Resultats de la cerca - Matthijs M. Jore

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  1. 1
    Targeting Bottlenecks in Malaria Transmission: Antibody‐Epitope Descriptions Guide the Design of Next‐Generation Biomedical Interventions

    Targeting Bottlenecks in Malaria Transmission: Antibody‐Epitope Descriptions Guide the Design of Next‐Generation Biomedical Interventions per Randy Yoo, Matthijs M. Jore, Jean‐Philippe Julien

    Publicat 2025
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  2. 2
    RNA in Defense: CRISPRs Protect Prokaryotes against Mobile Genetic Elements

    RNA in Defense: CRISPRs Protect Prokaryotes against Mobile Genetic Elements per Matthijs M. Jore, Stan J. J. Brouns, John van der Oost

    Publicat 2011
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  3. 3
    CRISPR-based adaptive and heritable immunity in prokaryotes

    CRISPR-based adaptive and heritable immunity in prokaryotes per John van der Oost, Matthijs M. Jore, Edze R. Westra, Magnus Lundgren, Stan J. J. Brouns

    Publicat 2009
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  4. 4
    Structural basis for therapeutic inhibition of complement C5

    Structural basis for therapeutic inhibition of complement C5 per Matthijs M. Jore, Steven Johnson, Devon Sheppard, Natalie M. Barber, Yang Li, Miles A. Nunn, Hans Elmlund, Susan M. Lea

    Publicat 2016
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  5. 5
    Immunity against sexual stage <i>Plasmodium falciparum</i> and <i>Plasmodium vivax</i> parasites

    Immunity against sexual stage <i>Plasmodium falciparum</i> and <i>Plasmodium vivax</i> parasites per Roos M. de Jong, Surafel K. Tebeje, Lisette Meerstein‐Kessel, Fitsum G. Tadesse, Matthijs M. Jore, William J. Stone, Teun Bousema

    Publicat 2019
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  6. 6
    Structures of the RNA-guided surveillance complex from a bacterial immune system

    Structures of the RNA-guided surveillance complex from a bacterial immune system per Blake Wiedenheft, Gabriel C. Lander, Kaihong Zhou, Matthijs M. Jore, Stan J. J. Brouns, John van der Oost, Jennifer A. Doudna, Eva Nogales

    Publicat 2011
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  7. 7
    Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies

    Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies per Kuang-Ting Ko, Frank Lennartz, David Mekhaiel, Bora Guloglu, Arianna Marini, Danielle Deuker, Carole A. Long, Matthijs M. Jore, Kazutoyo Miura, Sumi Biswas, Matthew K. Higgins

    Publicat 2022
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  8. 8
    Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

    Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence per Ekaterina Semenova, Matthijs M. Jore, Kirill A. Datsenko, А. В. Семенова, Edze R. Westra, Barry L. Wanner, John van der Oost, Stan J. J. Brouns, Konstantin Severinov

    Publicat 2011
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  9. 9
    Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45

    Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45 per Prasun Kundu, Anthony Semesi, Matthijs M. Jore, Merribeth J. Morin, V Price, Alice Liang, Jingxing Li, Kazutoyo Miura, Robert W. Sauerwein, C. Richter King, Jean‐Philippe Julien

    Publicat 2018
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  10. 10
    Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes

    Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes per Stan J. J. Brouns, Matthijs M. Jore, Magnus Lundgren, Edze R. Westra, Rik J. H. Slijkhuis, Ambrosius P. Snijders, Mark J. Dickman, Kira S. Makarova, Eugene V. Koonin, John van der Oost

    Publicat 2008
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  11. 11
    Native Tandem and Ion Mobility Mass Spectrometry Highlight Structural and Modular Similarities in Clustered-Regularly-Interspaced Shot-Palindromic-Repeats (CRISPR)-associated Protein Complexes From Escherichia coli and Pseudomonas aeruginosa

    Native Tandem and Ion Mobility Mass Spectrometry Highlight Structural and Modular Similarities in Clustered-Regularly-Interspaced Shot-Palindromic-Repeats (CRISPR)-associated Prote... per Esther van Duijn, Ioana Barbu, Arjan Barendregt, Matthijs M. Jore, Blake Wiedenheft, Magnus Lundgren, Edze R. Westra, Stan J. J. Brouns, Jennifer A. Doudna, John van der Oost, Albert J. R. Heck

    Publicat 2012
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  12. 12
    Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody

    Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody per Frank Lennartz, Florian Brod, Rebecca A. Dabbs, Kazutoyo Miura, David Mekhaiel, Arianna Marini, Matthijs M. Jore, Max Søgaard, Thomas R. Jørgensen, Willem A. de Jongh, Robert W. Sauerwein, Carole A. Long, Sumi Biswas, Matthew K. Higgins

    Publicat 2018
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  13. 13
    H‐NS‐mediated repression of CRISPR‐based immunity in <i>Escherichia coli</i> K12 can be relieved by the transcription activator LeuO

