نتائج البحث - Loaëc, Nadège

Synthesis of Thiazolo[5,4-f]quinazolin-9(8H)-ones as Multi-Target Directed Ligands of Ser/Thr Kinases حسب Hédou, Damien, Godeau, Julien, Loaëc, Nadège, Meijer, Laurent, Fruit, Corinne, Besson, Thierry

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Synthesis of Bioactive 2-(Arylamino)thiazolo[5,4-f]-quinazolin-9-ones via the Hügershoff Reaction or Cu- Catalyzed Intramolecular C-S Bond Formation حسب Hédou, Damien, Dubouilh-Benard, Carole, Loaëc, Nadège, Meijer, Laurent, Fruit, Corinne, Besson, Thierry

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Indole-3-Carbonitriles as DYRK1A Inhibitors by Fragment-Based Drug Design حسب Meine, Rosanna, Becker, Walter, Falke, Hannes, Preu, Lutz, Loaëc, Nadège, Meijer, Laurent, Kunick, Conrad

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Exploring Kinase Inhibition Properties of 9H-pyrimido[5,4-b]- and [4,5-b]indol-4-amine Derivatives حسب Loidreau, Yvonnick, Dubouilh-Benard, Carole, Nourrisson, Marie-Renée, Loaëc, Nadège, Meijer, Laurent, Besson, Thierry, Marchand, Pascal

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Molecular structures of cdc2-like kinases in complex with a new inhibitor chemotype حسب Walter, Anne, Chaikuad, Apirat, Helmer, Renate, Loaëc, Nadège, Preu, Lutz, Ott, Ingo, Knapp, Stefan, Meijer, Laurent, Kunick, Conrad

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[b]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors حسب Lechner, Christian, Flaßhoff, Maren, Falke, Hannes, Preu, Lutz, Loaëc, Nadége, Meijer, Laurent, Knapp, Stefan, Chaikuad, Apirat, Kunick, Conrad

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Novel Adociaquinone Derivatives from the Indonesian Sponge Xestospongia sp. حسب He, Fei, Mai, Linh H., Longeon, Arlette, Copp, Brent R., Loaëc, Nadège, Bescond, Amandine, Meijer, Laurent, Bourguet-Kondracki, Marie-Lise

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Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part I حسب Foucourt, Alicia, Hédou, Damien, Dubouilh-Benard, Carole, Désiré, Laurent, Casagrande, Anne-Sophie, Leblond, Bertrand, Loäec, Nadège, Meijer, Laurent, Besson, Thierry

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Sneaking Out for Happy Hour: Yeast-Based Approaches to Explore and Modulate Immune Response and Immune Evasion حسب Angrand, Gaëlle, Quillévéré, Alicia, Loaëc, Nadège, Daskalogianni, Chrysoula, Granzhan, Anton, Teulade-Fichou, Marie-Paule, Fahraeus, Robin, Prado Martins, Rodrigo, Blondel, Marc

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CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells حسب Bettayeb, Karima, Baunbæk, Dianne, Delehouze, Claire, Loaëc, Nadège, Hole, Alison J., Baumli, Sonja, Endicott, Jane A., Douc-Rasy, Setha, Bénard, Jean, Oumata, Nassima, Galons, Hervé, Meijer, Laurent

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10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A حسب Falke, Hannes, Chaikuad, Apirat, Becker, Anja, Loaëc, Nadège, Lozach, Olivier, Abu Jhaisha, Samira, Becker, Walter, Jones, Peter G., Preu, Lutz, Baumann, Knut, Knapp, Stefan, Meijer, Laurent, Kunick, Conrad

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Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis حسب Jarry, Marie, Lecointre, Céline, Malleval, Céline, Desrues, Laurence, Schouft, Marie-Thérèse, Lejoncour, Vadim, Liger, François, Lyvinec, Gildas, Joseph, Benoît, Loaëc, Nadège, Meijer, Laurent, Honnorat, Jérôme, Gandolfo, Pierrick, Castel, Hélène

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Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A حسب Nguyen, Thu Lan, Duchon, Arnaud, Manousopoulou, Antigoni, Loaëc, Nadège, Villiers, Benoît, Pani, Guillaume, Karatas, Meltem, Mechling, Anna E., Harsan, Laura-Adela, Limanton, Emmanuelle, Bazureau, Jean-Pierre, Carreaux, François, Garbis, Spiros D., Meijer, Laurent, Herault, Yann

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CDK/CK1 inhibitors roscovitine and CR8 down-regulate amplified MYCN in neuroblastoma cells حسب DELEHOUZE, Claire, GODL, Klaus, LOAEC, Nadège, BRUYERE, Céline, DESBAN, Nathalie, OUMATA, Nassima, GALONS, Hervé, ROUMELIOTIS, Theodoros I., GIANNOPOULOU, Eugenia G., GRENET, Jose, TWITCHELL, Devin, LAHTI, Jill, MOUCHET, Nicolas, GALIBERT, Marie-Dominique, GARBIS, Spiros D., MEIJER, Laurent

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A new mouse model of ARX dup24 recapitulates the patients’ behavioral and fine motor alterations حسب Dubos, Aline, Meziane, Hamid, Iacono, Giovanni, Curie, Aurore, Riet, Fabrice, Martin, Christelle, Loaëc, Nadège, Birling, Marie-Christine, Selloum, Mohammed, Normand, Elisabeth, Pavlovic, Guillaume, Sorg, Tania, Stunnenberg, Henk G, Chelly, Jamel, Humeau, Yann, Friocourt, Gaëlle, Hérault, Yann

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Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases حسب Loaëc, Nadège, Attanasio, Eletta, Villiers, Benoît, Durieu, Emilie, Tahtouh, Tania, Cam, Morgane, Davis, Rohan A., Alencar, Aline, Roué, Mélanie, Bourguet-Kondracki, Marie-Lise, Proksch, Peter, Limanton, Emmanuelle, Guiheneuf, Solène, Carreaux, François, Bazureau, Jean-Pierre, Klautau, Michelle, Meijer, Laurent

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Identification of 8-Hydroxyquinoline Derivatives That Decrease Cystathionine Beta Synthase (CBS) Activity حسب Conan, Pierre, Léon, Alice, Gourdel, Mathilde, Rollet, Claire, Chaïr, Loubna, Caroff, Noéline, Le Goux, Nelig, Le Jossic-Corcos, Catherine, Sinane, Maha, Gentile, Lucile, Maillebouis, Louise, Loaëc, Nadège, Martin, Jennifer, Vilaire, Marie, Corcos, Laurent, Mignen, Olivier, Croyal, Mikael, Voisset, Cécile, Bihel, Frédéric, Friocourt, Gaëlle

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Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis حسب Meijer, Laurent, Nelson, Deborah J., Riazanski, Vladimir, Gabdoulkhakova, Aida G., Hery-Arnaud, Geneviève, Le Berre, Rozenn, Loaëc, Nadège, Oumata, Nassima, Galons, Hervé, Nowak, Emmanuel, Gueganton, Laetitia, Dorothée, Guillaume, Prochazkova, Michaela, Hall, Bradford, Kulkarni, Ashok B., Gray, Robert D., Rossi, Adriano G., Witko-Sarsat, Véronique, Norez, Caroline, Becq, Frédéric, Ravel, Denis, Mottier, Dominique, Rault, Gilles

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