Resultados de búsqueda - Michael S. Cosgrove

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  1. 1
    Mixed lineage leukemia: a structure–function perspective of the MLL1 protein

    Mixed lineage leukemia: a structure–function perspective of the MLL1 protein por Michael S. Cosgrove, Anamika Patel

    Publicado 2010
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  2. 2
    Structure of WDR5 Bound to Mixed Lineage Leukemia Protein-1 Peptide

    Structure of WDR5 Bound to Mixed Lineage Leukemia Protein-1 Peptide por Anamika Patel, Venkatasubramanian Dharmarajan, Michael S. Cosgrove

    Publicado 2008
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  3. 3
    A Novel Non-SET Domain Multi-subunit Methyltransferase Required for Sequential Nucleosomal Histone H3 Methylation by the Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex

    A Novel Non-SET Domain Multi-subunit Methyltransferase Required for Sequential Nucleosomal Histone H3 Methylation by the Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex por Anamika Patel, Valarie E. Vought, Venkatasubramanian Dharmarajan, Michael S. Cosgrove

    Publicado 2010
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  4. 4
    On the Mechanism of Multiple Lysine Methylation by the Human Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex

    On the Mechanism of Multiple Lysine Methylation by the Human Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex por Anamika Patel, Venkatasubramanian Dharmarajan, Valarie E. Vought, Michael S. Cosgrove

    Publicado 2009
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  5. 5
    A Conserved Arginine-containing Motif Crucial for the Assembly and Enzymatic Activity of the Mixed Lineage Leukemia Protein-1 Core Complex

    A Conserved Arginine-containing Motif Crucial for the Assembly and Enzymatic Activity of the Mixed Lineage Leukemia Protein-1 Core Complex por Anamika Patel, Valarie E. Vought, Venkatasubramanian Dharmarajan, Michael S. Cosgrove

    Publicado 2008
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  6. 6
    Biochemical Reconstitution and Phylogenetic Comparison of Human SET1 Family Core Complexes Involved in Histone Methylation

    Biochemical Reconstitution and Phylogenetic Comparison of Human SET1 Family Core Complexes Involved in Histone Methylation por Stephen A. Shinsky, Kelsey E. Monteith, Susan Viggiano, Michael S. Cosgrove

    Publicado 2015
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  7. 7
    Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases

    Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases por Venkatasubramanian Dharmarajan, Jeong‐Heon Lee, Anamika Patel, David G. Skalnik, Michael S. Cosgrove

    Publicado 2012
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  8. 8
    Structure of a Sir2 Enzyme Bound to an Acetylated p53 Peptide

    Structure of a Sir2 Enzyme Bound to an Acetylated p53 Peptide por José L. Avalos‬, Ivana Celic, Shabazz Muhammad, Michael S. Cosgrove, Jef D. Boeke, Cynthia Wolberger

    Publicado 2002
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  9. 9
    A Non-Active-Site SET Domain Surface Crucial for the Interaction of MLL1 and the RbBP5/Ash2L Heterodimer within MLL Family Core Complexes

    A Non-Active-Site SET Domain Surface Crucial for the Interaction of MLL1 and the RbBP5/Ash2L Heterodimer within MLL Family Core Complexes por Stephen A. Shinsky, Michael S. Hu, Valarie E. Vought, Sarah Ng, Michael J. Bamshad, Jay Shendure, Michael S. Cosgrove

    Publicado 2014
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  10. 10
    Insights into the Role of Histone H3 and Histone H4 Core Modifiable Residues in <i>Saccharomyces cerevisiae</i>

    Insights into the Role of Histone H3 and Histone H4 Core Modifiable Residues in <i>Saccharomyces cerevisiae</i> por Edel M. Hyland, Michael S. Cosgrove, Henrik Molina, Dongxia Wang, Akhilesh Pandey, Robert J. Cottee, Jef D. Boeke

    Publicado 2005
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  11. 11
    Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes

    Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltrans... por Nilda L. Alicea‐Velázquez, Stephen A. Shinsky, Daniel M. Loh, Jeong‐Heon Lee, David G. Skalnik, Michael S. Cosgrove

    Publicado 2016
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  12. 12
    Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing

    Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing por Feng Tie, Rakhee Banerjee, Alina Saiakhova, Benny Howard, Kelsey E. Monteith, Peter C. Scacheri, Michael S. Cosgrove, Peter J. Harte

    Publicado 2014
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  13. 13
    ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner

    ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner por Thuy P. Dao, Brian Martyniak, Ashley J. Canning, Yongna Lei, Erica G. Colicino, Michael S. Cosgrove, Heidi Hehnly, Carlos A. Castañeda

    Publicado 2019
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  14. 14
    Mechanistic insights into enhancement or inhibition of phase separation by different polyubiquitin chains

    Mechanistic insights into enhancement or inhibition of phase separation by different polyubiquitin chains por Thuy P. Dao, Yiran Yang, Maria F. Presti, Michael S. Cosgrove, Jesse B. Hopkins, Weikang Ma, Stewart N. Loh, Carlos A. Castañeda

    Publicado 2022
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  15. 15
    EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction

    EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction por Jing Zhao, Alan J. Blayney, Xiaorong Liu, Lauren Gandy, Weihua Jin, Lufeng Yan, Jeung-Hoi Ha, Ashley J. Canning, Michael S. Connelly, Chao Yang, Xinyue Liu, Yuanyuan Xiao, Michael S. Cosgrove, Sozanne R. Solmaz, Yingkai Zhang, David Ban, Jianhan Chen, Stewart N. Loh, Chunyu Wang

    Publicado 2021
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  16. 16
    An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability

    An acetylation-mediated chromatin switch governs H3K4 methylation read-write capability por Kanishk Jain, Matthew R. Marunde, Jonathan M. Burg, Susan L. Gloor, Faith M Joseph, Karl F. Poncha, Zachary B Gillespie, Keli L. Rodriguez, Irina K. Popova, Nathan W Hall, Anup Vaidya, Sarah A. Howard, Hailey F. Taylor, Laylo Mukhsinova, Ugochi C. Onuoha, Emily F. Patteson, Spencer W Cooke, Bethany C. Taylor, Ellen N Weinzapfel, Marcus A. Cheek, Matthew J. Meiners, Geoffrey Fox, Kevin Namitz, Martis W. Cowles, Krzysztof Krajewski, Zu‐Wen Sun, Michael S. Cosgrove, Nicolas L. Young, Michael‐Christopher Keogh, Brian D. Strahl

    Publicado 2023
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