Výsledky vyhledávání - Michael A. Lodato

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  1. 1
    Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms

    Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms Autor Michael A. Lodato, Christopher A. Walsh

    Vydáno 2019
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  2. 2
    SapT, a lanthionine‐containing peptide involved in aerial hyphae formation in the streptomycetes

    SapT, a lanthionine‐containing peptide involved in aerial hyphae formation in the streptomycetes Autor Shinya Kodani, Michael A. Lodato, Marcus C. Durrant, Francis Picart, Joanne M. Willey

    Vydáno 2005
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  3. 3
    SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

    SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State Autor Michael A. Lodato, Christopher Ng, Joseph A. Wamstad, Albert W. Cheng, Kevin K. Thai, Ernest Fraenkel, Rudolf Jaenisch, Laurie A. Boyer

    Vydáno 2013
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  4. 4
    Persistent DNA damage associated with ATM kinase deficiency promotes microglial dysfunction

    Persistent DNA damage associated with ATM kinase deficiency promotes microglial dysfunction Autor Julie Bourseguin, Wen Cheng, Emily Talbot, Liana Hardy, Jenny Lai, Ailsa M. Jeffries, Michael A. Lodato, Eunjung Alice Lee, S. V. Khoronenkova

    Vydáno 2022
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  5. 5
    A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

    A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types Autor Marius Wernig, Christopher J. Lengner, Jacob H. Hanna, Michael A. Lodato, Eveline J. Steine, Ruth K. Foreman, Judith Staerk, Styliani Markoulaki, Rudolf Jaenisch

    Vydáno 2008
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  6. 6
    H2AZ Is Enriched at Polycomb Complex Target Genes in ES Cells and Is Necessary for Lineage Commitment

    H2AZ Is Enriched at Polycomb Complex Target Genes in ES Cells and Is Necessary for Lineage Commitment Autor Menno P. Creyghton, Styliani Markoulaki, Stuart S. Levine, Jacob H. Hanna, Michael A. Lodato, Ky Sha, Richard A. Young, Rudolf Jaenisch, Laurie A. Boyer

    Vydáno 2008
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  7. 7
    ATM-deficiency-induced microglial activation promotes neurodegeneration in ataxia-telangiectasia

    ATM-deficiency-induced microglial activation promotes neurodegeneration in ataxia-telangiectasia Autor Jenny Lai, Didem Demirbas, Junho Kim, Ailsa M. Jeffries, Allie Tolles, Junseok Park, Thomas W. Chittenden, Patrick G. Buckley, Timothy W. Yu, Michael A. Lodato, Eunjung Alice Lee

    Vydáno 2023
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  8. 8
    Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts

    Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts Autor Jong‐Pil Kim, Susan C. Su, Haoyi Wang, Albert W. Cheng, John P. Cassady, Michael A. Lodato, Christopher J. Lengner, Chee-Yeun Chung, Meelad M. Dawlaty, Li‐Huei Tsai, Rudolf Jaenisch

    Vydáno 2011
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  9. 9
    Reprogramming of Postnatal Neurons into Induced Pluripotent Stem Cells by Defined Factors

    Reprogramming of Postnatal Neurons into Induced Pluripotent Stem Cells by Defined Factors Autor Jong‐Pil Kim, Christopher J. Lengner, Oktay Kirak, Jacob H. Hanna, John P. Cassady, Michael A. Lodato, Su Wu, Dina A. Faddah, Eveline J. Steine, Qing Gao, Dongdong Fu, Meelad M. Dawlaty, Rudolf Jaenisch

    Vydáno 2011
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  10. 10
    Histone H3K27ac separates active from poised enhancers and predicts developmental state

    Histone H3K27ac separates active from poised enhancers and predicts developmental state Autor Menno P. Creyghton, Albert W. Cheng, G. Grant Welstead, Tristan Kooistra, Bryce W. Carey, Eveline J. Steine, Jacob H. Hanna, Michael A. Lodato, Garrett M. Frampton, Phillip A. Sharp, Laurie A. Boyer, Richard A. Young, Rudolf Jaenisch

    Vydáno 2010
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  11. 11
    Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity

    Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity Autor Sangita Choudhury, August Yue Huang, Jun‐Ho Kim, Zinan Zhou, Katherine Morillo, Eduardo A. Maury, Jessica W. Tsai, Michael B. Miller, Michael A. Lodato, Sarah Araten, Nazia Hilal, Eunjung Alice Lee, Ming Hui Chen, Christopher A. Walsh

    Vydáno 2022
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  12. 12
    Somatic mutation in single human neurons tracks developmental and transcriptional history

    Somatic mutation in single human neurons tracks developmental and transcriptional history Autor Michael A. Lodato, Mollie B. Woodworth, Semin Lee, Gilad D. Evrony, Bhaven K. Mehta, Amir Karger, Soohyun Lee, Thomas W. Chittenden, Alissa M. D’Gama, Xuyu Cai, Lovelace J. Luquette, Eunjung Lee, Peter J. Park, Christopher A. Walsh

    Vydáno 2015
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  13. 13
    Linked-read analysis identifies mutations in single-cell DNA-sequencing data

