檢索結果 - Lothar Gremer

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  1. 1
    A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family

    A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family 由 Alexander Eberth, Richard Lundmark, Lothar Gremer, Radovan Dvorský, Katja T. Koessmeier, Harvey T. McMahon, Mohammad Reza Ahmadian

    出版 2008
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  2. 2
    β-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor

    β-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor 由 Ewa A. Mirecka, Sophie Feuerstein, Lothar Gremer, Gunnar F. Schröder, Matthias Stoldt, Dieter Willbold, Wolfgang Hoyer

    出版 2016
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  3. 3
    Mechanistic Insights into Specificity, Activity, and Regulatory Elements of the Regulator of G-protein Signaling (RGS)-containing Rho-specific Guanine Nucleotide Exchange Factors (GEFs) p115, PDZ-RhoGEF (PRG), and Leukemia-associated RhoGEF (LARG)

    Mechanistic Insights into Specificity, Activity, and Regulatory Elements of the Regulator of G-protein Signaling (RGS)-containing Rho-specific Guanine Nucleotide Exchange Factors (... 由 Mamta Jaiswal, Lothar Gremer, Radovan Dvorský, Lars Christian Haeusler, Ion Cristian Cirstea, Katharina Uhlenbrock, Mohammad Reza Ahmadian

    出版 2011
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  4. 4
    Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth

    Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth 由 Michael M. Wördehoff, Hamed Shaykhalishahi, Luca Groß, Lothar Gremer, Matthias Stoldt, Alexander K. Buell, Dieter Willbold, Wolfgang Hoyer

    出版 2017
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  5. 5
    The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction

    The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction 由 Vladimir Peña, Michael Hothorn, Alexander Eberth, Nikolai Kaschau, Annabel Parret, Lothar Gremer, Fabien Bonneau, Mohammad Reza Ahmadian, Klaus Scheffzek

    出版 2008
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  6. 6
    Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders

    Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders 由 Lothar Gremer, Torsten Merbitz-Zahradnik, Radovan Dvorský, Ion Cristian Cirstea, Christian P. Kratz, Martin Zenker, Alfred Wittinghofer, Mohammad Reza Ahmadian

    出版 2010
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  7. 7
    Synthesis of the Rheb and K‐Ras4B GTPases

    Synthesis of the Rheb and K‐Ras4B GTPases 由 Yong‐Xiang Chen, Sebastian Koch, Katharina Uhlenbrock, Katrin Weise, Debapratim Das, Lothar Gremer, Luc Brunsveld, Alfred Wittinghofer, Roland Winter, Gemma Triola, Herbert Waldmann

    出版 2010
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  8. 8
    Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy

    Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy 由 Christine Röder, Nicola Vettore, Lena N. Mangels, Lothar Gremer, Raimond B. G. Ravelli, Dieter Willbold, Wolfgang Hoyer, Alexander K. Buell, Gunnar F. Schröder

    出版 2019
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  9. 9
    Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils

    Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils 由 Christine Röder, Tatsiana Kupreichyk, Lothar Gremer, Luisa U. Schäfer, Karunakar R. Pothula, Raimond B. G. Ravelli, Dieter Willbold, Wolfgang Hoyer, Gunnar F. Schröder

    出版 2020
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  10. 10
    Fibril structure of amyloid-β(1–42) by cryo–electron microscopy

    Fibril structure of amyloid-β(1–42) by cryo–electron microscopy 由 Lothar Gremer, Daniel Schölzel, C. Schenk, Elke Reinartz, Jörg Labahn, Raimond B. G. Ravelli, Markus Tusche, Carmen López‐Iglesias, Wolfgang Hoyer, Henrike Heise, Dieter Willbold, Gunnar F. Schröder

    出版 2017
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  11. 11
    Rho-kinase: regulation, (dys)function, and inhibition

    Rho-kinase: regulation, (dys)function, and inhibition 由 Ehsan Amin, Badri N. Dubey, Si-Cai Zhang, Lothar Gremer, Radovan Dvorský, Jens M. Moll, Mohamed S. Taha, Luitgard Nagel‐Steger, Roland P. Piekorz, Avril V. Somlyo, Mohammad Reza Ahmadian

