檢索結果 - Michael A. Lodato
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ATM-deficiency-induced microglial activation promotes neurodegeneration in ataxia-telangiectasia 由 Jenny Lai, Didem Demirbas, Junho Kim, Ailsa M. Jeffries, Allie Tolles, Junseok Park, Thomas W. Chittenden, Patrick G. Buckley, Timothy W. Yu, Michael A. Lodato, Eunjung Alice Lee
出版 2023Artigo -
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Reprogramming of Postnatal Neurons into Induced Pluripotent Stem Cells by Defined Factors 由 Jong‐Pil Kim, Christopher J. Lengner, Oktay Kirak, Jacob H. Hanna, John P. Cassady, Michael A. Lodato, Su Wu, Dina A. Faddah, Eveline J. Steine, Qing Gao, Dongdong Fu, Meelad M. Dawlaty, Rudolf Jaenisch
出版 2011Artigo -
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Histone H3K27ac separates active from poised enhancers and predicts developmental state 由 Menno P. Creyghton, Albert W. Cheng, G. Grant Welstead, Tristan Kooistra, Bryce W. Carey, Eveline J. Steine, Jacob H. Hanna, Michael A. Lodato, Garrett M. Frampton, Phillip A. Sharp, Laurie A. Boyer, Richard A. Young, Rudolf Jaenisch
出版 2010Artigo -
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Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity 由 Sangita Choudhury, August Yue Huang, Jun‐Ho Kim, Zinan Zhou, Katherine Morillo, Eduardo A. Maury, Jessica W. Tsai, Michael B. Miller, Michael A. Lodato, Sarah Araten, Nazia Hilal, Eunjung Alice Lee, Ming Hui Chen, Christopher A. Walsh
出版 2022Artigo -
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Somatic mutation in single human neurons tracks developmental and transcriptional history 由 Michael A. Lodato, Mollie B. Woodworth, Semin Lee, Gilad D. Evrony, Bhaven K. Mehta, Amir Karger, Soohyun Lee, Thomas W. Chittenden, Alissa M. D’Gama, Xuyu Cai, Lovelace J. Luquette, Eunjung Lee, Peter J. Park, Christopher A. Walsh
出版 2015Artigo -
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Linked-read analysis identifies mutations in single-cell DNA-sequencing data 由 Craig L. Bohrson, Alison R. Barton, Michael A. Lodato, Rachel E. Rodin, Lovelace J. Luquette, Vinay Viswanadham, D. Gulhan, Isidro Cortés‐Ciriano, Maxwell A. Sherman, Min‐Seok Kwon, Michael E. Coulter, Alon Galor, Christopher A. Walsh, Peter J. Park
出版 2019Artigo -
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Aging and neurodegeneration are associated with increased mutations in single human neurons 由 Michael A. Lodato, Rachel E. Rodin, Craig L. Bohrson, Michael E. Coulter, Alison R. Barton, Min‐Seok Kwon, Maxwell A. Sherman, Carl Vitzthum, Lovelace J. Luquette, Chandri Yandava, Pengwei Yang, Thomas W. Chittenden, Nicole E. Hatem, Steven C. Ryu, Mollie B. Woodworth, Peter J. Park, Christopher A. Walsh
出版 2017Artigo -
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Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements 由 Lovelace J. Luquette, Michael B. Miller, Zinan Zhou, Craig L. Bohrson, Yifan Zhao, Hu Jin, D. Gulhan, Javier Ganz, Sara Bizzotto, Samantha L. Kirkham, Tino Hochepied, Claude Libert, Alon Galor, Junho Kim, Michael A. Lodato, Juan I. Garaycoechea, Charles Gawad, Jay West, Christopher A. Walsh, Peter J. Park
