Søgeresultater - Liu, Lichuan

A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834 af Sodhi, Jasleen K., Wong, Susan, Kirkpatrick, Donald S., Liu, Lichuan, Khojasteh, S. Cyrus, Hop, Cornelis E. C. A., Barr, John T., Jones, Jeffrey P., Halladay, Jason S.

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Clinical responses to ERK inhibition in BRAF(V600E)-mutant colorectal cancer predicted using a computational model af Kirouac, Daniel C., Schaefer, Gabriele, Chan, Jocelyn, Merchant, Mark, Orr, Christine, Huang, Shih-Min A., Moffat, John, Liu, Lichuan, Gadkar, Kapil, Ramanujan, Saroja

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Erratum: Clinical responses to ERK inhibition in BRAF(V600E)-mutant colorectal cancer predicted using a computational model af Kirouac, Daniel C., Schaefer, Gabriele, Chan, Jocelyn, Merchant, Mark, Orr, Christine, Huang, Shih-Min A., Moffat, John, Liu, Lichuan, Gadkar, Kapil, Ramanujan, Saroja

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Application of a Novel ‘Make and Test in Parallel’ Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects af Cheeti, Sravanthi, Hou, Hao Helen, Nelson, Eric, Walker, Helen, Chen, Buyun, Morley, Roland, Gates, Mary, Musib, Luna, Girish, Sandhya, Sahasranaman, Srikumar, Liu, Lichuan

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Correction to: Application of a Novel ‘Make and Test in Parallel’ Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects af Cheeti, Sravanthi, Hou, Hao Helen, Nelson, Eric, Walker, Helen, Chen, Buyun, Morley, Roland, Gates, Mary, Musib, Luna, Girish, Sandhya, Sahasranaman, Srikumar, Liu, Lichuan

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Pharmacokinetics, Safety and Pharmacokinetics/Pharmacodynamics Analysis of Omadacycline in Chinese Healthy Subjects af Yang, Haijing, Huang, Zhiwei, Chen, Yuancheng, Zhu, Yusong, Cao, Guoying, Wang, Jingjing, Guo, Yan, Yu, Jicheng, Wu, Jufang, Liu, Lichuan, Deng, Jun, Liu, Jing, Reinhart, Harald, Zhang, Jing, Wu, Xiaojie

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SAHA Enhances Synaptic Function and Plasticity In Vitro but Has Limited Brain Availability In Vivo and Does Not Impact Cognition af Hanson, Jesse E., La, Hank, Plise, Emile, Chen, Yung-Hsiang, Ding, Xiao, Hanania, Taleen, Sabath, Emily V., Alexandrov, Vadim, Brunner, Dani, Leahy, Emer, Steiner, Pascal, Liu, Lichuan, Scearce-Levie, Kimberly, Zhou, Qiang

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Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically‐Based Pharmacokinetic Model af Chen, Yuan, Cabalu, Tamara D., Callegari, Ernesto, Einolf, Heidi, Liu, Lichuan, Parrott, Neil, Peters, Sheila Annie, Schuck, Edgar, Sharma, Pradeep, Tracey, Helen, Upreti, Vijay V., Zheng, Ming, Zhu, Andy Z.X., Hall, Stephen D.

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First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL af Byrd, John C., Smith, Stephen, Wagner-Johnston, Nina, Sharman, Jeff, Chen, Andy I., Advani, Ranjana, Augustson, Bradley, Marlton, Paula, Renee Commerford, S., Okrah, Kwame, Liu, Lichuan, Murray, Elaine, Penuel, Elicia, Ward, Ashley F., Flinn, Ian W.

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Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL af Byrd, John C., Smith, Stephen, Wagner-Johnston, Nina, Sharman, Jeff, Chen, Andy I., Advani, Ranjana, Augustson, Bradley, Marlton, Paula, Commerford, S. Renee, Okrah, Kwame, Liu, Lichuan, Murray, Elaine, Penuel, Elicia, Ward, Ashley F., Flinn, Ian W.

