Search Results - Markus Warmuth

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  1. 1
    The Src Family Kinase Hck Interacts with Bcr-Abl by a Kinase-independent Mechanism and Phosphorylates the Grb2-binding Site of Bcr

    The Src Family Kinase Hck Interacts with Bcr-Abl by a Kinase-independent Mechanism and Phosphorylates the Grb2-binding Site of Bcr by Markus Warmuth, Michael Bergmann, Andrea Prieß, Kathrin Häuslmann, Bertold Emmerich, Michael Hallek

    Published 1997
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  2. 2
    Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

    Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion by Lee A. Albacker, Jeremy Wu, Peter Smith, Markus Warmuth, Philip J. Stephens, Ping Zhu, Lihua Yu, Juliann Chmielecki

    Published 2017
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  3. 3
    Dual-specific Src and Abl kinase inhibitors, PP1 and CGP76030, inhibit growth and survival of cells expressing imatinib mesylate–resistant Bcr-Abl kinases

    Dual-specific Src and Abl kinase inhibitors, PP1 and CGP76030, inhibit growth and survival of cells expressing imatinib mesylate–resistant Bcr-Abl kinases by Markus Warmuth, Nicola Simon, Olga Mitina, Ruth Mathes, Doriano Fabbro, Paul W. Manley, Elisabeth Buchdunger, Karin Forster, Ismail Moarefi, Michael Hallek

    Published 2002
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  4. 4
    Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia

    Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia by Yiguo Hu, Yuhua Liu, Shawn D. Pelletier, Elisabeth Buchdunger, Markus Warmuth, Doriano Fabbro, Michael Hallek, Richard A. Van Etten, Shaoguang Li

    Published 2004
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  5. 5
    Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation

    Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation by Christine Dierks, Ronak Beigi, Gui-Rong Guo, Katja Zirlik, Mario Stegert, Paul W. Manley, Christopher Trussell, Annette Schmitt‐Graeff, Klemens Landwerlin, Hendrik Veelken, Markus Warmuth

    Published 2008
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  6. 6
    A General Strategy for Creating “Inactive-Conformation” Abl Inhibitors

    A General Strategy for Creating “Inactive-Conformation” Abl Inhibitors by Okram Barun, A. S. Nagle, Francisco Adrián, Christian Lee, Pingda Ren, Xia Wang, Taebo Sim, Yongping Xie, Xing Wang, Gang Xia, Glen Spraggon, Markus Warmuth, Yi Liu, Nathanael S. Gray

    Published 2006
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  7. 7
    The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells

    The Polycomb Group Protein Bmi-1 Is Essential for the Growth of Multiple Myeloma Cells by Zainab Jagani, Dmitri Wiederschain, Alice Loo, Dan He, Rebecca Mosher, Paul Fordjour, John E. Monahan, Michael Morrissey, Yung-Mae Yao, Christoph Lengauer, Markus Warmuth, William R. Sellers, Marion Dorsch

    Published 2010
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  8. 8
    The ITK-SYK Fusion Oncogene Induces a T-Cell Lymphoproliferative Disease in Mice Mimicking Human Disease

    The ITK-SYK Fusion Oncogene Induces a T-Cell Lymphoproliferative Disease in Mice Mimicking Human Disease by Christine Dierks, Francisco Adrián, Paul Fisch, Hong Ma, Helga Maurer, Dieter Herchenbach, Christine Ulrike Forster, Clara Sprissler, Guoxun Liu, Sabine Rottmann, Gui-Rong Guo, Katja Zirlik, Hendrik Veelken, Markus Warmuth

    Published 2010
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  9. 9
    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes

    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes by Drew Adams, Daisuke Ito, Matthew G. Rees, Brinton Seashore‐Ludlow, Xiaoling Puyang, Alex H. Ramos, Jaime H. Cheah, Paul A. Clemons, Markus Warmuth, Ping Zhu, Alykhan F. Shamji, Stuart L. Schreiber

