Search Results - Mark Tremelling

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  1. 1
    Genetic association between NLRP3 variants and Crohnʼs disease does not replicate in a large UK panel

    Genetic association between NLRP3 variants and Crohnʼs disease does not replicate in a large UK panel by Gregory J. Lewis, Dunecan Massey, Hu Zhang, Francesca Bredin, Mark Tremelling, James Lee, Carlo Berzuini, Miles Parkes

    Published 2010
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  2. 2
    Contribution of TNFSF15 gene variants to Crohnʼs disease susceptibility confirmed in UK population

    Contribution of TNFSF15 gene variants to Crohnʼs disease susceptibility confirmed in UK population by Mark Tremelling, Carlo Berzuini, Dunecan Massey, Francesca Bredin, C.J. Price, Claire Dawson, Sheila Bingham, Miles Parkes

    Published 2008
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  3. 3
    The Impact of NOD2 Variants on Fecal Microbiota in Crohn’s Disease and Controls Without Gastrointestinal Disease

    The Impact of NOD2 Variants on Fecal Microbiota in Crohn’s Disease and Controls Without Gastrointestinal Disease by Nicholas A. Kennedy, Christopher A Lamb, Susan H. Berry, Alan W. Walker, John Mansfield, Miles Parkes, Rachel Simpkins, Mark Tremelling, Sarah Nutland, Julian Parkhill, Chris Probert, Georgina L. Hold, Charlie W. Lees

    Published 2018
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  4. 4
    IL23R Variation Determines Susceptibility But Not Disease Phenotype in Inflammatory Bowel Disease

    IL23R Variation Determines Susceptibility But Not Disease Phenotype in Inflammatory Bowel Disease by Mark Tremelling, Fraser Cummings, Sheila Fisher, John Mansfield, Rhian Gwilliam, Andrew Keniry, Elaine R. Nimmo, Hazel E. Drummond, Clive M. Onnie, Natalie J. Prescott, Jeremy Sanderson, Francesca Bredin, Carlo Berzuini, Alastair Forbes, Cathryn M. Lewis, Lon R. Cardon, Panos Deloukas, Derek P. Jewell, Christopher G. Mathew, Miles Parkes, Jack Satsangi

    Published 2007
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  5. 5
    Analysis of Germline GLI1 Variation Implicates Hedgehog Signalling in the Regulation of Intestinal Inflammatory Pathways

    Analysis of Germline GLI1 Variation Implicates Hedgehog Signalling in the Regulation of Intestinal Inflammatory Pathways by Charlie W. Lees, William J. Zacharias, Mark Tremelling, Colin Noble, Elaine R. Nimmo, Albert Tenesa, Jennine Cornelius, Leif Törkvist, John Y. Kao, Susan M. Farrington, Hazel E. Drummond, Gwo–Tzer Ho, I. Arnott, Henry D. Appelman, Lauri Diehl, Harry Campbell, Malcolm G. Dunlop, Miles Parkes, Sarah Howie, Deborah L. Gumucio, Jack Satsangi

    Published 2008
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  6. 6
    Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7

    Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7 by Yang Luo, Katrina M. de Lange, Luke Jostins, Loukas Moutsianas, Joshua C. Randall, Nicholas A. Kennedy, Christopher A Lamb, Shane McCarthy, Tariq Ahmad, Cathryn Edwards, Eva Serra, Ailsa Hart, C J Hawkey, John Mansfield, Craig Mowat, William G. Newman, Sam Nichols, Martin Pollard, Jack Satsangi, Alison Simmons, Mark Tremelling, Holm H. Uhlig, David C. Wilson, James Lee, Natalie J. Prescott, Charlie W. Lees, Christopher G. Mathew, Miles Parkes, Jeffrey C. Barrett, Carl A. Anderson

    Published 2017
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  7. 7
    Blockage of bacterial FimH prevents mucosal inflammation associated with Crohn’s disease

