Search Results - Micah J. Niphakis

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  1. 1
    <i>O</i>-Hydroxyacetamide Carbamates as a Highly Potent and Selective Class of Endocannabinoid Hydrolase Inhibitors

    <i>O</i>-Hydroxyacetamide Carbamates as a Highly Potent and Selective Class of Endocannabinoid Hydrolase Inhibitors by Micah J. Niphakis, Douglas S. Johnson, T. Eric Ballard, Cory M. Stiff, Benjamin F. Cravatt

    Published 2011
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  2. 2
    Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells

    Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells by Jonathan J. Hulce, Armand B. Cognetta, Micah J. Niphakis, Sarah E. Tully, Benjamin F. Cravatt

    Published 2013
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  3. 3
    Attenuating ABHD17 isoforms augments the S-acylation and function of NOD2 and a subset of Crohn’s disease-associated NOD2 variants.

    Attenuating ABHD17 isoforms augments the S-acylation and function of NOD2 and a subset of Crohn’s disease-associated NOD2 variants. by Charneal L. Dixon, Noah R. Martin, Micah J. Niphakis, Benjamin F. Cravatt, Gregory D. Fairn

    Published 2025
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  4. 4
    Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases

    Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases by Armand B. Cognetta, Micah J. Niphakis, Hyeon‐Cheol Lee, Michael L. Martini, Jonathan J. Hulce, Benjamin F. Cravatt

    Published 2015
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  5. 5
    Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Antiwithdrawal Effects in Morphine-Dependent Mice

    Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Antiwithdrawal Effects in Morphine-Dependent Mice by Divya Ramesh, Thomas F. Gamage, Tim Vanuytsel, Robert A. Owens, Rehab A. Abdullah, Micah J. Niphakis, Terez Shea‐Donohue, Benjamin F. Cravatt, Aron H. Lichtman

    Published 2013
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  6. 6
    Evaluation of NHS Carbamates as a Potent and Selective Class of Endocannabinoid Hydrolase Inhibitors

    Evaluation of NHS Carbamates as a Potent and Selective Class of Endocannabinoid Hydrolase Inhibitors by Micah J. Niphakis, Armand B. Cognetta, Jae Won Chang, Matthew W. Buczynski, Loren H. Parsons, Frederika Byrne, James J. Burston, Victoria Chapman, Benjamin F. Cravatt

    Published 2013
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  7. 7
    Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice

    Selective Monoacylglycerol Lipase Inhibitors: Antinociceptive versus Cannabimimetic Effects in Mice by Bogna M. Ignatowska‐Jankowska, Jenny L. Wilkerson, Mohammed Ahmed Mustafa, Rehab A. Abdullah, Micah J. Niphakis, Jenny L. Wiley, Benjamin F. Cravatt, Aron H. Lichtman

    Published 2015
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  8. 8
    The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice

    The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice by Jenny L. Wilkerson, Sudeshna Ghosh, Mohammed Ahmed Mustafa, Rehab A. Abdullah, Micah J. Niphakis, Roberto Cabrera, Rafael L. Maldonado, Benjamin F. Cravatt, Aron H. Lichtman

    Published 2016
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  9. 9
    Highly Selective Inhibitors of Monoacylglycerol Lipase Bearing a Reactive Group that Is Bioisosteric with Endocannabinoid Substrates

    Highly Selective Inhibitors of Monoacylglycerol Lipase Bearing a Reactive Group that Is Bioisosteric with Endocannabinoid Substrates by Jae Won Chang, Micah J. Niphakis, Kenneth M. Lum, Armand B. Cognetta, Chu Wang, Megan L. Matthews, Sherry Niessen, Matthew W. Buczynski, Loren H. Parsons, Benjamin F. Cravatt

    Published 2012
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  10. 10
    A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells

    A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells by Micah J. Niphakis, Kenneth M. Lum, Armand B. Cognetta, Bruno E. Correia, Taka-Aki Ichu, José Olucha, Steven J Brown, Soumajit Kundu, Fabiana Piscitelli, Hugh Rosen, Benjamin F. Cravatt

    Published 2015
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  11. 11
    Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator

    Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator by Doğukan Mizrak, N. Sumru Bayın, Jinzhou Yuan, Zhouzerui Liu, Radu M. Suciu, Micah J. Niphakis, Nhi Ngo, Kenneth M. Lum, Benjamin F. Cravatt, Alexandra L. Joyner, Peter A. Sims

    Published 2020
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  12. 12
    Endocannabinoid regulation of nausea is mediated by 2-arachidonoylglycerol (2-AG) in the rat visceral insular cortex

