Výsledky vyhledávání - Luis Concha‐Marambio

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  1. 1
    Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid

    Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid Autor Luis Concha‐Marambio, Sandra Pritzkow, Mohammad Shahnawaz, Carly M. Farris, Claudio Soto

    Vydáno 2023
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  2. 2
    Efficient prion disease transmission through common environmental materials

    Efficient prion disease transmission through common environmental materials Autor Sandra Pritzkow, Rodrigo Morales, Adam Lyon, Luis Concha‐Marambio, Akihiko Urayama, Claudio Soto

    Vydáno 2018
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  3. 3
    Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease

    Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease Autor Luis Concha‐Marambio, Sandra Pritzkow, Fabio Moda, Fabrizio Tagliavini, James W. Ironside, Paul E. Schulz, Claudio Soto

    Vydáno 2016
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  4. 4
    Association of αS-SAA kinetics with clinical scores in the clinical spectrum of Parkinson's disease

    Association of αS-SAA kinetics with clinical scores in the clinical spectrum of Parkinson's disease Autor G. Bellomo, Federico Paolini Paoletti, Lorenzo Gaetani, Andrea Toja, Yihua Ma, Carly M. Farris, Luis Concha‐Marambio, Lucilla Parnetti

    Vydáno 2025
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  5. 5
    The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo

    The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo Autor Kyung‐Won Park, Gyoung Eun Kim, Rodrigo Morales, Fabio Moda, Inés Moreno‐González, Luis Concha‐Marambio, Amy S. Lee, Claudio Hetz, Claudio Soto

    Vydáno 2017
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  6. 6
    Association of CSF α‐synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer's Disease Neuroimaging Initiative study

    Association of CSF α‐synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer's Disease Neuroimaging Initiative study... Autor Duygu Tosun, Zachary Hausle, Pamela Thropp, Luis Concha‐Marambio, Jennifer Lamoureux, Russ Lebovitz, Leslie M. Shaw, Andrew B. Singleton, Michael W. Weiner, Cornelis Blauwendraat

    Vydáno 2024
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  7. 7
    Investigating alpha‐synuclein co‐pathology in Alzheimer's disease by means of cerebrospinal fluid alpha‐synuclein seed amplification assay

    Investigating alpha‐synuclein co‐pathology in Alzheimer's disease by means of cerebrospinal fluid alpha‐synuclein seed amplification assay Autor G. Bellomo, Andrea Toja, Federico Paolini Paoletti, Yihua Ma, Carly M. Farris, Lorenzo Gaetani, Nicola Salvadori, Davide Chiasserini, Anna Lidia Wojdała, Luis Concha‐Marambio, Lucilla Parnetti

    Vydáno 2024
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  8. 8
    Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression

    Seed Amplification Assay to Diagnose Early Parkinson's and Predict Dopaminergic Deficit Progression Autor Luis Concha‐Marambio, Carly M. Farris, Bret Holguin, Yihua Ma, John Seibyl, Marco J. Russo, Un Jung Kang, Samantha J. Hutten, Kalpana Merchant, Mohammad Shahnawaz, Claudio Soto

    Vydáno 2021
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  9. 9
    Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study

    Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study Autor Kenneth Marek, David Russell, Luis Concha‐Marambio, Seung Ho Choi, Danna Jennings, Michael C. Brumm, Christopher S. Coffey, Ethan Brown, John Seibyl, Matthew Stern, Claudio Soto, Andrew Siderowf

    Vydáno 2025
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  10. 10
    α-Synuclein seed amplification assay as a diagnostic tool for parkinsonian disorders

    α-Synuclein seed amplification assay as a diagnostic tool for parkinsonian disorders Autor Bárbara Fernandes Gomes, Carly M. Farris, Yihua Ma, Luis Concha‐Marambio, Russ Lebovitz, Bengt Nellgård, Keti Dalla, Julius Constantinescu, Radu Constantinescu, Johan Gobom, Ulf Andréasson, Henrik Zetterberg, Kaj Blennow

    Vydáno 2023
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  11. 11
    Prions in the Urine of Patients with Variant Creutzfeldt–Jakob Disease

    Prions in the Urine of Patients with Variant Creutzfeldt–Jakob Disease Autor Fabio Moda, Pierluigi Gambetti, Silvio Notari, Luis Concha‐Marambio, Marcella Catania, Kyung-Won Park, Emanuela Maderna, Silvia Suardi, Stéphane Haı̈k, J.-P. Brandel, James W. Ironside, Richard Knight, Fabrizio Tagliavini, Claudio Soto

    Vydáno 2014
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  12. 12
    Accurate Detection of <scp>α‐Synuclein</scp> Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson's Disease in the DeNovo Parkinson (DeNoPa) Cohort

    Accurate Detection of <scp>α‐Synuclein</scp> Seeds in Cerebrospinal Fluid from Isolated Rapid Eye Movement Sleep Behavior Disorder and Patients with Parkinson's Disease in the DeNo... Autor Luis Concha‐Marambio, Sandrina Weber, Carly M. Farris, Mohammed Dakna, Elisabeth Lang, Tamara Wicke, Yihua Ma, Maritta Starke, Jens Ebentheuer, Friederike Sixel‐Döring, Maria‐Lucia Muntean, Sebastian Schade, Claudia Trenkwalder, Claudio Soto, Brit Mollenhauer

    Vydáno 2023
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  13. 13
    α‐Synuclein Seed Amplification in <scp>CSF</scp> and Brain from Patients with Different Brain Distributions of Pathological α‐Synuclein in the Context of Co‐Pathology and <scp>Non‐LBD</scp> Diagnoses

