Hakutulokset - Lynn Quek

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  1. 1
    A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen

    A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen Tekijä Lynn Quek, Joseph B. Bolen, Steve P. Watson

    Julkaistu 1998
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  2. 2
    Phosphatidylinositol 3,4,5-trisphosphate regulates Ca2+ entry via Btk in platelets and megakaryocytes without increasing phospholipase C activity

    Phosphatidylinositol 3,4,5-trisphosphate regulates Ca2+ entry via Btk in platelets and megakaryocytes without increasing phospholipase C activity Tekijä Jean‐Max Pasquet, Lynn Quek, Christiaan Stevens, Régis Bobe, Michael Huber, Vincent Duronio, Gerald Krystal, Steve P. Watson

    Julkaistu 2000
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  3. 3
    De-escalation of corticosteroids and clonal remission in UBA1 mutation-driven VEXAS syndrome with 5-azacytidine

    De-escalation of corticosteroids and clonal remission in UBA1 mutation-driven VEXAS syndrome with 5-azacytidine Tekijä Roochi Trikha, Kar Lok Kong, James Galloway, Tanya Basu, Lynn Quek, Jamie Wilson, L. Gamble, Henna Wong, Steven Best, Austin Kulasekararaj

    Julkaistu 2024
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  4. 4
    Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment

    Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment Tekijä Francis Mussai, Carmela De Santo, Issa Abu‐Dayyeh, Sarah Booth, Lynn Quek, Rosanna M. McEwen-Smith, Amrana Qureshi, Francesco Dazzi, Paresh Vyas, Vincenzo Cerundolo

    Julkaistu 2013
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  5. 5
    LAT Is Required for Tyrosine Phosphorylation of Phospholipase Cγ2 and Platelet Activation by the Collagen Receptor GPVI

    LAT Is Required for Tyrosine Phosphorylation of Phospholipase Cγ2 and Platelet Activation by the Collagen Receptor GPVI Tekijä Jean‐Max Pasquet, Barbara Gross, Lynn Quek, Naoki Asazuma, Weiguo Zhang, Connie L. Sommers, Edina Schweighoffer, Victor L. J. Tybulewicz, Barbara Judd, Jong Ran Lee, Gary A. Koretzky, Paul E. Love, Lawrence E. Samelson, Steve P. Watson

    Julkaistu 1999
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  6. 6
    Tumor Associated Macrophages Promoted Fatal Patient Derived Acute Promyelocytic Leukemia <i>In Vivo</i>

    Tumor Associated Macrophages Promoted Fatal Patient Derived Acute Promyelocytic Leukemia <i>In Vivo</i> Tekijä Isabel Weinhäuser, Diego A. Pereira‐Martins, Jacobien R. Hilberink, Luciana Yamamoto Almeida, Douglas RA Silveira, Lynn Quek, Shanna M. Hogeling, José Maurício Mota, Emanuele Ammatuna, Antonio R. Lucena‐Araujo, Gerwin Huls, Jan Jacob Schuringa, Eduardo Magalhães Rego

    Julkaistu 2021
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  7. 7
    S252: M2-POLARIZED MACROPHAGES CONTROL LEUKEMIC STEM CELL FATE BY PROMOTING METABOLIC REPROGRAMMING

    S252: M2-POLARIZED MACROPHAGES CONTROL LEUKEMIC STEM CELL FATE BY PROMOTING METABOLIC REPROGRAMMING Tekijä I. Weinhäuser, Diego A. Pereira‐Martins, Jacobien R. Hilberink, L. Y. Almeida, Douglas RA Silveira, Lynn Quek, Shanna M. Hogeling, José Maurício Mota, Emanuele Ammatuna, Antonio R. Lucena‐Araujo, Gerwin Huls, Eduardo Magalhães Rego, Jan Jacob Schuringa

    Julkaistu 2022
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  8. 8
    M2 Macrophages Drive Resistance to Phagocytosis and Improve Mitochondrial Metabolism in Acute Myeloid Leukemia Facilitating Leukemic Transformation and <i>In Vivo</i> Engraftment

    M2 Macrophages Drive Resistance to Phagocytosis and Improve Mitochondrial Metabolism in Acute Myeloid Leukemia Facilitating Leukemic Transformation and <i>In Vivo</i> Engraftment Tekijä Isabel Weinhaeuser, Diego A. Pereira‐Martins, Luciana Yamamoto Almeida, Jacobien R. Hilberink, Douglas RA Silveira, Lynn Quek, César Alexander Ortiz Rojas, Antonio R. Lucena‐Araujo, Nienke Visser, Emanuele Ammatuna, Gerwin Huls, Eduardo Magalhães Rego, Jan Jacob Schuringa

