检索结果 - Marcel Doerflinger

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  1. 1
    <i>Mycobacterium tuberculosis</i>: Rewiring host cell signaling to promote infection

    <i>Mycobacterium tuberculosis</i>: Rewiring host cell signaling to promote infection 由 Michael D. Stutz, Michelle P. Clark, Marcel Doerflinger, Marc Pellegrini

    出版 2017
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  2. 2
    Programmed cell death: the pathways to severe COVID-19?

    Programmed cell death: the pathways to severe COVID-19? 由 Stefanie M. Bader, James P. Cooney, Marc Pellegrini, Marcel Doerflinger

    出版 2022
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  3. 3
    CRISPR/Cas9-The ultimate weapon to battle infectious diseases?

    CRISPR/Cas9-The ultimate weapon to battle infectious diseases? 由 Marcel Doerflinger, Wasan Forsyth, Gregor Ebert, Marc Pellegrini, Marco J. Herold

    出版 2016
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  4. 4
    Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim

    Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim 由 B. Marshall, Hamsa Puthalakath, Sofia Caria, Srishti Chugh, Marcel Doerflinger, Peter M. Colman, Marc Kvansakul

    出版 2015
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  5. 5
    Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo

    Necroptosis does not drive disease pathogenesis in a mouse infective model of SARS-CoV-2 in vivo 由 Stefanie M. Bader, James P. Cooney, Reet Bhandari, Liana Mackiewicz, Merle Dayton, Dylan Sheerin, Smitha R. Georgy, James M. Murphy, Kathryn Davidson, Cody Allison, Marc Pellegrini, Marcel Doerflinger

    出版 2024
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  6. 6
    DR5 and caspase-8 are dispensable in ER stress-induced apoptosis

    DR5 and caspase-8 are dispensable in ER stress-induced apoptosis 由 Jason Glab, Marcel Doerflinger, Christina Nedeva, Irvin Jose, George W. Mbogo, James C. Paton, Adrienne W. Paton, Andrew J. Kueh, Marco J. Herold, David C.S. Huang, David Segal, Gabriella Brumatti, Hamsa Puthalakath

    出版 2017
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  7. 7
    IL-1β drives SARS-CoV-2-induced disease independently of the inflammasome and pyroptosis signalling

    IL-1β drives SARS-CoV-2-induced disease independently of the inflammasome and pyroptosis signalling 由 Stefanie M. Bader, L.R. Scherer, Jan Schaefer, James P. Cooney, Liana Mackiewicz, Merle Dayton, Smitha R. Georgy, Kathryn C. Davidson, Cody Allison, Marco J. Herold, Andreas Strasser, Marc Pellegrini, Marcel Doerflinger

    出版 2025
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  8. 8
    Macrophage and neutrophil death programs differentially confer resistance to tuberculosis

    Macrophage and neutrophil death programs differentially confer resistance to tuberculosis 由 Michael D. Stutz, Cody Allison, Samar Ojaimi, Simon Preston, Marcel Doerflinger, Philip Arandjelovic, Lachlan Whitehead, Stefanie M. Bader, Daniel Batey, Marie-Liesse Asselin-Labat, Marco J. Herold, Andreas Strasser, Nicholas P. West, Marc Pellegrini

    出版 2021
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  9. 9
    Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria

    Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria 由 Ann Ly, Yang Liao, Halina M. Pietrzak, Lisa J. Ioannidis, Tom Sidwell, Renee Gloury, Marcel Doerflinger, Tony Triglia, Raymond Z. Qin, Joanna R. Groom, Gabrielle T. Belz, Kim L. Good‐Jacobson, Wei Shi, Axel Kallies, Diana S. Hansen

    出版 2019
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  10. 10
    Venetoclax, alone and in combination with the BH3 mimetic S63845, depletes HIV-1 latently infected cells and delays rebound in humanized mice

