Search Results - Luke Jostins

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  1. 1
    Genetic risk prediction in complex disease

    Genetic risk prediction in complex disease by Luke Jostins, Jeffrey C. Barrett

    Published 2011
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  2. 2
    Microindel detection in short-read sequence data

    Microindel detection in short-read sequence data by Peter Krawitz, Christian Rödelsperger, Marten Jäger, Luke Jostins, Sebastian Bauer, Peter N. Robinson

    Published 2010
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  3. 3
    Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank

    Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank by Adrián Cortés, Calliope A. Dendrou, Allan Motyer, Luke Jostins, Damjan Vukcevic, Alexander Dilthey, Peter Donnelly, Stephen Leslie, Lars Fugger, Gil McVean

    Published 2017
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  4. 4
    Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families

    Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families by Adam P. Levine, Nikolas Pontikos, Elena Schiff, Luke Jostins, Doug Speed, Laurence Lovat, Jeffrey C. Barrett, Helmut Grasberger, Vincent Plagnol, Anthony W. Segal

    Published 2016
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  5. 5
    Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis

    Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis by Isabell S. von Loga, Aadil El-Turabi, Luke Jostins, Jadwiga Miotla‐Zarebska, Jennifer Alderson, Andris Zeltiņš, Ida Parisi, Martin F. Bachmann, Tonia L. Vincent

    Published 2019
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  6. 6
    Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression

    Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression by Benjamin P. Fairfax, Peter Humburg, Seiko Makino, Vivek Naranbhai, Daniel Wong, Evelyn Lau, Luke Jostins, Katharine Plant, Robert Andrews, Chris McGee, Julian C. Knight

    Published 2014
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  7. 7
    Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease

    Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease by James Lee, Daniele Biasci, Rebecca Roberts, Richard B. Gearry, John Mansfield, Tariq Ahmad, Natalie J. Prescott, Jack Satsangi, David C. Wilson, Luke Jostins, Carl A. Anderson, James A. Traherne, Paul Lyons, Miles Parkes, Kenneth G. C. Smith

    Published 2017
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  8. 8
    The National Genomics Research and Healthcare Knowledgebase

    The National Genomics Research and Healthcare Knowledgebase by Mark J. Caulfield, Jim Davies, Martin Dennys, Leila Elbahy, Tom Fowler, Sue Hill, Tim Hubbard, Luke Jostins, Nick Maltby, Jeanna Mahon-Pearson, Gil McVean, Katrina Nevin-Ridley, Matthew Parker, Vivienne Parry, Augusto Rendon, Laura E. Riley, Clare Turnbull, Kerrie Woods

    Published 2019
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  9. 9
    Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

    Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis by Jimmy Z. Liu, Mohamed A. Almarri, Daniel J. Gaffney, George Mells, Luke Jostins, Heather J. Cordell, Samantha Ducker, Darren B. Day, Michael A. Heneghan, James Neuberger, Peter T. Donaldson, Andrew Bathgate, Andrew K. Burroughs, Mervyn H. Davies, D. I. Jones, Graeme Alexander, Jeffrey C. Barrett, Richard Sandford, Carl A. Anderson

    Published 2012
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  10. 10
    Metabolomic and genomic prediction of common diseases in 477,706 participants in three national biobanks

    Metabolomic and genomic prediction of common diseases in 477,706 participants in three national biobanks by Jeffrey C. Barrett, Tõnu Esko, Krista Fischer, Luke Jostins-Dean, Pekka Jousilahti, Heli Julkunen, Tuija Jääskeläinen, Nurlan Kerimov, Sini Kerminen, Anastassia Kolde, Harri Koskela, Jaanika Kronberg, Sara Lundgren, Annamari Lundqvist, Valtteri Mäkelä, Kristian Nybo, Markus Perola, Veikko Salomaa, Kirsten Schut, Maiju Soikkeli, Pasi Soininen, Mika Tiainen, Taavi Tillmann, Peter Würtz

    Published 2023
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  11. 11
    Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2

    Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2 by Subhankar Mukhopadhyay, Eva Heinz, Immacolata Porreca, Kaur Alasoo, Amy Yeung, Huei-Ting Yang, Tobias Schwerd, Jessica L. Forbester, Christine Hale, Chukwuma A. Agu, Yoon Ha Choi, Julia Rodrigues, Melania Capitani, Luke Jostins-Dean, David Thomas, Simon Travis, Daniel J. Gaffney, William C. Skarnes, Nicholas R. Thomson, Holm H. Uhlig, Gordon Dougan, Fiona Powrie

    Published 2019
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  12. 12
    Metabolomic and genomic prediction of common diseases in 700,217 participants in three national biobanks

    Metabolomic and genomic prediction of common diseases in 700,217 participants in three national biobanks by Jeffrey C. Barrett, Tõnu Esko, Krista Fischer, Luke Jostins-Dean, Pekka Jousilahti, Heli Julkunen, Tuija Jääskeläinen, Antti J. Kangas, Nurlan Kerimov, Sini Kerminen, Anastassia Kolde, Harri Koskela, Jaanika Kronberg, Sara Lundgren, Annamari Lundqvist, Valtteri Mäkelä, Kristian Nybo, Markus Perola, Veikko Salomaa, Kirsten Schut, Maiju Soikkeli, Pasi Soininen, Mika Tiainen, Taavi Tillmann, Peter Würtz

    Published 2024
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  13. 13
    Resolving <i>TYK2</i> locus genotype-to-phenotype differences in autoimmunity

    Resolving <i>TYK2</i> locus genotype-to-phenotype differences in autoimmunity by Calliope A. Dendrou, Adrián Cortés, Lydia Shipman, Hayley G. Evans, Kathrine E. Attfield, Luke Jostins, Thomas R. Barber, Gurman Kaur, Subita Balaram Kuttikkatte, Oliver Leach, Christiane Desel, Soren L. Faergeman, Jane Cheeseman, Matt J. Neville, Stephen Sawcer, Alastair Compston, Adam R. Johnson, Christine Everett, John I. Bell, Fredrik Karpe, Mark Ultsch, Charles Eigenbrot, Gil McVean, Lars Fugger

    Published 2016
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  14. 14
    High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

    High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis by Philippe Goyette, Gabrielle Boucher, Dermot Mallon, Eva Ellinghaus, Luke Jostins, Hailiang Huang, Stephan Ripke, Elena S. Gusareva, Vito Annese, Stephen L. Hauser, Jorge R. Oksenberg, Ingo Thomsen, Stephen Leslie, Mark J. Daly, Kristel Van Steen, Richard H. Duerr, Jeffrey C. Barrett, Dermot McGovern, L. Philip Schumm, James A. Traherne, Mary Carrington, Vasilis Kosmoliaptsis, Tom H. Karlsen, André Franke, John D. Rioux

    Published 2015
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  15. 15
    Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7

    Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7 by Yang Luo, Katrina M. de Lange, Luke Jostins, Loukas Moutsianas, Joshua C. Randall, Nicholas A. Kennedy, Christopher A Lamb, Shane McCarthy, Tariq Ahmad, Cathryn Edwards, Eva Serra, Ailsa Hart, C J Hawkey, John Mansfield, Craig Mowat, William G. Newman, Sam Nichols, Martin Pollard, Jack Satsangi, Alison Simmons, Mark Tremelling, Holm H. Uhlig, David C. Wilson, James Lee, Natalie J. Prescott, Charlie W. Lees, Christopher G. Mathew, Miles Parkes, Jeffrey C. Barrett, Carl A. Anderson

    Published 2017
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  16. 16
    Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

    Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations by Gavin Band, Si Quang Le, Luke Jostins, Matti Pirinen, Katja Kivinen, Muminatou Jallow, Fatoumatta Sisay-Joof, Kalifa Bojang, Margaret Pinder, Giorgio Sirugo, David J. Conway, Vysaul Nyirongo, David Kachala, Malcolm E. Molyneux, Terrie E. Taylor, Carolyne Ndila, Norbert Peshu, Kevin Marsh, Thomas N. Williams, Daniel Alcock, Robert Andrews, Sarah Edkins, Emma Gray, Christina Hubbart, Anna E. Jeffreys, Kate Rowlands, Kathrin Schuldt, Taane G. Clark, Kerrin S. Small, Yik Ying Teo, Dominic Kwiatkowski, Kirk A. Rockett, Jeffrey C. Barrett, Chris C. A. Spencer

