Výsledky vyhledávání - Martin Scobie

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  1. 1
    Rational design and validation of a Tip60 histone acetyltransferase inhibitor

    Rational design and validation of a Tip60 histone acetyltransferase inhibitor Autor Chunxia Gao, Emer Bourke, Martin Scobie, Melina Arcos Famme, Tobias Koolmeister, Thomas Helleday, Leif A. Eriksson, Noel F. Lowndes, James A. L. Brown

    Vydáno 2014
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  2. 2
    Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

    Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities Autor Kumar Sanjiv, Anna Hagenkort, José Manuel Calderón‐Montaño, Tobias Koolmeister, Philip M. Reaper, Oliver Mortusewicz, Sylvain A. Jacques, Raoul Kuiper, Niklas Schultz, Martin Scobie, Peter Charlton, John R. Pollard, Ulrika Warpman Berglund, Mikael Altun, Thomas Helleday

    Vydáno 2015
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  3. 3
    Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

    Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities Autor Kumar Sanjiv, Anna Hagenkort, José Manuel Calderón‐Montaño, Tobias Koolmeister, Philip M. Reaper, Oliver Mortusewicz, Sylvain A. Jacques, Raoul Kuiper, Niklas Schultz, Martin Scobie, Peter Charlton, John R. Pollard, Ulrika Warpman Berglund, Mikael Altun, Thomas Helleday

    Vydáno 2016
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  4. 4
    A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma

    A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma Autor Berglind O. Einarsdottir, Joakim Karlsson, Elin Söderberg, Mattias F. Lindberg, Elisa Funck‐Brentano, Henrik Jespersen, Siggeir F. Brynjólfsson, Roger Olofsson Bagge, Louise Carstam, Martin Scobie, Tobias Koolmeister, Olov Wallner, Ulrika Stierner, Ulrika Warpman Berglund, Lars Ny, Lisa M. Nilsson, Erik Larsson, Thomas Helleday, Jonas A. Nilsson

    Vydáno 2018
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  5. 5
    Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

    Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells Autor Brent D. G. Page, Nicholas C.K. Valerie, Roni H. G. Wright, Olov Wallner, Rebecka Isaksson, Megan Carter, Sean G. Rudd, Olga Loseva, Ann‐Sofie Jemth, Ingrid Almlöf, Jofre Font-Mateu, Sabin Llona‐Minguez, Paweł Baranczewski, Fredrik Jeppsson, Evert Homan, Helena Almqvist, Hanna Axelsson, Shruti Regmi, Anna‐Lena Gustavsson, Thomas Lundbäck, Martin Scobie, Kia Strömberg, Pål Stenmark, Miguel Beato, Thomas Helleday

    Vydáno 2018
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  6. 6
    Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1

    Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1 Autor Sabin Llona‐Minguez, Andreas Höglund, Sylvain A. Jacques, Lars Johansson, José Manuel Calderón‐Montaño, Magnus Claesson, Olga Loseva, Nicholas C.K. Valerie, Thomas Lundbäck, Javier Piedrafita, Giovanni Maga, Emmanuele Crespan, Laurent Meijer, Estefanía Burgos‐Morón, Paweł Baranczewski, Ann-Louise Hagbjörk, Richard Svensson, Elisée Wiita, Ingrid Almlöf, Torkild Visnes, Fredrik Jeppsson, Kristmundur Sigmundsson, Annika Jenmalm Jensen, Per Artursson, Ann‐Sofie Jemth, Pål Stenmark, Ulrika Warpman Berglund, Martin Scobie, Thomas Helleday

    Vydáno 2016
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  7. 7
    Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

    Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation Autor Torkild Visnes, Armando Cázares‐Körner, Wenjing Hao, Olov Wallner, Geoffrey Masuyer, Olga Loseva, Oliver Mortusewicz, Elisée Wiita, Antonio Sarno, Aleksandr Manoilov, Juan Astorga‐Wells, Ann‐Sofie Jemth, Lang Pan, Kumar Sanjiv, Stella Karsten, Camilla Göktürk, Maurice Grube, Evert Homan, Bishoy Hanna, Cynthia B. J. Paulin, Therese Pham, Azita Rasti, Ulrika Warpman Berglund, Catharina Von Nicolai, Carlos Benitéz‐Buelga, Tobias Koolmeister, Dag Ivanic, Petar Iliev, Martin Scobie, Hans E. Krokan, Paweł Baranczewski, Per Artursson, Mikael Altun, Annika Jenmalm Jensen, Christina Kalderén, Xueqing Ba, Roman A. Zubarev, Pål Stenmark, István Boldogh, Thomas Helleday

    Vydáno 2018
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  8. 8
    Targeting OGG1 arrests cancer cell proliferation by inducing replication stress

