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  1. 1
    Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma

    Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma por Sally L. George, Virinder S. Parmar, Federica Lorenzi, Lynley V. Marshall, Yann Jamin, Evon Poon, Paola Angelini, Louis Chesler

    Publicado em 2020
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  2. 2
    MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase–Mediated <i>HOX</i>/Stem Cell Gene Signature

    MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase–Mediated <i>HOX</i>/Stem Cell Gene Signature por Nathalie Gaspar, Lynley V. Marshall, Lara Perryman, Dorine A. Bax, Suzanne E. Little, Marta Viana‐Pereira, Swee Y. Sharp, Gilles Vassal, Andrew D.J. Pearson, Rui Manuel Reis, Darren Hargrave, Paul Workman, Chris Jones

    Publicado em 2010
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  3. 3
    Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study

    Regorafenib plus Vincristine and Irinotecan in Pediatric Patients with Recurrent/Refractory Solid Tumors: An Innovative Therapy for Children with Cancer Study por Michela Casanova, Francisco Bautista, Quentin Campbell-Hewson, Guy Makin, Lynley V. Marshall, Arnauld Verschuur, Adela Cañete, Nadège Corradini, Bart A. Ploeger, Barbara J. Brennan, Udo Mueller, Hong Zebger‐Gong, John W. Chung, Birgit Geoerger

    Publicado em 2023
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  4. 4
    Repeatability of derived parameters from histograms following non-Gaussian diffusion modelling of diffusion-weighted imaging in a paediatric oncological cohort

    Repeatability of derived parameters from histograms following non-Gaussian diffusion modelling of diffusion-weighted imaging in a paediatric oncological cohort por Neil P. Jerome, Keiko Miyazaki, David J. Collins, Matthew Orton, James A. d’Arcy, Toni Wallace, Lucas Moreno, Andrew D.J. Pearson, Lynley V. Marshall, Fernando Carceller, Martin O. Leach, Stergios Zacharoulis, Dow‐Mu Koh

    Publicado em 2016
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  5. 5
    Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development

    Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development por Dorine A. Bax, Suzanne E. Little, Nathalie Gaspar, Lara Perryman, Lynley V. Marshall, Marta Viana‐Pereira, T. Alwyn Jones, Richard D. Williams, Anita Grigoriadis, Gilles Vassal, Paul Workman, Denise Sheer, Rui Manuel Reis, Andrew D.J. Pearson, Darren Hargrave, Chris Jones

    Publicado em 2009
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  6. 6
    An exceptionally rare case of a diffuse midline glioma with concomitant H3.1 K27M and G34R mutations in the HIST1H3C (H3C3) gene

    An exceptionally rare case of a diffuse midline glioma with concomitant H3.1 K27M and G34R mutations in the HIST1H3C (H3C3) gene por Zita Reisz, Rita Pereira, Smitha Nevis, Alan Mackay, Leena Bhaw, Yura Grabovska, Ross C. Laxton, Valeria Molinari, Anna Burford, Barnaby Clark, Cristina Bleil, Bassel Zebian, Erika Pace, Annette Weiser, Fernando Carceller, Lynley V. Marshall, Andrew King, István Bódi, Safa Al‐Sarraj, Chris Jones, Matthew Clarke

    Publicado em 2025
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  7. 7
    A Phase I Trial of AT9283 (a Selective Inhibitor of Aurora Kinases) in Children and Adolescents with Solid Tumors: A Cancer Research UK Study

    A Phase I Trial of AT9283 (a Selective Inhibitor of Aurora Kinases) in Children and Adolescents with Solid Tumors: A Cancer Research UK Study por Lucas Moreno, Lynley V. Marshall, Andrew D.J. Pearson, Bruce Morland, Martin Elliott, Quentin Campbell‐Hewson, Guy Makin, Sarah Halford, Gary D Acton, Philip Ross, Shamim Kazmi-Stokes, Victoria Lock, Ana Isabel Enríquez Rodríguez, John F. Lyons, Alan V. Boddy, Melanie J. Griffin, Murray Yule, Darren Hargrave

