Search Results - Luke Whiley

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  1. 1
    A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS

    A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS by Nicola Gray, Nathan G. Lawler, Rongchang Yang, Aude-Claire Morillon, Melvin Gay, Sze-How Bong, Elaine Holmes, Jeremy K. Nicholson, Luke Whiley

    Published 2020
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  2. 2
    Dried Blood Spot Microsampling: A Semi-Quantitative 4D-Lipidomics Approach Using Ultra High Performance Liquid Chromatography - High Resolution Mass Spectrometry (UHPLC-HRMS)

    Dried Blood Spot Microsampling: A Semi-Quantitative 4D-Lipidomics Approach Using Ultra High Performance Liquid Chromatography - High Resolution Mass Spectrometry (UHPLC-HRMS) by Jayden Lee Roberts, Monique Ryan, Luke Whiley, Melvin Gay, Vimalnath Nambiar, Elaine Holmes, Jeremy K. Nicholson, Julien Wist, Nicola Gray, Nathan G. Lawler

    Published 2025
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  3. 3
    Comprehensive Lipidomic Workflow for Multicohort Population Phenotyping Using Stable Isotope Dilution Targeted Liquid Chromatography-Mass Spectrometry

    Comprehensive Lipidomic Workflow for Multicohort Population Phenotyping Using Stable Isotope Dilution Targeted Liquid Chromatography-Mass Spectrometry by Monique Ryan, Alanah Grant-St James, Nathan G. Lawler, Mark W. Fear, Edward Raby, Fiona Wood, Garth Maker, Julien Wist, Elaine Holmes, Jeremy K. Nicholson, Luke Whiley, Nicola Gray

    Published 2023
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  4. 4
    Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease

    Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease by Petroula Proitsi, M Kim, Luke Whiley, Megan Pritchard, Reynold Leung, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Pak C. Sham, Simon Lovestone, John Powell, Richard Dobson, Cristina Legido‐Quigley

    Published 2015
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  5. 5
    Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma—Application to Clinical and Epidemiology Cohorts

    Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Pl... by Luke Whiley, Leanne C. Nye, Isobelle Grant, Nick Andreas, Katie E. Chappell, Magali Sarafian, Ravi Misra, Robert S. Plumb, Matthew R. Lewis, Jeremy K. Nicholson, Elaine Holmes, Jonathan R. Swann, Ian D. Wilson

    Published 2019
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  6. 6
    Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease

    Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease by Luke Whiley, Arundhuti Sen, James Heaton, Petroula Proitsi, Diego García‐Gómez, Rufina Leung, Norman W. Smith, Madhav Thambisetty, Iwona Kłoszewska, Patrizia Mecocci, Hilkka Soininen, Magda Tsolaki, Bruno Vellas, Simon Lovestone, Cristina Legido‐Quigley

    Published 2013
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  7. 7
    Diagnostic Potential of the Plasma Lipidome in Infectious Disease: Application to Acute SARS-CoV-2 Infection

    Diagnostic Potential of the Plasma Lipidome in Infectious Disease: Application to Acute SARS-CoV-2 Infection by Nicola Gray, Nathan G. Lawler, Annie Xu Zeng, Monique Ryan, Sze-How Bong, Berin A. Boughton, Maider Bizkarguenaga, Chiara Bruzzone, Nieves Embade, Julien Wist, Elaine Holmes, Óscar Millet, Jeremy K. Nicholson, Luke Whiley

    Published 2021
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  8. 8
    Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis

    Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis by Petroula Proitsi, Min Kim, Luke Whiley, Andrew Simmons, Martina Sattlecker, Latha Velayudhan, Michelle K. Lupton, Hillka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone, John Powell, Richard Dobson, Cristina Legido‐Quigley

    Published 2016
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  9. 9
    Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples

    Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special... by Ruey Leng Loo, Samantha Lodge, Torben Kimhofer, Sze-How Bong, Sofina Begum, Luke Whiley, Nicola Gray, John C. Lindon, Philipp Nitschke, Nathan G. Lawler, Hartmut Schäfer, Manfred Spraul, Toby Richards, Jeremy K. Nicholson, Elaine Holmes

    Published 2020
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  10. 10
    Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease

    Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s... by Luke Whiley, Katie E. Chappell, Ellie D’Hondt, Matthew R. Lewis, Beatriz Jiménez, Stuart G. Snowden, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Jonathan R. Swann, Abdul Hye, Simon Lovestone, Cristina Legido‐Quigley, Elaine Holmes

    Published 2021
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  11. 11
    Integrative Plasma Metabolic and Lipidomic Modelling of SARS-CoV-2 Infection in Relation to Clinical Severity and Early Mortality Prediction