    Blockage of bacterial FimH prevents mucosal inflammation associated with Crohn’s disease by Grégoire Chevalier, Arnaud Laveissière, Guillaume Desachy, Nicolas Barnich, Adeline Sivignon, Marc Maresca, Cendrine Nicoletti, Eric Di Pasquale, Margarita Martínez-Medina, Kenneth W. Simpson, Vijay Yajnik, Harry Sokol, Temitayo Adegbamigbe, Tariq Ahmad, Ian Arnott, Yoram Bouhnik, Franck Carbonnel, Jean–Frédéric Colombel, Glen Doherty, Fraser Cummings, Xavier Hébuterne, Hans Herfarth, David Kevans, Guillaume Pineton de Chambrun, Maria Nachury, Stéphane Nancey, Xavier Roblin, Mark Tremelling, Jonathan Plassais, Francesco Strozzi, Alessandra Cervino, Rachel Morra, Christophe Bonny

    Published 2021
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  8. 8
    Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

    Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility by Miles Parkes, Jeffrey C. Barrett, Natalie J. Prescott, Mark Tremelling, Carl A. Anderson, Sheila Fisher, Roland G. Roberts, Elaine R. Nimmo, Fraser Cummings, Dianne Soars, Hazel E. Drummond, Charlie W. Lees, Saud Khawaja, Richard D. Bagnall, Denis Burke, Catherine E Todhunter, Tariq Ahmad, Clive M. Onnie, Wendy L. McArdle, David P. Strachan, Graeme Bethel, Claire Bryan, Cathryn M. Lewis, Panos Deloukas, Alastair Forbes, Jeremy Sanderson, Derek P. Jewell, Jack Satsangi, John Mansfield, Lon R. Cardon, Christopher G. Mathew

    Published 2007
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  9. 9
    Investigation of Crohn's Disease Risk Loci in Ulcerative Colitis Further Defines Their Molecular Relationship

    Investigation of Crohn's Disease Risk Loci in Ulcerative Colitis Further Defines Their Molecular Relationship by Carl A. Anderson, Dunecan Massey, Jeffrey C. Barrett, Natalie J. Prescott, Mark Tremelling, Sheila Fisher, Rhian Gwilliam, Jemima Jacob, Elaine R. Nimmo, Hazel E. Drummond, Charlie W. Lees, Clive M. Onnie, Catherine Hanson, Katarzyna Błaszczyk, Rathi Ravindrarajah, Sarah Hunt, Dhiraj Varma, Naomi Hammond, Gregory J. Lewis, Heather Attlesey, Nick Watkins, Willem H. Ouwehand, David P. Strachan, Wendy L. McArdle, Cathryn M. Lewis, Alan Lobo, Jeremy Sanderson, Derek P. Jewell, Panos Deloukas, John Mansfield, Christopher G. Mathew, Jack Satsangi, Miles Parkes

    Published 2008
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  10. 10
    Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

    Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease by Katrina M. de Lange, Loukas Moutsianas, James Lee, Christopher A Lamb, Yang Luo, Nicholas A. Kennedy, Luke Jostins, Daniel L Rice, Javier Gutierrez‐Achury, Sun‐Gou Ji, Graham Heap, Elaine R. Nimmo, Cathryn Edwards, Paul Henderson, Craig Mowat, Jeremy Sanderson, Jack Satsangi, Alison Simmons, David C. Wilson, Mark Tremelling, Ailsa Hart, Christopher G. Mathew, William G. Newman, Miles Parkes, Charlie W. Lees, Holm H. Uhlig, C J Hawkey, Natalie J. Prescott, Tariq Ahmad, John Mansfield, Carl A. Anderson, Jeffrey C. Barrett

    Published 2017
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  11. 11
    Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

    Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease by Sheila Fisher, Mark Tremelling, Carl A. Anderson, Rhian Gwilliam, Suzannah Bumpstead, Natalie J. Prescott, Elaine R. Nimmo, Dunecan Massey, Carlo Berzuini, C. Mark Johnson, Jeffrey C. Barrett, Fraser Cummings, Hazel E. Drummond, Charlie W. Lees, Clive M. Onnie, Catherine Hanson, Katarzyna Błaszczyk, Michael Inouye, Philip Ewels, Rathi Ravindrarajah, Andrew Keniry, Sarah Hunt, Martyn Carter, Nick Watkins, Willem H. Ouwehand, Cathryn M. Lewis, Lon R. Cardon, Alan Lobo, Alastair Forbes, Jeremy Sanderson, Derek P. Jewell, John Mansfield, Panos Deloukas, Christopher G. Mathew, Miles Parkes, Jack Satsangi

