Search Results - McClenaghan, Conor

Bridging Personal and Population in Excitability Diseases: Will Studies of Rare Diseases Bring Generalizable Mechanisms From Monogenic Channelopathies? by Nichols, Colin G, McClenaghan, Conor

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Pulmonary Hypertension and ATP-sensitive Potassium Channels: Paradigms and Paradoxes by McClenaghan, Conor, Woo, Kel Vin, Nichols, Colin G.

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Coronavirus Proteins as Ion Channels: Current and Potential Research by McClenaghan, Conor, Hanson, Alex, Lee, Sun-Joo, Nichols, Colin G.

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Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel by Cooper, Paige E., McClenaghan, Conor, Chen, Xingyu, Stary-Weinzinger, Anna, Nichols, Colin G.

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Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states by McClenaghan, Conor, Schewe, Marcus, Aryal, Prafulla, Carpenter, Elisabeth P., Baukrowitz, Thomas, Tucker, Stephen J.

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Cantu syndrome–associated SUR2 (ABCC9) mutations in distinct structural domains result in K(ATP) channel gain-of-function by differential mechanisms by McClenaghan, Conor, Hanson, Alex, Sala-Rabanal, Monica, Roessler, Helen I., Josifova, Dragana, Grange, Dorothy K., van Haaften, Gijs, Nichols, Colin G.

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Consequences of SUR2[A478V] Mutation in Skeletal Muscle of Murine Model of Cantu Syndrome by Scala, Rosa, Maqoud, Fatima, Zizzo, Nicola, Passantino, Giuseppe, Mele, Antonietta, Camerino, Giulia Maria, McClenaghan, Conor, Harter, Theresa M., Nichols, Colin G., Tricarico, Domenico

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Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by K(ATP) channel overactivity by McClenaghan, Conor, Huang, Yan, Yan, Zihan, Harter, Theresa M., Halabi, Carmen M., Chalk, Rod, Kovacs, Attila, van Haaften, Gijs, Remedi, Maria S., Nichols, Colin G.

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Pathophysiological Consequences of KATP Channel Overactivity and Pharmacological Response to Glibenclamide in Skeletal Muscle of a Murine Model of Cantù Syndrome by Scala, Rosa, Maqoud, Fatima, Zizzo, Nicola, Mele, Antonietta, Camerino, Giulia Maria, Zito, Francesco Alfredo, Ranieri, Girolamo, McClenaghan, Conor, Harter, Theresa M., Nichols, Colin G., Tricarico, Domenico

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The Mechanism of High-Output Cardiac Hypertrophy Arising From Potassium Channel Gain-of-Function in Cantú Syndrome by McClenaghan, Conor, Huang, Yan, Matkovich, Scot J, Kovacs, Attila, Weinheimer, Carla J, Perez, Ron, Broekelmann, Thomas J, Harter, Theresa M, Lee, Jin-Moo, Remedi, Maria S, Nichols, Colin G

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Cardiovascular consequences of K(ATP) overactivity in Cantu syndrome by Huang, Yan, McClenaghan, Conor, Harter, Theresa M., Hinman, Kristina, Halabi, Carmen M., Matkovich, Scot J., Zhang, Haixia, Brown, G. Schuyler, Mecham, Robert P., England, Sarah K., Kovacs, Attila, Remedi, Maria S., Nichols, Colin G.

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Sulfonylurea-insensitive permanent neonatal diabetes caused by a severe gain-of-function Tyr330His substitution in Kir6.2 by McClenaghan, Conor, Rapini, Novella, De Rose, Domenico Umberto, Gao, Jian, Roeglin, Jacob, Bizzarri, Carla, Schiaffini, Riccardo, Tiberi, Eloisa, Mucciolo, Mafalda, Deodati, Annalisa, Perri, Alessandro, Vento, Giovanni, Barbetti, Fabrizio, Nichols, Colin G., Cianfarani, Stefano

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Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel by Aryal, Prafulla, Jarerattanachat, Viwan, Clausen, Michael V., Schewe, Marcus, McClenaghan, Conor, Argent, Liam, Conrad, Linus J., Dong, Yin Y., Pike, Ashley C.W., Carpenter, Elisabeth P., Baukrowitz, Thomas, Sansom, Mark S.P., Tucker, Stephen J.

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Glibenclamide treatment in a Cantú syndrome patient with a pathogenic ABCC9 gain‐of‐function variant: Initial experience by Ma, Alan, Gurnasinghani, Sunita, Kirk, Edwin P., McClenaghan, Conor, Singh, Gautam K., Grange, Dorothy K., Pandit, Chetan, Zhu, Yung, Roscioli, Tony, Elakis, George, Buckley, Michael, Mehta, Bhavesh, Roberts, Philip, Mervis, Jonathan, Biggin, Andrew, Nichols, Colin G.

