Risultati della ricerca - Margaret Soucheray

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  1. 1
    Intratumoral Heterogeneity in <i>EGFR</i>-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition

    Intratumoral Heterogeneity in <i>EGFR</i>-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition di Margaret Soucheray, Marzia Capelletti, Inés Pulido, Yanan Kuang, Cloud P. Paweletz, Jeffrey H. Becker, Eiki Kikuchi, Chunxiao Xu, Tarun B. Patel, Fátima Al‐Shahrour, Julián Carretero, Kwok‐Kin Wong, Pasi A. Jänne, Geoffrey I. Shapiro, Takeshi Shimamura

    Pubblicazione 2015
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  2. 2
    Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non–Small Cell Lung Cancer

    Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non–Small Cell Lung Cancer di Takeshi Shimamura, Zhao Chen, Margaret Soucheray, Julián Carretero, Eiki Kikuchi, Jeremy H. Tchaicha, Yandi Gao, Katherine A. Cheng, Travis J. Cohoon, Jun Qi, Esra A. Akbay, Alec C. Kimmelman, Andrew L. Kung, James E. Bradner, Kwok‐Kin Wong

    Pubblicazione 2013
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  3. 3
    The functional landscape of the human phosphoproteome

    The functional landscape of the human phosphoproteome di David Ochoa, Andrew F. Jarnuczak, Cristina Viéitez, Maja Gehre, Margaret Soucheray, André Mateus, Askar A. Kleefeldt, Anthony D. Hill, Luz García‐Alonso, Frank Stein, Nevan J. Krogan, Mikhail M. Savitski, Danielle L. Swaney, Juan Antonio Vizcaíno, Kyung‐Min Noh, Pedro Beltrão

    Pubblicazione 2019
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  4. 4
    Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer

    Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer di Oddbjørn Straume, Takeshi Shimamura, Michael Lampa, Julián Carretero, Anne M. Øyan, Di Jia, Christa L. Borgman, Margaret Soucheray, Sean R. Downing, Sarah M. Short, Soo-Young Kang, Souming Wang, Liang Chen, Karin Collett, Ingeborg Bachmann, Kwok‐Kin Wong, Geoffrey I. Shapiro, Karl H. Kalland, Judah Folkman, Randolph S. Watnick, Lars A. Akslen, George N. Naumov

    Pubblicazione 2012
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  5. 5
    Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

    Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant di Ann‐Kathrin Reuschl, Lucy Thorne, Lorena Zuliani‐Alvarez, Mehdi Bouhaddou, Kirsten Obernier, Joseph Hiatt, Margaret Soucheray, Jane Turner, Jacqueline M. Fabius, Gina T. Nguyen, Danielle L. Swaney, Romel Rosales, Kris M. White, Pablo Avilés, Ilsa T. Kirby, James E. Melnyk, Ying Shi, Ziyang Zhang, Kevan M. Shokat, Adolfo García‐Sastre, Clare Jolly, Greg J. Towers, Nevan J. Krogan

    Pubblicazione 2021
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  6. 6
    CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC

    CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC di Jeffrey H. Becker, Yandi Gao, Margaret Soucheray, Inés Pulido, Eiki Kikuchi, María L. Rodríguez, Rutu Gandhi, Aránzazu Lafuente-Sanchis, Miguel Aupí, Javier Alcácer Fernández-Coronado, Paloma Martín-Martorell, Antonio Cremades, José M. Galbis, Javier Alcácer, Camilla L. Christensen, Patricia Simms, Ashley Hess, Hajime Asahina, Michael Kahle, Fátima Al‐Shahrour, Jeffrey A. Borgia, Agustín Lahoz, Amelia Insa, Óscar Juan, Pasi A. Jänne, Kwok‐Kin Wong, Julián Carretero, Takeshi Shimamura

    Pubblicazione 2019
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  7. 7
    A protein interaction landscape of breast cancer

    A protein interaction landscape of breast cancer di Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, Maya Modak, Margaret Soucheray, Michael McGregor, Patrick C. O’Leary, Denise M. Wolf, Erica Stevenson, Tzeh Keong Foo, D. Mitchell, Kari A. Herrington, Denise P. Muñoz, Beril Tutuncuoglu, Kuei‐Ho Chen, Fan Zheng, Jason F. Kreisberg, Morgan E. Diolaiti, John D. Gordan, Jean-Philippe Coppé, Danielle L. Swaney, Bing Xia, Laura van ‘t Veer, Alan Ashworth, Trey Ideker, Nevan J. Krogan

