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  1. 1
    Recent Developments in Gene Therapy for Homozygous Familial Hypercholesterolemia

    Recent Developments in Gene Therapy for Homozygous Familial Hypercholesterolemia por Ezim Ajufo, Marina Cuchel

    Publicado em 2016
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  2. 2
    Gene editing for dyslipidemias: New tools to “cut” lipids

    Gene editing for dyslipidemias: New tools to “cut” lipids por Sylvia Stankov, Marina Cuchel

    Publicado em 2023
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  3. 3
    Macrophage Reverse Cholesterol Transport

    Macrophage Reverse Cholesterol Transport por Marina Cuchel, Daniel J. Rader

    Publicado em 2006
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  4. 4
    Impact of age on the metabolism of VLDL, IDL, and LDL apolipoprotein B-100 in men.

    Impact of age on the metabolism of VLDL, IDL, and LDL apolipoprotein B-100 in men. por John S. Millar, A. Lichtenstein, Marina Cuchel, Gregory G. Dolnikowski, David L. Hachey, Jeffrey S. Cohn, Ernst J. Schaefer

    Publicado em 1995
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  5. 5
    The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages

    The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages por Margarita de la Llera-Moya, Denise Drazul‐Schrader, Bela F. Asztalos, Marina Cuchel, Daniel J. Rader, George H. Rothblat

    Publicado em 2010
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  6. 6
    High-Density Lipoprotein (HDL) Phospholipid Content and Cholesterol Efflux Capacity Are Reduced in Patients With Very High HDL Cholesterol and Coronary Disease

    High-Density Lipoprotein (HDL) Phospholipid Content and Cholesterol Efflux Capacity Are Reduced in Patients With Very High HDL Cholesterol and Coronary Disease por Anandita Agarwala, Amrith Rodrigues, Marjorie Risman, Mary McCoy, Kevin Trindade, Liming Qu, Marina Cuchel, Jeffrey T. Billheimer, Daniel J. Rader

    Publicado em 2015
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  7. 7
    Genetic testing in dyslipidemia: A scientific statement from the National Lipid Association

    Genetic testing in dyslipidemia: A scientific statement from the National Lipid Association por Emily Brown, Amy C. Sturm, Marina Cuchel, Lynne T. Braun, P. Barton Duell, James Underberg, Terry A. Jacobson, Robert A. Hegele

    Publicado em 2020
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  8. 8
    Long-term experience with lomitapide treatment in patients with homozygous familial hypercholesterolemia: Over ten years of efficacy and safety data

    Long-term experience with lomitapide treatment in patients with homozygous familial hypercholesterolemia: Over ten years of efficacy and safety data por Marcello Arca, Laura D’Erasmo, Marina Cuchel, Dirk Blom, Jaimini Cegla, P. Barton Duell, Raul D. Santos, Sallyann L. O’Brien

    Publicado em 2025
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  9. 9
    Microsomal Triglyceride Transfer Protein Transfers and Determines Plasma Concentrations of Ceramide and Sphingomyelin but Not Glycosylceramide

    Microsomal Triglyceride Transfer Protein Transfers and Determines Plasma Concentrations of Ceramide and Sphingomyelin but Not Glycosylceramide por Jahangir Iqbal, Meghan T. Walsh, Samar M. Hammad, Marina Cuchel, Patrizia Tarugi, Robert A. Hegele, Nicholas O. Davidson, Daniel J. Rader, Richard L. Klein, M. Mahmood Hussain

    Publicado em 2015
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  10. 10
    Inhibition of Microsomal Triglyceride Transfer Protein in Familial Hypercholesterolemia

    Inhibition of Microsomal Triglyceride Transfer Protein in Familial Hypercholesterolemia por Marina Cuchel, LeAnne T. Bloedon, Philippe Szapary, Daniel M. Kolansky, Megan L. Wolfe, Antoine Sarkis, John S. Millar, Katsunori Ikewaki, Evan S. Siegelman, Richard E. Gregg, Daniel J. Rader

    Publicado em 2007
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  11. 11
    ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia—Brief Report

    ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia—Brief Report por Laurens F. Reeskamp, John S. Millar, WU Li-ya, Hans Jansen, Dewi van Harskamp, Henk Schierbeek, Daniel A. Gipe, Daniel J. Rader, Geesje M. Dallinga‐Thie, G. Kees Hovingh, Marina Cuchel

    Publicado em 2021
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  12. 12
    Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

    Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis por Amit Khera, Marina Cuchel, Margarita de la Llera-Moya, Amrith Rodrigues, Megan F. Burke, Kashif Jafri, Benjamin French, Julie A. Phillips, Megan Mucksavage, Robert L. Wilensky, Emile R. Mohler, George H. Rothblat, Daniel J. Rader

