檢索結果 - Michael Seiler

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  1. 1
    Identifying microRNA/mRNA dysregulations in ovarian cancer

    Identifying microRNA/mRNA dysregulations in ovarian cancer 由 Gregory Miles, Michael Seiler, Lorna Rodriguez, G. Rajagopal, Gyan Bhanot

    出版 2012
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  2. 2
    Lactase Persistence and Lipid Pathway Selection in the Maasai

    Lactase Persistence and Lipid Pathway Selection in the Maasai 由 Kshitij Wagh, Aatish Bhatia, Gabriela Alexe, Anupama Reddy, Vijay Ravikumar, Michael Seiler, Michael Boemo, Ming Yao, Lee Cronk, Asad Naqvi, Shridar Ganesan, Arnold J. Levine, Gyan Bhanot

    出版 2012
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  3. 3
    Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma

    Identifying mRNA targets of microRNA dysregulated in cancer: with application to clear cell Renal Cell Carcinoma 由 Huiqing Liu, A. Rose Brannon, Anupama Reddy, Gabriela Alexe, Michael Seiler, Alexandra Arreola, Jay Oza, Ming Yao, David Juan, Louis S. Liou, Shridar Ganesan, Arnold J. Levine, W. Kimryn Rathmell, Gyan Bhanot

    出版 2010
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  4. 4
    Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma

    Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma 由 Sunniva Bjørklund, Anshuman Panda, Surendra Kumar, Michael Seiler, Doug Robinson, Jinesh S. Gheeya, Yao Ming, Grethe I.G. Alnæs, Deborah Toppmeyer, Margit Riis, Bjørn Naume, Anne‐Lise Børresen‐Dale, Vessela N. Kristensen, Shridar Ganesan, Gyan Bhanot

    出版 2017
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  5. 5
    Molecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals Distinct Subtypes and Survival Patterns

    Molecular Stratification of Clear Cell Renal Cell Carcinoma by Consensus Clustering Reveals Distinct Subtypes and Survival Patterns 由 A. Rose Brannon, Anupama Reddy, Michael Seiler, A. Arreola, Dominic T. Moore, Raj S. Pruthi, Eric Wallen, Matthew E. Nielsen, Hao Liu, Katherine L. Nathanson, Börje Ljungberg, Hongjuan Zhao, James D. Brooks, Shridar Ganesan, Gyan Bhanot, W. Kimryn Rathmell

    出版 2010
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  6. 6
    Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML

    Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML 由 Emily C. Wheeler, Benjamín Martín, William C. Doyle, Sofia Neaher, Caroline A. Conway, C Pitton, Rebecca A. Gorelov, Melanie Donahue, Johann C. Jann, Omar Abdel‐Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S. Garcia, Roger Belizaire, Karen Adelman, Zuzana Tóthová

    出版 2024
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  7. 7
    Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators

    Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators 由 Daniel Aird, Teng Teng, Chia‐Ling Huang, Ermira Pazolli, Deepti Banka, Kahlin Cheung-Ong, Cheryl Eifert, Craig Furman, Zhenhua J. Wu, Michael Seiler, Silvia Buonamici, Peter Fekkes, Craig Karr, James Palacino, Eunice Park, Peter G. Smith, Lihua Yu, Yoshiharu Mizui, Markus Warmuth, Agustin Chicas, Laura Corson, Ping Zhu

    出版 2019
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  8. 8
    Physiologic Expression of Sf3b1 K700E Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation

    Physiologic Expression of Sf3b1 K700E Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation 由 Esther A. Obeng, Ryan Chappell, Michael Seiler, Michelle C. Chen, Dean R. Campagna, Paul J. Schmidt, Rebekka K. Schneider, Allegra M. Lord, Lili Wang, Rutendo Gambe, Marie McConkey, Abdullah Mahmood Ali, Azra Raza, Lihua Yu, Silvia Buonamici, Peter G. Smith, Ann Mullally, Catherine J. Wu, Mark D. Fleming, Benjamin L. Ebert

    出版 2016
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  9. 9
    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS 由 Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al‐Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Treviño, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda

    出版 2018
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  10. 10
    Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex

    Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex 由 Teng Teng, Jennifer Tsai, Xiaoling Puyang, Michael Seiler, Shouyong Peng, Sudeep Prajapati, Daniel Aird, Silvia Buonamici, Benjamin Caleb, Betty Chan, Laura Corson, Jacob Feala, Peter Fekkes, Baudouin Gerard, Craig Karr, Manav Korpal, Xiang Liu, Jason T. Lowe, Yoshiharu Mizui, James Palacino, Eunice Park, Peter G. Smith, Vanitha Subramanian, Zhenhua J. Wu, Jian Zou, Lihua Yu, Agustin Chicas, Markus Warmuth, Nicholas Larsen, Ping Zhu

    出版 2017
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  11. 11
    Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations

    Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations 由 Stanley Chun-Wei Lee, Khrystyna North, Eun Hee Kim, Eunjung Jang, Esther A. Obeng, Sydney X. Lu, Bo Liu, Daichi Inoue, Akihide Yoshimi, Michelle Ki, Mirae Yeo, Xiao Jing Zhang, Min Kyung Kim, Hana Cho, Young Rock Chung, Justin Taylor, Benjamin H. Durham, Young Joon Kim, Alessandro Pastore, Sébastien Monette, James Palacino, Michael Seiler, Silvia Buonamici, Peter G. Smith, Benjamin L. Ebert, Robert K. Bradley, Omar Abdel‐Wahab

    出版 2018
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  12. 12
    Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies

    Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies 由 Elisa ten Hacken, Rebecca Valentin, Fara Faye Regis, Jing Sun, Shanye Yin, Lillian Werner, Jing Deng, Michaela Gruber, Jessica Wong, Mei Zheng, Amy Gill, Michael Seiler, Peter G. Smith, Michaël Thomas, Silvia Buonamici, Emanuela M. Ghia, Ekaterina Kim, Laura Z. Rassenti, Jan A. Burger, Thomas J. Kipps, Matthew Meyerson, Pavan Bachireddy, Lili Wang, Robin Reed, Donna Neuberg, Ruben D. Carrasco, Angela N. Brooks, Anthony Letai, Matthew S. Davids, Catherine J. Wu

    出版 2018
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  13. 13
    Sex-Biased<i>ZRSR2</i>Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis

    Sex-Biased<i>ZRSR2</i>Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis 由 Katsuhiro Togami, Sun Sook Chung, Vikas Madan, Christopher A.G. Booth, Christopher M. Kenyon, Lucía Cabal‐Hierro, Justin Taylor, Sunhee S. Kim, Gabriel K. Griffin, Mahmoud Ghandi, Jia Li, Yvonne Y. Li, Fanny Angelot‐Delettre, Sabeha Biichlé, Michael Seiler, Silvia Buonamici, Scott B. Lovitch, Abner Louissaint, Elizabeth A. Morgan, Fabrice Jardin, Pier Paolo Piccaluga, David M. Weinstock, Peter S. Hammerman, Henry Yang, Marina Konopleva, Naveen Pemmaraju, Francine Garnache‐Ottou, Omar Abdel‐Wahab, H. Phillip Koeffler, Andrew A. Lane

    出版 2021
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  14. 14
    H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

    H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers 由 Michael Seiler, Akihide Yoshimi, Rachel Darman, Betty Chan, Gregg F. Keaney, Michaël Thomas, Anant A. Agrawal, Benjamin Caleb, Alfredo Csibi, E. Egan Sean, Peter Fekkes, Craig Karr, Virginia M. Klimek, George Lai, Linda Lee, Pavan Kumar, Stanley Chun-Wei Lee, Xiang Liu, Crystal MacKenzie, Carol Meeske, Yoshiharu Mizui, Eric Padron, Eunice Park, Ermira Pazolli, Shouyong Peng, Sudeep Prajapati, Justin Taylor, Teng Teng, John Wang, Markus Warmuth, Huilan Yao, Lihua Yu, Ping Zhu, Omar Abdel‐Wahab, Peter G. Smith, Silvia Buonamici

    出版 2018
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  15. 15
    Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point

    Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point 由 Rachel Darman, Michael Seiler, Anant A. Agrawal, Kian‐Huat Lim, Shouyong Peng, Daniel Aird, Suzanna Bailey, Erica B. Bhavsar, Betty Chan, Simona Colla, Laura Corson, Jacob Feala, Peter Fekkes, Kana Ichikawa, Gregg F. Keaney, Linda Lee, Pavan Kumar, Kaiko Kunii, Crystal MacKenzie, Mark Matijevic, Yoshiharu Mizui, Khin Than Myint, Eun Sun Park, Xiaoling Puyang, Anand Selvaraj, Michael P. Thomas, Jennifer Tsai, John Y. Wang, Markus Warmuth, Hui Yang, Ping Zhu, Guillermo Garcia‐Manero, Richard R. Furman, Lihua Yu, Peter G. Smith, Silvia Buonamici

    出版 2015
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  16. 16
    Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia

    Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia 由 Lili Wang, Angela N. Brooks, Jean Fan, Youzhong Wan, Rutendo Gambe, Shuqiang Li, Sarah Hergert, Shanye Yin, Samuel S. Freeman, Joshua Z. Levin, Fan Lin, Michael Seiler, Silvia Buonamici, Peter G. Smith, Kevin F. Chau, Carrie Cibulskis, Wandi Zhang, Laura Z. Rassenti, Emanuela M. Ghia, Thomas J. Kipps, Stacey M. Fernandes, Donald B. Bloch, Dylan Kotliar, Dan A. Landau, Sachet A. Shukla, Jon C. Aster, Robin Reed, David S. DeLuca, Jennifer R. Brown, Donna Neuberg, Gad Getz, Kenneth J. Livak, Matthew Meyerson, Peter V. Kharchenko, Catherine J. Wu

    出版 2016
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  17. 17
    SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

    SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 由 Konstantinos Tzelepis, Étienne De Braekeleer, Demetrios Aspris, Isaia Barbieri, M. S. Vijayabaskar, Wen‐Hsin Liu, Malgorzata Gozdecka, Emmanouil Metzakopian, Hamish D. Toop, Monika Dudek, Samuel C. Robson, Francisco Hermida‐Prado, Yang Yu, Roya Babaei‐Jadidi, Dimitrios A. Garyfallos, Hannes Ponstingl, João M.L. Dias, Paolo Gallipoli, Michael Seiler, Silvia Buonamici, Binje Vick, Andrew J. Bannister, Roland Rad, Rab K. Prinjha, John C. Marioni, Brian J.P. Huntly, Jennifer Batson, Jonathan C. Morris, Cristina Pina, Allan Bradley, Irmela Jeremias, David O. Bates, Kosuke Yusa, Tony Kouzarides, George S. Vassiliou

    出版 2018
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  18. 18
    Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer

    Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer 由 Manav Korpal, Xiaoling Puyang, Zhenhua J. Wu, Roland Seiler, Craig Furman, Htoo Zarni Oo, Michael Seiler, Sean Irwin, Vanitha Subramanian, Jaya Julie Joshi, Chris Kedong Wang, Victoria Rimkunas, Davide Tortora, Hua Yang, Namita Kumar, Galina Kuznetsov, Mark Matijevic, Jesse C. Chow, Pavan Kumar, Jian Zou, Jacob Feala, Laura Corson, Ryan E. Henry, Anand Selvaraj, Allison Davis, Kristjan Bloudoff, James J. Douglas, Bernhard Kiss, Morgan E. Roberts, Ladan Fazli, Peter C. Black, Peter Fekkes, Peter G. Smith, Markus Warmuth, Lihua Yu, Ming‐Hong Hao, Nicholas Larsen, Mads Daugaard, Ping Zhu

    出版 2017
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  19. 19
    Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

    Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types 由 Michael Seiler, Shouyong Peng, Anant A. Agrawal, James Palacino, Teng Teng, Ping Zhu, Peter G. Smith, Silvia Buonamici, Lihua Yu, Rory Johnson, John A. Demchok, Ina Felau, Melpomeni Kasapi, Martin L. Ferguson, Carolyn M. Hutter, Heidi J. Sofia, Roy Tarnuzzer, Linghua Wang, Liming Yang, Jean C. Zenklusen, Jiashan Zhang, Sudha Chudamani, Jia Liu, Laxmi Lolla, Rashi Naresh, Todd Pihl, Qiang Sun, Yunhu Wan, Ye Wu, Juok Cho, Timothy Defreitas, Scott Frazer, Nils Gehlenborg, Gad Getz, David I. Heiman, Jaegil Kim, Michael S. Lawrence, Pei Lin, Thomas J. Giordano, Michael S. Noble, Gordon Saksena, Doug Voet, Hailei Zhang, Brady Bernard, Nyasha Chambwe, Varsha Dhankani, Theo Knijnenburg, Roger Kramer, Kalle Leinonen, Yuexin Liu, Michael Miller, Sheila M. Reynolds, Ilya Shmulevich, Vésteinn Thórsson, Wei Zhang, Rehan Akbani, Bradley M. Broom, Apurva M. Hegde, Zhenlin Ju, Rupa S. Kanchi, Anil Korkut, Jun Li, Han Liang, Shiyun Ling, Wenbin Liu, Yiling Lu, Gordon B. Mills, Kwok-Shing Ng, Arvind Rao, Michaël Ryan, Jing Wang, John N. Weinstein, Jiexin Zhang, Adam Abeshouse, Joshua Armenia, Debyani Chakravarty, Walid K. Chatila, Ino de Bruijn, Galen F. Gao, Benjamin Groß, Zachary Heins, Ritika Kundra, Konnor La, Marc Ladanyi, Augustin Luna, Moriah G. Nissan, Angelica Ochoa, Sarah Phillips, Ed Reznik, Francisco Sánchez-Vega, Chris Sander, Nikolaus Schultz, Robert P. Sheridan, S. Onur Sumer, Yichao Sun, Barry S. Taylor, Jioajiao Wang, Hongxin Zhang, Pavana Anur, Myron Peto

    出版 2018
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  20. 20
    The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma

    The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma 由 Caleb Davis, Christopher J. Ricketts, Min Wang, Lixing Yang, Andrew D. Cherniack, Hui Shen, Christian Buhay, Hyo-Jin Kang, Sang Cheol Kim, Catherine C. Fahey, Kathryn E. Hacker, Gyan Bhanot, Dmitry A. Gordenin, Andy Chu, Preethi H. Gunaratne, Michael Biehl, Sahil Seth, Benny Abraham Kaipparettu, Christopher A. Bristow, Lawrence A. Donehower, Eric Wallen, Angela Smith, Satish K. Tickoo, Pheroze Tamboli, Victor E. Reuter, Laura S. Schmidt, James J. Hsieh, Toni K. Choueiri, A. Ari Hakimi, Lynda Chin, Matthew Meyerson, Raju Kucherlapati, Woong‐Yang Park, A. Gordon Robertson, Peter W. Laird, Elizabeth P. Henske, David J. Kwiatkowski, Peter J. Park, Margaret Morgan, Brian Shuch, Donna M. Muzny, David A. Wheeler, W. Marston Linehan, Richard A. Gibbs, W. Kimryn Rathmell, Chad J. Creighton, Chad J. Creighton, Caleb Davis, Margaret Morgan, Preethi H. Gunaratne, Lawrence A. Donehower, Benny Abraham Kaipparettu, David A. Wheeler, Richard A. Gibbs, Sabina Signoretti, Andrew D. Cherniack, A. Gordon Robertson, Andy Chu, Toni K. Choueiri, Elizabeth P. Henske, David J. Kwiatkowski, Victor E. Reuter, James J. Hsieh, A. Ari Hakimi, Satish K. Tickoo, Christopher J. Ricketts, W. Marston Linehan, Laura S. Schmidt, Dmitry A. Gordenin, Gyan Bhanot, Michael Seiler, Pheroze Tamboli, W. Kimryn Rathmell, Catherine C. Fahey, Kathryn E. Hacker, Angela Smith, Eric Wallen, Hui Shen, Peter W. Laird, Brian Shuch, Donna M. Muzny, Christian Buhay, Min Wang, Hsu Chao, Mike Dahdouli, Xi Liu, Nipun Kakkar, Jeffrey G. Reid, Brittany Downs, Jennifer Drummond, Donna Morton, HarshaVardhan Doddapaneni, Lora Lewis, Adam C. English, Qingchang Meng, Christie Kovar, Qiaoyan Wang, Walker Hale, Alicia Hawes, Divya Kalra

    出版 2014
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