    Published 2014
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  10. 10
    Protein Kinase C Inhibitor Sotrastaurin Selectively Inhibits the Growth of CD79 Mutant Diffuse Large B-Cell Lymphomas

    Protein Kinase C Inhibitor Sotrastaurin Selectively Inhibits the Growth of CD79 Mutant Diffuse Large B-Cell Lymphomas by Tara L. Naylor, Huaping Tang, Boris A. Ratsch, Andreas Enns, Alice Loo, Liqing Chen, Peter Lenz, Nigel J. Waters, W. Schüler, Bernd Dörken, Yung‐Mae Yao, Markus Warmuth, Georg Lenz, Frank Stegmeier

    Published 2011
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  11. 11
    A Type-II Kinase Inhibitor Capable of Inhibiting the T315I “Gatekeeper” Mutant of Bcr-Abl

    A Type-II Kinase Inhibitor Capable of Inhibiting the T315I “Gatekeeper” Mutant of Bcr-Abl by Hwan Geun Choi, Pingda Ren, Francisco Adrián, Fangxian Sun, Hyun Soo Lee, Xia Wang, Qiang Ding, Guobao Zhang, Yongping Xie, Jianming Zhang, Yi Liu, Tove Tuntland, Markus Warmuth, Paul W. Manley, Jürgen Mestan, Nathanael S. Gray, Taebo Sim

    Published 2010
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  12. 12
    Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK

    Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK by Anna Galkin, Jonathan S. Melnick, Sung Joon Kim, Tami Hood, Nanxin Li, Lintong Li, Gang Xia, Ruo W. Steensma, Greg Chopiuk, Jiqing Jiang, Yongqin Wan, Peter Ding, Yi Liu, Fangxian Sun, Peter G. Schultz, Nathanael S. Gray, Markus Warmuth

    Published 2006
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  13. 13
    Maintenance of adenomatous polyposis coli ( <i>APC</i> )-mutant colorectal cancer is dependent on Wnt/β-catenin signaling

    Maintenance of adenomatous polyposis coli ( <i>APC</i> )-mutant colorectal cancer is dependent on Wnt/β-catenin signaling by Alix Scholer‐Dahirel, Michael R. Schlabach, Alice Loo, Linda Bagdasarian, Ronald A. Meyer, Ribo Guo, Steve Woolfenden, Kristine Yu, Judit Markovits, Karen A. Killary, Dmitriy Sonkin, Yung‐Mae Yao, Markus Warmuth, William R. Sellers, Robert Schlegel, Frank Stegmeier, Rebecca Mosher, Margaret E. McLaughlin

    Published 2011
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  14. 14
    Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators

    Sensitivity to splicing modulation of BCL2 family genes defines cancer therapeutic strategies for splicing modulators by Daniel Aird, Teng Teng, Chia‐Ling Huang, Ermira Pazolli, Deepti Banka, Kahlin Cheung-Ong, Cheryl Eifert, Craig Furman, Zhenhua J. Wu, Michael Seiler, Silvia Buonamici, Peter Fekkes, Craig Karr, James Palacino, Eunice Park, Peter G. Smith, Lihua Yu, Yoshiharu Mizui, Markus Warmuth, Agustin Chicas, Laura Corson, Ping Zhu

    Published 2019
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  15. 15
    Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

    Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist by Shifeng Pan, Xu Wu, Jiqing Jiang, Wenqi Gao, Yongqin Wan, Cheng Dai, Dong Han, Jun Liu, Nathan Englund, Yan Wang, Stefan Peukert, Karen Miller‐Moslin, Jing Yuan, Ribo Guo, Melissa Matsumoto, Anthony Vattay, Yun Jiang, Jeffrey Tsao, Fangxian Sun, AnneMarie Culazzo Pferdekamper, Stephanie Dodd, Tove Tuntland, Wieslawa Maniara, Joseph F. Kelleher, Yung‐Mae Yao, Markus Warmuth, Juliet Williams, Marion Dorsch