    Publicado em 2014
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  8. 8
    HG-11 * INTEGRATIVE MOLECULAR META-ANALYSIS OF 700 PEDIATRIC HIGH GRADE GLIOMA AND DIPG DEFINES WIDESPREAD INTER- AND INTRA-TUMORAL HETEROGENEITY

    HG-11 * INTEGRATIVE MOLECULAR META-ANALYSIS OF 700 PEDIATRIC HIGH GRADE GLIOMA AND DIPG DEFINES WIDESPREAD INTER- AND INTRA-TUMORAL HETEROGENEITY por Alan Mackay, Maria Vinci, Anna Burford, L. Bjerke, Kathryn Taylor, Meera Nandhabalan, Lynley V. Marshall, Valeria Molinari, Sergey Popov, Wendy J. Ingram, Andrew S. Moore, Saoussen Trabelsi, D. Hmida, Ketao Mu, Lucas Tadeu Bidinotto, Rui Manuel Reis, Ho‐Keung Ng, André O. von Bueren, Michael Baudis, Chris Jones

    Publicado em 2015
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  9. 9
    Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

    Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients por Elisa Izquierdo, Paula Proszek, Giulia Pericoli, Sara Temelso, Matthew Clarke, Diana Carvalho, Alan Mackay, Lynley V. Marshall, Fernando Carceller, Darren Hargrave, Birgitta Lannering, Zdeněk Pavelka, Simon Bailey, Natacha Entz‐Werlé, Jacques Grill, Gilles Vassal, Daniel Rodriguez Gutierrez, Paul S. Morgan, Tim Jaspan, Angela Mastronuzzi, Maria Vinci, Michael Hubank, Chris Jones

    Publicado em 2021
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  10. 10
    EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines

    EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines por Dorine A. Bax, Nathalie Gaspar, Suzanne E. Little, Lynley V. Marshall, Lara Perryman, Marie Regairaz, Marta Viana‐Pereira, Raisa Vuononvirta, Swee Y. Sharp, Jorge S. Reis‐Filho, João N. Stávale, Safa Al‐Sarraj, Rui Manuel Reis, Gilles Vassal, Andrew D.J. Pearson, Darren Hargrave, David W. Ellison, Paul Workman, Chris Jones

    Publicado em 2009
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  11. 11
    Data from EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines

    Data from EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines por Dorine A. Bax, Nathalie Gaspar, Suzanne E. Little, Lynley V. Marshall, Lara Perryman, Marie Regairaz, Marta Viana‐Pereira, Raisa Vuononvirta, Swee Y. Sharp, Jorge S. Reis‐Filho, João Norberto Stávale, Safa Al‐Sarraj, Rui Manuel Reis, Gilles Vassal, Andrew D.J. Pearson, Darren Hargrave, David W. Ellison, Paul Workman, Chris Jones

    Publicado em 2023
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  12. 12
    ACCELERATE – Five years accelerating cancer drug development for children and adolescents

    ACCELERATE – Five years accelerating cancer drug development for children and adolescents por Andrew D.J. Pearson, Susan Weiner, Peter C. Adamson, Dominik Karres, Gregory H. Reaman, Raphaël F. Rousseau, P. Blanc, Koen Norga, Jeffrey Skolnik, Pamela Kearns, Nicole Scobie, Elly Barry, Lynley V. Marshall, Leona Knox, Hubert Caron, Darshan Wariabharaj, Alberto S. Pappo, Steven G. DuBois, Lia Gore, Mark W. Kieran, Brenda J. Weigel, Elizabeth Fox, Karsten Nysom, Teresa de Rojas, Gilles Vassal

    Publicado em 2022
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  13. 13
    Joint adolescent–adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform—ACCELERATE