    Pubblicazione 2021
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  8. 8
    Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors

    Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors di Esra A. Akbay, Shohei Koyama, Julián Carretero, Abigail Altabef, Jeremy H. Tchaicha, Camilla L. Christensen, Oliver R. Mikse, Andrew D. Cherniack, Ellen M. Beauchamp, Trevor J. Pugh, Matthew D. Wilkerson, Peter E. Fecci, Mohit Butaney, Jacob B. Reibel, Margaret Soucheray, Travis J. Cohoon, Pasi A. Jänne, Matthew Meyerson, D. Neil Hayes, Geoffrey I. Shapiro, Takeshi Shimamura, Lynette M. Sholl, Scott J. Rodig, Gordon J. Freeman, Peter S. Hammerman, Glenn Dranoff, Kwok‐Kin Wong

    Pubblicazione 2013
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  9. 9
    A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity

    A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity di Danielle L. Swaney, Dana J. Ramms, Zhiyong Wang, Jisoo Park, Yusuke Goto, Margaret Soucheray, Neil E. Bhola, Kyumin Kim, Fan Zheng, Yan Zeng, Michael McGregor, Kari A. Herrington, Rachel A. O’Keefe, Nan Jin, Nathan K. VanLandingham, Helene Foussard, John Von Dollen, Mehdi Bouhaddou, David Jimenez‐Morales, Kirsten Obernier, Jason F. Kreisberg, Minkyu Kim, Daniel E. Johnson, Natalia Jura, Jennifer R. Grandis, J. Silvio Gutkind, Trey Ideker, Nevan J. Krogan

    Pubblicazione 2021
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  10. 10
    Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

    Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant di Lucy Thorne, Mehdi Bouhaddou, Ann‐Kathrin Reuschl, Lorena Zuliani‐Alvarez, Benjamin J. Polacco, Adrian Pelin, Jyoti Batra, Matthew V.X. Whelan, Manisha R. Ummadi, Ajda Rojc, Jane Turner, Kirsten Obernier, Hannes Braberg, Margaret Soucheray, Alicia Richards, Kuei‐Ho Chen, Bhavya Harjai, Danish Memon, Myra Hosmillo, Joseph Hiatt, Aminu S. Jahun, Ian Goodfellow, Jacqueline M. Fabius, Kevan M. Shokat, Natalia Jura, Klim Verba, Mahdad Noursadeghi, Pedro Beltrão, Danielle L. Swaney, Adolfo García‐Sastre, Clare Jolly, Greg J. Towers, Nevan J. Krogan

    Pubblicazione 2021
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  11. 11
    STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment

    STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment di Shohei Koyama, Esra A. Akbay, Yvonne Y. Li, Amir Reza Aref, Ferdinandos Skoulidis, Grit S. Herter-Sprie, Kevin A. Buczkowski, Yan Liu, Mark M. Awad, Warren L. Denning, Lixia Diao, Jing Wang, Edwin R. Parra-Cuentas, Ignacio I. Wistuba, Margaret Soucheray, Tran C. Thai, Hajime Asahina, Shunsuke Kitajima, Abigail Altabef, Jillian D. Cavanaugh, Kevin Rhee, Peng Gao, Haikuo Zhang, Peter E. Fecci, Takeshi Shimamura, Matthew D. Hellmann, John V. Heymach, F. Stephen Hodi, Gordon J. Freeman, David A. Barbie, Glenn Dranoff, Peter S. Hammerman, Kwok‐Kin Wong

    Pubblicazione 2016
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  12. 12
    Evolution of enhanced innate immune evasion by SARS-CoV-2

