Search Results - Manu Anantpadma

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  1. 1
    Machine learning models identify molecules active against the Ebola virus in vitro

    Machine learning models identify molecules active against the Ebola virus in vitro by Sean Ekins, Joel S. Freundlich, Alex M. Clark, Manu Anantpadma, Robert A. Davey, Peter B. Madrid

    Published 2017
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  2. 2
    The Natural Product Eugenol Is an Inhibitor of the Ebola Virus In Vitro

    The Natural Product Eugenol Is an Inhibitor of the Ebola Virus In Vitro by Thomas R. Lane, Manu Anantpadma, Joel S. Freundlich, Robert A. Davey, Peter B. Madrid, Sean Ekins

    Published 2019
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  3. 3
    Machine learning models identify molecules active against the Ebola virus in vitro

    Machine learning models identify molecules active against the Ebola virus in vitro by Sean Ekins, Joel S. Freundlich, Alex M. Clark, Manu Anantpadma, Robert A. Davey, Peter B. Madrid

    Published 2015
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  4. 4
    Hepatitis C Virus NS2 Protein Serves as a Scaffold for Virus Assembly by Interacting with both Structural and Nonstructural Proteins

    Hepatitis C Virus NS2 Protein Serves as a Scaffold for Virus Assembly by Interacting with both Structural and Nonstructural Proteins by Yinghong Ma, Manu Anantpadma, Jennifer M. Timpe, Saravanabalaji Shanmugam, Sher M. Singh, Stanley M. Lemon, MinKyung Yi

    Published 2010
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  5. 5
    Identification of Ellagic Acid from Plant Rhodiola rosea L. as an Anti-Ebola Virus Entry Inhibitor

    Identification of Ellagic Acid from Plant Rhodiola rosea L. as an Anti-Ebola Virus Entry Inhibitor by Qinghua Cui, Ruikun Du, Manu Anantpadma, Adam Schafer, Lin Hou, Jingzhen Tian, Robert A. Davey, Han Cheng, Lijun Rong

    Published 2018
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  6. 6
    Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection

    Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection by Thomas R. Lane, Christopher Massey, Jason E. Comer, Manu Anantpadma, Joel S. Freundlich, Robert A. Davey, Peter B. Madrid, Sean Ekins

    Published 2019
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  7. 7
    Ebola Virus Bayesian Machine Learning Models Enable New in Vitro Leads

    Ebola Virus Bayesian Machine Learning Models Enable New in Vitro Leads by Manu Anantpadma, Thomas R. Lane, Kimberley M. Zorn, Mary A. Lingerfelt, Alex M. Clark, Joel S. Freundlich, Robert A. Davey, Peter B. Madrid, Sean Ekins

    Published 2019
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  8. 8
    Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses

    Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses by Priya Luthra, Jacinth Naidoo, Colette Pietzsch, Sampriti De, Sudip Khadka, Manu Anantpadma, Caroline G. Williams, Megan R. Edwards, Robert A. Davey, Alexander Bukreyev, Joseph M. Ready, Christopher F. Basler

    Published 2018
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  9. 9
    Recombinant Pichinde reporter virus as a safe and suitable surrogate for high-throughput antiviral screening against highly pathogenic arenaviruses

    Recombinant Pichinde reporter virus as a safe and suitable surrogate for high-throughput antiviral screening against highly pathogenic arenaviruses by Carolina Q. Sacramento, Ryan Bott, Qinfeng Huang, Brett Eaton, Elena Postnikova, Ahmad Jawad Sabir, Malaika D. Argade, Kiira Ratia, Manu Anantpadma, Paul R. Carlier, Hinh Ly, Yuying Liang, Lijun Rong

    Published 2025
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  10. 10
    Interferon-γ Inhibits Ebola Virus Infection

    Interferon-γ Inhibits Ebola Virus Infection by Bethany A. Rhein, Linda S. Powers, Kai J. Rogers, Manu Anantpadma, Brajesh K. Singh, Yasuteru Sakurai, Thomas Bair, Catherine L. Miller-Hunt, Patrick L. Sinn, Robert A. Davey, Martha M. Monick, Wendy Maury

    Published 2015
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  11. 11
    Treatment of blood with a pathogen reduction technology using ultraviolet light and riboflavin inactivates <scp>E</scp>bola virus in vitro