    H‐NS‐mediated repression of CRISPR‐based immunity in <i>Escherichia coli</i> K12 can be relieved by the transcription activator LeuO per Edze R. Westra, Ümit Pul, Nadja Heidrich, Matthijs M. Jore, Magnus Lundgren, Thomas Stratmann, Reinhild Wurm, Amanda Raine, Melina Mescher, Luc van Heereveld, Marieke Mastop, E. Gerhart H. Wagner, Karin Schnetz, John van der Oost, Rolf Wagner, Stan J. J. Brouns

    Publicat 2010
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  14. 14
    Pfs230 and Pfs48/45 Fusion Proteins Elicit Strong Transmission-Blocking Antibody Responses Against Plasmodium falciparum

    Pfs230 and Pfs48/45 Fusion Proteins Elicit Strong Transmission-Blocking Antibody Responses Against Plasmodium falciparum per Susheel Kumar Singh, Susan Thrane, Bishwanath Kumar Chourasia, Karina Teelen, Wouter Graumans, Rianne Stoter, Geert‐Jan van Gemert, Marga G. van de Vegte-Bolmer, Morten A. Nielsen, Ali Salanti, Adam F. Sander, Robert W. Sauerwein, Matthijs M. Jore, Michael Theisen

    Publicat 2019
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  15. 15
    CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

    CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3 per Edze R. Westra, Paul B. G. van Erp, Tim Künne, Shi Pey Wong, Raymond H.J. Staals, Christel L. C. Seegers, Sander Bollen, Matthijs M. Jore, Ekaterina Semenova, Konstantin Severinov, Willem M. de Vos, Remus T. Dame, Renko de Vries, Stan J. J. Brouns, John van der Oost

    Publicat 2012
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  16. 16
    A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial

    A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial per Mark J. Alkema, Martine J. Smit, Catherin Marin-Mogollon, K. Totté, Karina Teelen, Geert Jan van Gemert, Marga van de Vegte‐Bolmer, Benjamin Mordmüller, J. M. Reimer, K. Lövgren-Bengtsson, Robert W. Sauerwein, Teun Bousema, Jordan Plieskatt, Michael Theisen, Matthijs M. Jore, Matthew B. B. McCall

    Publicat 2024
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  17. 17
    Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross-stage recognition of glutamate-rich repeats

    Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross-stage recognition of glutamate-rich repeats per Axelle Amen, Randy Yoo, Amanda Fabra-García, Judith M. Bolscher, William J. Stone, Isabelle Bally, Sebastián Dergan‐Dylon, Iga Kucharska, Roos M. de Jong, Marloes de Bruijni, Teun Bousema, C. Richter King, Randall S. MacGill, Robert W. Sauerwein, Jean‐Philippe Julien, Pascal Poignard, Matthijs M. Jore

    Publicat 2025
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  18. 18
    Structural basis for CRISPR RNA-guided DNA recognition by Cascade

    Structural basis for CRISPR RNA-guided DNA recognition by Cascade per Matthijs M. Jore, Magnus Lundgren, Esther van Duijn, Jelle B. Bultema, Edze R. Westra, Sakharam Waghmare, Blake Wiedenheft, Ümit Pul, Reinhild Wurm, Rolf Wagner, Marieke R. Beijer, Arjan Barendregt, Kaihong Zhou, Ambrosius P. Snijders, Mark J. Dickman, Jennifer A. Doudna, Egbert J. Boekema, Albert J. R. Heck, John van der Oost, Stan J. J. Brouns

    Publicat 2011
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  19. 19
    Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies

    Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies per Ezra T. Bekkering, Randy Yoo, Sophia Hailemariam, Fabian Heide, Danton Ivanochko, Matthew R. Jackman, Nicholas I. Proellochs, Rianne Stoter, Jan C. van Gemert, Atsushi Maeda, Takaaki Yuguchi, Oscar T. Wanders, Renate C. van Daalen, Maartje R. Inklaar, Carolina M. Andrade, Pascal W.T.C. Jansen, Michiel Vermeulen, Teun Bousema, Eizo Takashima, John L. Rubinstein, Taco W. A. Kooij, Matthijs M. Jore, Jean‐Philippe Julien

    Publicat 2025
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  20. 20
    Safety, tolerability, and Plasmodium falciparum transmission-reducing activity of monoclonal antibody TB31F: a single-centre, open-label, first-in-human, dose-escalation, phase 1 trial in healthy malaria-naive adults

    Safety, tolerability, and Plasmodium falciparum transmission-reducing activity of monoclonal antibody TB31F: a single-centre, open-label, first-in-human, dose-escalation, phase 1 t... per Saskia C. van der Boor, Merel Smit, Stijn W. van Beek, Jordache Ramjith, Karina Teelen, Marga van de Vegte‐Bolmer, Geert‐Jan van Gemert, Peter Pickkers, Yimin Wu, Emily Locke, Shwu‐Maan Lee, John J. Aponte, C. Richter King, Ashley J. Birkett, Kazutoyo Miura, Morolayo A. Ayorinde, Robert W. Sauerwein, Rob ter Heine, Christian F. Ockenhouse, Teun Bousema, Matthijs M. Jore, Matthew B. B. McCall

    Publicat 2022
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