    Evolution of enhanced innate immune evasion by SARS-CoV-2 di Lucy Thorne, Mehdi Bouhaddou, Ann‐Kathrin Reuschl, Lorena Zuliani‐Alvarez, Benjamin J. Polacco, Adrian Pelin, Jyoti Batra, Matthew V.X. Whelan, Myra Hosmillo, Andrea Fossati, Roberta Ragazzini, Irwin Jungreis, Manisha R. Ummadi, Ajda Rojc, Jane Turner, Marie L. Bischof, Kirsten Obernier, Hannes Braberg, Margaret Soucheray, Alicia Richards, Kuei‐Ho Chen, Bhavya Harjai, Danish Memon, Joseph Hiatt, Romel Rosales, Briana L. McGovern, Aminu S. Jahun, Jacqueline M. Fabius, Kris M. White, Ian Goodfellow, Yasu Takeuchi, Paola Bonfanti, Kevan M. Shokat, Natalia Jura, Klim Verba, Mahdad Noursadeghi, Pedro Beltrão, Manolis Kellis, Danielle L. Swaney, Adolfo García‐Sastre, Clare Jolly, Greg J. Towers, Nevan J. Krogan

    Pubblicazione 2021
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  13. 13
    Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis

    Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis di Thomas Kehrer, Anastasija Čupić, Chengjin Ye, Soner Yildiz, Mehdi Bouhaddou, Nicholas A. Crossland, Erika A. Barrall, Phillip Cohen, Anna E. Tseng, Tolga Çağatay, Raveen Rathnasinghe, Daniel Flores, Sonia Jangra, Fahmida Alam, Ignacio Mena, Sadaf Aslam, Anjali Saqi, Magdalena Rutkowska, Manisha R. Ummadi, Giuseppe Pisanelli, R. Blake Richardson, Ethan C. Veit, Jacqueline M. Fabius, Margaret Soucheray, Benjamin J. Polacco, Baran Ak, Arturo Marín, Matthew J. Evans, Danielle L. Swaney, Ana S. González-Reiche, Emilia Mia Sordillo, Harm van Bakel, Viviana Simon, Lorena Zuliani‐Alvarez, Beatriz M. A. Fontoura, Brad R. Rosenberg, Nevan J. Krogan, Luis Martínez‐Sobrido, Adolfo García‐Sastre, Lisa Miorin

    Pubblicazione 2023
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  14. 14
    Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets

    Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets di Kelsey M. Haas, Michael McGregor, Mehdi Bouhaddou, Benjamin J. Polacco, Eun‐Young Kim, Thông Nguyen, Billy W. Newton, Matthew Urbanowski, Hee Jin Kim, Michael A. P. Williams, Veronica V. Rezelj, Alexandra Hardy, Andrea Fossati, Erica Stevenson, Ellie Sukerman, Tiffany Kim, Sudhir Penugonda, Elena Moreno, Hannes Braberg, Yuan Zhou, Giorgi Metreveli, Bhavya Harjai, Tia A. Tummino, James E. Melnyk, Margaret Soucheray, Jyoti Batra, Lars Pache, Laura Martin‐Sancho, Jared Carlson-Stevermer, Alexander S. Jureka, Christopher F. Basler, Kevan M. Shokat, Brian K. Shoichet, Leah P. Shriver, Jeffrey R. Johnson, Megan L. Shaw, Sumit K. Chanda, Dan M. Roden, Tonia C. Carter, Leah C. Kottyan, Rex L. Chisholm, Jennifer A. Pacheco, Maureen E. Smith, Steven J. Schrodi, Randy A. Albrecht, Marco Vignuzzi, Lorena Zuliani‐Alvarez, Danielle L. Swaney, Manon Eckhardt, Steven M. Wolinsky, Kris M. White, Judd F. Hultquist, Robyn M. Kaake, Adolfo Garcı́a-Sastre, Nevan J. Krogan

    Pubblicazione 2023
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  15. 15
    The Global Phosphorylation Landscape of SARS-CoV-2 Infection