    Venetoclax, alone and in combination with the BH3 mimetic S63845, depletes HIV-1 latently infected cells and delays rebound in humanized mice 由 Philip Arandjelovic, Youry Kim, James P. Cooney, Simon Preston, Marcel Doerflinger, James McMahon, Sarah Garner, Jennifer M. Zerbato, Michael Roche, Carolin Tumpach, Jesslyn Ong, Dylan Sheerin, Gordon K. Smyth, Jenny L. Anderson, Cody Allison, Sharon R. Lewin, Marc Pellegrini

    出版 2023
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  11. 11
    i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4

    i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4 由 Katherine Griffiths, Olan Dolezal, Benjamin Cao, Susan K. Nilsson, Heng B. See, Kevin D. G. Pfleger, Michael Roche, Paul R. Gorry, Andrew Pow, Katerina Viduka, Kevin Lim, Bernadine G.C. Lu, Denison H.C. Chang, Thomas A. Murray-Rust, Marc Kvansakul, Matthew A. Perugini, Con Dogovski, Marcel Doerflinger, Yuan Zhang, Kathy Parisi, Joanne L. Casey, Stewart D. Nuttall, Michael Foley

    出版 2016
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  12. 12
    SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates

    SARS-CoV-2 mouse adaptation selects virulence mutations that cause TNF-driven age-dependent severe disease with human correlates 由 Stefanie M. Bader, James P. Cooney, Dylan Sheerin, George Taiaroa, Leigh Harty, Kathryn Davidson, Liana Mackiewicz, Merle Dayton, Stephen Wilcox, Lachlan Whitehead, Kelly L. Rogers, Smitha R. Georgy, Anna K. Coussens, Samantha L. Grimley, Vincent Corbin, Miranda E. Pitt, Lachlan Coin, R. J. Pickering, Merlin C. Thomas, Cody Allison, Julie McAuley, Damian F. J. Purcell, Marcel Doerflinger, Marc Pellegrini

    出版 2023
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  13. 13
    Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

    Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection 由 Marcel Doerflinger, Yexuan Deng, Paul G. Whitney, Ranja Salvamoser, Sven Engel, Andrew J. Kueh, Lin Tai, Annabell Bachem, Elise Gressier, Niall D. Geoghegan, Stephen Wilcox, Kelly L. Rogers, Alexandra L. Garnham, Michael A. Dengler, Stefanie M. Bader, Gregor Ebert, Jaclyn S. Pearson, Dominic De Nardo, Nancy Wang, Chenying Yang, Milton Pereira, Clare Bryant, Richard A. Strugnell, James E. Vince, Marc Pellegrini, Andreas Strasser, Sammy Bedoui, Marco J. Herold

    出版 2020
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  14. 14
    Caspase‐8‐driven apoptotic and pyroptotic crosstalk causes cell death and <scp>IL</scp>‐1β release in X‐linked inhibitor of apoptosis (<scp>XIAP</scp>) deficiency

    Caspase‐8‐driven apoptotic and pyroptotic crosstalk causes cell death and <scp>IL</scp>‐1β release in X‐linked inhibitor of apoptosis (<scp>XIAP</scp>) deficiency 由 Sebastian Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P. Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien‐Hsiung Yu, Natasha Silke, Stephanie A. Conos, Daniel Frank, Daniel S. Simpson, James M. Murphy, Kate E. Lawlor, Jaclyn S. Pearson, John Silke, Marc Pellegrini, Marco J. Herold, Ivan K. H. Poon, Seth L. Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lanlan Geng, James E. Vince

    出版 2023
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  15. 15
    Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis From Contributing to Liver Pathologies

    Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis From Contributing to Liver Pathologies 由 Simon Preston, Michael D. Stutz, Cody Allison, Ueli Nachbur, Quentin Gouil, Bang M. Tran, Valérie Duvivier, Philip Arandjelovic, James P. Cooney, Liana Mackiewicz, Yanxiang Meng, Jan Schaefer, Stefanie M. Bader, Hongke Peng, Zina Valaydon, Pravin Rajasekaran, Charlie Jennison, Sash Lopaticki, Ann Farrell, Marno Ryan, Jess Howell, Catherine Croagh, Denuja Karunakaran, Carole Schuster-Klein, James M. Murphy, Theodora Fifis, Christopher Christophi, Elizabeth Vincan, Marnie E. Blewitt, Alexander Thompson, Justin A. Boddey, Marcel Doerflinger, Marc Pellegrini