    α‐Synuclein Seed Amplification in <scp>CSF</scp> and Brain from Patients with Different Brain Distributions of Pathological α‐Synuclein in the Context of Co‐Pathology and <scp>Non‐... Autor Moriah R. Arnold, David G. Coughlin, Barbara H. Brumbach, Denis S. Smirnov, Luis Concha‐Marambio, Carly M. Farris, Yihua Ma, Yongya Kim, Edward N. Wilson, Jeffrey Kaye, Annie Hiniker, Randy Woltjer, Douglas Galasko, Joseph F. Quinn

    Vydáno 2022
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  14. 14
    Clinicopathological correlation of cerebrospinal fluid alpha‐synuclein seed amplification assay in a behavioral neurology autopsy cohort

    Clinicopathological correlation of cerebrospinal fluid alpha‐synuclein seed amplification assay in a behavioral neurology autopsy cohort Autor Niyatee Samudra, D. Luke Fischer, Steven Lenio, Argentina Lario Lago, Peter A. Ljubenkov, Julio C. Rojas, William W. Seeley, Salvatore Spina, Adam M. Staffaroni, Jonathan Tablante, Fattin Wekselman, Jennifer Lamoureux, Luis Concha‐Marambio, Lea T. Grinberg, Adam L. Boxer, Lawren VandeVrede

    Vydáno 2024
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  15. 15
    High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease

    High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease Autor Marco J. Russo, Christina D. Orrù, Luis Concha‐Marambio, Simone Giaisi, Bradley R. Groveman, Carly M. Farris, Bret Holguin, Andrew G. Hughson, David-Erick Lafontant, Chelsea Caspell‐Garcia, Christopher S. Coffey, J Mollon, Samantha J. Hutten, Kalpana Merchant, Roland G. Heym, Claudio Soto, Byron Caughey, Un Jung Kang

    Vydáno 2021
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  16. 16
    Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays

    Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays Autor G. Bellomo, Silvia Paciotti, Luis Concha‐Marambio, Domenico Rizzo, Anna Lidia Wojdała, Davide Chiasserini, Leonardo Gatticchi, Linda Cerofolini, Stefano Giuntini, Chiara Maria Giulia De Luca, Yihua Ma, Carly M. Farris, Giuseppe Pieraccini, Sara Bologna, Marta Filidei, Enrico Ravera, Moreno Lelli, Fabio Moda, Marco Fragai, Lucilla Parnetti, Claudio Luchinat

    Vydáno 2023
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  17. 17
    Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial

    Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial Autor Pepijn Eijsvogel, Pinaki Misra, Luis Concha‐Marambio, Justin D. Boyd, Shuang Ding, Lauren Fedor, Yueh-Ting Hsieh, Yu Sun, Madeline M. Vroom, Carly M. Farris, Yihua Ma, Marieke L. de Kam, Igor Radanović, Maurits F. J. M. Vissers, Dario Mirski, Ghazal Shareghi, Mohammad Shahnawaz, Wolfgang Singer, Philip H. C. Kremer, Geert Jan Groeneveld, Hui Jing Yu, Jean‐Cosme Dodart

    Vydáno 2024
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  18. 18
    Misfolded α‐synuclein co‐occurrence with Alzheimer's disease proteinopathy

    Misfolded α‐synuclein co‐occurrence with Alzheimer's disease proteinopathy Autor Erin M. Jonaitis, Karen MacLeod, Jennifer Lamoureux, Beckie Jeffers, Rachel Studer, John P. Middleton, Rachael E Wilson, Nathaniel A. Chin, Ozioma C. Okonkwo, Barbara B. Bendlin, Sanjay Asthana, Cynthia M. Carlsson, Catherine L. Gallagher, Bruce P. Hermann, Sean D. McEvoy, Gwendlyn Kollmorgen, Henrik Zetterberg, Luis Concha‐Marambio, Sterling C. Johnson, Russ Lebovitz, Rebecca E. Langhough

    Vydáno 2025
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  19. 19
    Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study

    Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study Autor Andrew Siderowf, Luis Concha‐Marambio, David-Erick Lafontant, Carly M. Farris, Yihua Ma, Paula A. Urenia, Hieu Nguyen, Roy N. Alcalay, Lana M. Chahine, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, John Seibyl, Tanya Simuni, Caroline M. Tanner, Daniel Weintraub, Aleksandar Videnović, Seung Ho Choi, Ryan Kurth, Chelsea Caspell‐Garcia, Christopher S. Coffey, Mark Frasier, Luís M. A. Oliveira, Samantha J. Hutten, Todd Sherer, Kenneth Marek, Claudio Soto

    Vydáno 2023
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  20. 20
    Neuronal alpha-Synuclein Disease integrated staging system performance in PPMI, PASADENA, and SPARK baseline cohorts

    Neuronal alpha-Synuclein Disease integrated staging system performance in PPMI, PASADENA, and SPARK baseline cohorts Autor Tien Dam, Gennaro Pagano, Michael C. Brumm, Caroline Gochanour, Kathleen L. Poston, Daniel Weintraub, Lana M. Chahine, Christopher S. Coffey, Caroline M. Tanner, Catherine Kopil, Yuge Xiao, Sohini Chowdhury, Luis Concha‐Marambio, Peter DiBiaso, Tatiana Foroud, Mark Frasier, Danna Jennings, Karl Kieburtz, Kalpana Merchant, Brit Mollenhauer, Thomas J. Montine, Kelly Nudelman, John Seibyl, Todd Sherer, Andrew Singleton, Diane Stephenson, Matthew Stern, Claudio Soto, Eduardo Tolosa, Andrew Siderowf, Billy Dunn, Tanya Simuni, Kenneth Marek

    Vydáno 2024
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