    Published 2008
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  12. 12
    HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

    HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants by Graham Heap, Michael N. Weedon, Claire Bewshea, Abhey Singh, Mian Chen, Jack Satchwell, J.P. Vivian, Kenji So, P Dubois, Jane M. Andrews, Vito Annese, Peter A. Bampton, Martin Barnardo, Sally Bell, Andy Cole, Susan J. Connor, Tom Creed, Fraser Cummings, Mauro D’Amato, Tawfique K. Daneshmend, Richard N. Fedorak, Timothy H. Florin, Daniel R. Gaya, Emma I. Greig, Jonas Halfvarson, Alisa Hart, Peter M. Irving, Gareth‐Rhys Jones, Amir Karban, Ian C. Lawrance, James Lee, Charlie W. Lees, Raffi Lev‐Tzion, James O. Lindsay, John Mansfield, Joel Mawdsley, Zia Mazhar, Miles Parkes, Kirstie Parnell, Timothy R. Orchard, Graham Radford‐Smith, Richard K. Russell, David Reffitt, Jack Satsangi, Mark S. Silverberg, G Sturniolo, Mark Tremelling, Epameinondas V. Tsianos, David A. van Heel, Alissa Walsh, Gill Watermeyer, Rinse K. Weersma, Sebastian Zeißig, Jamie Rossjohn, Arthur L. Holden, Tariq Ahmad

    Published 2014
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  13. 13
    Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

    Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease by Jeffrey C. Barrett, Sarah Hansoul, Dan L. Nicolae, Judy H. Cho, Richard H. Duerr, John D. Rioux, Steven R. Brant, Mark S. Silverberg, Kent D. Taylor, M. Michael Barmada, Alain Bitton, Themistocles Dassopoulos, Lisa W. Datta, Todd J. Green, Anne M. Griffiths, Emily O. Kistner, Michael T. Murtha, Miguel Regueiro, Jerome I. Rotter, L. Philip Schumm, A. Hillary Steinhart, Stephan R. Targan, Ramnik J. Xavier, Cécile Libioulle, Cynthia Sandor, Mark Lathrop, Jacques Bélaïche, Olivier Dewit, Marta Gut, Simon Heath, Debby Laukens, Myriam Mni, Paul Rutgeerts, A. Van Gossum, Diana Zélénika, Denis Franchimont, Jean‐Pierre Hugot, Martine De Vos, Séverine Vermeire, Édouard Louis, Lon R. Cardon, Carl A. Anderson, Hazel E. Drummond, Elaine R. Nimmo, Tariq Ahmad, Natalie J. Prescott, Clive M. Onnie, Sheila Fisher, Jonathan Marchini, Jilur Ghori, Suzannah Bumpstead, Rhian Gwilliam, Mark Tremelling, Panos Deloukas, John Mansfield, Derek P. Jewell, Jack Satsangi, Christopher G. Mathew, Miles Parkes, Michel Georges, Mark J. Daly

    Published 2008
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  14. 14
    A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

    A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis by Manuel A. Rivas, Daniel B. Graham, Patrick Sulem, Christine Stevens, A. Nicole Desch, Philippe Goyette, Daníel F. Guðbjartsson, Ingileif Jónsdóttir, Unnur Þorsteinsdóttir, Frauke Degenhardt, Sören Mucha, Mitja Kurki, Dalin Li, Mauro D’Amato, Vito Annese, Séverine Vermeire, Rinse K. Weersma, Jonas Halfvarson, Paulina Paavola–Sakki, Maarit Lappalainen, Monkol Lek, Beryl B. Cummings, Taru Tukiainen, Talin Haritunians, Leena Halme, Lotta L. E. Koskinen, Ashwin N. Ananthakrishnan, Yang Luo, Graham Heap, Marijn C. Visschedijk, Jeffrey C. Barrett, Kim de Lange, Cathryn Edwards, AL Hart, C J Hawkey, Luke Jostins, Nicholas A. Kennedy, Christopher A Lamb, James Lee, Charlie W. Lees, John Mansfield, Christopher G. Mathew, C. Mowatt, William G. Newman, Elaine Nimmo, Miles Parkes, Martin Pollard, Natalie J. Prescott, Jessica Randall, Daniel L Rice, Jack Satsangi, Alison Simmons, Mark Tremelling, Holm H. Uhlig, David C. Wilson, Clara Abraham, J ACHKAR, Alain Bitton, Gabrielle Boucher, Kenneth Croitoru, Phil Fleshner, Jürgen Glas, Subra Kugathasan, Johan Van Limbergen, Raquel Milgrom, Deborah D. Proctor, Miguel Regueiro, L. Philip Schumm, Yashoda Sharma, Joanne M. Stempak, Stephan R. Targan, M. H. Wang, Daniel G. MacArthur, Benjamin M. Neale, Tariq Ahmad, Carl A. Anderson, Steven R. Brant, Richard H. Duerr, Mark S. Silverberg, Judy H. Cho, Aarno Palotie, Päivi Saavalainen, Kimmo Kontula, Martti Färkkilâ, Dermot McGovern, André Franke, Kāri Stefánsson, John D. Rioux, Ramnik J. Xavier, Mark J. Daly