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Noncovalent inhibition of C481S Bruton tyrosine kinase by GDC-0853: a new treatment strategy for ibrutinib-resistant CLL af Reiff, Sean D., Muhowski, Elizabeth M., Guinn, Daphne, Lehman, Amy, Fabian, Catherine A., Cheney, Carolyn, Mantel, Rose, Smith, Lisa, Johnson, Amy J., Young, Wendy B., Johnson, Adam R., Liu, Lichuan, Byrd, John C., Woyach, Jennifer A.

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Stereochemical Differences in Fluorocyclopropyl Amides Enable Tuning of Btk Inhibition and Off-Target Activity af Crawford, James J., Lee, Wendy, Johnson, Adam R., Delatorre, Kelly J., Chen, Jacob, Eigenbrot, Charles, Heidmann, Julia, Kakiuchi-Kiyota, Satoko, Katewa, Arna, Kiefer, James R., Liu, Lichuan, Lubach, Joseph W., Misner, Dinah, Purkey, Hans, Reif, Karin, Vogt, Jennifer, Wong, Harvey, Yu, Christine, Young, Wendy B.

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Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349 af Pei, Zhonghua, Blackwood, Elizabeth, Liu, Lichuan, Malek, Shiva, Belvin, Marcia, Koehler, Michael F. T., Ortwine, Daniel F., Chen, Huifen, Cohen, Frederick, Kenny, Jane R., Bergeron, Philippe, Lau, Kevin, Ly, Cuong, Zhao, Xianrui, Estrada, Anthony A., Truong, Tom, Epler, Jennifer A., Nonomiya, Jim, Trinh, Lan, Sideris, Steve, Lesnick, John, Bao, Linda, Vijapurkar, Ulka, Mukadam, Sophie, Tay, Suzanne, Deshmukh, Gauri, Chen, Yung-Hsiang, Ding, Xiao, Friedman, Lori S., Lyssikatos, Joseph P.

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Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell–associated damage in IFNα-driven lupus nephritis af Katewa, Arna, Wang, Yugang, Hackney, Jason A., Huang, Tao, Suto, Eric, Ramamoorthi, Nandhini, Austin, Cary D., Bremer, Meire, Chen, Jacob Zhi, Crawford, James J., Currie, Kevin S., Blomgren, Peter, DeVoss, Jason, DiPaolo, Julie A., Hau, Jonathan, Johnson, Adam, Lesch, Justin, DeForge, Laura E., Lin, Zhonghua, Liimatta, Marya, Lubach, Joseph W., McVay, Sami, Modrusan, Zora, Nguyen, Allen, Poon, Chungkee, Wang, Jianyong, Liu, Lichuan, Lee, Wyne P., Wong, Harvey, Young, Wendy B., Townsend, Michael J., Reif, Karin

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Discovery of Potent and Selective Tricyclic Inhibitors of Bruton’s Tyrosine Kinase with Improved Druglike Properties af Wang, Xiaojing, Barbosa, James, Blomgren, Peter, Bremer, Meire C., Chen, Jacob, Crawford, James J., Deng, Wei, Dong, Liming, Eigenbrot, Charles, Gallion, Steve, Hau, Jonathon, Hu, Huiyong, Johnson, Adam R., Katewa, Arna, Kropf, Jeffrey E., Lee, Seung H., Liu, Lichuan, Lubach, Joseph W., Macaluso, Jen, Maciejewski, Pat, Mitchell, Scott A., Ortwine, Daniel F., DiPaolo, Julie, Reif, Karin, Scheerens, Heleen, Schmitt, Aaron, Wong, Harvey, Xiong, Jin-Ming, Xu, Jianjun, Zhao, Zhongdong, Zhou, Fusheng, Currie, Kevin S., Young, Wendy B.

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