出版 2022Artigo -
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Somatic genomic changes in single Alzheimer’s disease neurons 由 Michael B. Miller, August Yue Huang, Jun‐Ho Kim, Zinan Zhou, Samantha L. Kirkham, Eduardo A. Maury, Jennifer S. Ziegenfuss, Hannah C. Reed, Jennifer E. Neil, Lariza M. Rento, Steven C. Ryu, C. Chanthia, Lovelace J. Luquette, Heather M. Ames, Derek H. Oakley, Matthew P. Frosch, Bradley T. Hyman, Michael A. Lodato, Eunjung Alice Lee, Christopher A. Walsh
出版 2022Artigo -
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Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex 由 Sonia N. Kim, Vinay Viswanadham, Ryan N. Doan, Yanmei Dou, Sara Bizzotto, Sattar Khoshkhoo, August Yue Huang, Rebecca C. Yeh, Brian Chhouk, Alex Truong, Kathleen M. Chappell, Marc Beaudin, Alison R. Barton, Shyam K. Akula, Lariza M. Rento, Michael A. Lodato, Javier Ganz, Ryan A. Szeto, Pengpeng Li, Jessica W. Tsai, Robert Hill, Peter J. Park, Christopher A. Walsh
出版 2023Pré-impressão -
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Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network 由 Michael J. McConnell, John V. Moran, Alexej Abyzov, Schahram Akbarian, Taejeong Bae, Isidro Cortés‐Ciriano, Jennifer A. Erwin, Liana Fasching, Diane A. Flasch, Donald Freed, Javier Ganz, Andrew E. Jaffe, Kenneth Y. Kwan, Min‐Seok Kwon, Michael A. Lodato, Ryan E. Mills, Apuã C.M. Paquola, Rachel E. Rodin, Chaggai Rosenbluh, Nenad Šestan, Maxwell A. Sherman, Joo Heon Shin, Saera Song, Richard E. Straub, Jeremy Thorpe, Daniel R. Weinberger, Alexander E. Urban, Bo Zhou, Fred H. Gage, Thomas Lehner, Geetha Senthil, Christopher A. Walsh, Andrew Chess, Eric Courchesne, Joseph G. Gleeson, Jeffrey M. Kidd, Peter J. Park, Jonathan Pevsner, Flora M. Vaccarino, Alison R. Barton, Stefan Bekiranov, Craig L. Bohrson, Ian Burbulis, William D. Chronister, Gianfilippo Coppola, Kenneth Daily, Alissa M. D’Gama, Sarah B. Emery, Trenton J. Frisbie, Tianliuyun Gao, Attila Gulyás-Kovács, Mark F. Haakenson, Jason M. Keil, Huira C. Kopera, Mandy M. Lam, Eunjung Alice Lee, Tomàs Marquès‐Bonet, Gary W. Mathern, John B. Moldovan, Matthew T. Oetjens, Larsson Omberg, Mette A. Peters, Sirisha Pochareddy, Tiziano Pramparo, Aakrosh Ratan, Tiziana Sanavia, Lei Shi, Mario Škarica, Jia Wang, Meiyan Wang, Yifan Wang, Margaret E. Wierman, Matthew J. Wolpert, Mollie B. Woodworth, Xuefang Zhao, Weichen Zhou
出版 2017Revisão -
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Somatic mosaicism reveals clonal distributions of neocortical development 由 Martin W. Breuss, Xiaoxu Yang, Johannes C. M. Schlachetzki, Danny Antaki, Addison J. Lana, Xin Xu, Changuk Chung, Guoliang Chai, Valentina Stanley, Qiong Song, Traci Fang Newmeyer, An T. Nguyen, S O'Brien, Marten A. Hoeksema, Beibei Cao, Alexi Nott, Jennifer McEvoy‐Venneri, Martina P. Pasillas, Scott T. Barton, Brett Copeland, Shareef Nahas, Lucitia Van Der Kraan, Yan Ding, Joseph G. Gleeson, Martin W. Breuss, Xiaoxu Yang, Danny Antaki, Changuk Chung, Dan Averbuj, Eric Courchesne, Laurel Ball, Subhojit Roy, Daniel R. Weinberger, Andrew E. Jaffe, Apuã C.M. Paquola, Jennifer A. Erwin, Jooheon