    Targeting OGG1 arrests cancer cell proliferation by inducing replication stress Autor Torkild Visnes, Carlos Benitéz‐Buelga, Armando Cázares‐Körner, Kumar Sanjiv, Bishoy Hanna, Oliver Mortusewicz, Varshni Rajagopal, Julian J. Albers, Daniel W. Hagey, Tove Bekkhus, Saeed Eshtad, Juan Miguel Baquero, Geoffrey Masuyer, Olov Wallner, Sarah Müller, Therese Pham, Camilla Göktürk, Azita Rasti, Sharda Suman, Raúl Torres, Antonio Sarno, Elisée Wiita, Evert Homan, Stella Karsten, Karthick Marimuthu, Maurice Michel, Tobias Koolmeister, Martin Scobie, Olga Loseva, Ingrid Almlöf, Judith E. Unterlass, Aleksandra Pettke, Johan Boström, Monica Pandey, Helge Gad, Patrick Herr, Ann‐Sofie Jemth, Samir EL Andaloussi, Christina Kalderén, Sandra Rodríguez, Javier Benı́tez, Hans E. Krokan, Mikael Altun, Pål Stenmark, Ulrika Warpman Berglund, Thomas Helleday

    Vydáno 2020
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  9. 9
    Validation and development of MTH1 inhibitors for treatment of cancer

    Validation and development of MTH1 inhibitors for treatment of cancer Autor Ulrika Warpman Berglund, Kumar Sanjiv, Helge Gad, Christina Kalderén, Tobias Koolmeister, Therese Pham, Camilla Göktürk, Rozbeh Jafari, Gianluca Maddalo, Brinton Seashore‐Ludlow, Alexey Chernobrovkin, Aleksandr Manoilov, Ioannis S. Pateras, Azita Rasti, Ann‐Sofie Jemth, Ingrid Almlöf, Olga Loseva, Torkild Visnes, Berglind O. Einarsdottir, Fabienne Z. Gaugaz, Amyza Saleh, Björn Platzack, Olov Wallner, Karl S. A. Vallin, Martin Henriksson, Prasad B. Wakchaure, Sanjay R. Borhade, Patrick Herr, Yvonne Kallberg, Paweł Baranczewski, Evert Homan, Elisée Wiita, Varun Nagpal, Thomas Meijer, Nicolaas Schipper, Sean G. Rudd, Lars Bräutigam, Annika Lindqvist, Anne M. Filppula, Te‐Chang Lee, Per Artursson, Jonas A. Nilsson, Vassilis G. Gorgoulis, Janne Lehtiö, Roman A. Zubarev, Martin Scobie, Thomas Helleday

    Vydáno 2016
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  10. 10
    Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function

    Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function Autor Maurice Michel, Carlos Benitéz‐Buelga, Patricia A. Calvo, Bishoy Hanna, Oliver Mortusewicz, Geoffrey Masuyer, Jonathan Davies, Olov Wallner, Kumar Sanjiv, Julian J. Albers, Sergio Castañeda‐Zegarra, Ann‐Sofie Jemth, Torkild Visnes, Ana Sastre-Perona, Akhilesh Nagesh Danda, Evert Homan, Karthick Marimuthu, Zhao Zhenjun, N. Celestine, Antonio Sarno, Elisée Wiita, Catharina Von Nicolai, Anna J. Komor, Varshni Rajagopal, Sarah Müller, Emily C. Hank, Marek Varga, Emma Rose Scaletti, Monica Pandey, Stella Karsten, Hanne Haslene‐Hox, Simon Loevenich, Petra Marttila, Azita Rasti, Kirill Mamonov, Florian Ortis, Fritz Schömberg, Olga Loseva, Josephine Stewart, Nicholas D’Arcy-Evans, Tobias Koolmeister, Martin Henriksson, Dana Michel, Ana de Ory, Lucía Acero-Riaguas, Oriol Calvete, Martin Scobie, Christian Hertweck, Ivan Vilotijević, Christina Kalderén, Ana Osório, Rosario Perona, Alexandra Stolz, Pål Stenmark, Ulrika Warpman Berglund, Miguel de Vega, Thomas Helleday

    Vydáno 2022
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  11. 11
    Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

    Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress Autor Nadilly Bonagas, Nina Gustafsson, Martin Henriksson, Petra Marttila, Robert Gustafsson, Elisée Wiita, Sanjay R. Borhade, Alanna C. Green, Karl S. A. Vallin, Antonio Sarno, Richard Svensson, Camilla Göktürk, Therese Pham, Ann‐Sofie Jemth, Olga Loseva, Victoria Cookson, Nicole Kiweler, Lars Sandberg, Azita Rasti, Judith E. Unterlass, Martin Haraldsson, Yasmin Andersson, Emma Rose Scaletti, Christoffer Bengtsson, Cynthia B. J. Paulin, Kumar Sanjiv, Eldar Abdurakhmanov, Linda Pudelko, Ben Kunz, Matthieu Desroses, Petar Iliev, Katarina Färnegårdh, Andreas Krämer, Neeraj Garg, Maurice Michel, Sara Häggblad, Malin Jarvius, Christina Kalderén, Amanda Bögedahl Jensen, Ingrid Almlöf, Stella Karsten, Si Min Zhang, Maria Häggblad, Anders Eriksson, Jianping Liu, Björn Glinghammar, Natalia Nekhotiaeva, Fredrik Klingegård, Tobias Koolmeister, Ulf Märtens, Sabin Llona‐Minguez, Ruth Moulson, Helena Nordström, Vendela Parrow, Leif Dahllund, Birger Sjöberg, Irene Lisa Vargas, Duy Duc Vo, Johan Wannberg, Stefan Knapp, Hans E. Krokan, Per I. Arvidsson, Martin Scobie, Johannes Meiser, Pål Stenmark, Ulrika Warpman Berglund, Evert Homan, Thomas Helleday

    Vydáno 2022
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