of Neuroendocrine Prostate Cancer through Targeted Cell-free DNA Methylation Autor Gian Marco Franceschini, Orsetta Quaini, Kei Mizuno, Francesco Orlando, Yari Ciani, Sheng‐Yu Ku, Michael Sigouros, Emily Rothmann, Alicia Alonso, Matteo Benelli, Caterina Nardella, Joonghoon Auh, Dory Freeman, Brian Hanratty, Mohamed Adil, Olivier Elemento, Scott T. Tagawa, Felix Y. Feng, Orazio Caffo, Consuelo Buttigliero, Umberto Basso, Peter S. Nelson, Eva Corey, Michael C. Haffner, Gerhardt Attard, Ana M. Aparicio, Francesca Demichelis, Himisha Beltran

    Vydáno 2023
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  13. 13
    Extracellular Matrix in Synthetic Hydrogel‐Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors

    Extracellular Matrix in Synthetic Hydrogel‐Based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 Inhibitors Autor Matthew J. Mosquera, Sungwoong Kim, Rohan Bareja, Fang Zhou, Shuangyi Cai, Heng Pan, Muhammad Asad, M. Laura Martín, Michael Sigouros, Florencia P. Madorsky Rowdo, Sarah E. Ackermann, Jared Capuano, Jacob Bernheim, Cynthia Cheung, Ashley S. Doane, Nicholas J. Brady, Richa Singh, David S. Rickman, Varun V. Prabhu, Joshua E. Allen, Loredana Puca, Ahmet F. Coskun, Mark A. Rubin, Himisha Beltran, Juan Miguel Mosquera, Olivier Elemento, Ankur Singh

    Vydáno 2021
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  14. 14
    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation

    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation Autor Mona Teng, Jiacheng Guo, Xin Xu, Xinpei Ci, Yulin Mo, Yakup Kohen, Zuyao Ni, Sujun Chen, Weilong Guo, Martin Bakht, Sheng‐Yu Ku, Michael Sigouros, Wenqin Luo, Colette Maya Macarios, Ziting Xia, Moliang Chen, Sami Ul Haq, Wen‐Bin Yang, Alejandro Berlín, Theodorus van der Kwast, Leigh Ellis, Amina Zoubeidi, Gang Zheng, Jie Ming, Yuzhuo Wang, Haissi Cui, Benjamin H. Lok, Brian Raught, Himisha Beltran, Jun Qin, Housheng Hansen He

    Vydáno 2025
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  15. 15
    Patient derived organoids to model rare prostate cancer phenotypes

    Patient derived organoids to model rare prostate cancer phenotypes Autor Loredana Puca, Rohan Bareja, Davide Prandi, Reid Shaw, Matteo Benelli, Wouter R. Karthaus, Judy Hess, Michael Sigouros, Adam Donoghue, Myriam Kossaï, Dong Gao, Joanna Cyrta, Verena Sailer, Aram Vosoughi, Chantal Pauli, Yelena Churakova, Cynthia Cheung, Lesa D. Deonarine, Terra J. McNary, Rachele Rosati, Scott T. Tagawa, David M. Nanus, Juan Miguel Mosquera, Charles L. Sawyers, Yu Chen, Giorgio Inghirami, Rema Rao, Carla Grandori, Olivier Elemento, Andrea Sboner, Francesca Demichelis, Mark A. Rubin, Himisha Beltran

    Vydáno 2018
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  16. 16
    The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution

    The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution Autor Duy Nguyen, William F. Hooper, Weisi Liu, Timothy R. Chu, Heather Geiger, Jennifer Shelton, Minita Shah, Zoe R. Goldstein, Lara Winterkorn, Adrienne Helland, Michael Sigouros, Jyothi Manohar, Jenna E. Moyer, Majd Al Assaad, Alissa Semaan, Sandra Cohen, Florencia P. Madorsky Rowdo, David Wilkes, Mohamed Osman, Rahul Singh, Andrea Sboner, Henkel Valentine, Philip H. Abbosh, Scott T. Tagawa, David M. Nanus, Jones T. Nauseef, Cora N. Sternberg, Ana M. Molina, Douglas S. Scherr, Giorgio Inghirami, Juan Miguel Mosquera, Olivier Elemento, Nicolas Robine, Bishoy M. Faltas

    Vydáno 2024
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  17. 17
    Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition

    Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition Autor Florencia P. Madorsky Rowdo, Rachel Martini, Sarah E. Ackermann, Colin P. Tang, Marvel Tranquille, Adriana Irizarry, Ilkay Us, Omar Alawa, Jenna E. Moyer, Michael Sigouros, John Nguyen, Majd Al Assaad, Esther Cheng, Paula S. Ginter, Jyothi Manohar, Brian Stonaker, Richard Boateng, Joseph K. Oppong, Ernest Adjei, Baffour Awuah, Ishmael Kyei, Francis Aitpillah, Michael O. Adinku, Kwasi Ankomah, Ernest Osei‐Bonsu, Kofi K. Gyan, Syed A. Hoda, Lisa A. Newman, Juan Miguel Mosquera, Andrea Sboner, Olivier Elemento, Lukas E. Dow, Melissa B. Davis, M. Laura Martín

    Vydáno 2025
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  18. 18
    Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs

    Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs Autor Kevin Hadi, Xiaotong Yao, Julie M. Behr, Aditya Deshpande, Charalampos Xanthopoulakis, Huasong Tian, Sarah Kudman, Joel Rosiene, Madison Darmofal, Joseph DeRose, Rick Mortensen, Emily M. Adney, Alon Shaiber, Zoran Gajic, Michael Sigouros, Kenneth Eng, Jeremiah A. Wala, Kazimierz O. Wrzeszczyński, Kanika Arora, Minita Shah, Anne-Katrin Emde, Vanessa Felice, Mayu O. Frank, Robert B. Darnell, Mahmoud Ghandi, Franklin W. Huang, Sally M. Dewhurst, John Maciejowski, Titia de Lange, Jeremy Setton, Nadeem Riaz, Jorge S. Reis‐Filho, Simon N. Powell, David A. Knowles, Ed Reznik, Bud Mishra, Rameen Beroukhim, Michael C. Zody, Nicolas Robine, Kenji Oman, Carissa A. Sanchez, Mary K. Kuhner, Lucian P. Smith, Patricia C. Galipeau, Thomas G. Paulson, Brian J. Reid, Xiaohong Li, David Wilkes, Andrea Sboner, Juan Miguel Mosquera, Olivier Elemento, Marcin Imieliński

    Vydáno 2020
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