Search Results - Mei-Lin Okino
- Showing 1 - 8 results of 8
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Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral blood by Paola Benaglio, Jacklyn Newsome, Jee Yun Han, Joshua Chiou, Anthony Aylward, Sierra Corban, Michael Miller, Mei-Lin Okino, Jaspreet Kaur, Sebastian Preißl, David U. Gorkin, Kyle J. Gaulton
Published 2023Artigo -
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Interpreting type 1 diabetes risk with genetics and single-cell epigenomics by Joshua Chiou, Ryan J. Geusz, Mei-Lin Okino, Jee Yun Han, Michael Miller, Rebecca Melton, Elisha Beebe, Paola Benaglio, Serina Huang, Katha Korgaonkar, Sandra Heller, Alexander Kleger, Sebastian Preißl, David U. Gorkin, Maike Sander, Kyle J. Gaulton
Published 2021Artigo -
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Single-cell chromatin accessibility identifies pancreatic islet cell type– and state-specific regulatory programs of diabetes risk by Joshua Chiou, Chun Zeng, Cheng Zhang, Jee Yun Han, Michael Schlichting, Michael Miller, Robert Mendez, Serina Huang, Jinzhao Wang, Yinghui Sui, Allison Deogaygay, Mei-Lin Okino, Yunjiang Qiu, Ying Sun, Parul Kudtarkar, Rongxin Fang, Sebastian Preißl, Maike Sander, David U. Gorkin, Kyle J. Gaulton
Published 2021Artigo -
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Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk by William W. Greenwald, Joshua Chiou, Jian Yan, Yunjiang Qiu, Ning Dai, Allen Wang, Naoki Nariai, Anthony Aylward, Jee Yun Han, Nikita Kadakia, Laura Regué, Mei-Lin Okino, Frauke Drees, Dana Krämer, Nicholas K. Vinckier, Liliana Minichiello, David U. Gorkin, Joseph Avruch, Kelly A. Frazer, Maike Sander, Bing Ren, Kyle J. Gaulton
Published 2019Artigo -
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Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes by Gaowei Wang, Joshua Chiou, Chun Zeng, Michael Miller, Ileana Matta, Jee Yun Han, Nikita Kadakia, Mei-Lin Okino, Elisha Beebe, Medhavi Mallick, Joan Camuñas-Soler, Theodore dos Santos, Xiao-Qing Dai, Cara E. Ellis, Yan Hang, Seung K. Kim, Patrick E. MacDonald, Fouad Kandeel, Sebastian Preißl, Kyle J. Gaulton, Maike Sander
Published 2023Artigo
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Biology
Gene
Genetics
Endocrinology
Cell
Cell type
Gene expression
Chromatin
Computational biology
Islet
Diabetes mellitus
Beta cell
Enhancer
Genome-wide association study
Genotype
Insulin
Locus (genetics)
Pancreas
Single-nucleotide polymorphism
Type 1 diabetes
Type 2 diabetes
Allele
Cell biology
DNA methylation
Epigenomics
Medicine
Pancreatic islets
Transcription factor
Ductal cells
Endocrine system