Sökresultat - Lippert, Jörg

Physiologically Based Pharmacokinetic Modeling of Tamoxifen and its Metabolites in Women of Different CYP2D6 Phenotypes Provides New Insight into the Tamoxifen Mass Balance av Dickschen, Kristin, Willmann, Stefan, Thelen, Kirstin, Lippert, Jörg, Hempel, Georg, Eissing, Thomas

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Integrating Cellular Metabolism into a Multiscale Whole-Body Model av Krauss, Markus, Schaller, Stephan, Borchers, Steffen, Findeisen, Rolf, Lippert, Jörg, Kuepfer, Lars

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CKD subpopulations defined by risk‐factors: A longitudinal analysis of electronic health records av Ramaswamy, Rajagopalan, Wee, Soon Nan, George, Kavya, Ghosh, Abhijit, Sarkar, Joydeep, Burghaus, Rolf, Lippert, Jörg

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Quantitative systems pharmacology of interferon alpha administration: A multi-scale approach av Kalra, Priyata, Brandl, Julian, Gaub, Thomas, Niederalt, Christoph, Lippert, Jörg, Sahle, Sven, Küpfer, Lars, Kummer, Ursula

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Application of Physiologically‐Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin av Willmann, Stefan, Frei, Matthias, Sutter, Gabriele, Coboeken, Katrin, Wendl, Thomas, Eissing, Thomas, Lippert, Jörg, Stass, Heino

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Multiscale classification of heart failure phenotypes by unsupervised clustering of unstructured electronic medical record data av Nagamine, Tasha, Gillette, Brian, Pakhomov, Alexey, Kahoun, John, Mayer, Hannah, Burghaus, Rolf, Lippert, Jörg, Saxena, Mayur

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A generic framework for the physiologically‐based pharmacokinetic platform qualification of PK‐Sim and its application to predicting cytochrome P450 3A4–mediated drug–drug interact... av Frechen, Sebastian, Solodenko, Juri, Wendl, Thomas, Dallmann, André, Ince, Ibrahim, Lehr, Thorsten, Lippert, Jörg, Burghaus, Rolf

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A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim av Niederalt, Christoph, Kuepfer, Lars, Solodenko, Juri, Eissing, Thomas, Siegmund, Hans-Ulrich, Block, Michael, Willmann, Stefan, Lippert, Jörg

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Using Bayesian-PBPK modeling for assessment of inter-individual variability and subgroup stratification av Krauss, Markus, Burghaus, Rolf, Lippert, Jörg, Niemi, Mikko, Neuvonen, Pertti, Schuppert, Andreas, Willmann, Stefan, Kuepfer, Lars, Görlitz, Linus

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Development of a Paediatric Population-Based Model of the Pharmacokinetics of Rivaroxaban av Willmann, Stefan, Becker, Corina, Burghaus, Rolf, Coboeken, Katrin, Edginton, Andrea, Lippert, Jörg, Siegmund, Hans-Ulrich, Thelen, Kirstin, Mück, Wolfgang

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Population Pharmacokinetic and Exposure–Response Analysis of Finerenone: Insights Based on Phase IIb Data and Simulations to Support Dose Selection for Pivotal Trials in Type 2 Dia... av Snelder, Nelleke, Heinig, Roland, Drenth, Henk-Jan, Joseph, Amer, Kolkhof, Peter, Lippert, Jörg, Garmann, Dirk, Ploeger, Bart, Eissing, Thomas

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NT‐proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure av Schmitt, Walter, Rühs, Hauke, Burghaus, Rolf, Diedrich, Christian, Duwal, Sulav, Eissing, Thomas, Garmann, Dirk, Meyer, Michaela, Ploeger, Bart, Lippert, Jörg

