Kết quả tìm kiếm - Marie O’Farrell
- Đang hiển thị 1 - 12 kết quả của 12
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FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models Bằng Marie O’Farrell, G M Duke, R. Webster Crowley, Douglas Buckley, Eduardo B. Martins, Dipankar Bhattacharya, Scott L. Friedman, George Kemble
Được phát hành 2022Artigo -
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Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification Bằng Samuel E. DePrimo, Lily Wong, Deepak Khatry, Susan L Nicholas, William C. Manning, Beverly D. Smolich, Anne-Marie O’Farrell, Julie M. Cherrington
Được phát hành 2003Artigo -
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Denifanstat for the treatment of metabolic dysfunction-associated steatohepatitis: a multicentre, double-blind, randomised, placebo-controlled, phase 2b trial Bằng Rohit Loomba, Pierre Bédossa, Katharine Grimmer, George Kemble, Eduardo B. Martins, William McCulloch, Marie O’Farrell, Wen-Wei Tsai, Jose Cobiella, Eric Lawitz, Madhavi Rudraraju, Stephen A. Harrison
Được phát hành 2024Artigo -
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Therapeutic efficacy of FASN inhibition in preclinical models of HCC Bằng Haichuan Wang, Yi Zhou, Hongwei Xu, Xue Wang, Yi Zhang, Runze Shang, Marie O’Farrell, Stephanie Roessler, Carsten Sticht, Andreas Stahl, Matthias Evert, Diego F. Calvisi, Yong Zeng, Xin Chen
Được phát hành 2022Artigo -
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p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model Bằng Hoi Yee Chow, Adrian M. Jubb, Jennifer N. Koch, Zahara M. Jaffer, Dina Stepanova, David A. Campbell, Sergio G. Durón, Marie O’Farrell, Kathy Q. Cai, Andres J. Klein–Szanto, J. Silvio Gutkind, Klaus P. Hoeflich, Jonathan Chernoff
Được phát hành 2012Artigo -
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SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo Bằng Anne-Marie O'Farrell, Tinya J. Abrams, Helene A. Yuen, Theresa J. Ngai, Sharianne G. Louie, Kevin Yee, Lily Wong, Weiru Hong, Leslie B. Lee, Ajia Town, Beverly D. Smolich, William C. Manning, Lesley Murray, Michael C. Heinrich, Julie M. Cherrington
Được phát hành 2003Artigo -
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First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors Bằng Gerald S. Falchook, Jeffrey R. Infante, Hendrik‐Tobias Arkenau, Manish R. Patel, Emma Dean, Erkut Borazanci, Andrew Brenner, Natalie Cook, Juanita Lopez, Shubham Pant, Arthur E. Frankel, Peter Schmid, Kathleen N. Moore, William McCulloch, Katharine Grimmer, Marie O’Farrell, George Kemble, Howard A. Burris
Được phát hành 2021Artigo -
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SU5416, a small molecule tyrosine kinase receptor inhibitor, has biologic activity in patients with refractory acute myeloid leukemia or myelodysplastic syndromes Bằng Francis J. Giles, Alison Stopeck, Lewis R. Silverman, Jeffrey E. Lancet, Maureen Cooper, Alison L. Hannah, Julie M. Cherrington, Anne-Marie O'Farrell, Helene A. Yuen, Sharianne G. Louie, Weiru Hong, Jorge E. Cortés, Srđan Verstovšek, Maher Albitar, Susan O’Brien, Hagop M. Kantarjian, Judith E. Karp
Được phát hành 2003Artigo -
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TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial Bằng Rohit Loomba, Rizwana Mohseni, Kathryn Jean Lucas, Julio Gutiérrez, Robert G. Perry, James F. Trotter, Robert S. Rahimi, Stephen A. Harrison, Veeral Ajmera, Jeffrey D. Wayne, Marie O’Farrell, William McCulloch, Katharine Grimmer, Mary E. Rinella, Vincent Wai‐Sun Wong, Vlad Ratziu, Gregory J. Gores, Brent A. Neuschwander‐Tetri, George Kemble
Được phát hành 2021Artigo -
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Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use Bằng Anna Worthmann, Julius Ridder, Sharlaine Piel, Ioannis Evangelakos, Melina Musfeldt, Hannah Voß, Marie O’Farrell, Alexander W. Fischer, Sangeeta Adak, Monica Sundd, Hasibullah Siffeti, Friederike Haumann, Katja Kloth, Tatjana Bierhals, Markus Heine, Paul Pertzborn, Mira Pauly, Julia-Josefine Scholz, Suman Kundu, Marceline M. Fuh, Axel Neu, Klaus Tödter, Maja Hempel, Uwe Knippschild, Clay F. Semenkovich, Hartmut Schlüter, Jöerg Heeren, Ludger Scheja, Christian Kubisch, Christian Schlein
Được phát hành 2024Artigo
Công cụ tìm kiếm:
Các môn học liên quan
Medicine
Biology
Internal medicine
Cancer research
Biochemistry
Cancer
Pharmacology
Chemistry
Disease
Fatty acid synthase
Fatty liver
Gene
Immunology
Pathology
Alternative medicine
Cell biology
Colorectal cancer
Enzyme
Fibrosis
Fms-Like Tyrosine Kinase 3
Gastroenterology
Leukemia
Mutation
Myeloid leukemia
Nonalcoholic fatty liver disease
Nonalcoholic steatohepatitis
PI3K/AKT/mTOR pathway
Placebo
Protein kinase B
Signal transduction