Resultats de la cerca - Martin A.M. Reijns

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  1. 1
    Genome-wide mapping of embedded ribonucleotides and other noncanonical nucleotides using emRiboSeq and EndoSeq

    Genome-wide mapping of embedded ribonucleotides and other noncanonical nucleotides using emRiboSeq and EndoSeq per James Ding, Martin S. Taylor, Andrew P. Jackson, Martin A.M. Reijns

    Publicat 2015
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  2. 2
    A role for Q/N-rich aggregation-prone regions in P-body localization

    A role for Q/N-rich aggregation-prone regions in P-body localization per Martin A.M. Reijns, Ross D. Alexander, Michael P. Spiller, Jean D. Beggs

    Publicat 2008
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  3. 3
    Lagging-strand replication shapes the mutational landscape of the genome

    Lagging-strand replication shapes the mutational landscape of the genome per Martin A.M. Reijns, Harriet Kemp, James Ding, Sophie Marion de Procé, Andrew P. Jackson, Martin S. Taylor

    Publicat 2015
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  4. 4
    PCNA directs type 2 RNase H activity on DNA replication and repair substrates

    PCNA directs type 2 RNase H activity on DNA replication and repair substrates per Doryen Bubeck, Martin A.M. Reijns, Stephen C. Graham, Katy R. Astell, E. Yvonne Jones, Andrew P. Jackson

    Publicat 2011
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  5. 5
    Identification of VP19 and VP15 of white spot syndrome virus (WSSV) and glycosylation status of the WSSV major structural proteins

    Identification of VP19 and VP15 of white spot syndrome virus (WSSV) and glycosylation status of the WSSV major structural proteins per M.C.W. van Hulten, Martin A.M. Reijns, A.M.G. Vermeesch, Fokko Zandbergen, Just M. Vlak

    Publicat 2002
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  6. 6
    The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease

    The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease per Martin A.M. Reijns, Doryen Bubeck, Lucien C.D. Gibson, Stephen C. Graham, George S. Baillie, E. Yvonne Jones, Andrew P. Jackson

    Publicat 2010
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  7. 7
    Human RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress

    Human RNase H2 upregulation counteracts oncogene- and chemotherapy-induced replication stress per RJ Wilkins, Abirami Kannan, Siobhan A. Plass, Claire Wilson, Richard D. Kelly, Chenwei Tang, Panagiotis Kotsantis, Martin A.M. Reijns, Aditi Kanhere, Eva Petermann

    Publicat 2025
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  8. 8
    Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair

    Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair per Medini M. Ghodgaonkar, Federico Lazzaro, Maite Olivera-Pimentel, Mariela Artola-Borán, Petr Ćejka, Martin A.M. Reijns, Andrew P. Jackson, Paolo Plevani, Marco Muzi-Falconi, Josef Jiricny

    Publicat 2013
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  9. 9
    Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin

    Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin per Björn Hiller, Anja Hoppe, Christa Haase, Christina Hiller, Nadja Schubert, Werner Müller, Martin A.M. Reijns, Andrew P. Jackson, Thomas A. Kunkel, Joerg Wenzel, Rayk Behrendt, Axel Roers

    Publicat 2018
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  10. 10
    RNA:DNA hybrids are a novel molecular pattern sensed by TLR9

    RNA:DNA hybrids are a novel molecular pattern sensed by TLR9 per Rachel E. Rigby, Lauren M. Webb, Karen J. Mackenzie, Yangyang Li, Andrea Leitch, Martin A.M. Reijns, Rachel J. Lundie, Ailsa Revuelta, Donald J. Davidson, Sandra S. Diebold, Yorgo Modis, Alastair Macdonald, Andrew P. Jackson

    Publicat 2014
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  11. 11
    Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model

    Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model per Chloe F. Moss, Ilaria Dalla Rosa, Lilian Hunt, Takehiro Yasukawa, Robert S. Young, Aleck W.E. Jones, Kaalak Reddy, Radha Desai, Sam Virtue, Greg Elgar, Peter J. Voshol, Martin S. Taylor, Ian Holt, Martin A.M. Reijns, Antonella Spinazzola

    Publicat 2017
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  12. 12
    Human and Mouse Mutations in WDR35 Cause Short-Rib Polydactyly Syndromes Due to Abnormal Ciliogenesis

    Human and Mouse Mutations in WDR35 Cause Short-Rib Polydactyly Syndromes Due to Abnormal Ciliogenesis per Pleasantine Mill, Paul J. Lockhart, Elizabeth Fitzpatrick, Hayley S. Mountford, Emma A. Hall, Martin A.M. Reijns, Margaret Keighren, Melanie Bahlo, Catherine J. Bromhead, Peter S. Budd, Salim Aftimos, Martin B. Delatycki, Ravi Savarirayan, Ian J. Jackson, David J. Amor

    Publicat 2011
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  13. 13
    In silico protein interaction screening uncovers DONSON’s role in replication initiation