    Publicado em 2011
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  13. 13
    Reduced β-Cell Secretory Capacity in Pancreatic-Insufficient, but Not Pancreatic-Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance

    Reduced β-Cell Secretory Capacity in Pancreatic-Insufficient, but Not Pancreatic-Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance por Saba Sheikh, Lalitha Gudipaty, Diva D. De León, Denis Hadjiliadis, Christina Kubrak, Nora K. Rosenfeld, Sarah C. Nyirjesy, Amy J. Peleckis, Saloni Malik, Darko Stefanovski, Marina Cuchel, Ronald C. Rubenstein, Andrea Kelly, Michael R. Rickels

    Publicado em 2016
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  14. 14
    Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia

    Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia por Dirk Blom, Maurizio Averna, Emma A. Meagher, Hendrik du Toit Theron, Cesare R. Sirtori, Robert A. Hegele, Prediman K. Shah, Daniel Gaudet, Claudia Stefanutti, Giovanni Battista Vigna, Dominique Larrey, LeAnne T. Bloedon, Pamela Foulds, Daniel J. Rader, Marina Cuchel

    Publicado em 2017
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  15. 15
    Infusion of Reconstituted High‐Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial

    Infusion of Reconstituted High‐Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial por Pierluigi Tricoci, Denise D’Andrea, Paul A. Gurbel, Zhenling Yao, Marina Cuchel, Brion Winston, Robert J. Schott, Robert Weiss, Michael A. Blazing, Louis Cannon, Alison Bailey, Dominick J. Angiolillo, Andreas Gille, Charles L. Shear, Samuel D. Wright, John H. Alexander

    Publicado em 2015
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  16. 16
    Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress

    Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress por Ying Liu, Donna Conlon, Xin Bi, Katherine J. Slovik, Jianting Shi, Hailey I. Edelstein, John S. Millar, Ali Javaheri, Marina Cuchel, Evanthia Pashos, Jahangir Iqbal, M. Mahmood Hussain, Robert A. Hegele, Wenli Yang, Stephen A. Duncan, Daniel J. Rader, Edward E. Morrisey

    Publicado em 2017
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  17. 17
    ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia

    ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia por Daniel Gaudet, Daniel A. Gipe, Robert Pordy, Zahid Ahmad, Marina Cuchel, Prediman K. Shah, Kuang-Yuh Chyu, William J. Sasiela, Kuo‐Chen Chan, Diane Brisson, Étienne Khoury, Poulabi Banerjee, Viktoria Gusarova, Jesper Gromada, Neil Stahl, George D. Yancopoulos, G. Kees Hovingh

    Publicado em 2017
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  18. 18
    The lipid-lowering effects of lomitapide are unaffected by adjunctive apheresis in patients with homozygous familial hypercholesterolaemia – A post-hoc analysis of a Phase 3, single-arm, open-label trial

    The lipid-lowering effects of lomitapide are unaffected by adjunctive apheresis in patients with homozygous familial hypercholesterolaemia – A post-hoc analysis of a Phase 3, singl... por Claudia Stefanutti, Dirk Blom, Maurizio Averna, Emma A. Meagher, Hendrik d Theron, A. David Marais, Robert A. Hegele, Cesare R. Sirtori, Prediman K. Shah, Daniel Gaudet, Giovanni Battista Vigna, Bruce S. Sachais, S. Di Giacomo, Anna M.E. Du Plessis, LeAnne T. Bloedon, John Balser, Daniel J. Rader, Marina Cuchel

    Publicado em 2015
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  19. 19
    Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

    Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study por Marina Cuchel, Emma A. Meagher, Hendrik du Toit Theron, Dirk Blom, A. David Marais, Robert A. Hegele, Maurizio Averna, Cesare R. Sirtori, Prediman K. Shah, Daniel Gaudet, Claudia Stefanutti, Giovanni Battista Vigna, Anna ME Du Plessis, Kathleen J. Propert, William J. Sasiela, LeAnne T. Bloedon, Daniel J. Rader

    Publicado em 2012
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  20. 20
    Functional Analysis and Transcriptomic Profiling of iPSC-Derived Macrophages and Their Application in Modeling Mendelian Disease

    Functional Analysis and Transcriptomic Profiling of iPSC-Derived Macrophages and Their Application in Modeling Mendelian Disease por Hanrui Zhang, Chenyi Xue, Rachana Shah, Kate Bermingham, Christine Hinkle, Wenjun Li, Amrith Rodrigues, Jennifer Tabita‐Martinez, John S. Millar, Marina Cuchel, Evanthia Pashos, Ying Liu, Ruilan Yan, Wenli Yang, Sager J. Gosai, Daniel VanDorn, Stella T. Chou, Brian D. Gregory, Edward E. Morrisey, Mingyao Li, Daniel J. Rader, Muredach P. Reilly

    Publicado em 2015
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