    Endocannabinoid regulation of nausea is mediated by 2-arachidonoylglycerol (2-AG) in the rat visceral insular cortex by Martin A. Sticht, Cheryl L. Limebeer, Benjamin R. Rafla, Rehab A. Abdullah, Justin L. Poklis, Winnie Ho, Micah J. Niphakis, Benjamin F. Cravatt, Keith A. Sharkey, Aron H. Lichtman, Linda A. Parker

    Published 2015
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  13. 13
    <i>In vivo</i> characterization of the highly selective monoacylglycerol lipase inhibitor <scp>KML</scp>29: antinociceptive activity without cannabimimetic side effects

    <i>In vivo</i> characterization of the highly selective monoacylglycerol lipase inhibitor <scp>KML</scp>29: antinociceptive activity without cannabimimetic side effects by Bogna M. Ignatowska‐Jankowska, Sudeshna Ghosh, Molly S. Crowe, Steven G. Kinsey, Micah J. Niphakis, Rehab A. Abdullah, Tao Qing, S T O' Neal, D. Matthew Walentiny, Jenny L. Wiley, Benjamin F. Cravatt, Aron H. Lichtman

    Published 2013
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  14. 14
    The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model

    The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model by Jenny L. Wilkerson, Micah J. Niphakis, Travis W. Grim, Maysoun A. Mustafa, Rehab A. Abdullah, Justin L. Poklis, William L. Dewey, Hamid I. Akbarali, Matthew L. Banks, Laura E. Wise, Benjamin F. Cravatt, Aron H. Lichtman

    Published 2016
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  15. 15
    Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy

    Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy by Zachary A. Curry, Jenny L. Wilkerson, Deniz Bağdaş, S. Lauren Kyte, Nipa Patel, Giulia Donvito, Mohammed Ahmed Mustafa, Justin L. Poklis, Micah J. Niphakis, Ku‐Lung Hsu, Benjamin F. Cravatt, David A. Gewirtz, M. Imad Damaj, Aron H. Lichtman

    Published 2018
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  16. 16
    Inflammation causes insulin resistance in mice via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels

    Inflammation causes insulin resistance in mice via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels by Shuai Yan, Anna Santoro, Micah J. Niphakis, Antônio F. M. Pinto, Christopher Jacobs, Rasheed Ahmad, Radu M. Suciu, Bryan R. Fonslow, Rachel A. Herbst-Graham, Nhi Ngo, Cassandra L. Henry, Dylan M. Herbst, Alan Saghatelian, Barbara B. Kahn, Evan D. Rosen

    Published 2024
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  17. 17
    Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling

    Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling by Alán Alpár, Giuseppe Tortoriello, Daniela Calvigioni, Micah J. Niphakis, Ivan Milenković, Joanne Bakker, Gary A. Cameron, János Hanics, Claudia V. Morris, János Fuzik, Gábor G. Kovács, Benjamin F. Cravatt, John G. Parnavelas, William D. Andrews, Yasmin L. Hurd, Erik Keimpema, Tibor Harkany

    Published 2014
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  18. 18
    AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice

    AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice by Meric Erikci Ertunc, Bernard P. Kok, William H. Parsons, Justin Wang, Dan Tan, Cynthia J. Donaldson, Antônio F. M. Pinto, Joan Vaughan, Nhi Ngo, Kenneth M. Lum, Cassandra L. Henry, Aundrea R. Coppola, Micah J. Niphakis, Benjamin F. Cravatt, Enrique Sáez, Alan Saghatelian

    Published 2020
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  19. 19
    Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron

    Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron by Laura J. Keller, Taylor H. Nguyen, Lawrence J. Liu, Brianna M. Hurysz, Markus Lakemeyer, Matteo Guerra, Danielle J. Gelsinger, Rachael B. Chanin, Nhi Ngo, Kenneth M. Lum, Franco Faucher, Phillip Ipock, Micah J. Niphakis, Ami S. Bhatt, Anthony J. O’Donoghue, Kerwyn Casey Huang, Matthew Bogyo

    Published 2023
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  20. 20
    ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth

    ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth by Jarrett R. Remsberg, Radu M. Suciu, Noemi A. Zambetti, Thomas W. Hanigan, Ari Firestone, Anagha Inguva, Amanda M. Long, Nhi Ngo, Kenneth M. Lum, Cassandra L. Henry, Stewart K. Richardson, Marina Predovic, Benjamin J. Huang, Melissa M. Dix, Amy R. Howell, Micah J. Niphakis, Kevin Shannon, Benjamin F. Cravatt

    Published 2021
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