Risultati della ricerca - Merchant, Kalpana

Developing Therapeutics for Schizophrenia and Other Psychotic Disorders di Marek, Gerard, Merchant, Kalpana

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Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders di Schadt, Eric E., Buchanan, Sean, Brennand, Kristen J., Merchant, Kalpana M.

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LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson’s disease patients di Ysselstein, Daniel, Nguyen, Maria, Young, Tiffany J., Severino, Alex, Schwake, Michael, Merchant, Kalpana, Krainc, Dimitri

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Urinary proteome profiling for stratifying patients with familial Parkinson’s disease di Virreira Winter, Sebastian, Karayel, Ozge, Strauss, Maximilian T, Padmanabhan, Shalini, Surface, Matthew, Merchant, Kalpana, Alcalay, Roy N, Mann, Matthias

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Higher Urine bis(Monoacylglycerol)Phosphate Levels in LRRK2 G2019S Mutation Carriers: Implications for Therapeutic Development di Alcalay, Roy N., Hsieh, Frank, Tengstrand, Elizabeth, Padmanabhan, Shalini, Baptista, Marco, Kehoe, Caitlin, Narayan, Sushma, Boehme, Amelia K., Merchant, Kalpana

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Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry di Kellie, John F., Higgs, Richard E., Ryder, John W., Major, Anthony, Beach, Thomas G., Adler, Charles H., Merchant, Kalpana, Knierman, Michael D.

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Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson’s disease di Karayel, Ozge, Virreira Winter, Sebastian, Padmanabhan, Shalini, Kuras, Yuliya I., Vu, Duc Tung, Tuncali, Idil, Merchant, Kalpana, Wills, Anne-Marie, Scherzer, Clemens R., Mann, Matthias

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Plasma Glucosylsphingosine in GBA1 Mutation Carriers with and without Parkinson's Disease di Surface, Matthew, Balwani, Manisha, Waters, Cheryl, Haimovich, Alexander, Gan‐Or, Ziv, Marder, Karen S., Hsieh, Tammy, Song, Linxia, Padmanabhan, Shalini, Hsieh, Frank, Merchant, Kalpana M., Alcalay, Roy N.

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The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites di Greggio, Elisa, Taymans, Jean-Marc, Zhen, Eugene Yuejun, Ryder, John, Vancraenenbroeck, Renée, Beilina, Alexandra, Sun, Peng, Deng, Junpeng, Jaffe, Howard, Baekelandt, Veerle, Merchant, Kalpana, Cookson, Mark R.

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Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression di Concha‐Marambio, Luis, Farris, Carly M., Holguin, Bret, Ma, Yihua, Seibyl, John, Russo, Marco J., Kang, Un J., Hutten, Samantha J., Merchant, Kalpana, Shahnawaz, Mohammad, Soto, Claudio

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Translating Glutamate: From Pathophysiology to Treatment di Javitt, Daniel C., Schoepp, Darryle, Kalivas, Peter W., Volkow, Nora D., Zarate, Carlos, Merchant, Kalpana, Bear, Mark F., Umbricht, Daniel, Hajos, Mihaly, Potter, William Z., Lee, Chi-Ming

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Targeting α-synuclein for treating Parkinson’s disease: mechanistic and therapeutic considerations di Dehay, Benjamin, Bourdenx, Mathieu, Gorry, Philippe, Przedborski, Serge, Vila, Miquel, Hunot, Stephane, Singleton, Andrew, Olanow, C. Warren, Merchant, Kalpana M., Bezard, Erwan, Petsko, Gregory A., Meissner, Wassilios G.

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Gain and loss of function of P2X(7) receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain di Ursu, Daniel, Ebert, Philip, Langron, Emily, Ruble, Cara, Munsie, Leanne, Zou, Wei, Fijal, Bonnie, Qian, Yue-Wei, McNearney, Terry A, Mogg, Adrian, Grubisha, Olivera, Merchant, Kalpana, Sher, Emanuele

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Biochemical and Morphological Consequences of Human α-Synuclein Expression in a Mouse α-Synuclein Null Background di Prasad, Kavita, Tarasewicz, Elizabeth, Strickland, Pamela A. Ohman, O’Neill, Michael, Mitchell, Stephen N., Merchant, Kalpana, Tep, Samnang, Hilton, Kathryn, Datwani, Akash, Buttini, Manuel, Mueller-Steiner, Sarah, Richfield, Eric K.

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Biomarkers for the Development of New Medications for Cocaine Dependence di Bough, Kristopher J, Amur, Shashi, Lao, Guifang, Hemby, Scott E, Tannu, Nilesh S, Kampman, Kyle M, Schmitz, Joy M, Martinez, Diana, Merchant, Kalpana M, Green, Charles, Sharma, Jyoti, Dougherty, Anne H, Moeller, F Gerard

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A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein di Merchant, Kalpana M., Cedarbaum, Jesse M., Brundin, Patrik, Dave, Kuldip D., Eberling, Jamie, Espay, Alberto J., Hutten, Samantha J., Javidnia, Monica, Luthman, Johan, Maetzler, Walter, Menalled, Liliana, Reimer, Alyssa N., Stoessl, A. Jon, Weiner, David M.

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An Assessment of LRRK2 Serine 935 Phosphorylation in Human Peripheral Blood Mononuclear Cells in Idiopathic Parkinson’s Disease and G2019S LRRK2 Cohorts di Padmanabhan, Shalini, Lanz, Thomas A., Gorman, Donal, Wolfe, Michele, Joyce, Alison, Cabrera, Carlos, Lawrence-Henderson, Rosemary, Levers, Najah, Joshi, Neal, Ma, Thong C., Liong, Christopher, Narayan, Sushma, Alcalay, Roy N., Hutten, Samantha J., Baptista, Marco A.S., Merchant, Kalpana

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A user's guide for α‐synuclein biomarker studies in biological fluids: Perianalytical considerations di Mollenhauer, Brit, Batrla, Richard, El‐Agnaf, Omar, Galasko, Douglas R., Lashuel, Hilal A., Merchant, Kalpana M., Shaw, Lesley M., Selkoe, Dennis J., Umek, Robert, Vanderstichele, Hugo, Zetterberg, Henrik, Zhang, Jing, Caspell‐Garcia, Chelsea, Coffey, Chris, Hutten, Samantha J., Frasier, Mark, Taylor, Peggy

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Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial di Simuni, Tanya, Fiske, Brian, Merchant, Kalpana, Coffey, Christopher S., Klingner, Elizabeth, Caspell-Garcia, Chelsea, Lafontant, David-Erick, Matthews, Helen, Wyse, Richard K., Brundin, Patrik, Simon, David K., Schwarzschild, Michael, Weiner, David, Adams, Jamie, Venuto, Charles, Dawson, Ted M., Baker, Liana, Kostrzebski, Melissa, Ward, Tina, Rafaloff, Gary

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Longitudinal Measurements of Glucocerebrosidase activity in Parkinson’s patients di Alcalay, Roy N., Wolf, Pavlina, Chiang, Ming Sum Ruby, Helesicova, Karolina, Zhang, Xiaokui Kate, Merchant, Kalpana, Hutten, Samantha J., Scherzer, Clemens, Caspell‐Garcia, Chelsea, Blauwendraat, Cornelis, Foroud, Tatiana, Nudelman, Kelly, Gan‐Or, Ziv, Simuni, Tanya, Chahine, Lana M., Levy, Oren, Zheng, Dandi, Li, Gen, Sardi, Sergio Pablo

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