    The Global Phosphorylation Landscape of SARS-CoV-2 Infection di Mehdi Bouhaddou, Danish Memon, Bjoern Meyer, Kris M. White, Veronica V. Rezelj, Miguel Marrero, Benjamin J. Polacco, James E. Melnyk, Svenja Ulferts, Robyn M. Kaake, Jyoti Batra, Alicia Richards, Erica Stevenson, David E. Gordon, Ajda Rojc, Kirsten Obernier, Jacqueline M. Fabius, Margaret Soucheray, Lisa Miorin, Elena Moreno, Cassandra Koh, Quang Tran, Alexandra Hardy, Rémy Robinot, Thomas Vallet, Benjamin E. Nilsson-Payant, Claudia Hernández-Armenta, Alistair S. Dunham, Sebastian Weigang, Julian Knerr, Maya Modak, Diego Quintero, Yuan Zhou, Aurélien Dugourd, Alberto Valdeolivas, Trupti Patil, Qiongyu Li, Ruth Hüttenhain, Merve Çakır, Monita Muralidharan, Minkyu Kim, Gwendolyn Μ. Jang, Beril Tutuncuoglu, Joseph Hiatt, Jeffrey Guo, Jiewei Xu, Sophia Bouhaddou, Christopher J.P. Mathy, Anna Gaulton, Emma J. Manners, Eloy Félix, Ying Shi, Marisa Goff, Jean K. Lim, Timothy P. McBride, Michael C. O’Neal, Yiming Cai, Jason C. Chang, David Broadhurst, Saker Klippsten, Emmie de Wit, Andrew R. Leach, Tanja Kortemme, Brian K. Shoichet, Mélanie Ott, Julio Sáez-Rodríguez, Benjamin R. tenOever, R. Dyche Mullins, Elizabeth R. Fischer, Georg Kochs, Robert Grosse, Adolfo García‐Sastre, Marco Vignuzzi, Jeffrey R. Johnson, Kevan M. Shokat, Danielle L. Swaney, Pedro Beltrão, Nevan J. Krogan

    Pubblicazione 2020
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  16. 16
    SARS-CoV-2 variants evolve convergent strategies to remodel the host response

    SARS-CoV-2 variants evolve convergent strategies to remodel the host response di Mehdi Bouhaddou, Ann‐Kathrin Reuschl, Benjamin J. Polacco, Lucy Thorne, Manisha R. Ummadi, Chengjin Ye, Romel Rosales, Adrian Pelin, Jyoti Batra, Gwendolyn Μ. Jang, Jiewei Xu, Jack M. Moen, Alicia Richards, Yuan Zhou, Bhavya Harjai, Erica Stevenson, Ajda Rojc, Roberta Ragazzini, Matthew V.X. Whelan, Wilhelm Furnon, Giuditta De Lorenzo, Vanessa M. Cowton, Abdullah M. Syed, Alison Ciling, Noa Deutsch, Daniel Pirak, Giulia Dowgier, Dejan Mesner, Jane Turner, Briana L. McGovern, Myosotys Rodriguez, Rocio Leiva-Rebollo, Alistair S. Dunham, Xiaofang Zhong, Manon Eckhardt, Andrea Fossati, Nicholas Liotta, Thomas Kehrer, Anastasija Čupić, Magdalena Rutkowska, Ignacio Mena, Sadaf Aslam, Alyssa Hoffert, Helene Foussard, Charles Ochieng’ Olwal, Weiqing Huang, Thomas P. Zwaka, John Pham, Molly Lyons, Laura K. Donohue, Aliesha Griffin, Rebecca Nugent, Kevin Holden, Robert Deans, Pablo Avilés, José A. López-Martín, José Jimeno, Kirsten Obernier, Jacqueline M. Fabius, Margaret Soucheray, Ruth Hüttenhain, Irwin Jungreis, Manolis Kellis, Ignacia Echeverria, Kliment A. Verba, Paola Bonfanti, Pedro Beltrão, Roded Sharan, Jennifer A. Doudna, Luis Martínez‐Sobrido, Arvind H. Patel, Massimo Palmarini, Lisa Miorin, Kris M. White, Danielle L. Swaney, Adolfo García‐Sastre, Clare Jolly, Lorena Zuliani‐Alvarez, Greg J. Towers, Nevan J. Krogan

    Pubblicazione 2023
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  17. 17
    A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

