Resultats de la cerca - Loïc Yengo

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  1. 1
    Extreme inbreeding in a European ancestry sample from the contemporary UK population

    Extreme inbreeding in a European ancestry sample from the contemporary UK population per Loïc Yengo, Naomi R. Wray, Peter M. Visscher

    Publicat 2019
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  2. 2
    Heritable polygenic editing: the next frontier in genomic medicine?

    Heritable polygenic editing: the next frontier in genomic medicine? per Peter M. Visscher, Christopher Gyngell, Loïc Yengo, Julian Savulescu

    Publicat 2025
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  3. 3
    Discovery and implications of polygenicity of common diseases

    Discovery and implications of polygenicity of common diseases per Peter M. Visscher, Loïc Yengo, Nancy J. Cox, Naomi R. Wray

    Publicat 2021
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  4. 4
    15 years of GWAS discovery: Realizing the promise

    15 years of GWAS discovery: Realizing the promise per Abdel Abdellaoui, Loïc Yengo, Karin J. H. Verweij, Peter M. Visscher

    Publicat 2023
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  5. 5
    Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations

    Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations per Ying Wang, Jing Guo, Guiyan Ni, Jian Yang, Peter M. Visscher, Loïc Yengo

    Publicat 2020
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  6. 6
    Detection and quantification of inbreeding depression for complex traits from SNP data

    Detection and quantification of inbreeding depression for complex traits from SNP data per Loïc Yengo, Zhihong Zhu, Naomi R. Wray, Bruce S. Weir, Jian Yang, Matthew R. Robinson, Peter M. Visscher

    Publicat 2017
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  7. 7
    Early metabolic markers identify potential targets for the prevention of type 2 diabetes

    Early metabolic markers identify potential targets for the prevention of type 2 diabetes per Peddinti Gopalacharyulu, Jeff E. Cobb, Loïc Yengo, Philippe Froguel, Jasmina Kravić, Beverley Balkau, Jaakko Tuomilehto, Tero Aittokallio, Leif Groop

    Publicat 2017
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  8. 8
    Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

    Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals per Valentin Hivert, Julia Sidorenko, Florian Rohart, Michael E. Goddard, Jian Yang, Naomi R. Wray, Loïc Yengo, Peter M. Visscher

    Publicat 2021
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  9. 9
    The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis

    The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis per Amélie Bonnefond, Loïc Yengo, Cédric Le May, Frédéric Fumeron, Michel Marre, Beverley Balkau, Guillaume Charpentier, Sylvia Franc, Philippe Froguel, Bertrand Cariou

    Publicat 2015
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  10. 10
    Genome-wide association study of medication-use and associated disease in the UK Biobank

    Genome-wide association study of medication-use and associated disease in the UK Biobank per Yeda Wu, Enda M. Byrne, Zhili Zheng, Kathryn E. Kemper, Loïc Yengo, Andrew Mallett, Jian Yang, Peter M. Visscher, Naomi R. Wray

    Publicat 2019
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  11. 11
    Assortative mating biases marker-based heritability estimators

    Assortative mating biases marker-based heritability estimators per Richard Border, Sean O’Rourke, Teresa de Candia, Michael E. Goddard, Peter M. Visscher, Loïc Yengo, Matthew C. Jones, Matthew C. Keller

    Publicat 2022
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  12. 12
    Genetic influence on within-person longitudinal change in anthropometric traits in the UK Biobank

    Genetic influence on within-person longitudinal change in anthropometric traits in the UK Biobank per Kathryn E. Kemper, Julia Sidorenko, Huanwei Wang, Ben J. Hayes, Naomi R. Wray, Loïc Yengo, Matthew C. Keller, Michael E. Goddard, Peter M. Visscher

    Publicat 2024
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  13. 13
    Meta-analysis of genome-wide association studies for height and body mass index in ∼700,000 individuals of European ancestry

    Meta-analysis of genome-wide association studies for height and body mass index in ∼700,000 individuals of European ancestry per Loïc Yengo, Julia Sidorenko, Kathryn E. Kemper, Zhili Zheng, Andrew R. Wood, Michael N. Weedon, Timothy M. Frayling, Joel N. Hirschhorn, Jian Yang, Peter M. Visscher

    Publicat 2018
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  14. 14
    Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

    Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry per Loïc Yengo, Julia Sidorenko, Kathryn E. Kemper, Zhili Zheng, Andrew R. Wood, Michael N. Weedon, Timothy M. Frayling, Joel N. Hirschhorn, Jian Yang, Peter M. Visscher

    Publicat 2018
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  15. 15
    Detection of human adaptation during the past 2000 years

    Detection of human adaptation during the past 2000 years per Yair Field, Evan A. Boyle, Natalie Telis, Ziyue Gao, Kyle J. Gaulton, David E. Golan, Loïc Yengo, Ghislain Rocheleau, Philippe Froguel, Mark I. McCarthy, Jonathan K. Pritchard

    Publicat 2016
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  16. 16
    Beneficial effect of a high number of copies of salivary amylase AMY1 gene on obesity risk in Mexican children

    Beneficial effect of a high number of copies of salivary amylase AMY1 gene on obesity risk in Mexican children per María Aurora Mejía-Benitez, Amélie Bonnefond, Loïc Yengo, Marlène Huyvaert, Aurélie Dechaume, Jesús Peralta‐Romero, Miguel Klünder‐Klünder, Jaime García‐Mena, Julia S. El-Sayed Moustafa, Mario Falchi, Miguel Cruz, Philippe Froguel

    Publicat 2014
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  17. 17
    Widespread signatures of natural selection across human complex traits and functional genomic categories

    Widespread signatures of natural selection across human complex traits and functional genomic categories per Jian Zeng, Angli Xue, Longda Jiang, Luke R. Lloyd‐Jones, Yang Wu, Huanwei Wang, Zhili Zheng, Loïc Yengo, Kathryn E. Kemper, Michael E. Goddard, Naomi R. Wray, Peter M. Visscher, Jian Yang

    Publicat 2021
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  18. 18
    Imprint of assortative mating on the human genome

    Imprint of assortative mating on the human genome per Loïc Yengo, Matthew R. Robinson, Matthew C. Keller, Kathryn E. Kemper, Yuanhao Yang, Maciej Trzaskowski, Jacob Gratten, Patrick Turley, David Cesarini, Daniel J. Benjamin, Naomi R. Wray, Michael E. Goddard, Jian Yang, Peter M. Visscher

    Publicat 2018
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  19. 19
    Genetic correlates of social stratification in Great Britain

    Genetic correlates of social stratification in Great Britain per Abdel Abdellaoui, David Hugh-Jones, Loïc Yengo, Kathryn E. Kemper, Michel G. Nivard, Laura Veul, Yan Holtz, Brendan P. Zietsch, Timothy M. Frayling, Naomi R. Wray, Jian Yang, Karin J. H. Verweij, Peter M. Visscher

    Publicat 2019
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  20. 20
    Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization

    Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization per Gita A. Pathak, Kritika Singh, Tyne W. Miller‐Fleming, Frank R. Wendt, Nava Ehsan, Kangcheng Hou, Ruth Johnson, Zeyun Lu, Shyamalika Gopalan, Loïc Yengo, Pejman Mohammadi, Bogdan Paşaniuc, Renato Polimanti, Lea K. Davis, Nicholas Mancuso

    Publicat 2021
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