    Integrative Plasma Metabolic and Lipidomic Modelling of SARS-CoV-2 Infection in Relation to Clinical Severity and Early Mortality Prediction by Samantha Lodge, Nathan G. Lawler, Nicola Gray, Reika Masuda, Philipp Nitschke, Luke Whiley, Sze-How Bong, Bu B. Yeap, Girish Dwivedi, Manfred Spraul, Hartmut Schaefer, Rubén Gil‐Redondo, Nieves Embade, Óscar Millet, Elaine Holmes, Julien Wist, Jeremy K. Nicholson

    Published 2023
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  12. 12
    Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer’s Disease

    Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer’s Disease by Min Kim, Alejo Nevado‐Holgado, Luke Whiley, Stuart G. Snowden, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Madhav Thambisetty, Richard Dobson, John Powell, Michelle K. Lupton, Andy Simmons, Latha Velayudhan, Simon Lovestone, Petroula Proitsi, Cristina Legido‐Quigley

    Published 2016
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  13. 13
    XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules

    XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules by Xavier Domingo-Almenara, J. Rafael Montenegro-Burke, Julijana Ivanišević, Aurélien Thomas, Jonathan Sidibé, Tony Teav, Carlos Guijas, Aries Aisporna, Duane Rinehart, Linh Hoang, Anders Nordström, María Gómez‐Romero, Luke Whiley, Matthew R. Lewis, Jeremy K. Nicholson, H. Paul Benton, Gary Siuzdak

    Published 2018
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  14. 14
    Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection

    Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection by Torben Kimhofer, Samantha Lodge, Luke Whiley, Nicola Gray, Ruey Leng Loo, Nathan G. Lawler, Philipp Nitschke, Sze-How Bong, David Morrison, Sofina Begum, Toby Richards, Bu B. Yeap, Christopher A. Smith, Kenneth G. C. Smith, Elaine Holmes, Jeremy K. Nicholson

    Published 2020
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  15. 15
    Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor

    Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor by George Zhang Wei, Katherine A. Martin, Peter Yuli Xing, Ruchi Agrawal, Luke Whiley, Thomas K. Wood, Sophia Hejndorf, Yong Zhi Ng, Jeremy Zhi Yan Low, Janet Rossant, Robert Nechanitzky, Elaine Holmes, Jeremy K. Nicholson, Eng-King Tan, Paul M. Matthews, Sven Pettersson

    Published 2021
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  16. 16
    A patient-centric modeling framework captures recovery from SARS-CoV-2 infection

    A patient-centric modeling framework captures recovery from SARS-CoV-2 infection by Hélène Ruffieux, Aimee L. Hanson, Samantha Lodge, Nathan G. Lawler, Luke Whiley, Nicola Gray, Tui H. Nolan, Laura Bergamaschi, Federica Mescia, Lorinda Turner, Aloka De, Victoria S. Pelly, Prasanti Kotagiri, Nathalie Kingston, John R. Bradley, Elaine Holmes, Julien Wist, Jeremy K. Nicholson, Paul Lyons, Kenneth G. C. Smith, Sylvia Richardson, Glenn R. Bantug, Christoph Hess

    Published 2023
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  17. 17
    Urinary metabolic phenotyping for Alzheimer’s disease

    Urinary metabolic phenotyping for Alzheimer’s disease by Natalja Kurbatova, Manik Garg, Luke Whiley, Elena Chekmeneva, Beatriz Jiménez, María Gómez‐Romero, Jake T. M. Pearce, Torben Kimhofer, Ellie D’Hondt, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Dag Aarsland, Alejo Nevado‐Holgado, Benjamine Liu, Stuart G. Snowden, Petroula Proitsi, Nicholas J. Ashton, Abdul Hye, Cristina Legido‐Quigley, Matthew R. Lewis, Jeremy K. Nicholson, Elaine Holmes, Alvis Brāzma, Simon Lovestone

    Published 2020
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  18. 18
    Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome

    Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome by Elaine Holmes, Julien Wist, Reika Masuda, Samantha Lodge, Philipp Nitschke, Torben Kimhofer, Ruey Leng Loo, Sofina Begum, Berin A. Boughton, Rongchang Yang, Aude-Claire Morillon, Sung‐Tong Chin, Drew A. Hall, Monique Ryan, Sze-How Bong, Melvin Gay, Dale W. Edgar, John C. Lindon, Toby Richards, Bu B. Yeap, Sven Pettersson, Manfred Spraul, Hartmut Schaefer, Nathan G. Lawler, Nicola Gray, Luke Whiley, Jeremy K. Nicholson

    Published 2021
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