    A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing di David E. Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Matthew J. O’Meara, Jeffrey Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Hüttenhain, Robyn M. Kaake, Alicia Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, Kelsey M. Haas, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J. Polacco, Hannes Braberg, Jacqueline M. Fabius, Manon Eckhardt, Margaret Soucheray, Melanie J. Bennett, Merve Çakır, Michael McGregor, Qiongyu Li, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ilsa T. Kirby, James E. Melnyk, John S. Chorba, Kevin Lou, Shizhong Dai, Wenqi Shen, Ying Shi, Ziyang Zhang, Inigo Barrio‐Hernandez, Danish Memon, Claudia Hernández-Armenta, Christopher J.P. Mathy, Tina Perica, Kala Bharath Pilla, Sai J. Ganesan, Daniel J. Saltzberg, Ramachandran Rakesh, Xi Liu, Sara Brin Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, José Liboy-Lugo, Yizhu Lin, Stephanie A. Wankowicz, Markus‐Frederik Bohn, Phillip P. Sharp, Raphael Trenker, Janet M. Young, Devin A. Cavero, Jonathan R. Hiatt, Theodore L. Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, Ferdinand Roesch, Thomas Vallet, Bjoern Meyer, Kris M. White, Lisa Miorin, Oren S. Rosenberg, Kliment A. Verba, David A. Agard, Mélanie Ott, Michael Emerman, Davide Ruggero, Adolfo García‐Sastre, Natalia Jura, Mark von Zastrow, Jack Taunton, Alan Ashworth, Olivier Schwartz, Marco Vignuzzi, Christophe d’Enfert, Shaeri Mukherjee, Matthew P. Jacobson, Harmit S. Malik, Danica Galonić Fujimori, Trey Ideker, Charles S. Craik, Stephen N. Floor, James S. Fraser, John D. Gross, Andrej Šali, Tanja Kortemme, Pedro Beltrão, Kevan M. Shokat, Brian K. Shoichet, Nevan J. Krogan

    Pubblicazione 2020
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  18. 18
    Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

    Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms di David E. Gordon, Joseph Hiatt, Mehdi Bouhaddou, Veronica V. Rezelj, Svenja Ulferts, Hannes Braberg, Alexander S. Jureka, Kirsten Obernier, Jeffrey Guo, Jyoti Batra, Robyn M. Kaake, Andrew R. Weckstein, Tristan W. Owens, Meghna Gupta, Sergei Pourmal, Erron W. Titus, Merve Çakır, Margaret Soucheray, Michael McGregor, Zeynep Cakir, Gwendolyn Μ. Jang, Matthew J. O’Meara, Tia A. Tummino, Ziyang Zhang, Helene Foussard, Ajda Rojc, Yuan Zhou, Dmitry Kuchenov, Ruth Hüttenhain, Jiewei Xu, Manon Eckhardt, Danielle L. Swaney, Jacqueline M. Fabius, Manisha R. Ummadi, Beril Tutuncuoglu, Ujjwal Rathore, Maya Modak, Paige Haas, Kelsey M. Haas, Zun Zar Chi Naing, Ernst H. Pulido, Ying Shi, Inigo Barrio‐Hernandez, Danish Memon, Eirini Petsalaki, Alistair S. Dunham, Miguel Marrero, David F. Burke, Cassandra Koh, Thomas Vallet, Jesus A. Silvas, Caleigh M. Azumaya, Christian B. Billesbølle, Axel F. Brilot, Melody G. Campbell, Amy Diallo, Miles Sasha Dickinson, Devan Diwanji, Nadia Herrera, Nick Hoppe, Huong T. Kratochvil, Yanxin Liu, Gregory E. Merz, Michelle Moritz, Henry C. Nguyen, Carlos Nowotny, Cristina Puchades, Alexandrea N. Rizo, Ursula Schulze‐Gahmen, Amber M. Smith, Ming Sun, I.D. Young, Jianhua Zhao, Daniel Asarnow, J.T. Biel, Alisa Bowen, Julian R. Braxton, Jen Chen, Cynthia M. Chio, Un Seng Chio, Ishan Deshpande, Loan Doan, Bryan Faust, Sebastián Flores, Mingliang Jin, Kate Kim, Victor L. Lam, Fei Li, Junrui Li, Yen-Li Li, Yang Li, Xi Liu, Megan Lo, Kyle E. Lopez, Arthur A. Melo, Frank R. Moss, Phuong Nguyen, Joana Paulino, Komal Ishwar Pawar, Jessica K. Peters

    Pubblicazione 2020
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