    出版 2022
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  16. 16
    Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

    Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 由 Theresa Klemm, Gregor Ebert, Dale J. Calleja, Cody Allison, Lachlan W. Richardson, Jonathan P. Bernardini, Bernadine G.C. Lu, Nathan W. Kuchel, Christoph Grohmann, Y. Shibata, Zhong Yan Gan, James P. Cooney, Marcel Doerflinger, Amanda E. Au, T. Blackmore, Gerbrand J. van der Heden van Noort, Paul P. Geurink, Huib Ovaa, Janet Newman, Alan Riboldi‐Tunnicliffe, Peter E. Czabotar, Jeffrey P. Mitchell, Rebecca Feltham, Bernhard C. Lechtenberg, Kym N. Lowes, Grant Dewson, Marc Pellegrini, Guillaume Lessène, David Komander

    出版 2020
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  17. 17
    Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice

    Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice 由 Phillip Pymm, Amy Adair, Li‐Jin Chan, James P. Cooney, Francesca L. Mordant, Cody Allison, Ester López, Ebene R. Haycroft, Matthew T. O’Neill, Li Lynn Tan, Melanie H. Dietrich, Damien R. Drew, Marcel Doerflinger, Michael A. Dengler, Nichollas E. Scott, Adam K. Wheatley, Nicholas A. Gherardin, Hariprasad Venugopal, Deborah Cromer, Miles P. Davenport, R. J. Pickering, Dale I. Godfrey, Damian F. J. Purcell, Stephen J. Kent, Amy W. Chung, Kanta Subbarao, Marc Pellegrini, Alisa Glukhova, Wai‐Hong Tham

    出版 2021
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  18. 18
    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

    Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway 由 Daniel S. Simpson, Jiyi Pang, Ashley Weir, Isabella Y. Kong, Melanie Fritsch, Maryam Rashidi, James P. Cooney, Kathryn Davidson, Mary Speir, Tirta M. Djajawi, Sebastian Hughes, Liana Mackiewicz, Merle Dayton, Holly Anderton, Marcel Doerflinger, Yexuan Deng, Allan Shuai Huang, Stephanie A. Conos, Hazel Tye, Seong Hoong Chow, Arfatur Rahman, Raymond S. Norton, Thomas Naderer, Sandra E. Nicholson, Gaëtan Burgio, Si Ming Man, Joanna R. Groom, Marco J. Herold, Edwin D. Hawkins, Kate E. Lawlor, Andreas Strasser, John Silke, Marc Pellegrini, Hamid Kashkar, Rebecca Feltham, James E. Vince

    出版 2022
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  19. 19
    A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID

    A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID 由 Stefanie M. Bader, Dale J. Calleja, Shane M. Devine, Nathan W. Kuchel, Bernadine G.C. Lu, Xinyu Wu, Richard W. Birkinshaw, Reet Bhandari, Katie Loi, Rohan Volpe, Yelena Khakham, Amanda E. Au, T. Blackmore, Liana Mackiewicz, Merle Dayton, Jan Schaefer, L.R. Scherer, Angus T. Stock, James P. Cooney, Kael L. Schoffer, Ana Maluenda, Elizabeth A. Kleeman, Kathryn C. Davidson, Cody Allison, Gregor Ebert, Gong� Chen, Kasiram Katneni, Theresa Klemm, Ueli Nachbur, Smitha R. Georgy, Peter E. Czabotar, Anthony J. Hannan, Tracy L. Putoczki, Maria C. Tanzer, Marc Pellegrini, Bernhard C. Lechtenberg, Susan A. Charman, Melissa Call, Jeffrey P. Mitchell, Kym N. Lowes, Guillaume Lessène, Marcel Doerflinger, David Komander

    出版 2025
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