Torthaí cuardaigh - Métifiot, Mathieu

HIV Integrase Inhibitors: 20-Year Landmark and Challenges de réir Métifiot, Mathieu, Marchand, Christophe, Pommier, Yves

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

HIV-1 IN Inhibitors: 2010 Update and Perspectives de réir Marchand, Christophe, Maddali, Kasthuraiah, Metifiot, Mathieu, Pommier, Yves

Faigh an téacs iomlán Faigh an téacs iomlán

Resistance to Integrase Inhibitors de réir Métifiot, Mathieu, Marchand, Christophe, Maddali, Kasthuraiah, Pommier, Yves

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

G-quadruplexes in viruses: function and potential therapeutic applications de réir Métifiot, Mathieu, Amrane, Samir, Litvak, Simon, Andreola, Marie-Line

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Molecular Dynamics Approaches Estimate the Binding Energy of HIV-1 Integrase Inhibitors and Correlate with In Vitro Activity de réir Johnson, Barry C., Métifiot, Mathieu, Pommier, Yves, Hughes, Stephen H.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

De novo RNA synthesis catalyzed by the Zika Virus RNA polymerase domain de réir Calmels, Christina, Ventura, Michel, Aknin, Cindy, Métifiot, Mathieu, Andreola, Marie-Line

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Biochemical and Pharmacological Analyses of HIV-1 Integrase Flexible Loop Mutants Resistant To Raltegravir de réir Métifiot, Mathieu, Maddali, Kasthuraiah, Naumova, Alena, Zhang, Xuemin, Marchand, Christophe, Pommier, Yves

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

A Homology Model of HIV-1 Integrase and Analysis of Mutations Designed to Test the Model de réir Johnson, Barry C., Métifiot, Mathieu, Ferris, Andrea, Pommier, Yves, Hughes, Stephen H.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Targeting the Integrated Stress Response Kinase GCN2 to Modulate Retroviral Integration de réir Torres, Chloé, Garling, Asja, Taouji, Saïd, Calmels, Christina, Andreola, Marie-Line, Métifiot, Mathieu

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Discovery of Novel Integrase Inhibitors Acting outside the Active Site Through High-Throughput Screening de réir Aknin, Cindy, Smith, Elena A., Marchand, Christophe, Andreola, Marie-Line, Pommier, Yves, Metifiot, Mathieu

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Elvitegravir overcomes resistance to raltegravir induced by integrase mutation Y143 de réir Métifiot, Mathieu, Vandegraaff, Nick, Maddali, Kasthuraiah, Naumova, Alena, Zhang, Xuemin, Rhodes, David, Marchand, Christophe, Pommier, Yves

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572) de réir Hare, Stephen, Smith, Steven J., Métifiot, Mathieu, Jaxa-Chamiec, Albert, Pommier, Yves, Hughes, Stephen H., Cherepanov, Peter

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

MK-0536 Inhibits HIV-1 Integrases Resistant to Raltegravir de réir Métifiot, Mathieu, Johnson, Barry, Smith, Steven, Zhao, Xue Zhi, Marchand, Christophe, Burke, Terrence, Hughes, Stephen, Pommier, Yves

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

6,7-Dihydroxyisoindolin-1-one and 7,8-Dihydroxy-3,4-Dihydroisoquinolin-1(2H)-one Based HIV-1 Integrase Inhibitors de réir Zhao, Xue Zhi, Métifiot, Mathieu, Smith, Steven J., Maddali, Kasthuraiah, Marchand, Christophe, Hughes, Stephen H., Pommier, Yves, Burke, Terrence R.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Bicyclic 1-Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide-Containing HIV-1 Integrase Inhibitors Having High Antiviral Potency against Cells Harboring Raltegravir-Resistant Integra... de réir Zhao, Xue Zhi, Smith, Steven J., Métifiot, Mathieu, Johnson, Barry C., Marchand, Christophe, Pommier, Yves, Hughes, Stephen H., Burke, Terrence R.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

4-Amino-1-hydroxy-2-oxo-1,8-naphthyridine-Containing Compounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV-1 de réir Zhao, Xue Zhi, Smith, Steven J., Métifiot, Mathieu, Marchand, Christophe, Boyer, Paul L., Pommier, Yves, Hughes, Stephen H., Burke, Terrence R.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

HIV-1 Integrase-Targeted Short Peptides Derived from a Viral Protein R Sequence de réir Zhao, Xue Zhi, Métifiot, Mathieu, Kiselev, Evgeny, Kessl, Jacques J., Maddali, Kasthuraiah, Marchand, Christophe, Kvaratskhelia, Mamuka, Pommier, Yves, Burke, Terrence R.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Selectivity for strand-transfer over 3′-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme–DNA interactions in the active s... de réir Métifiot, Mathieu, Johnson, Barry C., Kiselev, Evgeny, Marler, Laura, Zhao, Xue Zhi, Burke, Terrence R., Marchand, Christophe, Hughes, Stephen H., Pommier, Yves

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Absence of Resistance Mutations in the Integrase Coding Region among ART-Experienced Patients in the Republic of the Congo de réir Got, Ferdinand Emaniel Brel, Recordon-Pinson, Patricia, Loubano-Voumbi, Ghislain, Ebourombi, Dagene, Blondot, Marie-Lise, Metifiot, Mathieu, Ondzotto, Gontran, Andreola, Marie-Line

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Development of Tricyclic Hydroxy-1H-pyrrolopyridine-trione Containing HIV-1 Integrase Inhibitors de réir Zhao, Xue Zhi, Maddali, Kasthuraiah, Metifiot, Mathieu, Smith, Steven J., Vu, B. Christie, Marchand, Christophe, Hughes, Stephen H., Pommier, Yves, Burke, Terrence R.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán