檢索結果 - Merchant, Kalpana

Developing Therapeutics for Schizophrenia and Other Psychotic Disorders 由 Marek, Gerard, Merchant, Kalpana

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Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders 由 Schadt, Eric E., Buchanan, Sean, Brennand, Kristen J., Merchant, Kalpana M.

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LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson’s disease patients 由 Ysselstein, Daniel, Nguyen, Maria, Young, Tiffany J., Severino, Alex, Schwake, Michael, Merchant, Kalpana, Krainc, Dimitri

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Urinary proteome profiling for stratifying patients with familial Parkinson’s disease 由 Virreira Winter, Sebastian, Karayel, Ozge, Strauss, Maximilian T, Padmanabhan, Shalini, Surface, Matthew, Merchant, Kalpana, Alcalay, Roy N, Mann, Matthias

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Higher Urine bis(Monoacylglycerol)Phosphate Levels in LRRK2 G2019S Mutation Carriers: Implications for Therapeutic Development 由 Alcalay, Roy N., Hsieh, Frank, Tengstrand, Elizabeth, Padmanabhan, Shalini, Baptista, Marco, Kehoe, Caitlin, Narayan, Sushma, Boehme, Amelia K., Merchant, Kalpana

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Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry 由 Kellie, John F., Higgs, Richard E., Ryder, John W., Major, Anthony, Beach, Thomas G., Adler, Charles H., Merchant, Kalpana, Knierman, Michael D.

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Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson’s disease 由 Karayel, Ozge, Virreira Winter, Sebastian, Padmanabhan, Shalini, Kuras, Yuliya I., Vu, Duc Tung, Tuncali, Idil, Merchant, Kalpana, Wills, Anne-Marie, Scherzer, Clemens R., Mann, Matthias

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Plasma Glucosylsphingosine in GBA1 Mutation Carriers with and without Parkinson's Disease 由 Surface, Matthew, Balwani, Manisha, Waters, Cheryl, Haimovich, Alexander, Gan‐Or, Ziv, Marder, Karen S., Hsieh, Tammy, Song, Linxia, Padmanabhan, Shalini, Hsieh, Frank, Merchant, Kalpana M., Alcalay, Roy N.

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The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites 由 Greggio, Elisa, Taymans, Jean-Marc, Zhen, Eugene Yuejun, Ryder, John, Vancraenenbroeck, Renée, Beilina, Alexandra, Sun, Peng, Deng, Junpeng, Jaffe, Howard, Baekelandt, Veerle, Merchant, Kalpana, Cookson, Mark R.

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Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression 由 Concha‐Marambio, Luis, Farris, Carly M., Holguin, Bret, Ma, Yihua, Seibyl, John, Russo, Marco J., Kang, Un J., Hutten, Samantha J., Merchant, Kalpana, Shahnawaz, Mohammad, Soto, Claudio

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Translating Glutamate: From Pathophysiology to Treatment 由 Javitt, Daniel C., Schoepp, Darryle, Kalivas, Peter W., Volkow, Nora D., Zarate, Carlos, Merchant, Kalpana, Bear, Mark F., Umbricht, Daniel, Hajos, Mihaly, Potter, William Z., Lee, Chi-Ming

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Targeting α-synuclein for treating Parkinson’s disease: mechanistic and therapeutic considerations 由 Dehay, Benjamin, Bourdenx, Mathieu, Gorry, Philippe, Przedborski, Serge, Vila, Miquel, Hunot, Stephane, Singleton, Andrew, Olanow, C. Warren, Merchant, Kalpana M., Bezard, Erwan, Petsko, Gregory A., Meissner, Wassilios G.

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Gain and loss of function of P2X(7) receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain 由 Ursu, Daniel, Ebert, Philip, Langron, Emily, Ruble, Cara, Munsie, Leanne, Zou, Wei, Fijal, Bonnie, Qian, Yue-Wei, McNearney, Terry A, Mogg, Adrian, Grubisha, Olivera, Merchant, Kalpana, Sher, Emanuele

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Biochemical and Morphological Consequences of Human α-Synuclein Expression in a Mouse α-Synuclein Null Background 由 Prasad, Kavita, Tarasewicz, Elizabeth, Strickland, Pamela A. Ohman, O’Neill, Michael, Mitchell, Stephen N., Merchant, Kalpana, Tep, Samnang, Hilton, Kathryn, Datwani, Akash, Buttini, Manuel, Mueller-Steiner, Sarah, Richfield, Eric K.

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Biomarkers for the Development of New Medications for Cocaine Dependence 由 Bough, Kristopher J, Amur, Shashi, Lao, Guifang, Hemby, Scott E, Tannu, Nilesh S, Kampman, Kyle M, Schmitz, Joy M, Martinez, Diana, Merchant, Kalpana M, Green, Charles, Sharma, Jyoti, Dougherty, Anne H, Moeller, F Gerard

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A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein 由 Merchant, Kalpana M., Cedarbaum, Jesse M., Brundin, Patrik, Dave, Kuldip D., Eberling, Jamie, Espay, Alberto J., Hutten, Samantha J., Javidnia, Monica, Luthman, Johan, Maetzler, Walter, Menalled, Liliana, Reimer, Alyssa N., Stoessl, A. Jon, Weiner, David M.

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An Assessment of LRRK2 Serine 935 Phosphorylation in Human Peripheral Blood Mononuclear Cells in Idiopathic Parkinson’s Disease and G2019S LRRK2 Cohorts 由 Padmanabhan, Shalini, Lanz, Thomas A., Gorman, Donal, Wolfe, Michele, Joyce, Alison, Cabrera, Carlos, Lawrence-Henderson, Rosemary, Levers, Najah, Joshi, Neal, Ma, Thong C., Liong, Christopher, Narayan, Sushma, Alcalay, Roy N., Hutten, Samantha J., Baptista, Marco A.S., Merchant, Kalpana

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A user's guide for α‐synuclein biomarker studies in biological fluids: Perianalytical considerations 由 Mollenhauer, Brit, Batrla, Richard, El‐Agnaf, Omar, Galasko, Douglas R., Lashuel, Hilal A., Merchant, Kalpana M., Shaw, Lesley M., Selkoe, Dennis J., Umek, Robert, Vanderstichele, Hugo, Zetterberg, Henrik, Zhang, Jing, Caspell‐Garcia, Chelsea, Coffey, Chris, Hutten, Samantha J., Frasier, Mark, Taylor, Peggy

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Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial 由 Simuni, Tanya, Fiske, Brian, Merchant, Kalpana, Coffey, Christopher S., Klingner, Elizabeth, Caspell-Garcia, Chelsea, Lafontant, David-Erick, Matthews, Helen, Wyse, Richard K., Brundin, Patrik, Simon, David K., Schwarzschild, Michael, Weiner, David, Adams, Jamie, Venuto, Charles, Dawson, Ted M., Baker, Liana, Kostrzebski, Melissa, Ward, Tina, Rafaloff, Gary

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Longitudinal Measurements of Glucocerebrosidase activity in Parkinson’s patients 由 Alcalay, Roy N., Wolf, Pavlina, Chiang, Ming Sum Ruby, Helesicova, Karolina, Zhang, Xiaokui Kate, Merchant, Kalpana, Hutten, Samantha J., Scherzer, Clemens, Caspell‐Garcia, Chelsea, Blauwendraat, Cornelis, Foroud, Tatiana, Nudelman, Kelly, Gan‐Or, Ziv, Simuni, Tanya, Chahine, Lana M., Levy, Oren, Zheng, Dandi, Li, Gen, Sardi, Sergio Pablo

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