    出版 2013
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  12. 12
    The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology

    The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology 由 Thomas van Groen, Sarah Schemmert, Oleksandr Brener, Lothar Gremer, Tamar Ziehm, Markus Tusche, Luitgard Nagel‐Steger, Inga Kadish, Elena Schartmann, Anne Elfgen, Dagmar Jürgens, Antje Willuweit, Janine Kutzsche, Dieter Willbold

    出版 2017
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  13. 13
    Preclinical Pharmacokinetic Studies of the Tritium Labelled D-Enantiomeric Peptide D3 Developed for the Treatment of Alzheimer´s Disease

    Preclinical Pharmacokinetic Studies of the Tritium Labelled D-Enantiomeric Peptide D3 Developed for the Treatment of Alzheimer´s Disease 由 Nan Jiang, Leonie H. E. Leithold, Julia Post, Tamar Ziehm, Jörg Mauler, Lothar Gremer, Markus Cremer, Elena Schartmann, N. Jon Shah, Janine Kutzsche, Karl‐Josef Langen, Jörg Breitkreutz, Dieter Willbold, Antje Willuweit

    出版 2015
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  14. 14
    Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer’s disease

    Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer’s disease 由 Mara Zielinski, Fernanda S. Peralta Reyes, Lothar Gremer, Sarah Schemmert, Benedikt Frieg, Luisa U. Schäfer, Antje Willuweit, L Donner, Margitta Elvers, Lars Nilsson, Stina Syvänen, Dag Sehlin, Martin Ingelsson, Dieter Willbold, Gunnar F. Schröder

    出版 2023
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  15. 15
    Origin of metastable oligomers and their effects on amyloid fibril self-assembly

    Origin of metastable oligomers and their effects on amyloid fibril self-assembly 由 Filip Hasecke, Tatiana Miti, Carlos J. Pérez-Rivera, Jeremy Barton, Daniel Schölzel, Lothar Gremer, Clara S. R. Grüning, Garrett Matthews, Georg Meisl, Tuomas P. J. Knowles, Dieter Willbold, Philipp Neudecker, Henrike Heise, Ghanim Ullah, Wolfgang Hoyer, Martin Muschol

    出版 2018
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  16. 16
    QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers

    QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers 由 Oleksandr Brener, Tina Dunkelmann, Lothar Gremer, Thomas van Groen, Ewa A. Mirecka, Inga Kadish, Antje Willuweit, Janine Kutzsche, Dagmar Jürgens, Stephan Rudolph, Markus Tusche, Patrick Bongen, Jörg Pietruszka, Filipp Oesterhelt, Karl‐Josef Langen, Hans‐Ulrich Demuth, Arnold Janssen, Wolfgang Hoyer, Susanne Aileen Funke, Luitgard Nagel‐Steger, Dieter Willbold

    出版 2015
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  17. 17
    A restricted spectrum of NRAS mutations causes Noonan syndrome

    A restricted spectrum of NRAS mutations causes Noonan syndrome 由 Ion Cristian Cirstea, Kerstin Kutsche, Radovan Dvorský, Lothar Gremer, Claudio Carta, Denise Horn, Amy E. Roberts, Francesca Romana Lepri, Torsten Merbitz-Zahradnik, Rainer König, Christian P. Kratz, Francesca Pantaleoni, Maria Lisa Dentici, Victoria A. Joshi, Raju Kucherlapati, Laura Mazzanti, Stefan Mundlos, Michael A. Patton, Margherita Silengo, Cesare Rossi, Giuseppe Zampino, Cristina Digilio, Liborio Stuppia, E Seemanová, L Pennacchio, Bruce D. Gelb, Bruno Dallapiccola, Alfred Wittinghofer, Mohammad Reza Ahmadian, Marco Tartaglia, Martin Zenker

    出版 2009
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