    Published 2016
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  15. 15
    Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease by Luke Jostins, Stephan Ripke, Rinse K. Weersma, Richard H. Duerr, Dermot McGovern, Ken Y. Hui, James Lee, L. Philip Schumm, Yashoda Sharma, Carl A. Anderson, Jonah Essers, Mitja Mitrovič, Kaida Ning, Isabelle Cleynen, Emilie Théâtre, Sarah L. Spain, Soumya Raychaudhuri, Philippe Goyette, Zhi Wei, Clara Abraham, Jean‐Paul Achkar, Tariq Ahmad, Leila Amininejad, Ashwin N. Ananthakrishnan, Vibeke Andersen, Jane M. Andrews, Leonard Baidoo, Tobias Balschun, Peter A. Bampton, Alain Bitton, Gabrielle Boucher, Stephan Brand, Carsten Büning, Ariella Cohain, Sven Cichon, Mauro D’Amato, Dirk de Jong, Kathy L. Devaney, Marla C. Dubinsky, Cathryn Edwards, David Ellinghaus, Lynnette Ferguson, Denis Franchimont, Karin Fransén, Richard B. Gearry, Michel Georges, Christian Gieger, Jürgen Glas, Talin Haritunians, Ailsa Hart, Chris Hawkey, Matija Hedl, Xinli Hu, Tom H. Karlsen, Limas Kupčinskas, Subra Kugathasan, Anna Latiano, Debby Laukens, Ian C. Lawrance, Charlie W. Lees, Édouard Louis, Gillian Mahy, John Mansfield, Ann W. Morgan, Craig Mowat, William G. Newman, Orazio Palmieri, Cyriel Y. Ponsioen, Uroš Potočnik, Natalie J. Prescott, Miguel Regueiro, Jerome I. Rotter, Richard K. Russell, Jeremy Sanderson, Miquel Sans, Jack Satsangi, Stefan Schreiber, Lisa A. Simms, Jurgita Šventoraitytė, Stephan R. Targan, Kent D. Taylor, Mark Tremelling, Hein W. Verspaget, Paul Martin, Cisca Wijmenga, David C. Wilson, Juliane Winkelmann, Ramnik J. Xavier, Sebastian Zeißig, Bin Zhang, Hu Zhang, Hongyu Zhao, Mark S. Silverberg, Vito Annese, Hákon Hákonarson, Steven R. Brant, Graham Radford‐Smith, Christopher G. Mathew, John D. Rioux, Eric E. Schadt

