Search Results - Mark C. de Gooijer

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  1. 1
    <scp>ABCB</scp>1 and <scp>ABCG</scp>2 restrict the brain penetration of a panel of novel <scp>EZH</scp>2‐Inhibitors

    <scp>ABCB</scp>1 and <scp>ABCG</scp>2 restrict the brain penetration of a panel of novel <scp>EZH</scp>2‐Inhibitors by Ping Zhang, Mark C. de Gooijer, Levi C.M. Buil, Jos H. Beijnen, Gang Li, Olaf van Tellingen

    Published 2015
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  2. 2
    The G2 checkpoint—a node‐based molecular switch

    The G2 checkpoint—a node‐based molecular switch by Mark C. de Gooijer, Arnout van den Top, Irena Bočkaj, Jos H. Beijnen, Thomas Würdinger, Olaf van Tellingen

    Published 2017
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  3. 3
    The impact of P‐glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors

    The impact of P‐glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors by Mark C. de Gooijer, Ping Zhang, Ruud Weijer, Levi C.M. Buil, Jos H. Beijnen, Olaf van Tellingen

    Published 2017
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  4. 4
    Identification of a Druggable Pathway Controlling Glioblastoma Invasiveness

    Identification of a Druggable Pathway Controlling Glioblastoma Invasiveness by Nora Pencheva, Mark C. de Gooijer, Daniël J. Vis, Lodewyk F.A. Wessels, Tom Würdinger, Olaf van Tellingen, René Bernards

    Published 2017
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  5. 5
    Buparlisib is a brain penetrable pan-PI3K inhibitor

    Buparlisib is a brain penetrable pan-PI3K inhibitor by Mark C. de Gooijer, Ping Zhang, Levi C.M. Buil, Ceren H. Çitirikkaya, Nishita Thota, Jos H. Beijnen, Olaf van Tellingen

    Published 2018
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  6. 6
    Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2

    Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2 by Mark C. de Gooijer, Nienke A. de Vries, Tessa Buckle, Levi C.M. Buil, Jos H. Beijnen, Willem Boogerd, Olaf van Tellingen

    Published 2018
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  7. 7
    ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost

    ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost by Mark C. de Gooijer, E. Marleen Kemper, Levi C.M. Buil, Ceren H. Çitirikkaya, Tessa Buckle, Jos H. Beijnen, Olaf van Tellingen

    Published 2021
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  8. 8
    The impact of ATP-binding cassette transporters in the diseased brain: Context matters

    The impact of ATP-binding cassette transporters in the diseased brain: Context matters by Chrysiida Baltira, Eleonora Aronica, William F. Elmquist, Oliver Langer, Wolfgang Löscher, Jann N. Sarkaria, Pieter Wesseling, Mark C. de Gooijer, Olaf van Tellingen

    Published 2024
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  9. 9
    ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy

    ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy by Fan Lin, Mark C. de Gooijer, Eloy Moreno Roig, Levi C.M. Buil, Susan M. Christner, Jan H. Beumer, Thomas Würdinger, Jos H. Beijnen, Olaf van Tellingen

    Published 2014
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  10. 10
    PI3K–mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models

    PI3K–mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models by Fan Lin, Mark C. de Gooijer, Diana Hanekamp, G. Chandrasekaran, Levi C.M. Buil, Nishita Thota, Rolf W. Sparidans, Jos H. Beijnen, Tom Würdinger, Olaf van Tellingen

    Published 2016
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  11. 11
    NAC regulates metabolism and cell fate in intestinal stem cells

    NAC regulates metabolism and cell fate in intestinal stem cells by Sofia Ramalho, Ferhat Alkan, Stefan Prekovic, Katarzyna Jastrzebski, Eric Pintó Barberà, Liesbeth Hoekman, Maarten Altelaar, Cecilia de Heus, Nalan Liv, Maria J. Rodríguez Colman, Mehmet Yılmaz, Rob van der Kammen, Juliette Fédry, Mark C. de Gooijer, Saskia J.E. Suijkerbuijk, William J. Faller, Joana Silva

    Published 2025
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  12. 12
    MELK Inhibition in Diffuse Intrinsic Pontine Glioma

    MELK Inhibition in Diffuse Intrinsic Pontine Glioma by Michaël H. Meel, Mark C. de Gooijer, Míriam Guillén Navarro, Piotr Waranecki, Marjolein Breur, Levi C.M. Buil, Laurine E. Wedekind, Jos W. R. Twisk, Jan Köster, Rintaro Hashizume, Eric H. Raabe, Ángel M. Carcaboso, Marianna Bugiani, Olaf van Tellingen, Dannis G. van Vuurden, Gertjan J.L. Kaspers, Esther Hulleman

    Published 2018
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  13. 13
    Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma

    Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma by Michaël H. Meel, Mark C. de Gooijer, Dennis S. Metselaar, A. Sewing, Kenn Zwaan, Piotr Waranecki, Marjolein Breur, Levi C.M. Buil, Tonny Lagerweij, Laurine E. Wedekind, Jos W. R. Twisk, Jan Köster, Rintaro Hashizume, Eric H. Raabe, Ángel M. Carcaboso, Marianna Bugiani, Timothy N. Phoenix, Olaf van Tellingen, Dannis G. van Vuurden, Gertjan J.L. Kaspers, Esther Hulleman

    Published 2020
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  14. 14
    Tryptophan depletion results in tryptophan-to-phenylalanine substitutants

    Tryptophan depletion results in tryptophan-to-phenylalanine substitutants by Abhijeet Pataskar, Julien Champagne, Remco Nagel, Juliana C.N. Kenski, Maarja Laos, Justine Michaux, Hui Song Pak, Onno B. Bleijerveld, Kelly Mordente, Jasmine Montenegro Navarro, Naomi Blommaert, Morten M. Nielsen, Domenica Lovecchio, Everett Stone, George Georgiou, Mark C. de Gooijer, Olaf van Tellingen, Maarten Altelaar, Robbie P. Joosten, Anastassis Perrakis, Johanna Olweus, Michal Bassani‐Sternberg, Daniel S. Peeper, Reuven Agami

    Published 2022
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  15. 15
    Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8

    Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8 by Jordi Berenguer, Tonny Lagerweij, Xi Zhao, Sophie A. Dusoswa, Petra van der Stoop, Bart A. Westerman, Mark C. de Gooijer, Marloes Zoetemelk, Anoek Zomer, Matheus H. W. Crommentuijn, Laurine E. Wedekind, Àlan López‐López, Alberta Giovanazzi, Marina Bruch‐Oms, Ida H. van der Meulen‐Muileman, Rogier M. Reijmers, Toin H. Van Kuppevelt, Juan J. García‐Vallejo, Yvette van Kooyk, Bakhos A. Tannous, Pieter Wesseling, Danijela Koppers‐Lalic, W. Peter Vandertop, David P. Noske, Victor W. van Beusechem, Jacco van Rheenen, D. Michiel Pegtel, Olaf van Tellingen, Thomas Würdinger

    Published 2018
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