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Beta‐cell excitability and excitability‐driven diabetes in adult Zebrafish islets by Emfinger, Christopher H., Lőrincz, Réka, Wang, Yixi, York, Nathaniel W., Singareddy, Soma S., Ikle, Jennifer M., Tryon, Robert C., McClenaghan, Conor, Shyr, Zeenat A., Huang, Yan, Reissaus, Christopher A., Meyer, Dirk, Piston, David W., Hyrc, Krzysztof, Remedi, Maria S., Nichols, Colin G.

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Complex consequences of Cantu syndrome SUR2 variant R1154Q in genetically modified mice by Zhang, Haixia, Hanson, Alex, de Almeida, Tobias Scherf, Emfinger, Christopher, McClenaghan, Conor, Harter, Theresa, Yan, Zihan, Cooper, Paige E., Brown, G. Schuyler, Arakel, Eric C., Mecham, Robert P., Kovacs, Atilla, Halabi, Carmen M., Schwappach, Blanche, Remedi, Maria S., Nichols, Colin G.

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Cantú syndrome: Findings from 74 patients in the International Cantú Syndrome Registry by Grange, Dorothy K., Roessler, Helen I., McClenaghan, Conor, Duran, Karen, Shields, Kathleen, Remedi, Maria S., Knoers, Nine V. A. M., Lee, Jin-Moo, Kirk, Edwin P., Scurr, Ingrid, Smithson, Sarah F., Singh, Gautam K., van Haelst, Mieke M., Nichols, Colin G., van Haaften, Gijs

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K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac by Dong, Yin Yao, Pike, Ashley C.W., Mackenzie, Alexandra, McClenaghan, Conor, Aryal, Prafulla, Dong, Liang, Quigley, Andrew, Grieben, Mariana, Goubin, Solenne, Mukhopadhyay, Shubhashish, Ruda, Gian Filippo, Clausen, Michael V., Cao, Lishuang, Brennan, Paul E., Burgess-Brown, Nicola A., Sansom, Mark S. P., Tucker, Stephen J., Carpenter, Elisabeth P.

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ABCC9-related Intellectual disability Myopathy Syndrome is a K(ATP) channelopathy with loss-of-function mutations in ABCC9 by Smeland, Marie F., McClenaghan, Conor, Roessler, Helen I., Savelberg, Sanne, Hansen, Geir Åsmund Myge, Hjellnes, Helene, Arntzen, Kjell Arne, Müller, Kai Ivar, Dybesland, Andreas Rosenberger, Harter, Theresa, Sala-Rabanal, Monica, Emfinger, Chris H., Huang, Yan, Singareddy, Soma S., Gunn, Jamie, Wozniak, David F., Kovacs, Attila, Massink, Maarten, Tessadori, Federico, Kamel, Sarah M., Bakkers, Jeroen, Remedi, Maria S., Van Ghelue, Marijke, Nichols, Colin G., van Haaften, Gijs

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Loss of Function ABCC8 Mutations in Pulmonary Arterial Hypertension by Bohnen, Michael S., Ma, Lijiang, Zhu, Na, Qi, Hongjian, McClenaghan, Conor, Gonzaga-Jauregui, Claudia, Dewey, Frederick E., Overton, John D., Reid, Jeffrey G., Shuldiner, Alan R., Baras, Aris, Sampson, Kevin J., Bleda, Marta, Hadinnapola, Charaka, Haimel, Matthias, Bogaard, Harm J., Church, Colin, Coghlan, Gerry, Corris, Paul A., Eyries, Mélanie, Gibbs, J. Simon R., Girerd, Barbara, Houweling, Arjan C., Humbert, Marc, Guignabert, Christophe, Kiely, David G., Lawrie, Allan, MacKenzie Ross, Rob V., Martin, Jennifer M., Montani, David, Peacock, Andrew J., Pepke-Zaba, Joanna, Soubrier, Florent, Suntharalingam, Jay, Toshner, Mark, Treacy, Carmen M., Trembath, Richard C., Vonk Noordegraaf, Anton, Wharton, John, Wilkins, Martin R., Wort, Stephen J., Yates, Katherine, Gräf, Stefan, Morrell, Nicholas W., Krishnan, Usha, Rosenzweig, Erika B., Shen, Yufeng, Nichols, Colin G., Kass, Robert S., Chung, Wendy K.

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