Shin, Michael J. McConnell, Richard E. Straub, Rujuta Narurkar, Gary W. Mathern, Christopher A. Walsh, Alice Lee, August Yue Huang, Alissa M. D’Gama, Caroline Dias, Eduardo A. Maury, Javier Ganz, Michael A. Lodato, Michael B. Miller, Pengpeng Li, Rachel E. Rodin, Rebeca Borges-Monroy, Robert Hill, Sara Bizzotto, Sattar Khoshkhoo, Sonia Kim, Zinan Zhou, Peter J. Park, Alison R. Barton, Alon Galor, Chong Chu, Craig L. Bohrson, D. Gulhan, Elaine T. Lim, Eun‐Cheon Lim, Giorgio Melloni, Isidro Cortes, Jake Lee, Joe Luquette, Lixing Yang, Maxwell A. Sherman, Michael E. Coulter, Min‐Seok Kwon, Semin Lee, Soo In Lee, Vinary Viswanadham, Yanmei Dou, Andrew Chess, Attila Jones, Chaggai Rosenbluh, Schahram Akbarian, Ben Langmead, Jeremy Thorpe, Sean Cho, Alexej Abyzov, Taejeong Bae, Yeongjun Jang, Yifan Wang, Cindy Molitor, Mette A. Peters, Fred H. Gage, Meiyan Wang, Patrick Reed, Sara B. Linker, Alexander E. Urban, Bo Zhou, Reenal Pattni, Xiaowei Zhu, Aitor Serres Amero
出版 2022Artigo -
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Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability 由 Taejeong Bae, Liana Fasching, Yifan Wang, Joo Heon Shin, Milovan Šuvakov, Yeongjun Jang, Scott Norton, Caroline Dias, Jessica Mariani, Alexandre Jourdon, Feinan Wu, Arijit Panda, Reenal Pattni, Yasmine Chahine, Rebecca C. Yeh, Rosalinda C. Roberts, Anita Hüttner, Joel E. Kleinman, Thomas M. Hyde, Richard E. Straub, Christopher A. Walsh, Alexander E. Urban, James F. Leckman, Daniel R. Weinberger, Flora M. Vaccarino, Alexej Abyzov, Christopher A. Walsh, Peter J. Park, Nenad Šestan, Daniel R. Weinberger, John V. Moran, Fred H. Gage, Flora M. Vaccarino, Joseph G. Gleeson, Gary W. Mathern, Eric Courchesne, Subhojit Roy, Andrew Chess, Schahram Akbarian, Sara Bizzotto, Michael E. Coulter, Caroline Dias, Alissa M. D’Gama, Javier Ganz, Robert Hill, August Yue Huang, Sattar Khoshkhoo, Sonia Kim, Alice Lee, Michael A. Lodato, Eduardo A. Maury, Michael Miller, Rebeca Borges-Monroy, Rachel E. Rodin, Zinan Zhou, Craig L. Bohrson, Chong Chu, Isidro Cortés‐Ciriano, Yanmei Dou, Alon Galor, D. Gulhan, Min‐Seok Kwon, Joe Luquette, Maxwell A. Sherman, Vinay Viswanadham, Attila Jones, Chaggai Rosenbluh, Sean Cho, Ben Langmead, Jeremy Thorpe, Jennifer A. Erwin, Andrew E. Jaffe, Michael J. McConnell, Rujuta Narurkar, Apuã C.M. Paquola, Jooheon Shin, Richard E. Straub, Alexej Abyzov, Taejeong Bae, Yeongjun Jang, Yifan Wang, Cindy Molitor, Mette A. Peters, Sara B. Linker, Patrick Reed, Meiyan Wang, Alexander E. Urban, Bo Zhou, Xiaowei Zhu, Reenal Pattni, Aitor Serres Amero, David Juan, Irene Lobón, Tomàs Marquès‐Bonet, Manuel Solis Moruno, Raquel García Pérez, Inna Povolotskaya, Eduardo Soriano, Danny Antaki, Dan Averbuj
出版 2022Artigo
相關主題
Biology
Genetics
Gene
Somatic cell
Neuroscience
Cell biology
Mutation
Medicine
Transcription factor
DNA
Genome
Disease
Germline mutation
Pathology
Reprogramming
Cell
Cellular differentiation
DNA damage
Embryonic stem cell
Gene expression
Germline
Induced pluripotent stem cell
Lineage (genetic)
Neurodegeneration
Computational biology
Enhancer
Human brain
Ataxia-telangiectasia
Cell type
Cerebral cortex