Suchergebnisse - Loren D. Walensky

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  1. 1
    BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore

    BAX unleashed: the biochemical transformation of an inactive cytosolic monomer into a toxic mitochondrial pore von Loren D. Walensky, Evripidis Gavathiotis

    Veröffentlicht 2011
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  2. 2
    Inositol 1,4,5-trisphosphate receptors selectively localized to the acrosomes of mammalian sperm.

    Inositol 1,4,5-trisphosphate receptors selectively localized to the acrosomes of mammalian sperm. von Loren D. Walensky, Solomon H. Snyder

    Veröffentlicht 1995
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  3. 3
    Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

    Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress von Loren D. Walensky, Gregory H. Bird

    Veröffentlicht 2014
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  4. 4
    Chemical Synthesis of Hydrocarbon‐Stapled Peptides for Protein Interaction Research and Therapeutic Targeting

    Chemical Synthesis of Hydrocarbon‐Stapled Peptides for Protein Interaction Research and Therapeutic Targeting von Gregory H. Bird, W. Christian Crannell, Loren D. Walensky

    Veröffentlicht 2011
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  5. 5
    Regulation of AMPA Receptor GluR1 Subunit Surface Expression by a 4.1N-Linked Actin Cytoskeletal Association

    Regulation of AMPA Receptor GluR1 Subunit Surface Expression by a 4.1N-Linked Actin Cytoskeletal Association von Lei Shen, Feng Liang, Loren D. Walensky, Richard L. Huganir

    Veröffentlicht 2000
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  6. 6
    Direct activation of full-length proapoptotic BAK

    Direct activation of full-length proapoptotic BAK von Elizaveta S. Leshchiner, Craig R. Braun, Geoffrey Bird, Loren D. Walensky

    Veröffentlicht 2013
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  7. 7
    Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains

    Chapter 22 Synthesis and Biophysical Characterization of Stabilized α‐Helices of BCL‐2 Domains von Gregory H. Bird, Federico Bernal, Kenneth L. Pitter, Loren D. Walensky

    Veröffentlicht 2008
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  8. 8
    The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer

    The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer von Michelle L. Stewart, Emiko Fire, Amy E. Keating, Loren D. Walensky

    Veröffentlicht 2010
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  9. 9
    Direct and selective small-molecule activation of proapoptotic BAX

    Direct and selective small-molecule activation of proapoptotic BAX von Evripidis Gavathiotis, Denis E. Reyna, Joseph A. Bellairs, Elizaveta S. Leshchiner, Loren D. Walensky

    Veröffentlicht 2012
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  10. 10
    Reactivation of the p53 Tumor Suppressor Pathway by a Stapled p53 Peptide

    Reactivation of the p53 Tumor Suppressor Pathway by a Stapled p53 Peptide von Federico Bernal, Andrew Tyler, Stanley J. Korsmeyer, Loren D. Walensky, Gregory L. Verdine

    Veröffentlicht 2007
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  11. 11
    BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX

    BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX von Evripidis Gavathiotis, Denis E. Reyna, Marguerite L. Davis, Gregory H. Bird, Loren D. Walensky

    Veröffentlicht 2010
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  12. 12
    Evaluation and critical assessment of putative MCL-1 inhibitors

    Evaluation and critical assessment of putative MCL-1 inhibitors von Shankar Varadarajan, Meike Vogler, Michael Butterworth, David Dinsdale, Loren D. Walensky, Gerald M. Cohen

    Veröffentlicht 2013
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  13. 13
    Cloning and Characterization of 4.1G (EPB41L2), a New Member of the Skeletal Protein 4.1 (EPB41) Gene Family

    Cloning and Characterization of 4.1G (EPB41L2), a New Member of the Skeletal Protein 4.1 (EPB41) Gene Family von Mireya Parra, Philippe Gascard, Loren D. Walensky, Solomon H. Snyder, Narla Mohandas, John G. Conboy

    Veröffentlicht 1998
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  14. 14
    Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies

    Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies von Greg H. Bird, Evripidis Gavathiotis, James L. LaBelle, Samuel G. Katz, Loren D. Walensky

    Veröffentlicht 2013
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  15. 15
    Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting

    Mechanistic validation of a clinical lead stapled peptide that reactivates p53 by dual HDM2 and HDMX targeting von Franziska Wachter, Ann M. Morgan, Marina Godes, Rida Mourtada, Gregory H. Bird, Loren D. Walensky

    Veröffentlicht 2016
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  16. 16
    Odorant Receptors and Desensitization Proteins Colocalize in Mammalian Sperm

    Odorant Receptors and Desensitization Proteins Colocalize in Mammalian Sperm von Loren D. Walensky, A. Jane Roskams, R.J. Lefkowitz, Solomon H. Snyder, Gabriele V. Ronnett

    Veröffentlicht 1995
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  17. 17
    BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress

    BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress von Marcos A. Carpio, Michael Michaud, Wenping Zhou, Jill K. Fisher, Loren D. Walensky, Samuel G. Katz

    Veröffentlicht 2015
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  18. 18
    Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

    Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics von Anthony Letai, Michael C. Bassik, Loren D. Walensky, Mia D. Sorcinelli, Solly Weiler, Stanley J. Korsmeyer

    Veröffentlicht 2002
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  19. 19
    A Membrane-targeted BID BCL-2 Homology 3 Peptide Is Sufficient for High Potency Activation of BAX in Vitro

    A Membrane-targeted BID BCL-2 Homology 3 Peptide Is Sufficient for High Potency Activation of BAX in Vitro von Kyoung Joon Oh, Scott Barbuto, Kenneth L. Pitter, Joel Morash, Loren D. Walensky, Stanley J. Korsmeyer

    Veröffentlicht 2006
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  20. 20
    Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies

    Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies von Gregory H. Bird, A. Irimia, Gilad Ofek, Peter D. Kwong, Ian A. Wilson, Loren D. Walensky

    Veröffentlicht 2014
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