Suchergebnisse - Lukas C. Amler

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  1. 1
    Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA.

    Amplified N-myc in human neuroblastoma cells is often arranged as clustered tandem repeats of differently recombined DNA. von Lukas C. Amler, M. Schwab

    Veröffentlicht 1989
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  2. 2
    Genomic instability in Ip and human malignancies

    Genomic instability in Ip and human malignancies von Manfred Schwab, Christian Praml, Lukas C. Amler

    Veröffentlicht 1996
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  3. 3
    Relationship between HER2 expression and efficacy with first-line trastuzumab emtansine compared with trastuzumab plus docetaxel in TDM4450g: a randomized phase II study of patients with previously untreated HER2-positive metastatic breast cancer

    Relationship between HER2 expression and efficacy with first-line trastuzumab emtansine compared with trastuzumab plus docetaxel in TDM4450g: a randomized phase II study of patient... von Edith A. Perez, Sara A. Hurvitz, Lukas C. Amler, Kirsten Mundt, Vivian Ng, Ellie Guardino, Luca Gianni

    Veröffentlicht 2014
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  4. 4
    Dual Targeting of EGFR and HER3 with MEHD7945A Overcomes Acquired Resistance to EGFR Inhibitors and Radiation

    Dual Targeting of EGFR and HER3 with MEHD7945A Overcomes Acquired Resistance to EGFR Inhibitors and Radiation von Shyhmin Huang, Chunrong Li, Eric A. Armstrong, Chimera R. Peet, Jarob Saker, Lukas C. Amler, Mark X. Sliwkowski, Paul M. Harari

    Veröffentlicht 2012
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  5. 5
    Proteomic analysis of breast cancer molecular subtypes and biomarkers of response to targeted kinase inhibitors using reverse-phase protein microarrays

    Proteomic analysis of breast cancer molecular subtypes and biomarkers of response to targeted kinase inhibitors using reverse-phase protein microarrays von Zachary Boyd, Qun Wu, Carol O’Brien, Jill M. Spoerke, Heidi Savage, Paul J. Fielder, Lukas C. Amler, Yibing Yan, Mark R. Lackner

    Veröffentlicht 2008
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  6. 6
    A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis

    A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis von Nicholas Dompe, Celina Sanchez Rivers, Li Li, Shaun Cordes, Martin Schwickart, Elizabeth A. Punnoose, Lukas C. Amler, Somasekar Seshagiri, Jerry Tang, Zora Modrušan, David P. Davis

    Veröffentlicht 2011
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  7. 7
    Functional Genomics Identifies ABCC3 as a Mediator of Taxane Resistance in HER2-Amplified Breast Cancer

    Functional Genomics Identifies ABCC3 as a Mediator of Taxane Resistance in HER2-Amplified Breast Cancer von Carol O’Brien, Guy Cavet, Ajay Pandita, Xiaolan Hu, Lauren E. Haydu, Sankar Mohan, Karen Toy, Celina Sanchez Rivers, Zora Modrušan, Lukas C. Amler, Mark R. Lackner

    Veröffentlicht 2008
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  8. 8
    Molecular Biomarker Analyses Using Circulating Tumor Cells

    Molecular Biomarker Analyses Using Circulating Tumor Cells von Elizabeth A. Punnoose, Siminder Atwal, Jill M. Spoerke, Heidi Savage, Ajay Pandita, Ru‐Fang Yeh, Andrea Pirzkall, Bernard M. Fine, Lukas C. Amler, Daniel S. Chen, Mark R. Lackner

    Veröffentlicht 2010
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  9. 9
    Changes in 18F-Fluorodeoxyglucose and 18F-Fluorodeoxythymidine Positron Emission Tomography Imaging in Patients with Non–Small Cell Lung Cancer Treated with Erlotinib

    Changes in 18F-Fluorodeoxyglucose and 18F-Fluorodeoxythymidine Positron Emission Tomography Imaging in Patients with Non–Small Cell Lung Cancer Treated with Erlotinib von Linda Mileshkin, Rodney J. Hicks, Brett Hughes, Paul Mitchell, Veena Charu, Barbara J. Gitlitz, David Macfarlane, Benjamin Solomon, Lukas C. Amler, Wei Yu, Andrea Pirzkall, Bernard M. Fine

    Veröffentlicht 2011
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  10. 10
    Evaluation of Circulating Tumor Cells and Circulating Tumor DNA in Non–Small Cell Lung Cancer: Association with Clinical Endpoints in a Phase II Clinical Trial of Pertuzumab and Erlotinib

    Evaluation of Circulating Tumor Cells and Circulating Tumor DNA in Non–Small Cell Lung Cancer: Association with Clinical Endpoints in a Phase II Clinical Trial of Pertuzumab and Er... von Elizabeth A. Punnoose, Siminder Atwal, Weiqun Liu, Rajiv Raja, Bernard M. Fine, Brett Hughes, Rodney J. Hicks, Garret M. Hampton, Lukas C. Amler, Andrea Pirzkall, Mark R. Lackner

    Veröffentlicht 2012
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  11. 11
    Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer

    Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer von Jiping Zha, Carol O’Brien, Heidi Savage, Ling‐Yuh Huw, Fiona Zhong, Leanne Berry, Gail D. Lewis Phillips, Elizabeth Luis, Guy Cavet, Xiaolan Hu, Lukas C. Amler, Mark R. Lackner

    Veröffentlicht 2009
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  12. 12
    High-Throughput Detection of Clinically Relevant Mutations in Archived Tumor Samples by Multiplexed PCR and Next-Generation Sequencing

