Výsledky vyhledávání - Martin Stogniew

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  1. 1
    In Vitro and In Vivo Studies To Characterize the Clearance Mechanism and Potential Cytochrome P450 Interactions of Anidulafungin

    In Vitro and In Vivo Studies To Characterize the Clearance Mechanism and Potential Cytochrome P450 Interactions of Anidulafungin Autor Bharat Damle, James A. Dowell, Robert L. Walsky, Gregory L. Weber, Martin Stogniew, Philip B. Inskeep

    Vydáno 2008
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    Artigo
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  2. 2
    Biological activity of weekly ONC201 in adult recurrent glioblastoma patients

    Biological activity of weekly ONC201 in adult recurrent glioblastoma patients Autor Isabel Arrillaga‐Romany, Yazmín Odia, Varun V. Prabhu, Rohinton S. Tarapore, Krystal Merdinger, Martin Stogniew, Wolfgang Oster, Joshua E. Allen, Minesh P. Mehta, Tracy T. Batchelor, Patrick Y. Wen

    Vydáno 2019
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    Artigo
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  3. 3
    Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212

    Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212 Autor Jessica Wagner, C. Leah B. Kline, Marie D. Ralff, Avital Lev, Amriti R. Lulla, Lanlan Zhou, Gary L. Olson, Bhaskara Rao Nallaganchu, Cyril H. Benes, Joshua E. Allen, Varun V. Prabhu, Martin Stogniew, Wolfgang Oster, Wafik S. El‐Deiry

    Vydáno 2017
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  4. 4
    Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia

    Imipridone ONC212 activates orphan G protein-coupled receptor GPR132 and integrated stress response in acute myeloid leukemia Autor Takenobu Nii, Varun V. Prabhu, Vivian Ruvolo, Neel S. Madhukar, Ran Zhao, Hong Mu, Lauren Heese, Yuki Nishida, Kensuke Kojima, Mathew J. Garnett, Ultan McDermott, Cyril H. Benes, Neil Charter, Sean Deacon, Olivier Elemento, Joshua E. Allen, Wolfgang Oster, Martin Stogniew, Jo Ishizawa, Michael Andreeff

    Vydáno 2019
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    Artigo
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  5. 5
    First-in-Human Clinical Trial of Oral ONC201 in Patients with Refractory Solid Tumors

    First-in-Human Clinical Trial of Oral ONC201 in Patients with Refractory Solid Tumors Autor Mark N. Stein, Joseph R. Bertino, Howard L. Kaufman, Tina Mayer, Rebecca A. Moss, Ann W. Silk, Nancy Chan, Jyoti Malhotra, Lorna Rodriguez, Joseph Aisner, Robert Aiken, Bruce G. Haffty, Robert S. DiPaola, Tracie Saunders, Andrew Zloza, Sherri Damare, Yasmeen Beckett, Bangning Yu, Saltanat Najmi, Christian Gabel, Siobhan Dickerson, Ling Zheng, Wafik S. El‐Deiry, Joshua E. Allen, Martin Stogniew, Wolfgang Oster, Janice M. Mehnert

    Vydáno 2017
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    Artigo
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  6. 6
    ONC201 and imipridones: Anti-cancer compounds with clinical efficacy

    ONC201 and imipridones: Anti-cancer compounds with clinical efficacy Autor Varun V. Prabhu, Sara Morrow, Abed Rahman Kawakibi, Lanlan Zhou, Marie D. Ralff, Jocelyn Ray, Aakash Jhaveri, Isacco Ferrarini, Young Lee, Cassandra Parker, Yiqun Zhang, Robyn Borsuk, Wen-I Chang, Joshua N. Honeyman, Fábio Távora, Benedito A. Carneiro, Alexander G. Raufi, Kelsey E. Huntington, Lindsey Carlsen, Anna D. Louie, Howard Safran, Attila A. Seyhan, Rohinton S. Tarapore, Lee Schalop, Martin Stogniew, Joshua E. Allen, Wolfgang Oster, Wafik S. El‐Deiry

    Vydáno 2020
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  7. 7
    Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201

    Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201 Autor S. Andrew, Rohinton S. Tarapore, Matthew D. Hall, Nicole Shonka, Sharon L. Gardner, Yoshie Umemura, Ashley Sumrall, Ziad Khatib, Sabine Mueller, Cassie Kline, Wafik Zaky, Soumen Khatua, Shiao-Pei Weathers, Yazmín Odia, Toba N. Niazi, Doured Daghistani, Irene Cherrick, David N. Korones, Matthias A. Karajannis, Xiao-Tang Kong, Jane E. Minturn, Angela J. Waanders, Isabel Arillaga-Romany, Tracy T. Batchelor, Patrick Y. Wen, Krystal Merdinger, Lee Schalop, Martin Stogniew, Joshua E. Allen, Wolfgang Oster, Minesh P. Mehta

    Vydáno 2019
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  8. 8
    Discovery and clinical introduction of first-in-class imipridone ONC201

    Discovery and clinical introduction of first-in-class imipridone ONC201 Autor Joshua E. Allen, C. Leah B. Kline, Varun V. Prabhu, Jessica Wagner, Jo Ishizawa, Neel S. Madhukar, Avital Lev, Marie Baumeister, Lanlan Zhou, Amriti R. Lulla, Martin Stogniew, Lee Schalop, Cyril H. Benes, Howard L. Kaufman, Richard S. Pottorf, Bhaskara Rao Nallaganchu, Gary L. Olson, Fahd Al‐Mulla, Madeleine Duvic, Gen Sheng Wu, David T. Dicker, Mala K. Talekar, Bora Lim, Olivier Elemento, Wolfgang Oster, Joseph Bertino, Keith T. Flaherty, Michael Wang, Gautam Borthakur, Michael Andreeff, Mark N. Stein, Wafik S. El‐Deiry

    Vydáno 2016
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  9. 9
    Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality

    Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality Autor Jo Ishizawa, Sarah F. Zarabi, R. Eric Davis, Ondrej Halgas, Takenobu Nii, Yulia Jitkova, Ran Zhao, Jonathan St‐Germain, Lauren Heese, Grace Egan, Vivian Ruvolo, Samir H. Barghout, Yuki Nishida, Rose Hurren, Wencai Ma, Marcela Gronda, Todd Link, Keith S. Wong, Mark Mabanglo, Kensuke Kojima, Gautam Borthakur, Neil MacLean, Man Chun John, Andrew B. Leber, Mark D. Minden, Walid A. Houry, Hagop M. Kantarjian, Martin Stogniew, Brian Raught, E.F. Pai, Aaron D. Schimmer, Michael Andreeff

    Vydáno 2019
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  10. 10
    Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration

    Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration Autor Mark N. Stein, Jyoti Malhotra, Rohinton S. Tarapore, Usha Malhotra, Ann W. Silk, Nancy Chan, Lorna Rodriguez, Joseph Aisner, Robert Aiken, Tina Mayer, Bruce G. Haffty, Jenna H. Newman, Salvatore Aspromonte, Praveen K. Bommareddy, Ricardo Estupinian, Charles B. Chesson, Evita Sadimin, Shengguo Li, Daniel Medina, Tracie Saunders, Melissa Frankel, Aparna Kareddula, Sherrie Damare, Elayne Wesolowsky, Christian Gabel, Wafik S. El‐Deiry, Varun V. Prabhu, Joshua E. Allen, Martin Stogniew, Wolfgang Oster, Joseph R. Bertino, Steven K. Libutti, Janice M. Mehnert, Andrew Zloza

    Vydáno 2019
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