Search Results - Mark A. Ator
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A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis by Kristine L. Stump, Lily Lu, Paweł Dobrzański, Cynthia Serdikoff, Diane E. Gingrich, Benjamin J. Dugan, Thelma S. Angeles, Mark S. Albom, Mark A. Ator, Bruce D. Dorsey, Bruce Ruggeri, Matthew M. Seavey
Published 2011Artigo -
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Depletion of Autoreactive Plasma Cells and Treatment of Lupus Nephritis in Mice Using CEP-33779, a Novel, Orally Active, Selective Inhibitor of JAK2 by Lily Lu, Kristine L. Stump, Nate H. Wallace, Paweł Dobrzański, Cynthia Serdikoff, Diane E. Gingrich, Benjamin J. Dugan, Thelma S. Angeles, Mark S. Albom, Jennifer Mason, Mark A. Ator, Bruce D. Dorsey, Bruce Ruggeri, Matthew M. Seavey
Published 2011Artigo -
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CEP-28122, a Highly Potent and Selective Orally Active Inhibitor of Anaplastic Lymphoma Kinase with Antitumor Activity in Experimental Models of Human Cancers by Mangeng Cheng, Matthew R. Quail, Diane E. Gingrich, Gregory R. Ott, Lihui Lü, Weihua Wan, Mark S. Albom, Thelma S. Angeles, Lisa D. Aimone, Flavio Cristofani, Rodolfo Machiorlatti, Cristina Abele, Mark A. Ator, Bruce D. Dorsey, Giorgio Inghirami, Bruce Ruggeri
Published 2011Artigo -
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Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor by Joel Kaye, Victor Piryatinsky, Tal Birnberg, Tal Hingaly, Emanuel Raymond, Rina Kashi, Einat Amit‐Romach, Ignacio Caballero, Fadi Towfic, Mark A. Ator, Efrat Rubinstein, Daphna Laifenfeld, Aric Orbach, Doron Shinar, Yael Marantz, Iris Grossman, Volker Knappertz, Michael R. Hayden, Ralph Laufer
Published 2016Artigo -
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Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer by Weiguo Xiang, Lijie Zhao, Xin Han, Tianfeng Xu, Steven Kregel, Mi Wang, Bukeyan Miao, Chong Qin, Mingliang Wang, Donna McEachern, Jianfeng Lü, Longchuan Bai, Chao‐Yie Yang, Paul D. Kirchhoff, John Takyi‐Williams, Lu Wang, Bo Wen, Duxin Sun, Mark A. Ator, Robert McKean, Arul M. Chinnaiyan, Shaomeng Wang
Published 2023Artigo -
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Combined inhibition of atypical PKC and histone deacetylase 1 is cooperative in basal cell carcinoma treatment by Amar Mirza, Micah A. Fry, N. Urman, Scott X. Atwood, Jon Roffey, Gregory R. Ott, Bin Chen, Alex Lee, Alexander S. Brown, Sumaira Z. Aasi, Tyler Hollmig, Mark A. Ator, Bruce D. Dorsey, Bruce Ruggeri, Craig A. Zificsak, Marina Sirota, Jean Y. Tang, Atul J. Butte, Ervin H. Epstein, Kavita Y. Sarin, Anthony E. Oro
Published 2017Artigo -
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CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and <i>In Vivo</i> Antitumor Activity by Joyce James, Bruce Ruggeri, Robert C. Armstrong, Martin W. Rowbottom, Susan Jones‐Bolin, Ruwanthi N. Gunawardane, Paweł Dobrzański, Michael F. Gardner, Hugh Zhao, Merryl Cramer, Kathryn Hunter, Ronald R. Nepomuceno, Mangeng Cheng, Dana Gitnick, Mehran Yazdanian, Darren E. Insko, Mark A. Ator, Julius Apuy, Raffaella Faraoni, Bruce D. Dorsey, Michael Williams, Shripad S. Bhagwat, Mark W. Holladay
Published 2012Artigo
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