    High-Throughput Detection of Clinically Relevant Mutations in Archived Tumor Samples by Multiplexed PCR and Next-Generation Sequencing von Richard Bourgon, Shan Lu, Yibing Yan, Mark R. Lackner, Weiru Wang, Victor Weigman, David Wang, Yinghui Guan, Lisa Ryner, Hartmut Koeppen, Rajesh Patel, Garret M. Hampton, Lukas C. Amler, Yulei Wang

    Veröffentlicht 2014
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  13. 13
    Upregulation of Periostin and Reactive Stroma Is Associated with Primary Chemoresistance and Predicts Clinical Outcomes in Epithelial Ovarian Cancer

    Upregulation of Periostin and Reactive Stroma Is Associated with Primary Chemoresistance and Predicts Clinical Outcomes in Epithelial Ovarian Cancer von Lisa Ryner, Yinghui Guan, Ron Firestein, Yuanyuan Xiao, Younjeong Choi, Christina Rabe, Shan Lu, Eloisa Fuentes, Ling‐Yuh Huw, Mark R. Lackner, Ling Fu, Lukas C. Amler, Carlos Bais, Yulei Wang

    Veröffentlicht 2015
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  14. 14
    A Phase II Study of Trastuzumab Emtansine in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer Who Were Previously Treated With Trastuzumab, Lapatinib, an Anthracycline, a Taxane, and Capecitabine

    A Phase II Study of Trastuzumab Emtansine in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer Who Were Previously Treated With Trastuzumab,... von Ian E. Krop, Patricia LoRusso, Kathy D. Miller, Shanu Modi, Denise A. Yardley, Gladys Rodriguez, Ellie Guardino, Michael W. Lu, Maoxia Zheng, Sandhya Girish, Lukas C. Amler, Eric P. Winer, Hope S. Rugo

    Veröffentlicht 2012
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  15. 15
    Predictive Biomarkers of Sensitivity to the Phosphatidylinositol 3′ Kinase Inhibitor GDC-0941 in Breast Cancer Preclinical Models

    Predictive Biomarkers of Sensitivity to the Phosphatidylinositol 3′ Kinase Inhibitor GDC-0941 in Breast Cancer Preclinical Models von Carol O’Brien, Jeffrey J. Wallin, Deepak Sampath, Debraj GuhaThakurta, Heidi Savage, Elizabeth A. Punnoose, Jane Guan, Leanne Berry, Wei Wei Prior, Lukas C. Amler, Marcia Belvin, Lori S. Friedman, Mark R. Lackner

    Veröffentlicht 2010
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  16. 16
    Epithelial versus Mesenchymal Phenotype Determines <i>In vitro</i> Sensitivity and Predicts Clinical Activity of Erlotinib in Lung Cancer Patients

    Epithelial versus Mesenchymal Phenotype Determines <i>In vitro</i> Sensitivity and Predicts Clinical Activity of Erlotinib in Lung Cancer Patients von Robert L. Yauch, Thomas Januario, David A. Eberhard, Guy Cavet, Wenjing Zhu, Ling Fu, Thinh Q. Pham, Robert Soriano, Jeremy Stinson, Somasekar Seshagiri, Zora Modrušan, Chin‐Yu Lin, Vincent O’Neill, Lukas C. Amler

    Veröffentlicht 2005
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  17. 17
    A role for FOXO1 in BCR–ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia

    A role for FOXO1 in BCR–ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia von Marie-Claire Wagle, Anna M. Eiring, Matthew Wongchenko, Shaoyong Lu, Yinghui Guan, Yulei Wang, Mark R. Lackner, Lukas C. Amler, Garret M. Hampton, Michael W. Deininger, Thomas O’Hare, Ying-Li WuHua Yan

    Veröffentlicht 2016
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  18. 18
    Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer

    Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for t... von Giampaolo Bianchini, Astrid Kiermaier, Giulia Bianchi, Young‐Hyuck Im, Tadeusz Pieńkowski, Mei-Ching Liu, Ling‐Ming Tseng, Mitch Dowsett, Lila Zabaglo, S Kirk, Tania Szado, Jennifer Eng‐Wong, Lukas C. Amler, Pinuccia Valagussa, Luca Gianni

    Veröffentlicht 2017
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  19. 19
    Somatic Mutations Lead to an Oncogenic Deletion of Met in Lung Cancer

    Somatic Mutations Lead to an Oncogenic Deletion of Met in Lung Cancer von Monica Kong-Beltran, Somasekar Seshagiri, Jiping Zha, Wenjing Zhu, Kaumudi Bhawe, Nerissa Mendoza, Thomas Holcomb, Kanan Pujara, Jeremy Stinson, Ling Fu, Christophe Severin, Linda Rangell, Ralph Schwall, Lukas C. Amler, Dineli Wickramasinghe, Robert L. Yauch

    Veröffentlicht 2006
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  20. 20
    Clinical Activity of Gemcitabine Plus Pertuzumab in Platinum-Resistant Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

    Clinical Activity of Gemcitabine Plus Pertuzumab in Platinum-Resistant Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer von Sharmila Makhija, Lukas C. Amler, D. Glenn, Frederick R. Ueland, Michael A. Gold, Don S. Dizon, Virginia Paton, Chin‐Yu Lin, Thomas Januario, Kimmie Ng, Andreas C. Strauß, Stephen M. Kelsey, Mark X. Sliwkowski, Ursula A. Matulonis

    Veröffentlicht 2009
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