    Treatment of blood with a pathogen reduction technology using ultraviolet light and riboflavin inactivates <scp>E</scp>bola virus in vitro by P. Andrew, Heather F. Pidcoke, Shawn D. Keil, Hilary Staples, Manu Anantpadma, Ricardo E. Carrión, Robert A. Davey, Ashley Frazer‐Abel, Audra L. Taylor, Richard Gonzales, Jean L. Patterson, Raymond P. Goodrich

    Published 2016
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  12. 12
    Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry Inhibitors

    Large-Scale Screening and Identification of Novel Ebola Virus and Marburg Virus Entry Inhibitors by Manu Anantpadma, Jennifer Kouznetsova, Hang Wang, Ruili Huang, Andrey A. Kolokoltsov, Rajarshi Guha, Aaron Lindstrom, Olena Shtanko, Anton Simeonov, David J. Maloney, Wendy Maury, Douglas LaCount, Ajit Jadhav, Robert A. Davey

    Published 2016
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  13. 13
    Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State

    Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State by Dong-Hoon Chung, Jennifer E. Golden, Robert S. Adcock, Chad E. Schroeder, Yong‐Kyu Chu, Julie Sotsky, Daniel Cramer, Paula M. Chilton, Chisu Song, Manu Anantpadma, Robert A. Davey, Aminul Islam Prodhan, Xinmin Yin, Xiang Zhang

    Published 2016
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  14. 14
    An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions

    An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions by Daisy W. Leung, Dominika Borek, Priya Luthra, Jennifer M. Binning, Manu Anantpadma, Gai Liu, Ian B. Harvey, Zhaoming Su, Ariel Endlich-Frazier, Juanli Pan, Reed S. Shabman, Wah Chiu, Robert A. Davey, Zbyszek Otwinowski, Christopher F. Basler, Gaya K. Amarasinghe

    Published 2015
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  15. 15
    In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity

    In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity by Craig S. Brown, Michael S. Lee, Daisy W. Leung, Tianjiao Wang, Wei Xü, Priya Luthra, Manu Anantpadma, Reed S. Shabman, Lisa Melito, Karen S. MacMillan, Dominika Borek, Zbyszek Otwinowski, Parameshwaran Ramanan, Alisha Stubbs, Dayna S. Peterson, Jennifer M. Binning, Marco Tonelli, Mark A. Olson, Robert A. Davey, Joseph M. Ready, Christopher F. Basler, Gaya K. Amarasinghe

    Published 2014
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  16. 16
    Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication

    Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication by Jyoti Batra, Judd F. Hultquist, Dandan Liu, Olena Shtanko, John Von Dollen, Laura Satkamp, Gwendolyn Μ. Jang, Priya Luthra, Toni M. Schwarz, Gabriel I. Small, Eusondia Arnett, Manu Anantpadma, Ann Reyes, Daisy W. Leung, Robyn M. Kaake, Paige Haas, Carson B. Schmidt, Larry S. Schlesinger, Douglas LaCount, Robert A. Davey, Gaya K. Amarasinghe, Christopher F. Basler, Nevan J. Krogan

    Published 2018
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  17. 17
    Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates

    Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates by Kristen E. Pascal, Drew Dudgeon, John C. Trefry, Manu Anantpadma, Yasuteru Sakurai, Charles D. Murin, Hannah L. Turner, Jeanette Fairhurst, Marcela Torres, Ashique Rafique, Ying Yan, Ashok Badithe, Kevin Yu, Terra Potocky, Sandra L. Bixler, Taylor Chance, William D. Pratt, Franco Rossi, Joshua D. Shamblin, Suzanne E. Wollen-Roberts, Justine M. Zelko, Ricardo E. Carrión, Gabriella Worwa, Hilary Staples, Darya Burakov, Robert Babb, Gang Chen, Joel Martin, Tammy Huang, Karl J. Erlandson, Melissa Swope Willis, Kimberly L. Armstrong, Thomas M. Dreier, Andrew B. Ward, Robert A. Davey, M. Louise M. Pitt, Leah Lipsich, Peter Mason, William C. Olson, Neil Stahl, Christos A. Kyratsous

    Published 2018
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