    Joint adolescent–adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform—ACCELERATE por Nathalie Gaspar, Lynley V. Marshall, Debbie Binner, Ralf Herold, Raphaël F. Rousseau, P. Blanc, Renaud Capdeville, Jacqueline Carleer, Christopher Copland, Yannick Kerloëguen, Koen Norga, Lida Pacaud, M.-A. Sevaux, Cesare Spadoni, Jaroslav Štěrba, Franca Ligas, Tillmann Taube, Martina Uttenreuther‐Fischer, Silvia Chioato, Michael A. O’Connell, Birgit Geoerger, Jean‐Yves Blay, Jean‐Charles Soria, S.B. Kaye, Beate Wulff, Laurence Brugières, Gilles Vassal, Andrew D.J. Pearson

    Publicado em 2018
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  14. 14
    Entrectinib in children and young adults with solid or primary CNS tumors harboring <i>NTRK</i>, <i>ROS1</i>, or <i>ALK</i> aberrations (STARTRK-NG)

    Entrectinib in children and young adults with solid or primary CNS tumors harboring <i>NTRK</i>, <i>ROS1</i>, or <i>ALK</i> aberrations (STARTRK-NG) por Ami V. Desai, Giles Robinson, Karen Gauvain, Ellen M. Basu, Margaret E. Macy, Luke Maese, Nicholas Whipple, Amit J. Sabnis, Jennifer H. Foster, Suzanne Shusterman, Janet Yoon, Brian Weiss, Mohamed S Abdelbaki, Amy E. Armstrong, Thomas F. Cash, Christine A. Pratilas, Nadège Corradini, Lynley V. Marshall, Mufiza Farid‐Kapadia, Saibah Chohan, Clare Devlin, Georgina Meneses‐Lorente, Alison K. Cardenas, Katherine E. Hutchinson, Guillaume Bergthold, Hubert Caron, Edna Chow Maneval, Amar Gajjar, Elizabeth Fox

    Publicado em 2022
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  15. 15
    Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells

    Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells por Maria Vinci, Anna Burford, Valeria Molinari, Ketty Kessler, Sergey Popov, Matthew Clarke, Kathryn R. Taylor, Helen N. Pemberton, Christopher J. Lord, Alice Gutteridge, Tim Forshew, Diana Carvalho, Lynley V. Marshall, Elizabeth Y. Qin, Wendy J. Ingram, Andrew S. Moore, Ho‐Keung Ng, Saoussen Trabelsi, Dorra H’mida-Ben Brahim, Natacha Entz‐Werlé, Stergios Zacharoulis, Sucheta Vaidya, Henry Mandeville, Leslie Bridges, Andrew J. Martin, Safa Al‐Sarraj, Christopher Chandler, Mariona Suñol, Jaume Mora, Carmen de Torres, Ofelia Cruz, Ángel M. Carcaboso, Michelle Monje, Alan Mackay, Chris Jones

    Publicado em 2018
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  16. 16
    A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

    A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations por Sally L. George, Elisa Izquierdo, James Campbell, Eleni Koutroumanidou, Paula Proszek, Sabri Jamal, Deborah Hughes, Lina Yuan, Lynley V. Marshall, Fernando Carceller, Julia Chisholm, Sucheta Vaidya, Henry Mandeville, Paola Angelini, Ajla Wasti, Tomas Sjöberg Bexelius, Khin Thway, Susanne A. Gatz, Matthew Clarke, Bissan Al‐Lazikani, Giuseppe Barone, John Anderson, Deborah A. Tweddle, David González, Brian A. Walker, Jack Barton, Sarita Depani, Jessica Eze, Saira Waqar Ahmed, Lucas Moreno, Andrew D.J. Pearson, Janet Shipley, Chris Jones, Darren Hargrave, Thomas S. Jacques, Michael Hubank, Louis Chesler

    Publicado em 2019
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  17. 17
    Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results

    Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results por Kelly C. Goldsmith, Julie R. Park, Kimberly Kayser, Jemily Malvar, Yueh‐Yun Chi, Susan Groshen, Judith G. Villablanca, Kateryna Krytska, Lillian M. Lai, Patricia T. Acharya, Fariba Goodarzian, Bruce Pawel, Hiroyuki Shimada, Susan Ghazarian, Lisa J. States, Lynley V. Marshall, Louis Chesler, Meaghan Granger, Ami V. Desai, Rajen Mody, Daniel A. Morgenstern, Suzanne Shusterman, Margaret E. Macy, Navin Pinto, Gudrun Schleiermacher, Kieuhoa T. Vo, Holger Thurm, Joseph Chen, Marlon Liyanage, Gerson Peltz, Katherine K. Matthay, Esther R. Berko, John M. Maris, Araz Marachelian, Yaël P. Mossé

    Publicado em 2023
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  18. 18
    Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma

    Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and Internat... por Lucas Moreno, Giuseppe Barone, Steven G. DuBois, Jan J. Molenaar, Matthias Fischer, Johannes H. Schulte, Angelika Eggert, Gudrun Schleiermacher, Frank Speleman, Louis Chesler, Birgit Geoerger, Michael D. Hogarty, Meredith S. Irwin, Nick Bird, Guy B. Blanchard, Sean Buckland, Hubert Caron, Susan R. Davis, Bram De Wilde, Hedwig E. Deubzer, M. Emmy M. Dolman, Martin Eilers, Rani E. George, Sally L. George, Štěrba Jaroslav, John M. Maris, Lynley V. Marshall, Melinda S. Merchant, Peter G. Mortimer, Cormac Owens, Anna Philpott, Evon Poon, Jerry W. Shay, Roberto Tonelli, Dominique Valteau‐Couanet, Gilles Vassal, Julie R. Park, Andrew D.J. Pearson

    Publicado em 2020
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  19. 19
    Paediatric Strategy Forum for medicinal product development for acute myeloid leukaemia in children and adolescents

    Paediatric Strategy Forum for medicinal product development for acute myeloid leukaemia in children and adolescents por Andrew D.J. Pearson, C. Michel Zwaan, E. Anders Kolb, Dominik Karres, Julie Guillot, Su Young Kim, Lynley V. Marshall, Sarah K. Tasian, Malcolm A. Smith, Todd M. Cooper, Peter C. Adamson, Elly Barry, Bouchra Benettaib, Florence Binlich, Anne Borgman, Erica Brivio, Renaud Capdeville, David Delgado, Douglas V. Faller, Linda Fogelstrand, Paula G. Fraenkel, Henrik Hasle, Delphine Heenen, Gertjan J.L. Kaspers, Mark W. Kieran, Jan‐Henning Klusmann, Giovanni Lesa, Franca Ligas, Silvia Mappa, Hesham Mohamed, Andrew S. Moore, Joan Morris, Kerri Nottage, Dirk Reinhardt, Nicole Scobie, Stephen J. Simko, Thomas Winkler, Koen Norga, Gregory H. Reaman, Gilles Vassal

    Publicado em 2020
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  20. 20
    Second Paediatric Strategy Forum for anaplastic lymphoma kinase (ALK) inhibition in paediatric malignancies

    Second Paediatric Strategy Forum for anaplastic lymphoma kinase (ALK) inhibition in paediatric malignancies por Andrew D.J. Pearson, Elly Barry, Yaël P. Mossé, Franca Ligas, Nick Bird, Teresa de Rojas, Zachary Zimmerman, Keith D. Wilner, Willi Woessmann, Susan Weiner, Brenda J. Weigel, Rajkumar Venkatramani, D Valteau, Toby N. Trahair, Malcolm A. Smith, Sonia Singh, Giovanni Selvaggi, Nicole Scobie, Gudrun Schleiermacher, Nicholas C. Richardson, Julie Park, Karsten Nysom, Koen Norga, Margret Merino, Joe McDonough, Yousif Matloub, Lynley V. Marshall, Eric Lowe, Giovanni Lesa, Meredith S. Irwin, Dominik Karres, Amar Gajjar, François Doz, Elizabeth Fox, Steven G. DuBois, Martha Donoghue, Michela Casanova, Hubert Caron, Victoria Buenger, Diana Bradford, P. Blanc, Amy Barone, Gregory H. Reaman, Gilles Vassal

    Publicado em 2021
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