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Computational investigation of potential dosing schedules for a switch of medication from warfarin to rivaroxaban—an oral, direct Factor Xa inhibitor av Burghaus, Rolf, Coboeken, Katrin, Gaub, Thomas, Niederalt, Christoph, Sensse, Anke, Siegmund, Hans-Ulrich, Weiss, Wolfgang, Mueck, Wolfgang, Tanigawa, Takahiko, Lippert, Jörg

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Establishing a Multidisciplinary Framework to Study Drug‐Drug Interactions of Hormonal Contraceptives: An Invitation to Collaborate av Lesko, Lawrence J., Vozmediano, Valvanera, Brown, Joshua D., Winterstein, Almut, Zhao, Ping, Lippert, Jörg, Höchel, Joachim, Chaturvedula, Ayyappa, White, Annesha, Schmidt, Stephan

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Pharmacokinetics of rivaroxaban in children using physiologically based and population pharmacokinetic modelling: an EINSTEIN-Jr phase I study av Willmann, Stefan, Thelen, Kirstin, Kubitza, Dagmar, Lensing, Anthonie W. A., Frede, Matthias, Coboeken, Katrin, Stampfuss, Jan, Burghaus, Rolf, Mück, Wolfgang, Lippert, Jörg

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Predictive Performance of Physiology‐Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small‐Molecule Compounds in Children av Ince, Ibrahim, Dallmann, André, Frechen, Sebastian, Coboeken, Katrin, Niederalt, Christoph, Wendl, Thomas, Block, Michael, Meyer, Michaela, Eissing, Thomas, Burghaus, Rolf, Lippert, Jörg, Willmann, Stefan, Schlender, Jan‐Frederik

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Data‐driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment av Fendt, Rebekka, Hofmann, Ute, Schneider, Annika R. P., Schaeffeler, Elke, Burghaus, Rolf, Yilmaz, Ali, Blank, Lars Mathias, Kerb, Reinhold, Lippert, Jörg, Schlender, Jan‐Frederik, Schwab, Matthias, Kuepfer, Lars

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Population pharmacokinetic analysis of rivaroxaban in children and comparison to prospective physiologically‐based pharmacokinetic predictions av Willmann, Stefan, Coboeken, Katrin, Zhang, Yang, Mayer, Hannah, Ince, Ibrahim, Mesic, Emir, Thelen, Kirstin, Kubitza, Dagmar, Lensing, Anthonie W. A., Yang, Haitao, Zhu, Peijuan, Mück, Wolfgang, Drenth, Henk‐Jan, Lippert, Jörg

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Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences av Lippert, Jörg, Burghaus, Rolf, Edginton, Andrea, Frechen, Sebastian, Karlsson, Mats, Kovar, Andreas, Lehr, Thorsten, Milligan, Peter, Nock, Valerie, Ramusovic, Sergej, Riggs, Matthew, Schaller, Stephan, Schlender, Jan, Schmidt, Stephan, Sevestre, Michaël, Sjögren, Erik, Solodenko, Juri, Staab, Alexander, Teutonico, Donato

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Smart Medical Information Technology for Healthcare (SMITH) : Data Integration based on Interoperability Standards av Winter, Alfred, Stäubert, Sebastian, Ammon, Danny, Aiche, Stephan, Beyan, Oya, Bischoff, Verena, Daumke, Philipp, Decker, Stefan, Funkat, Gert, Gewehr, Jan E., de Greiff, Armin, Haferkamp, Silke, Hahn, Udo, Henkel, Andreas, Kirsten, Toralf, Klöss, Thomas, Lippert, Jörg, Löbe, Matthias, Lowitsch, Volker, Maassen, Oliver, Maschmann, Jens, Meister, Sven, Mikolajczyk, Rafael, Nüchter, Matthias, Pletz, Mathias W., Rahm, Erhard, Riedel, Morris, Saleh, Kutaiba, Schuppert, Andreas, Smers, Stefan, Stollenwerk, André, Uhlig, Stefan, Wendt, Thomas, Zenker, Sven, Fleig, Wolfgang, Marx, Gernot, Scherag, André, Löffler, Markus

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