检索结果 - Lukas Villiger

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  1. 1
    In vivo prime editing of a metabolic liver disease in mice

    In vivo prime editing of a metabolic liver disease in mice 由 Desirée Böck, Tanja Rothgangl, Lukas Villiger, Lukas Schmidheini, Mai Matsushita, Nicolas Mathis, Eleonora Ioannidi, Nicole Rimann, Hiu Man Grisch‐Chan, Susanne Kreutzer, Zacharias Kontarakis, Manfred Köpf, Beat Thöny, Gerald Schwank

    出版 2022
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  2. 2
    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance 由 Till Ringel, Nina Frey, Femke Ringnalda, Sharan Janjuha, Sarah Cherkaoui, Stefan Butz, Sumana Srivatsa, Martin Pirkl, Giancarlo Russo, Lukas Villiger, Gerhard Rogler, Hans Clevers, Niko Beerenwinkel, Nicola Zamboni, Tuncay Baubec, Gerald Schwank

    出版 2020
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  3. 3
    In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA

    In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA 由 Lukas Villiger, Tanja Rothgangl, Dominik Witzigmann, Rurika Oka, Paulo J.C. Lin, Weihong Qi, Sharan Janjuha, Christian Berk, Femke Ringnalda, Mitchell Beattie, Markus Stoffel, Beat Thöny, Jonathan Hall, Hubert Rehrauer, Ruben van Boxtel, Ying K. Tam, Gerald Schwank

    出版 2021
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  4. 4
    Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy

    Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label therapy 由 Christian Hirt, Tijmen H. Booij, Linda Grob, Patrik Simmler, Nora C. Toussaint, David Keller, Doreen Taube, Vanessa Ludwig, Alexander Goryachkin, Chantal Pauli, Daniela Lenggenhager, Daniel J. Stekhoven, Christian U. Stirnimann, Katharina Endhardt, Femke Ringnalda, Lukas Villiger, Alexander Siebenhüner, Sofia Karkampouna, Marta De Menna, Janette Beshay, Hagen Klett, Marianna Kruithof‐de Julio, Julia Schüler, Gerald Schwank

    出版 2022
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  5. 5
    Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

    Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases 由 Matthew T. N. Yarnall, Eleonora Ioannidi, Cian Schmitt-Ulms, Rohan N. Krajeski, Justin Lim, Lukas Villiger, Wenyuan Zhou, Kaiyi Jiang, Sofya K. Garushyants, Nathaniel Roberts, Liyang Zhang, Christopher A. Vakulskas, John Walker, Anastasia P. Kadina, Adrianna E. Zepeda, Kevin Holden, Hong Ma, Jun Xie, Guangping Gao, Lander Foquet, Greg Bial, Sara K. Donnelly, Yoshinari Miyata, Daniel R. Radiloff, Jordana M. Henderson, Andrew Ujita, Omar O. Abudayyeh, Jonathan S. Gootenberg

    出版 2022
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  6. 6
    In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

    In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels 由 Tanja Rothgangl, Melissa K. Dennis, Paulo J.C. Lin, Rurika Oka, Dominik Witzigmann, Lukas Villiger, Weihong Qi, Martina Hruzova, Lucas Kissling, Daniela Lenggenhager, Costanza Borrelli, Sabina Egli, Nina Frey, Noëlle Bakker, John Walker, Anastasia P. Kadina, Denis V. Victorov, Martin Pačesa, Susanne Kreutzer, Zacharias Kontarakis, Andreas E. Moor, Martin Jínek, Drew Weissman, Markus Stoffel, Ruben van Boxtel, Kevin Holden, Norbert Pardi, Beat Thöny, Johannes Häberle, Ying K. Tam, Sean C. Semple, Gerald Schwank

    出版 2021
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  7. 7
    3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial

    3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial 由 Carel W. le Roux, Arne Astrup, Ken Fujioka, Frank L. Greenway, David Lau, Luc Van Gaal, Rafael Violante Ortíz, John Wilding, Trine Vang Skjøth, Linda Shapiro Manning, F. Xavier Pi‐Sunyer, A. Hamann, Alain Barakat, Matthias Blüher, Thomas Linn, Andrea Mölle, Alexander Segner, Petra Stübler, Regina Tosch-Sisting, Furio Pacini, Ferruccio Santini, Giulio Marchesini, Carlo Maria Rotella, Cecilia Invitti, Roberto Vettor, Silvio Buscemi, Pedro Mezquita Raya, Felipe Casanueva Freijoo, Ramón Gomis de Barbará, Raffaele Carraro, Enrique Romero Bobillo, Carmen de la Cuesta, Csaba Farsang, Albert Császár, Barbara Zahorska‐Markiewicz, Danuta Pupek-Musialik, Edward Franek, Lucyna Ostrowska, Magdalena Olszanecka‐Glinianowicz, Nebojša Lalić, Dragan Micić, Bernhard Ludvik, Bernhard Paulweber, Rudolf Prager, André Scheen, Luc Van Gaal, Arne Astrup, Kjeld Hermansen, Sten Madsbad, Aila Rissanen, Sakari Nieminen, Markku J. Savolainen, Michel Krempf, Monique Romon, M. Laville, Michel Marre, R Mira, Francis Finucane, Aletha Veenendaal, Frank van Berkum, Solrun Johannsson-Vidarsdóttir, Vivienne Van de Walle, Eelco W. Meesters, Jøran Hjelmesæth, Tor Ole Klemsdal, Bård Kulseng, Birgit Bach-Kliegel, Kurt Laederach, Lukas Villiger, Alain Golay, Stefan Bilz, Thozhukat Sathyapalan, Stephen C. Bain, Sudhesh Kumar, Carel Wynard Le Roux, Michael E. J. Lean, Barbara McGowan, Tariq Rehman, John Wilding, Gary Wittert, Ian Caterson, Joeseph Proietto, John Prins, Bruno Geloneze Neto, Jorge Luiz Gross, Antônio Roberto Chacra, Alfredo Halpern, Henrique Suplicy, Francis Chun Chung Chow, Hemant Thacker, Manoj Chadha, Hemaraj Chandalia, AG Unnikrishnan, Sanjay Kalra, Neeta Deshpande, Minakshi Shunmugavelu, Vaishali Deshmukh, Maximo Maislos, G. Lieberman, Ilan Shimon

    出版 2017
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