    Published 2012
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  16. 16
    Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants by Paul R. Burton, David Clayton, Lon R. Cardon, Nick Craddock, Panos Deloukas, Audrey Duncanson, Dominic Kwiatkowski, Mark I. McCarthy, Willem H. Ouwehand, Nilesh J. Samani, John A. Todd, Peter Donnelly, Jeffrey C. Barrett, Dan Davison, Doug Easton, David M. Evans, H.T. Leung, Jonathan Marchini, Andrew P. Morris, Chris C. A. Spencer, Martin D. Tobin, Antony Attwood, James P. Boorman, Barbara Cant, Ursula Everson, Judith M. Hussey, Jennifer D. Jolley, Alexandra S. Knight, Kerstin Koch, Elizabeth Meech, Sarah Nutland, C V Prowse, H. E. Stevens, Niall Taylor, Graham R. Walters, Neil Walker, Nicholas A. Watkins, Thilo Winzer, Richard W. Jones, Wendy L. McArdle, Susan M. Ring, David P. Strachan, Marcus Pembrey, Gerome Breen, David St Clair, Sian Caesar, Katharine Gordon-Smith, Lisa Jones, Christine Fraser, Elaine Green, Detelina Grozeva, Marian L. Hamshere, Peter Holmans, Ian Jones, George Kirov, Valentina Moskivina, Ivan Nikolov, Michael O’Donovan, Michael J. Owen, David Collier, Amanda Elkin, Anne Farmer, Richard Williamson, Peter McGuffin, Allan H. Young, I. Nicol Ferrier, Stephen G. Ball, Anthony J. Balmforth, Jennifer H. Barrett, D. Timothy Bishop, Mark M. Iles, Azhar Maqbool, Nadira Yuldasheva, Alistair S. Hall, Peter S. Braund, Richard J. Dixon, Massimo Mangino, Suzanne Stevens, John R. Thompson, Francesca Bredin, Mark Tremelling, Miles Parkes, Hazel E. Drummond, Charlie W. Lees, Elaine R. Nimmo, Jack Satsangi, Sheila Fisher, Alastair Forbes, Cathryn M. Lewis, Clive M. Onnie, Natalie J. Prescott, Jeremy Sanderson, Christopher G Matthew, Jamie Barbour, Mohamed Khalid Mohiuddin, Catherine E Todhunter, John Mansfield, Tariq Ahmad, Fraser Cummings, Derek P. Jewell

    Published 2007
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  17. 17
    Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls by Paul R. Burton, David Clayton, Lon R. Cardon, Nick Craddock, Panos Deloukas, Audrey Duncanson, Dominic Kwiatkowski, Mark I. McCarthy, Willem H. Ouwehand, Nilesh J. Samani, John A. Todd, Peter Donnelly, Jeffrey C. Barrett, Paul R. Burton, Doug Easton, Peter Donnelly, H.T. Leung, Jonathan L. Marchini, Andrew P. Morris, Jonathan L. Marchini, Martin D. Tobin, Antony Attwood, Martin D. Tobin, Lon R. Cardon, David Clayton, Antony Attwood, James P. Boorman, Barbara Cant, Ursula Everson, Judith M. Hussey, Jennifer D. Jolley, Alexandra S. Knight, Kerstin Koch, Elizabeth Meech, Nicholas J. Timpson, C V Prowse, Eleftheria Zeggini, Niall Taylor, Graham R. Walters, Melanie J. Newport, Nicholas A. Watkins, Thilo Winzer, John A. Todd, Willem H. Ouwehand, Richard W. Jones, Wendy L. McArdle, Susan M. Ring, David P. Strachan, Marcus Pembrey, Gerome Breen, David St Clair, Sian Caesar, Katherine Gordon‐Smith, Lisa Jones, Christine Fraser, Elaine Green, Detelina Grozeva, Marian L. Hamshere, Peter Holmans, Ian Jones, George Kirov, Valentina Moskvina, Ivan Nikolov, Michael O’Donovan, Michael J. Owen, Nick Craddock, David Collier, Amanda Elkin, Anne Farmer, Richard Williamson, Peter McGuffin, Allan H. Young, I. Nicol Ferrier, Stephen G. Ball, Anthony J. Balmforth, Jennifer H. Barrett, D. Timothy Bishop, Mark M. Iles, Azhar Maqbool, Nadira Yuldasheva, Alistair S. Hall, Peter S. Braund, Paul R. Burton, Richard J. Dixon, Massimo Mangino, Suzanne Stevens, Martin D. Tobin, J. Thompson, Nilesh J. Samani, Francesca Bredin, Mark Tremelling, Miles Parkes, Hazel E. Drummond, Charlie W. Lees, Elaine R. Nimmo, Jack Satsangi, Sheila Fisher, Alastair Forbes, Cathryn M. Lewis, Clive M. Onnie

    Published 2007
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