    Linked-read analysis identifies mutations in single-cell DNA-sequencing data Autor Craig L. Bohrson, Alison R. Barton, Michael A. Lodato, Rachel E. Rodin, Lovelace J. Luquette, Vinay Viswanadham, D. Gulhan, Isidro Cortés‐Ciriano, Maxwell A. Sherman, Min‐Seok Kwon, Michael E. Coulter, Alon Galor, Christopher A. Walsh, Peter J. Park

    Vydáno 2019
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  14. 14
    Aging and neurodegeneration are associated with increased mutations in single human neurons

    Aging and neurodegeneration are associated with increased mutations in single human neurons Autor Michael A. Lodato, Rachel E. Rodin, Craig L. Bohrson, Michael E. Coulter, Alison R. Barton, Min‐Seok Kwon, Maxwell A. Sherman, Carl Vitzthum, Lovelace J. Luquette, Chandri Yandava, Pengwei Yang, Thomas W. Chittenden, Nicole E. Hatem, Steven C. Ryu, Mollie B. Woodworth, Peter J. Park, Christopher A. Walsh

    Vydáno 2017
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  15. 15
    Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements

    Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements Autor Lovelace J. Luquette, Michael B. Miller, Zinan Zhou, Craig L. Bohrson, Yifan Zhao, Hu Jin, D. Gulhan, Javier Ganz, Sara Bizzotto, Samantha L. Kirkham, Tino Hochepied, Claude Libert, Alon Galor, Junho Kim, Michael A. Lodato, Juan I. Garaycoechea, Charles Gawad, Jay West, Christopher A. Walsh, Peter J. Park

    Vydáno 2022
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  16. 16
    Somatic genomic changes in single Alzheimer’s disease neurons

    Somatic genomic changes in single Alzheimer’s disease neurons Autor Michael B. Miller, August Yue Huang, Jun‐Ho Kim, Zinan Zhou, Samantha L. Kirkham, Eduardo A. Maury, Jennifer S. Ziegenfuss, Hannah C. Reed, Jennifer E. Neil, Lariza M. Rento, Steven C. Ryu, C. Chanthia, Lovelace J. Luquette, Heather M. Ames, Derek H. Oakley, Matthew P. Frosch, Bradley T. Hyman, Michael A. Lodato, Eunjung Alice Lee, Christopher A. Walsh

    Vydáno 2022
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  17. 17
    Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex

    Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex Autor Sonia N. Kim, Vinay Viswanadham, Ryan N. Doan, Yanmei Dou, Sara Bizzotto, Sattar Khoshkhoo, August Yue Huang, Rebecca C. Yeh, Brian Chhouk, Alex Truong, Kathleen M. Chappell, Marc Beaudin, Alison R. Barton, Shyam K. Akula, Lariza M. Rento, Michael A. Lodato, Javier Ganz, Ryan A. Szeto, Pengpeng Li, Jessica W. Tsai, Robert Hill, Peter J. Park, Christopher A. Walsh

    Vydáno 2023
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  18. 18
    Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network

    Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network Autor Michael J. McConnell, John V. Moran, Alexej Abyzov, Schahram Akbarian, Taejeong Bae, Isidro Cortés‐Ciriano, Jennifer A. Erwin, Liana Fasching, Diane A. Flasch, Donald Freed, Javier Ganz, Andrew E. Jaffe, Kenneth Y. Kwan, Min‐Seok Kwon, Michael A. Lodato, Ryan E. Mills, Apuã C.M. Paquola, Rachel E. Rodin, Chaggai Rosenbluh, Nenad Šestan, Maxwell A. Sherman, Joo Heon Shin, Saera Song, Richard E. Straub, Jeremy Thorpe, Daniel R. Weinberger, Alexander E. Urban, Bo Zhou, Fred H. Gage, Thomas Lehner, Geetha Senthil, Christopher A. Walsh, Andrew Chess, Eric Courchesne, Joseph G. Gleeson, Jeffrey M. Kidd, Peter J. Park, Jonathan Pevsner, Flora M. Vaccarino, Alison R. Barton, Stefan Bekiranov, Craig L. Bohrson, Ian Burbulis, William D. Chronister, Gianfilippo Coppola, Kenneth Daily, Alissa M. D’Gama, Sarah B. Emery, Trenton J. Frisbie, Tianliuyun Gao, Attila Gulyás-Kovács, Mark F. Haakenson, Jason M. Keil, Huira C. Kopera, Mandy M. Lam, Eunjung Alice Lee, Tomàs Marquès‐Bonet, Gary W. Mathern, John B. Moldovan, Matthew T. Oetjens, Larsson Omberg, Mette A. Peters, Sirisha Pochareddy, Tiziano Pramparo, Aakrosh Ratan, Tiziana Sanavia, Lei Shi, Mario Škarica, Jia Wang, Meiyan Wang, Yifan Wang, Margaret E. Wierman, Matthew J. Wolpert, Mollie B. Woodworth, Xuefang Zhao, Weichen Zhou