    Julkaistu 2022
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  9. 9
    P466: THE INTRINSICALLY DISORDERED TRANSCRIPTIONAL REGULATOR MN1 DEPENDS ON THE CHAPERONE DNAJB6B FOR ITS FULL TRANSFORMING POTENTIAL

    P466: THE INTRINSICALLY DISORDERED TRANSCRIPTIONAL REGULATOR MN1 DEPENDS ON THE CHAPERONE DNAJB6B FOR ITS FULL TRANSFORMING POTENTIAL Tekijä Diego A. Pereira‐Martins, Vincent van den Boom, Noortje van Dijk, Isabel Weinhäuser, Douglas RA Silveira, Thiago Mantello Bianco, César Alexander Ortiz Rojas, Gerwin Huls, Lynn Quek, Antonio R. Lucena‐Araujo, Eduardo Magalhães Rego, Jan Jacob Schuringa

    Julkaistu 2023
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  10. 10
    Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia

    Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia Tekijä Lynn Quek, Paul Ferguson, Marlen Metzner, Ikhlaaq Ahmed, Alison Kennedy, Catherine Garnett, Sally Jeffries, Claudia Walter, Kim Piechocki, Adele Timbs, Robert Danby, Manoj Raghavan, Andrew Peniket, Mike Griffiths, Andrew Bacon, Janice Ward, Keith Wheatley, Paresh Vyas, Charles Craddock

    Julkaistu 2016
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  11. 11
    Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells

    Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells Tekijä Dimitris Karamitros, Bilyana Stoilova, Zahra Aboukhalil, Fiona Hamey, Andreas Reinisch, Marina Samitsch, Lynn Quek, Georg Otto, Emmanouela Repapi, Jessica Doondeea, Batchimeg Usukhbayar, Julien Calvo, Stephen Taylor, Nicolas Goardon, Emmanuelle Six, Françoise Pflumio, Catherine Porcher, Ravindra Majeti, Berthold Göttgens, Paresh Vyas

    Julkaistu 2017
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  12. 12
    S127: DELTATP73 IMPOSES TP53 MUTANT-LIKE PHENOTYPES INCLUDING DRUG RESISTANCE AND POOR PROGNOSIS ON TP53-WILD TYPE ACUTE MYELOID LEUKEMIA.

    S127: DELTATP73 IMPOSES TP53 MUTANT-LIKE PHENOTYPES INCLUDING DRUG RESISTANCE AND POOR PROGNOSIS ON TP53-WILD TYPE ACUTE MYELOID LEUKEMIA. Tekijä Diego A. Pereira‐Martins, César Alexander Ortiz Rojas, Isabel Weinhäuser, Douglas RA Silveira, Albertus T.J. Wierenga, Vincent van den Boom, Thiago Mantello Bianco, Emanuele Ammatuna, Lynn Quek, Antonio R. Lucena‐Araujo, Gerwin Huls, Eduardo Magalhães Rego, Jan Jacob Schuringa

    Julkaistu 2023
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  13. 13
    Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response

    Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response Tekijä Michael Amatangelo, Lynn Quek, Alan H. Shih, Eytan M. Stein, Mikhail Roshal, Muriel D. David, Benoît Marteyn, Noushin Farnoud, Stéphane de Botton, Olivier Bernard, Bin Wu, Katharine Yen, Martin S. Tallman, Elli Papaemmanuil, Virginie Penard‐Lacronique, Anjan Thakurta, Paresh Vyas, Ross L. Levine

    Julkaistu 2017
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  14. 14
    P439: ASSOCIATING EX VIVO DRUG SENSITIVITY WITH METABOLIC STATUS IDENTIFIES EFFECTIVE COMBINATION STRATEGIES IN ACUTE MYELOID LEUKEMIA

    P439: ASSOCIATING EX VIVO DRUG SENSITIVITY WITH METABOLIC STATUS IDENTIFIES EFFECTIVE COMBINATION STRATEGIES IN ACUTE MYELOID LEUKEMIA Tekijä Diego A. Pereira‐Martins, Emmanuel Griessinger, Isabel Weinhäuser, Juan Luiz Coelho‐Silva, Douglas RA Silveira, Lynn Quek, Ayşegül Erdem, Jacobien R. Hilberink, E. V. de Paula, Sara Teresinha Olalla Saad, Emanuele Ammatuna, Gerwin Huls, Eduardo Magalhães Rego, Antonio R. Lucena‐Araujo, Jan Jacob Schuringa

