Rezultaty - Lin, Daniel C-H

GPR40 is Necessary but not Sufficient for Fatty-Acid Stimulation of Insulin Secretion in Vivo od Latour, Martin G., Alquier, Thierry, Oseid, Elizabeth, Tremblay, Caroline, Jetton, Thomas L., Luo, Jian, Lin, Daniel C.-H., Poitout, Vincent

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Structural basis for pharmacological modulation of the TRPC6 channel od Bai, Yonghong, Yu, Xinchao, Chen, Hao, Horne, Daniel, White, Ryan, Wu, Xiaosu, Lee, Paul, Gu, Yan, Ghimire-Rijal, Sudipa, Lin, Daniel C-H, Huang, Xin

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Discovery of AM-6226: A Potent and Orally Bioavailable GPR40 Full Agonist That Displays Efficacy in Nonhuman Primates od Brown, Sean P., Dransfield, Paul, Vimolratana, Marc, Zhu, Liusheng, Luo, Jian, Zhang, Jane, Jiao, XianYun, Pattaropong, Vatee, Wong, Simon, Zhuang, Run, Swaminath, Gayathri, Houze, Jonathan B., Lin, Daniel C.-H.

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Identification and Pharmacological Characterization of Multiple Allosteric Binding Sites on the Free Fatty Acid 1 Receptor od Lin, Daniel C.-H., Guo, Qi, Luo, Jian, Zhang, Jane, Nguyen, Kathy, Chen, Michael, Tran, Thanh, Dransfield, Paul J., Brown, Sean P., Houze, Jonathan, Vimolratana, Marc, Jiao, Xian Yun, Wang, Yingcai, Birdsall, Nigel J. M., Swaminath, Gayathri

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A Potent Class of GPR40 Full Agonists Engages the EnteroInsular Axis to Promote Glucose Control in Rodents od Luo, Jian, Swaminath, Gayathri, Brown, Sean P., Zhang, Jane, Guo, Qi, Chen, Michael, Nguyen, Kathy, Tran, Thanhvien, Miao, Lynn, Dransfield, Paul J., Vimolratana, Marc, Houze, Jonathan B., Wong, Simon, Toteva, Maria, Shan, Bei, Li, Frank, Zhuang, Run, Lin, Daniel C.-H.

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Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist od Brown, Sean P., Dransfield, Paul J., Vimolratana, Marc, Jiao, XianYun, Zhu, Liusheng, Pattaropong, Vatee, Sun, Ying, Liu, Jinqian, Luo, Jian, Zhang, Jane, Wong, Simon, Zhuang, Run, Guo, Qi, Li, Frank, Medina, Julio C., Swaminath, Gayathri, Lin, Daniel C.-H., Houze, Jonathan B.

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Optimization of GPR40 Agonists for Type 2 Diabetes od Liu, Jiwen (Jim), Wang, Yingcai, Ma, Zhihua, Schmitt, Mike, Zhu, Liusheng, Brown, Sean P., Dransfield, Paul J., Sun, Ying, Sharma, Rajiv, Guo, Qi, Zhuang, Run, Zhang, Jane, Luo, Jian, Tonn, George R., Wong, Simon, Swaminath, Gayathri, Medina, Julio C., Lin, Daniel C.-H., Houze, Jonathan B.

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AMG 837: A Novel GPR40/FFA1 Agonist that Enhances Insulin Secretion and Lowers Glucose Levels in Rodents od Lin, Daniel C.-H., Zhang, Jane, Zhuang, Run, Li, Frank, Nguyen, Kathy, Chen, Michael, Tran, Thanhvien, Lopez, Edwin, Lu, Jenny Ying Lin, Li, Xiaoyan Nina, Tang, Liang, Tonn, George R., Swaminath, Gayathri, Reagan, Jeff D., Chen, Jin-Long, Tian, Hui, Lin, Yi-Jyun, Houze, Jonathan B., Luo, Jian

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Aminopyrazole–Phenylalanine Based GPR142 Agonists: Discovery of Tool Compound and in Vivo Efficacy Studies od Yu, Ming, Lizarzaburu, Mike, Motani, Alykhan, Fu, Zice, Du, Xiaohui, Liu, Jiwen (Jim), Jiao, Xianyun, Lai, SuJen, Fan, Peter, Fu, Angela, Liu, Qingxiang, Murakoshi, Michiko, Nara, Futoshi, Oda, Kozo, Okuyama, Ryo, Reagan, Jeff D., Watanabe, Nobuaki, Yamazaki, Mami, Xiong, Yumei, Zhang, Ying, Zhuang, Run, Lin, Daniel C.-H., Houze, Jonathan B., Medina, Julio C., Li, Leping

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Improving the Pharmacokinetics of GPR40/FFA1 Full Agonists od Du, Xiaohui, Dransfield, Paul J., Lin, Daniel C.-H., Wong, Simon, Wang, Yingcai, Wang, Zhongyu, Kohn, Todd, Yu, Ming, Brown, Sean P., Vimolratana, Marc, Zhu, Liusheng, Li, An-Rong, Su, Yongli, Jiao, Xianyun, Liu, Jiwen (Jim), Swaminath, Gayathri, Tran, Thanhvien, Luo, Jian, Zhuang, Run, Zhang, Jane, Guo, Qi, Li, Frank, Connors, Richard, Medina, Julio C., Houze, Jonathan B.

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Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles od Wang, Yingcai, Liu, Jiwen (Jim), Dransfield, Paul J., Zhu, Liusheng, Wang, Zhongyu, Du, Xiaohui, Jiao, Xianyun, Su, Yongli, Li, An-rong, Brown, Sean P., Kasparian, Annie, Vimolratana, Marc, Yu, Ming, Pattaropong, Vatee, Houze, Jonathan B., Swaminath, Gayathri, Tran, Thanhvien, Nguyen, Khanh, Guo, Qi, Zhang, Jane, Zhuang, Run, Li, Frank, Miao, Lynn, Bartberger, Michael D., Correll, Tiffany L., Chow, David, Wong, Simon, Luo, Jian, Lin, Daniel C.-H., Medina, Julio C.

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