Resultats de la cerca - M. Almond

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  1. 1
    Obesity and susceptibility to severe outcomes following respiratory viral infection

    Obesity and susceptibility to severe outcomes following respiratory viral infection per M. Almond, Michael R. Edwards, William Barclay, Sebastian L. Johnston

    Publicat 2013
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  2. 2
    Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6

    Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6 per Alice Ke, Zoe Barter, K Rowland‐Yeo, Lisa M. Almond

    Publicat 2016
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  3. 3
    Physiologically‐Based Pharmacokinetic‐Led Guidance for Patients With Cystic Fibrosis Taking Elexacaftor‐Tezacaftor‐Ivacaftor With Nirmatrelvir‐Ritonavir for the Treatment of COVID‐19

    Physiologically‐Based Pharmacokinetic‐Led Guidance for Patients With Cystic Fibrosis Taking Elexacaftor‐Tezacaftor‐Ivacaftor With Nirmatrelvir‐Ritonavir for the Treatment of COVID‐... per Eunjin Hong, Lisa M. Almond, Peter S. Chung, Adupa P. Rao, Paul M. Beringer

    Publicat 2022
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  4. 4
    The Effects of Protease Inhibitors and Nonnucleoside Reverse Transcriptase Inhibitors on P-Glycoprotein Expression in Peripheral Blood Mononuclear Cells In Vitro

    The Effects of Protease Inhibitors and Nonnucleoside Reverse Transcriptase Inhibitors on P-Glycoprotein Expression in Peripheral Blood Mononuclear Cells In Vitro per Becky Chandler, Lisa M. Almond, Jennifer Lynn Ford, Andrew Owen, Patrick G. Hoggard, Saye Khoo, David Back

    Publicat 2003
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  5. 5
    Impact of Disease on Plasma and Lung Exposure of Chloroquine, Hydroxychloroquine and Azithromycin: Application of PBPK Modeling

    Impact of Disease on Plasma and Lung Exposure of Chloroquine, Hydroxychloroquine and Azithromycin: Application of PBPK Modeling per Karen Rowland Yeo, Mian Zhang, Xian Pan, Alice Ke, Hannah M. Jones, David Wesche, Lisa M. Almond

    Publicat 2020
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  6. 6
    Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an In Vitro–In Vivo Extrapolation Model

    Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an In Vitro–In Vivo Extrapolation Model per Marco Siccardi, Lisa M. Almond, Alessandro Schipani, Chantal Csajka, Catia Marzolini, Christoph Wyen, Norbert H. Brockmeyer, Marta Boffito, Andrew Owen, David Back

    Publicat 2012
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  7. 7
    Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing

    Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing per Barbara A. Wetmore, Brittany Allen, Harvey J. Clewell, Timothy A. Parker, John F. Wambaugh, Lisa M. Almond, Mark A. Sochaski, Russell S. Thomas

    Publicat 2014
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  8. 8
    Development of a Multicompartment Permeability‐Limited Lung PBPK Model and Its Application in Predicting Pulmonary Pharmacokinetics of Antituberculosis Drugs

    Development of a Multicompartment Permeability‐Limited Lung PBPK Model and Its Application in Predicting Pulmonary Pharmacokinetics of Antituberculosis Drugs per Lu Gaohua, J. R. Wedagedera, Ben G. Small, Lisa M. Almond, Klaus Romero, Dirk M. Hermann, Debra Hanna, Masoud Jamei, I. Gardner

    Publicat 2015
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  9. 9
    Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions

    Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions per Howard Burt, Sibylle Neuhoff, Lisa M. Almond, Lu Gaohua, Matthew D. Harwood, Masoud Jamei, Amin Rostami‐Hodjegan, Geoffrey T. Tucker, K Rowland‐Yeo

    Publicat 2016
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  10. 10
    Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model

    Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model per Lisa M. Almond, Sophie Mukadam, I. Gardner, K. Okialda, Susan Wong, Oliver Hatley, Sun Tee Tay, K Rowland‐Yeo, Masoud Jamei, Amin Rostami‐Hodjegan, Jane R. Kenny

    Publicat 2016
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  11. 11
    Safety of elexacaftor/tezacaftor/ivacaftor dose reduction: Mechanistic exploration through physiologically based pharmacokinetic modeling and a clinical case series

    Safety of elexacaftor/tezacaftor/ivacaftor dose reduction: Mechanistic exploration through physiologically based pharmacokinetic modeling and a clinical case series per Eunjin Hong, Regina Li, Alan Shi, Lisa M. Almond, Joshua Wang, Amin Z. Khudari, Soumar Haddad, Sarkis Sislyan, Marissa Angelich, Peter S. Chung, Adupa P. Rao, Paul M. Beringer

