Resultados da busca - Lynne Howells
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Resveratrol for the Management of Human Health: How Far Have We Come? A Systematic Review of Resveratrol Clinical Trials to Highlight Gaps and Opportunities por Karen Brown, Despoina Theofanous, Robert G. Britton, Grandezza Aburido, Coral Pepper, Shanthi Sri Undru, Lynne Howells
Publicado em 2024Revisão -
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Combining curcumin (C3-complex, Sabinsa) with standard care FOLFOX chemotherapy in patients with inoperable colorectal cancer (CUFOX): study protocol for a randomised control trial por Glen R.B. Irving, Chinenye Iwuji, Bruno Morgan, David P. Berry, William P. Steward, Anne Thomas, Karen Brown, Lynne Howells
Publicado em 2015Artigo -
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Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals por Lynne Howells, Elena P. Moiseeva, Christopher P. Neal, Bethany E. Foreman, Catherine Andreadi, Yiyang Sun, E A Hudson, Margaret M. Manson
Publicado em 2007Revisão -
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Association of Type 2 Diabetes With Cancer: A Meta-analysis With Bias Analysis for Unmeasured Confounding in 151 Cohorts Comprising 32 Million People por Suping Ling, Karen Brown, Joanne Miksza, Lynne Howells, Amy Morrison, Eyad Issa, Thomas Yates, Kamlesh Khunti, Melanie J. Davies, Francesco Zaccardi
Publicado em 2020Revisão -
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Risk of cancer incidence and mortality associated with diabetes: A systematic review with trend analysis of 203 cohorts por Suping Ling, Karen Brown, Joanne Miksza, Lynne Howells, Amy Morrison, Eyad Issa, Thomas Yates, Kamlesh Khunti, Melanie J. Davies, Francesco Zaccardi
Publicado em 2020Revisão -
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Phase I Randomized, Double-Blind Pilot Study of Micronized Resveratrol (SRT501) in Patients with Hepatic Metastases—Safety, Pharmacokinetics, and Pharmacodynamics por Lynne Howells, D.P. Berry, P.J. Elliott, Eric Jacobson, Ethan Hoffmann, Barbara C. Hegarty, Karen Brown, W P Steward, Andreas J. Gescher
Publicado em 2011Artigo -
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Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery por Ian R. Powley, Meeta Patel, Gareth J. Miles, Howard Pringle, Lynne Howells, Anne Thomas, Catherine Kettleborough, Justin S. Bryans, Tim Hammonds, Marion MacFarlane, Catrin Pritchard
Publicado em 2020Revisão -
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Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway por Vicenç Ruiz de Porras, Sara Bystrup, Anna Martínez‐Cardús, Raquel Pluvinet, Lauro Sumoy, Lynne Howells, Mark I. James, Chinenye Iwuji, José Luís Manzano, Laura Layos, Cristina Bugés, Albert Abad, Eva Martinez‐Balibrea
Publicado em 2016Artigo -
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Curcumin Combined with FOLFOX Chemotherapy Is Safe and Tolerable in Patients with Metastatic Colorectal Cancer in a Randomized Phase IIa Trial por Lynne Howells, Chinenye Iwuji, Glen R.B. Irving, Shaun Barber, Harriet S. Walter, Zahirah Sidat, Nicola Griffin-Teall, Raj Singh, Nalini Foreman, Samita R. Patel, Bruno Morgan, William P. Steward, Andreas J. Gescher, Anne Thomas, Karen Brown
Publicado em 2019Artigo -
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Curcumin ameliorates oxaliplatin‐induced chemoresistance in HCT116 colorectal cancer cells <i>in vitro</i> and <i>in vivo</i> por Lynne Howells, Stewart Sale, Sathya Neelature Sriramareddy, Glen R.B. Irving, Donald J. L. Jones, Christopher J. Ottley, D. Graham Pearson, Christopher D. Mann, Margaret M. Manson, David P. Berry, Andreas J. Gescher, William P. Steward, Karen Brown
Publicado em 2010Artigo -
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Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes por Constantia Alexandrou, Saif Sattar Al-Aqbi, Jennifer A. Higgins, William Boyle, Ankur Karmokar, Catherine Andreadi, Jinli Luo, David A. Moore, Maria Viskaduraki, Matthew Blades, Graeme I. Murray, Lynne Howells, Anne Thomas, Karen Brown, Paul N. Cheng, Alessandro Rufini
Publicado em 2018Artigo -
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Prolonged Biologically Active Colonic Tissue Levels of Curcumin Achieved After Oral Administration—A Clinical Pilot Study Including Assessment of Patient Acceptability por Glen R.B. Irving, Lynne Howells, Stewart Sale, Ines Kralj‐Hans, Wendy Atkin, Susan K. Clark, Robert G. Britton, Donald J. L. Jones, Edwina N. Scott, David P. Berry, David Hemingway, A. S. Miller, Karen Brown, Andreas J. Gescher, William P. Steward
Publicado em 2012Artigo -
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Circulating tumor DNA in patients with colorectal adenomas: assessment of detectability and genetic heterogeneity por Ni Ni Moe Myint, Ajay Verma, Daniel Fernández-García, Panchali Sarmah, Patrick Tarpey, Saif Sattar Al-Aqbi, Hong Cai, Ricky M. Trigg, Kevin West, Lynne Howells, Anne Thomas, Karen Brown, David S. Guttery, Baljit Singh, Howard Pringle, Ultan McDermott, Jacqui Shaw, Alessandro Rufini
Publicado em 2018Artigo -
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Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy por Mark I. James, Chinenye Iwuji, Glen R.B. Irving, Ankur Karmokar, Jennifer A. Higgins, Nicola Griffin-Teal, Anne Thomas, Peter Greaves, Hong Cai, Samita R. Patel, Bruno Morgan, Ashley R. Dennison, Matthew S. Metcalfe, Giuseppe Garcea, David Lloyd, David P. Berry, William P. Steward, Lynne Howells, Karen Brown
Publicado em 2015Artigo -
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Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice por Hong Cai, Edwina N. Scott, Abeer Othman A. Kholghi, Catherine Andreadi, Alessandro Rufini, Ankur Karmokar, Robert G. Britton, Emma Horner‐Glister, Peter Greaves, Dhafer Jawad, Mark I. James, Lynne Howells, Ted Ognibene, Michael Malfatti, Christopher E. Goldring, Neil R. Kitteringham, Joanne Walsh, Maria Viskaduraki, Kevin West, A. S. Miller, David Hemingway, William P. Steward, Andreas J. Gescher, Karen Brown
Publicado em 2015Artigo
Ferramentas de busca:
Assuntos relacionados
Medicine
Internal medicine
Cancer
Colorectal cancer
Pharmacology
Biology
Biochemistry
Cancer research
Curcumin
Oncology
Oxaliplatin
Biotechnology
Gene
In vivo
Resveratrol
Apoptosis
Confidence interval
Disease
Endocrinology
FOLFOX
Genetics
Randomized controlled trial
Surgery
Adverse effect
Bioinformatics
Biomarker
Chemistry
Chemotherapy
Clinical trial
Computational biology