    Julkaistu 2022
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  15. 15
    Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature

    Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature Tekijä Charles Craddock, Aimee E. Houlton, Lynn Quek, Paul Ferguson, Emma Gbandi, Corran Roberts, Marlen Metzner, Natalia Garcia-Martin, Alison Kennedy, Angela Hamblin, Manoj Raghavan, Sandeep Nagra, Louise Dudley, Keith Wheatley, Mary Frances McMullin, Srinivas Pillai, Richard Kelly, Shamyla Siddique, Michael Dennis, Jamie Cavenagh, Paresh Vyas

    Julkaistu 2017
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  16. 16
    Enasidenib Plus Azacitidine Significantly Improves Complete Remission and Overall Response Compared with Azacitidine Alone in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) with Isocitrate Dehydrogenase 2 (IDH2) Mutations: Interim Phase II Results from an Ongoing, Randomized Study

    Enasidenib Plus Azacitidine Significantly Improves Complete Remission and Overall Response Compared with Azacitidine Alone in Patients with Newly Diagnosed Acute Myeloid Leukemia (... Tekijä Courtney D. DiNardo, Andre C. Schuh, Eytan M. Stein, Pau Montesinos Fernández, Andrew H. Wei, Stéphane de Botton, Amer M. Zeidan, Amir T. Fathi, Lynn Quek, Hagop M. Kantarjian, Mark G. Frattini, Frederik Lersch, Jing Gong, Aleksandra Franovic, Kyle J. MacBeth, Paresh Vyas, Hartmut Döhner

    Julkaistu 2019
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  17. 17
    CEBPA-Driven Expression of the Transcriptionally Inactive deltaTP73 Isoform Phenocopies <i>TP53</i>mutated Poor Risk and Drug-Resistant Acute Myeloid Leukemia

    CEBPA-Driven Expression of the Transcriptionally Inactive deltaTP73 Isoform Phenocopies <i>TP53</i>mutated Poor Risk and Drug-Resistant Acute Myeloid Leukemia Tekijä Diego A. Pereira‐Martins, César Alexander Ortiz Rojas, Isabel Weinhaeuser, Bart‐Jan Wierenga, Vincent van den Boom, Fatemeh Mojallali, Dominique Sternadt, Thiago Mantello Bianco, Nisha van der Meer, Douglas RA Silveira, Lynn Quek, Emanuele Ammatuna, Antonio R. Lucena‐Araujo, Gerwin Huls, Eduardo Magalhães Rego, Jan Jacob Schuringa

    Julkaistu 2023
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  18. 18
    Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia

    Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia Tekijä Douglas RA Silveira, Lynn Quek, Itamar S Santos, Anna Corby, Juan Luiz Coelho‐Silva, Diego A. Pereira‐Martins, Grant Vallance, Benjamin Brown, Luciana Nardinelli, Wellington F Silva, Elvira Deolinda Rodrigues Pereira Velloso, Antonio R. Lucena‐Araujo, Fabı́ola Traina, Andy Peniket, Paresh Vyas, Eduardo Magalhães Rego, Israel Bendit, Vanderson Rocha

    Julkaistu 2020
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  19. 19
    A multicenter comparative acute myeloid leukemia study: can we explain the differences in the outcomes in resource-constrained settings?

    A multicenter comparative acute myeloid leukemia study: can we explain the differences in the outcomes in resource-constrained settings? Tekijä Douglas RA Silveira, Juan Luiz Coelho‐Silva, Wellington F Silva, Grant Vallance, Diego A. Pereira‐Martins, Maria Isabel Ayrosa Madeira, Lorena Lobo Figueiredo‐Pontes, Elvira Deolinda Rodrigues Pereira Velloso, Belinda Pinto Simões, Andy Peniket, Robert Danby, Eduardo Magalhães Rego, Paresh Vyas, Fabı́ola Traina, Israel Bendit, Lynn Quek, Vanderson Rocha

    Julkaistu 2020
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  20. 20
    Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia

    Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia Tekijä Sachith Mettananda, Chris Fisher, Deborah Hay, Mohsin Badat, Lynn Quek, Kevin Clark, Philip Hublitz, Damien J. Downes, Jon Kerry, Matthew Gosden, Jelena Telenius, Jackie Sloane‐Stanley, Paula Faustino, Andreia Coelho, Jessica Doondeea, Batchimeg Usukhbayar, Paul Sopp, Jacqueline A. Sharpe, Jim R. Hughes, Paresh Vyas, Richard J. Gibbons, Douglas R. Higgs

    Julkaistu 2017
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