    Published 2013
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  17. 17
    Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

    Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease by Katrina M. de Lange, Loukas Moutsianas, James Lee, Christopher A Lamb, Yang Luo, Nicholas A. Kennedy, Luke Jostins, Daniel L Rice, Javier Gutierrez‐Achury, Sun‐Gou Ji, Graham Heap, Elaine R. Nimmo, Cathryn Edwards, Paul Henderson, Craig Mowat, Jeremy Sanderson, Jack Satsangi, Alison Simmons, David C. Wilson, Mark Tremelling, Ailsa Hart, Christopher G. Mathew, William G. Newman, Miles Parkes, Charlie W. Lees, Holm H. Uhlig, C J Hawkey, Natalie J. Prescott, Tariq Ahmad, John Mansfield, Carl A. Anderson, Jeffrey C. Barrett

    Published 2017
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  18. 18
    An Integrated Taxonomy for Monogenic Inflammatory Bowel Disease

    An Integrated Taxonomy for Monogenic Inflammatory Bowel Disease by Chrissy Bolton, Christopher S. Smillie, Sumeet Pandey, Rasa Elmentaite, Gabrielle Wei, Carmen Argmann, Dominik Aschenbrenner, Kylie R. James, Dermot McGovern, Marina Macchi, Judy H. Cho, Dror S. Shouval, Jochen Kammermeier, Sibylle Koletzko, Krithika Bagalopal, Melania Capitani, Athena Cavounidis, Elisabete Pires, Carl Weidinger, James McCullagh, Peter D. Arkwright, Wolfram Haller, Britta Siegmund, Lauren Peters, Luke Jostins, Simon Travis, Carl A. Anderson, Scott B. Snapper, Christoph Klein, Eric E. Schadt, Matthias Zilbauer, Ramnik J. Xavier, Sarah A. Teichmann, Aleixo M. Muise, Aviv Regev, Holm H. Uhlig

    Published 2021
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  19. 19
    Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

    Negligible impact of rare autoimmune-locus coding-region variants on missing heritability by Karen A. Hunt, Vanisha Mistry, Nicholas Bockett, Tariq Ahmad, Maria Ban, Juliet N. Barker, Jeffrey C. Barrett, Hannah Blackburn, Stephan Brand, Oliver S. Burren, Francesca Capon, Alastair Compston, Stephen Gough, Luke Jostins, Yong Kong, James Lee, Monkol Lek, Daniel G. MacArthur, John Mansfield, Christopher G. Mathew, Charles A. Mein, Muddassar M. Mirza, Sarah Nutland, Suna Önengüt-Gümüşcü, Efterpi Papouli, Miles Parkes, Stephen S. Rich, Steven Sawcer, Jack Satsangi, Matthew J. Simmonds, Richard C. Trembath, Neil Walker, Eva Wozniak, John A. Todd, Michael A. Simpson, Vincent Plagnol, David A. van Heel

    Published 2013
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  20. 20
    Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

    Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations by Jimmy Z. Liu, Suzanne van Sommeren, Hailiang Huang, Siew C. Ng, Rudi Alberts, Atsushi Takahashi, Stephan Ripke, James Lee, Luke Jostins-Dean, Tejas Shah, Shifteh Abedian, Jae Hee Cheon, Judy H. Cho, Naser Ebrahim Daryani, Lude Franke, Yuta Fuyuno, Ailsa Hart, Ramesh C. Juyal, Garima Juyal, Won Ho Kim, Andrew P. Morris, Hossein Poustchi, William G. Newman, Vandana Midha, Timothy R. Orchard, Homayon Vahedi, Ajit Sood, Joseph J.�Y. Sung, Reza Malekzadeh, Harm-Jan Westra, Keiko Yamazaki, Suk-Kyun Yang, Jeffrey C. Barrett, Andre Franke, Behrooz Z Alizadeh, Miles Parkes, B.K. Thelma, Mark Daly, Michiaki Kubo, Carl A. Anderson, Rinse K. Weersma

    Published 2015
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