Suchergebnisse - Merchant, Kalpana

Developing Therapeutics for Schizophrenia and Other Psychotic Disorders von Marek, Gerard, Merchant, Kalpana

Volltext Volltext

Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders von Schadt, Eric E., Buchanan, Sean, Brennand, Kristen J., Merchant, Kalpana M.

Volltext Volltext Volltext

LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson’s disease patients von Ysselstein, Daniel, Nguyen, Maria, Young, Tiffany J., Severino, Alex, Schwake, Michael, Merchant, Kalpana, Krainc, Dimitri

Volltext Volltext Volltext

Urinary proteome profiling for stratifying patients with familial Parkinson’s disease von Virreira Winter, Sebastian, Karayel, Ozge, Strauss, Maximilian T, Padmanabhan, Shalini, Surface, Matthew, Merchant, Kalpana, Alcalay, Roy N, Mann, Matthias

Volltext Volltext Volltext

Higher Urine bis(Monoacylglycerol)Phosphate Levels in LRRK2 G2019S Mutation Carriers: Implications for Therapeutic Development von Alcalay, Roy N., Hsieh, Frank, Tengstrand, Elizabeth, Padmanabhan, Shalini, Baptista, Marco, Kehoe, Caitlin, Narayan, Sushma, Boehme, Amelia K., Merchant, Kalpana

Volltext Volltext Volltext

Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry von Kellie, John F., Higgs, Richard E., Ryder, John W., Major, Anthony, Beach, Thomas G., Adler, Charles H., Merchant, Kalpana, Knierman, Michael D.

Volltext Volltext Volltext

Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson’s disease von Karayel, Ozge, Virreira Winter, Sebastian, Padmanabhan, Shalini, Kuras, Yuliya I., Vu, Duc Tung, Tuncali, Idil, Merchant, Kalpana, Wills, Anne-Marie, Scherzer, Clemens R., Mann, Matthias

Volltext Volltext Volltext

Plasma Glucosylsphingosine in GBA1 Mutation Carriers with and without Parkinson's Disease von Surface, Matthew, Balwani, Manisha, Waters, Cheryl, Haimovich, Alexander, Gan‐Or, Ziv, Marder, Karen S., Hsieh, Tammy, Song, Linxia, Padmanabhan, Shalini, Hsieh, Frank, Merchant, Kalpana M., Alcalay, Roy N.

Volltext Volltext Volltext

The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites von Greggio, Elisa, Taymans, Jean-Marc, Zhen, Eugene Yuejun, Ryder, John, Vancraenenbroeck, Renée, Beilina, Alexandra, Sun, Peng, Deng, Junpeng, Jaffe, Howard, Baekelandt, Veerle, Merchant, Kalpana, Cookson, Mark R.

Volltext Volltext Volltext

Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression von Concha‐Marambio, Luis, Farris, Carly M., Holguin, Bret, Ma, Yihua, Seibyl, John, Russo, Marco J., Kang, Un J., Hutten, Samantha J., Merchant, Kalpana, Shahnawaz, Mohammad, Soto, Claudio

Volltext Volltext Volltext

Translating Glutamate: From Pathophysiology to Treatment von Javitt, Daniel C., Schoepp, Darryle, Kalivas, Peter W., Volkow, Nora D., Zarate, Carlos, Merchant, Kalpana, Bear, Mark F., Umbricht, Daniel, Hajos, Mihaly, Potter, William Z., Lee, Chi-Ming

Volltext Volltext Volltext

Targeting α-synuclein for treating Parkinson’s disease: mechanistic and therapeutic considerations von Dehay, Benjamin, Bourdenx, Mathieu, Gorry, Philippe, Przedborski, Serge, Vila, Miquel, Hunot, Stephane, Singleton, Andrew, Olanow, C. Warren, Merchant, Kalpana M., Bezard, Erwan, Petsko, Gregory A., Meissner, Wassilios G.