    Publicat 2023
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  12. 12
    Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium

    Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium per James D. Porter, Jennifer Watson, Lee R. Roberts, Simren K. Gill, Helen Groves, Jaideep Dhariwal, M. Almond, Ernie Wong, Ross P. Walton, Lyn H. Jones, John S. Tregoning, Iain Kilty, Sebastian L. Johnston, Michael R. Edwards

    Publicat 2016
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  13. 13
    Erratum: RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

    Erratum: RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection per Agnieszka Jóźwik, Maximillian S. Habibi, Allan Paras, Jie Zhu, Aleks Guvenel, Jaideep Dhariwal, M. Almond, Ernie Wong, Annemarie Sykes, Matthew Maybeno, Jerico Del Rosario, Maria-Belen Trujillo-Torralbo, Patrick Mallia, John Sidney, Bjoern Peters, Onn Min Kon, Alessandro Sette, Sebastian L. Johnston, Peter Openshaw, Christopher Chiu

    Publicat 2016
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  14. 14
    RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

    RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection per Agnieszka Jóźwik, Maximillian S. Habibi, Allan Paras, Jie Zhu, Aleks Guvenel, Jaideep Dhariwal, M. Almond, Ernie Wong, Annemarie Sykes, Matthew Maybeno, Jerico Del Rosario, Maria‐Belen Trujillo‐Torralbo, Patrick Mallia, John Sidney, Bjoern Peters, Onn Min Kon, Alessandro Sette, Sebastian L. Johnston, Peter Openshaw, Christopher Chiu

    Publicat 2015
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  15. 15
    Obesity dysregulates the pulmonary antiviral immune response

    Obesity dysregulates the pulmonary antiviral immune response per M. Almond, Hugo Farne, Millie M. Jackson, Akhilesh Jha, Orestis Katsoulis, Oliver Pitts, Tanushree Tunstall, Eteri Regis, Jake Dunning, Adam J. Byrne, Patrick Mallia, Onn Min Kon, Ken Saunders, Karen D. Simpson, Robert J. Snelgrove, Peter Openshaw, Michael R. Edwards, William Barclay, Liam M. Heaney, Sebastian L. Johnston, Aran Singanayagam

    Publicat 2023
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  16. 16
    Addressing unmet needs in understanding asthma mechanisms

    Addressing unmet needs in understanding asthma mechanisms per Michael R. Edwards, Sejal Saglani, Jürgen Schwarze, Chrysanthi Skevaki, John A. Smith, Ben Ainsworth, M. Almond, Evangelos Andreakos, Maria G. Belvisi, Kian Fan Chung, William Cookson, Paul Cullinan, Catherine M. Hawrylowicz, Marek Lommatzsch, David J. Jackson, René Lutter, Benjamin J. Marsland, Miriam F. Moffatt, Mike Thomas, J. Christian Virchow, Georgina Xanthou, Jessica Edwards, Samantha Walker, Sebastian L. Johnston

    Publicat 2017
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  17. 17
    An in vitro toolbox to accelerate anti-malarial drug discovery and development

    An in vitro toolbox to accelerate anti-malarial drug discovery and development per Susan A. Charman, Alice Andreu, Helena Barker, Scott Blundell, Anna Campbell, Michael G. Campbell, Gong� Chen, Francis C. K. Chiu, Elly Crighton, Kasiram Katneni, Julia Morizzi, Rahul Patil, Thao Pham, Eileen Ryan, Jessica Saunders, David M. Shackleford, Karen L. White, Lisa M. Almond, Maurice Dickins, Dennis A. Smith, Joerg J. Moehrle, Jeremy N. Burrows, Nada Abla

    Publicat 2020
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  18. 18
    Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection

    Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection per Aleks Guvenel, Agnieszka Jóźwik, Stephanie Ascough, Seng Kuong Anakin Ung, Suzanna Paterson, Mohini Kalyan, Zoe Gardener, Emma Bergstrom, Satwik Kar, Maximillian S. Habibi, Allan Paras, Jie Zhu, Mirae Park, Jaideep Dhariwal, M. Almond, Ernie Wong, Annemarie Sykes, Jerico Del Rosario, Maria‐Belen Trujillo‐Torralbo, Patrick Mallia, John Sidney, Bjoern Peters, Onn Min Kon, Alessandro Sette, Sebastian L. Johnston, Peter Openshaw, Christopher Chiu

    Publicat 2019
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