    In silico protein interaction screening uncovers DONSON’s role in replication initiation per Yang Lim, Lukas Tamayo-Orrego, E. Schmid, Žygimantė Tarnauskaitė, Olga V. Kochenova, Rhian Gruar, Sachiko Muramatsu, Luke D. Lynch, Aitana Verdu Schlie, Paula L. Carroll, Gheorghe Chistol, Martin A.M. Reijns, Masato T. Kanemaki, Andrew P. Jackson, Johannes C. Walter

    Publicat 2023
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  14. 14
    Ribonuclease H2 mutations induce a <scp>cGAS</scp>/<scp>STING</scp>‐dependent innate immune response

    Ribonuclease H2 mutations induce a <scp>cGAS</scp>/<scp>STING</scp>‐dependent innate immune response per Karen J. Mackenzie, Paula Carroll, Laura A. Lettice, Žygimantė Tarnauskaitė, Kaalak Reddy, Flora Dix, Ailsa Revuelta, E. Abbondati, Rachel E. Rigby, Björn Rabe, Fiona Kilanowski, Graeme R. Grimes, Adeline Fluteau, Paul S. Devenney, Robert E. Hill, Martin A.M. Reijns, Andrew P. Jackson

    Publicat 2016
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  15. 15
    cGAS surveillance of micronuclei links genome instability to innate immunity

    cGAS surveillance of micronuclei links genome instability to innate immunity per Karen J. Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J. Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K. Rainger, Andrea Leitch, Ruby Tamara Osborn, Ann P. Wheeler, Marcin Nowotny, Nick Gilbert, Tamir Chandra, Martin A.M. Reijns, Andrew P. Jackson

    Publicat 2017
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  16. 16
    Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

    Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development per Martin A.M. Reijns, Björn Rabe, Rachel E. Rigby, Pleasantine Mill, Katy R. Astell, Laura A. Lettice, Shelagh Boyle, Andrea Leitch, Margaret Keighren, Fiona Kilanowski, Paul S. Devenney, David Sexton, Graeme R. Grimes, Ian Holt, Robert E. Hill, Martin S. Taylor, Kirstie A. Lawson, Julia R. Dorin, Andrew P. Jackson

    Publicat 2012
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  17. 17
    RNase H2, mutated in Aicardi‐Goutières syndrome, promotes LINE‐1 retrotransposition

    RNase H2, mutated in Aicardi‐Goutières syndrome, promotes LINE‐1 retrotransposition per Maria Benitez‐Guijarro, Cesar Lopez‐Ruiz, Žygimantė Tarnauskaitė, Olga Murina, Mahwish Mian Mohammad, Thomas Williams, Adeline Fluteau, Laura Sánchez, Raquel Vilar‐Astasio, Marta García-Cañadas, David A. Cano, Marie-Jeanne H.C. Kempen, Antonio Sánchez–Pozo, Sara R. Heras, Andrew P. Jackson, Martin A.M. Reijns, José L. García-Pérez

    Publicat 2018
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  18. 18
    CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

    CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions per Michal Zimmermann, Olga Murina, Martin A.M. Reijns, Angelo Agathanggelou, Rachel Challis, Žygimantė Tarnauskaitė, Morwenna Muir, Adeline Fluteau, Michael Aregger, Andrea McEwan, Wei Yuan, Matthew Clarke, Maryou B. Lambros, Shankara Paneesha, Paul Moss, Megha Chandrashekhar, Stéphane Angers, Jason Moffat, Valerie G. Brunton, Traver Hart, Johann S. de Bono, Tatjana Stanković, Andrew P. Jackson, Daniel Durocher

    Publicat 2018
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  19. 19
    Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

    Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions per Patricia Heyn, Clare V. Logan, Adeline Fluteau, Rachel Challis, Tatsiana Auchynnikava, Carol-Anne Martin, Joseph A. Marsh, Francesca Taglini, Fiona Kilanowski, David Parry, Valérie Cormier‐Daire, Chin‐To Fong, Kate Gibson, Vivian Hwa, Lourdes Ibáñez, Stephen P. Robertson, Giorgia Sebastiani, Juri Rappsilber, Robin C. Allshire, Martin A.M. Reijns, Andrew Dauber, Duncan Sproul, Andrew P. Jackson

    Publicat 2018
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  20. 20
    DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes

    DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes per Anna M. Giordano, Marco Luciani, Francesca Gatto, Monah Abou Alezz, Chiara Beghè, Lucrezia della Volpe, Alessandro Migliara, Sara Valsoni, Marco Genua, Monika Dzieciątkowska, Giacomo Frati, Julie Tahraoui‐Bories, Silvia Giliani, Simona Orcesi, Elisa Fazzi, Renato Ostuni, Angelo D’Alessandro, Raffaella Di Micco, Ivan Merelli, Angelo Lombardo, Martin A.M. Reijns, Natalia Gromak, Angela Gritti, Anna Kajaste‐Rudnitski

    Publicat 2022
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