    Vydáno 2017
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  19. 19
    Somatic mosaicism reveals clonal distributions of neocortical development

    Somatic mosaicism reveals clonal distributions of neocortical development Autor Martin W. Breuss, Xiaoxu Yang, Johannes C. M. Schlachetzki, Danny Antaki, Addison J. Lana, Xin Xu, Changuk Chung, Guoliang Chai, Valentina Stanley, Qiong Song, Traci Fang Newmeyer, An T. Nguyen, S O'Brien, Marten A. Hoeksema, Beibei Cao, Alexi Nott, Jennifer McEvoy‐Venneri, Martina P. Pasillas, Scott T. Barton, Brett Copeland, Shareef Nahas, Lucitia Van Der Kraan, Yan Ding, Joseph G. Gleeson, Martin W. Breuss, Xiaoxu Yang, Danny Antaki, Changuk Chung, Dan Averbuj, Eric Courchesne, Laurel Ball, Subhojit Roy, Daniel R. Weinberger, Andrew E. Jaffe, Apuã C.M. Paquola, Jennifer A. Erwin, Jooheon Shin, Michael J. McConnell, Richard E. Straub, Rujuta Narurkar, Gary W. Mathern, Christopher A. Walsh, Alice Lee, August Yue Huang, Alissa M. D’Gama, Caroline Dias, Eduardo A. Maury, Javier Ganz, Michael A. Lodato, Michael B. Miller, Pengpeng Li, Rachel E. Rodin, Rebeca Borges-Monroy, Robert Hill, Sara Bizzotto, Sattar Khoshkhoo, Sonia Kim, Zinan Zhou, Peter J. Park, Alison R. Barton, Alon Galor, Chong Chu, Craig L. Bohrson, D. Gulhan, Elaine T. Lim, Eun‐Cheon Lim, Giorgio Melloni, Isidro Cortes, Jake Lee, Joe Luquette, Lixing Yang, Maxwell A. Sherman, Michael E. Coulter, Min‐Seok Kwon, Semin Lee, Soo In Lee, Vinary Viswanadham, Yanmei Dou, Andrew Chess, Attila Jones, Chaggai Rosenbluh, Schahram Akbarian, Ben Langmead, Jeremy Thorpe, Sean Cho, Alexej Abyzov, Taejeong Bae, Yeongjun Jang, Yifan Wang, Cindy Molitor, Mette A. Peters, Fred H. Gage, Meiyan Wang, Patrick Reed, Sara B. Linker, Alexander E. Urban, Bo Zhou, Reenal Pattni, Xiaowei Zhu, Aitor Serres Amero

    Vydáno 2022
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  20. 20
    Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability

    Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability Autor Taejeong Bae, Liana Fasching, Yifan Wang, Joo Heon Shin, Milovan Šuvakov, Yeongjun Jang, Scott Norton, Caroline Dias, Jessica Mariani, Alexandre Jourdon, Feinan Wu, Arijit Panda, Reenal Pattni, Yasmine Chahine, Rebecca C. Yeh, Rosalinda C. Roberts, Anita Hüttner, Joel E. Kleinman, Thomas M. Hyde, Richard E. Straub, Christopher A. Walsh, Alexander E. Urban, James F. Leckman, Daniel R. Weinberger, Flora M. Vaccarino, Alexej Abyzov, Christopher A. Walsh, Peter J. Park, Nenad Šestan, Daniel R. Weinberger, John V. Moran, Fred H. Gage, Flora M. Vaccarino, Joseph G. Gleeson, Gary W. Mathern, Eric Courchesne, Subhojit Roy, Andrew Chess, Schahram Akbarian, Sara Bizzotto, Michael E. Coulter, Caroline Dias, Alissa M. D’Gama, Javier Ganz, Robert Hill, August Yue Huang, Sattar Khoshkhoo, Sonia Kim, Alice Lee, Michael A. Lodato, Eduardo A. Maury, Michael Miller, Rebeca Borges-Monroy, Rachel E. Rodin, Zinan Zhou, Craig L. Bohrson, Chong Chu, Isidro Cortés‐Ciriano, Yanmei Dou, Alon Galor, D. Gulhan, Min‐Seok Kwon, Joe Luquette, Maxwell A. Sherman, Vinay Viswanadham, Attila Jones, Chaggai Rosenbluh, Sean Cho, Ben Langmead, Jeremy Thorpe, Jennifer A. Erwin, Andrew E. Jaffe, Michael J. McConnell, Rujuta Narurkar, Apuã C.M. Paquola, Jooheon Shin, Richard E. Straub, Alexej Abyzov, Taejeong Bae, Yeongjun Jang, Yifan Wang, Cindy Molitor, Mette A. Peters, Sara B. Linker, Patrick Reed, Meiyan Wang, Alexander E. Urban, Bo Zhou, Xiaowei Zhu, Reenal Pattni, Aitor Serres Amero, David Juan, Irene Lobón, Tomàs Marquès‐Bonet, Manuel Solis Moruno, Raquel García Pérez, Inna Povolotskaya, Eduardo Soriano, Danny Antaki, Dan Averbuj

    Vydáno 2022
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