Resultats de la cerca - Merchant, Kalpana

Developing Therapeutics for Schizophrenia and Other Psychotic Disorders per Marek, Gerard, Merchant, Kalpana

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Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders per Schadt, Eric E., Buchanan, Sean, Brennand, Kristen J., Merchant, Kalpana M.

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LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson’s disease patients per Ysselstein, Daniel, Nguyen, Maria, Young, Tiffany J., Severino, Alex, Schwake, Michael, Merchant, Kalpana, Krainc, Dimitri

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Urinary proteome profiling for stratifying patients with familial Parkinson’s disease per Virreira Winter, Sebastian, Karayel, Ozge, Strauss, Maximilian T, Padmanabhan, Shalini, Surface, Matthew, Merchant, Kalpana, Alcalay, Roy N, Mann, Matthias

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Higher Urine bis(Monoacylglycerol)Phosphate Levels in LRRK2 G2019S Mutation Carriers: Implications for Therapeutic Development per Alcalay, Roy N., Hsieh, Frank, Tengstrand, Elizabeth, Padmanabhan, Shalini, Baptista, Marco, Kehoe, Caitlin, Narayan, Sushma, Boehme, Amelia K., Merchant, Kalpana

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Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry per Kellie, John F., Higgs, Richard E., Ryder, John W., Major, Anthony, Beach, Thomas G., Adler, Charles H., Merchant, Kalpana, Knierman, Michael D.

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Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson’s disease per Karayel, Ozge, Virreira Winter, Sebastian, Padmanabhan, Shalini, Kuras, Yuliya I., Vu, Duc Tung, Tuncali, Idil, Merchant, Kalpana, Wills, Anne-Marie, Scherzer, Clemens R., Mann, Matthias

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Plasma Glucosylsphingosine in GBA1 Mutation Carriers with and without Parkinson's Disease per Surface, Matthew, Balwani, Manisha, Waters, Cheryl, Haimovich, Alexander, Gan‐Or, Ziv, Marder, Karen S., Hsieh, Tammy, Song, Linxia, Padmanabhan, Shalini, Hsieh, Frank, Merchant, Kalpana M., Alcalay, Roy N.

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The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites per Greggio, Elisa, Taymans, Jean-Marc, Zhen, Eugene Yuejun, Ryder, John, Vancraenenbroeck, Renée, Beilina, Alexandra, Sun, Peng, Deng, Junpeng, Jaffe, Howard, Baekelandt, Veerle, Merchant, Kalpana, Cookson, Mark R.

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Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression per Concha‐Marambio, Luis, Farris, Carly M., Holguin, Bret, Ma, Yihua, Seibyl, John, Russo, Marco J., Kang, Un J., Hutten, Samantha J., Merchant, Kalpana, Shahnawaz, Mohammad, Soto, Claudio

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Translating Glutamate: From Pathophysiology to Treatment per Javitt, Daniel C., Schoepp, Darryle, Kalivas, Peter W., Volkow, Nora D., Zarate, Carlos, Merchant, Kalpana, Bear, Mark F., Umbricht, Daniel, Hajos, Mihaly, Potter, William Z., Lee, Chi-Ming

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Targeting α-synuclein for treating Parkinson’s disease: mechanistic and therapeutic considerations per Dehay, Benjamin, Bourdenx, Mathieu, Gorry, Philippe, Przedborski, Serge, Vila, Miquel, Hunot, Stephane, Singleton, Andrew, Olanow, C. Warren, Merchant, Kalpana M., Bezard, Erwan, Petsko, Gregory A., Meissner, Wassilios G.

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Gain and loss of function of P2X(7) receptors: mechanisms, pharmacology and relevance to diabetic neuropathic pain per Ursu, Daniel, Ebert, Philip, Langron, Emily, Ruble, Cara, Munsie, Leanne, Zou, Wei, Fijal, Bonnie, Qian, Yue-Wei, McNearney, Terry A, Mogg, Adrian, Grubisha, Olivera, Merchant, Kalpana, Sher, Emanuele

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Biochemical and Morphological Consequences of Human α-Synuclein Expression in a Mouse α-Synuclein Null Background per Prasad, Kavita, Tarasewicz, Elizabeth, Strickland, Pamela A. Ohman, O’Neill, Michael, Mitchell, Stephen N., Merchant, Kalpana, Tep, Samnang, Hilton, Kathryn, Datwani, Akash, Buttini, Manuel, Mueller-Steiner, Sarah, Richfield, Eric K.

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Biomarkers for the Development of New Medications for Cocaine Dependence per Bough, Kristopher J, Amur, Shashi, Lao, Guifang, Hemby, Scott E, Tannu, Nilesh S, Kampman, Kyle M, Schmitz, Joy M, Martinez, Diana, Merchant, Kalpana M, Green, Charles, Sharma, Jyoti, Dougherty, Anne H, Moeller, F Gerard

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A Proposed Roadmap for Parkinson’s Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein per Merchant, Kalpana M., Cedarbaum, Jesse M., Brundin, Patrik, Dave, Kuldip D., Eberling, Jamie, Espay, Alberto J., Hutten, Samantha J., Javidnia, Monica, Luthman, Johan, Maetzler, Walter, Menalled, Liliana, Reimer, Alyssa N., Stoessl, A. Jon, Weiner, David M.

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An Assessment of LRRK2 Serine 935 Phosphorylation in Human Peripheral Blood Mononuclear Cells in Idiopathic Parkinson’s Disease and G2019S LRRK2 Cohorts per Padmanabhan, Shalini, Lanz, Thomas A., Gorman, Donal, Wolfe, Michele, Joyce, Alison, Cabrera, Carlos, Lawrence-Henderson, Rosemary, Levers, Najah, Joshi, Neal, Ma, Thong C., Liong, Christopher, Narayan, Sushma, Alcalay, Roy N., Hutten, Samantha J., Baptista, Marco A.S., Merchant, Kalpana

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A user's guide for α‐synuclein biomarker studies in biological fluids: Perianalytical considerations per Mollenhauer, Brit, Batrla, Richard, El‐Agnaf, Omar, Galasko, Douglas R., Lashuel, Hilal A., Merchant, Kalpana M., Shaw, Lesley M., Selkoe, Dennis J., Umek, Robert, Vanderstichele, Hugo, Zetterberg, Henrik, Zhang, Jing, Caspell‐Garcia, Chelsea, Coffey, Chris, Hutten, Samantha J., Frasier, Mark, Taylor, Peggy

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Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial per Simuni, Tanya, Fiske, Brian, Merchant, Kalpana, Coffey, Christopher S., Klingner, Elizabeth, Caspell-Garcia, Chelsea, Lafontant, David-Erick, Matthews, Helen, Wyse, Richard K., Brundin, Patrik, Simon, David K., Schwarzschild, Michael, Weiner, David, Adams, Jamie, Venuto, Charles, Dawson, Ted M., Baker, Liana, Kostrzebski, Melissa, Ward, Tina, Rafaloff, Gary

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Longitudinal Measurements of Glucocerebrosidase activity in Parkinson’s patients per Alcalay, Roy N., Wolf, Pavlina, Chiang, Ming Sum Ruby, Helesicova, Karolina, Zhang, Xiaokui Kate, Merchant, Kalpana, Hutten, Samantha J., Scherzer, Clemens, Caspell‐Garcia, Chelsea, Blauwendraat, Cornelis, Foroud, Tatiana, Nudelman, Kelly, Gan‐Or, Ziv, Simuni, Tanya, Chahine, Lana M., Levy, Oren, Zheng, Dandi, Li, Gen, Sardi, Sergio Pablo

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