    Published 2010
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  16. 16
    An efficient rapid system for profiling the cellular activities of molecular libraries

    An efficient rapid system for profiling the cellular activities of molecular libraries by Jonathan S. Melnick, Jeff Janes, Sung Joon Kim, Jim Chang, Daniel G. Sipes, Drew Gunderson, Laura Jarnes, Jason Matzen, Michael Garcia, Tami Hood, Ronak Beigi, Gang Xia, Richard A. Harig, Hayk Asatryan, S. Frank Yan, Yingyao Zhou, Xiang-ju Gu, Alham Saadat, Vicki Zhou, Frederick J. King, Christopher M. Shaw, Andrew I. Su, Robert T. Downs, Nathanael S. Gray, Peter G. Schultz, Markus Warmuth, Jeremy S. Caldwell

    Published 2006
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  17. 17
    Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex

    Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex by Teng Teng, Jennifer Tsai, Xiaoling Puyang, Michael Seiler, Shouyong Peng, Sudeep Prajapati, Daniel Aird, Silvia Buonamici, Benjamin Caleb, Betty Chan, Laura Corson, Jacob Feala, Peter Fekkes, Baudouin Gerard, Craig Karr, Manav Korpal, Xiang Liu, Jason T. Lowe, Yoshiharu Mizui, James Palacino, Eunice Park, Peter G. Smith, Vanitha Subramanian, Zhenhua J. Wu, Jian Zou, Lihua Yu, Agustin Chicas, Markus Warmuth, Nicholas Larsen, Ping Zhu

    Published 2017
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  18. 18
    Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

    Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma by Silvia Buonamici, Juliet Williams, Michael Morrissey, Anlai Wang, Ribo Guo, Anthony Vattay, Kathy Hsiao, Jing Yuan, John Green, Beatriz Muñoz, Qunyan Yu, Lance Ostrom, Paul Fordjour, Dustin L. Anderson, John E. Monahan, Joseph F. Kelleher, Stefan Peukert, Shifeng Pan, Xu Wu, Sauveur-Michel Maira, Carlos Garcı́a-Echeverrı́a, Kimberly J. Briggs, D. Neil Watkins, Yung-Mae Yao, Christoph Lengauer, Markus Warmuth, William R. Sellers, Marion Dorsch

    Published 2010
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  19. 19
    Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway

    Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway by Zainab Jagani, E. Lorena Mora‐Blanco, Courtney G. Sansam, Elizabeth S. McKenna, Boris G. Wilson, Dongshu Chen, Justin Klekota, Pablo Tamayo, Phuong Nguyen, Michael Tolstorukov, Peter J. Park, Yoon-Jae Cho, Kathy Hsiao, Silvia Buonamici, Scott L. Pomeroy, Jill P. Mesirov, Heinz Ruffner, Tewis Bouwmeester, Sarah J. Luchansky, Joshua Murtie, Joseph F. Kelleher, Markus Warmuth, William R. Sellers, Charles W.M. Roberts, Marion Dorsch

    Published 2010
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  20. 20
    Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

    Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors by Jianming Zhang, Francisco Adrián, Wolfgang Jahnke, Sandra W. Cowan‐Jacob, Allen G. Li, Roxana E. Iacob, Taebo Sim, John T. Powers, Christine Dierks, Fangxian Sun, Gui-Rong Guo, Qiang Ding, Okram Barun, Yongmun Choi, Amy Wojciechowski, Xianming Deng, Guoxun Liu, Gabriele Fendrich, André Strauss, Navratna Vajpai, Stephan Grzesiek, Tove Tuntland, Yi Liu, Badry Bursulaya, Mohammad Azam, Paul W. Manley, John R. Engen, George Q. Daley, Markus Warmuth, Nathanael S. Gray

    Published 2010
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