Volltext Volltext Volltext

Gain and loss of function of P2X(7) receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain von Ursu, Daniel, Ebert, Philip, Langron, Emily, Ruble, Cara, Munsie, Leanne, Zou, Wei, Fijal, Bonnie, Qian, Yue-Wei, McNearney, Terry A, Mogg, Adrian, Grubisha, Olivera, Merchant, Kalpana, Sher, Emanuele

Volltext Volltext Volltext

Biochemical and Morphological Consequences of Human α-Synuclein Expression in a Mouse α-Synuclein Null Background von Prasad, Kavita, Tarasewicz, Elizabeth, Strickland, Pamela A. Ohman, O’Neill, Michael, Mitchell, Stephen N., Merchant, Kalpana, Tep, Samnang, Hilton, Kathryn, Datwani, Akash, Buttini, Manuel, Mueller-Steiner, Sarah, Richfield, Eric K.

Volltext Volltext Volltext

Biomarkers for the Development of New Medications for Cocaine Dependence von Bough, Kristopher J, Amur, Shashi, Lao, Guifang, Hemby, Scott E, Tannu, Nilesh S, Kampman, Kyle M, Schmitz, Joy M, Martinez, Diana, Merchant, Kalpana M, Green, Charles, Sharma, Jyoti, Dougherty, Anne H, Moeller, F Gerard

Volltext Volltext Volltext

A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein von Merchant, Kalpana M., Cedarbaum, Jesse M., Brundin, Patrik, Dave, Kuldip D., Eberling, Jamie, Espay, Alberto J., Hutten, Samantha J., Javidnia, Monica, Luthman, Johan, Maetzler, Walter, Menalled, Liliana, Reimer, Alyssa N., Stoessl, A. Jon, Weiner, David M.

Volltext Volltext Volltext

An Assessment of LRRK2 Serine 935 Phosphorylation in Human Peripheral Blood Mononuclear Cells in Idiopathic Parkinson’s Disease and G2019S LRRK2 Cohorts von Padmanabhan, Shalini, Lanz, Thomas A., Gorman, Donal, Wolfe, Michele, Joyce, Alison, Cabrera, Carlos, Lawrence-Henderson, Rosemary, Levers, Najah, Joshi, Neal, Ma, Thong C., Liong, Christopher, Narayan, Sushma, Alcalay, Roy N., Hutten, Samantha J., Baptista, Marco A.S., Merchant, Kalpana

Volltext Volltext Volltext

A user's guide for α‐synuclein biomarker studies in biological fluids: Perianalytical considerations von Mollenhauer, Brit, Batrla, Richard, El‐Agnaf, Omar, Galasko, Douglas R., Lashuel, Hilal A., Merchant, Kalpana M., Shaw, Lesley M., Selkoe, Dennis J., Umek, Robert, Vanderstichele, Hugo, Zetterberg, Henrik, Zhang, Jing, Caspell‐Garcia, Chelsea, Coffey, Chris, Hutten, Samantha J., Frasier, Mark, Taylor, Peggy

Volltext Volltext Volltext

Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial von Simuni, Tanya, Fiske, Brian, Merchant, Kalpana, Coffey, Christopher S., Klingner, Elizabeth, Caspell-Garcia, Chelsea, Lafontant, David-Erick, Matthews, Helen, Wyse, Richard K., Brundin, Patrik, Simon, David K., Schwarzschild, Michael, Weiner, David, Adams, Jamie, Venuto, Charles, Dawson, Ted M., Baker, Liana, Kostrzebski, Melissa, Ward, Tina, Rafaloff, Gary

Volltext Volltext Volltext

Longitudinal Measurements of Glucocerebrosidase activity in Parkinson’s patients von Alcalay, Roy N., Wolf, Pavlina, Chiang, Ming Sum Ruby, Helesicova, Karolina, Zhang, Xiaokui Kate, Merchant, Kalpana, Hutten, Samantha J., Scherzer, Clemens, Caspell‐Garcia, Chelsea, Blauwendraat, Cornelis, Foroud, Tatiana, Nudelman, Kelly, Gan‐Or, Ziv, Simuni, Tanya, Chahine, Lana M., Levy, Oren, Zheng, Dandi, Li, Gen, Sardi, Sergio Pablo

Volltext Volltext Volltext