检索结果 - Matthias John
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Polyethylenimine/small interfering RNA‐mediated knockdown of vascular endothelial growth factor <i>in vivo</i> exerts anti‐tumor effects synergistically with Bevacizumab 由 Sabrina Höbel, Ivette Koburger, Matthias John, Frank Czubayko, Philipp Hadwiger, Hans‐Peter Vornlocher, Achim Aigner
出版 2010Artigo -
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Mouse Cytomegalovirus MicroRNAs Dominate the Cellular Small RNA Profile during Lytic Infection and Show Features of Posttranscriptional Regulation 由 Lars Dölken, Jonathan Perot, Valérie Cognat, Abdelmalek Alioua, Matthias John, Jürgen Soutschek, Zsolt Ruzsics, Ulrich H. Koszinowski, Olivier Voinnet, Sébastien Pfeffer
出版 2007Artigo -
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Chemical modifications on siRNAs avoid Toll-like-receptor-mediated activation of the hepatic immune system <i>in vivo</i> and <i>in vitro</i> 由 Ruth Broering, C.I. Real, Matthias John, Kerstin Jahn‐Hofmann, Ludger M. Ickenstein, K Kleinehr, Andreas Paul, Kathrin Gibbert, Ulf Dittmer, Guido Gerken, JF Schlaak
出版 2013Artigo -
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Unique Gene‐Silencing and Structural Properties of 2′‐Fluoro‐Modified siRNAs 由 Muthiah Manoharan, Akin Akinc, Rajendra K. Pandey, June Qin, Philipp Hadwiger, Matthias John, Kathy Mills, Klaus Charissé, Martin A. Maier, Lubomir V. Nechev, Emily M. Greene, Pradeep S. Pallan, Eriks Rozners, Kallanthottathil G. Rajeev, Martin Egli
出版 2011Artigo -
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Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway 由 Matthias John, Rainer Constien, Akin Akinc, Michael S. Goldberg, Young-Ah Moon, Martina Spranger, Philipp Hadwiger, Jürgen Soutschek, Hans-Peter Vornlocher, Muthiah Manoharan, Markus Stoffel, Róbert Langer, Daniel G. Anderson, Jay D. Horton, Victor Koteliansky, David Bumcrot
出版 2007Artigo -
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Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection 由 Christine I. Wooddell, David B. Rozema, Markus Hoßbach, Matthias John, Holly Hamilton, Qili Chu, Julia Hegge, Jason J. Klein, Darren H. Wakefield, Claudia E. Oropeza, Jochen Deckert, Ingo Roehl, Kerstin Jahn‐Hofmann, Philipp Hadwiger, Hans-Peter Vornlocher, A. McLachlan, David L. Lewis
出版 2013Artigo -
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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics 由 Akin Akinc, Andreas Zumbuehl, Michael S. Goldberg, Elizaveta S. Leshchiner, Valentina Busini, Naushad Hossain, Sergio Bacallado, David N. Nguyen, Jason Fuller, Rene Alvarez, Anna Borodovsky, Todd Borland, Rainer Constien, Antonin de Fougerolles, J. Robert Dorkin, K. N. Jayaprakash, Muthusamy Jayaraman, Matthias John, Victor Koteliansky, Muthiah Manoharan, Lubomir V. Nechev, June Qin, Timothy Racie, Denitza Raitcheva, Kallanthottathil G. Rajeev, Dinah W.Y. Sah, Jürgen Soutschek, Ivanka Toudjarska, Hans‐Peter Vornlocher, Tracy Zimmermann, Róbert Langer, Daniel G. Anderson
出版 2008Artigo -
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Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates 由 Maria Frank-Kamenetsky, Aldo Grefhorst, Norma N. Anderson, Timothy Racie, Birgit Bramlage, Akin Akinc, David Butler, Klaus Charissé, Robert Dorkin, Yupeng Fan, Christina Gamba‐Vitalo, Philipp Hadwiger, Muthusamy Jayaraman, Matthias John, K. N. Jayaprakash, Martin A. Maier, Lubomir V. Nechev, Kallanthottathil G. Rajeev, Timothy Read, Ingo Röhl, Jürgen Soutschek, Pamela Tan, Jamie Wong, Gang Wang, Tracy Zimmermann, Antonin de Fougerolles, Hans-Peter Vornlocher, Róbert Langer, Daniel G. Anderson, Muthiah Manoharan, Victor Koteliansky, Jay D. Horton, Kevin Fitzgerald
出版 2008Artigo
相关主题
Biology
Gene
RNA
Biochemistry
Genetics
Chemistry
RNA interference
Small interfering RNA
Cell biology
Immunology
Medicine
Molecular biology
Cell culture
Gene silencing
Transfection
Immune system
Internal medicine
microRNA
Biotechnology
COPD
Cancer research
Computational biology
Cytokine
Gene expression
Gene knockdown
In vitro
In vivo
Pharmacology
Small RNA
Tumor necrosis factor alpha