Canlyniadau Chwilio - Lin, Daniel C-H

GPR40 is Necessary but not Sufficient for Fatty-Acid Stimulation of Insulin Secretion in Vivo gan Latour, Martin G., Alquier, Thierry, Oseid, Elizabeth, Tremblay, Caroline, Jetton, Thomas L., Luo, Jian, Lin, Daniel C.-H., Poitout, Vincent

Cael y testun llawn Cael y testun llawn Cael y testun llawn

Structural basis for pharmacological modulation of the TRPC6 channel gan Bai, Yonghong, Yu, Xinchao, Chen, Hao, Horne, Daniel, White, Ryan, Wu, Xiaosu, Lee, Paul, Gu, Yan, Ghimire-Rijal, Sudipa, Lin, Daniel C-H, Huang, Xin

Cael y testun llawn Cael y testun llawn Cael y testun llawn

Discovery of AM-6226: A Potent and Orally Bioavailable GPR40 Full Agonist That Displays Efficacy in Nonhuman Primates gan Brown, Sean P., Dransfield, Paul, Vimolratana, Marc, Zhu, Liusheng, Luo, Jian, Zhang, Jane, Jiao, XianYun, Pattaropong, Vatee, Wong, Simon, Zhuang, Run, Swaminath, Gayathri, Houze, Jonathan B., Lin, Daniel C.-H.

Cael y testun llawn Cael y testun llawn Cael y testun llawn

Identification and Pharmacological Characterization of Multiple Allosteric Binding Sites on the Free Fatty Acid 1 Receptor gan Lin, Daniel C.-H., Guo, Qi, Luo, Jian, Zhang, Jane, Nguyen, Kathy, Chen, Michael, Tran, Thanh, Dransfield, Paul J., Brown, Sean P., Houze, Jonathan, Vimolratana, Marc, Jiao, Xian Yun, Wang, Yingcai, Birdsall, Nigel J. M., Swaminath, Gayathri

Cael y testun llawn Cael y testun llawn Cael y testun llawn

A Potent Class of GPR40 Full Agonists Engages the EnteroInsular Axis to Promote Glucose Control in Rodents gan Luo, Jian, Swaminath, Gayathri, Brown, Sean P., Zhang, Jane, Guo, Qi, Chen, Michael, Nguyen, Kathy, Tran, Thanhvien, Miao, Lynn, Dransfield, Paul J., Vimolratana, Marc, Houze, Jonathan B., Wong, Simon, Toteva, Maria, Shan, Bei, Li, Frank, Zhuang, Run, Lin, Daniel C.-H.

Cael y testun llawn Cael y testun llawn Cael y testun llawn

Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist gan Brown, Sean P., Dransfield, Paul J., Vimolratana, Marc, Jiao, XianYun, Zhu, Liusheng, Pattaropong, Vatee, Sun, Ying, Liu, Jinqian, Luo, Jian, Zhang, Jane, Wong, Simon, Zhuang, Run, Guo, Qi, Li, Frank, Medina, Julio C., Swaminath, Gayathri, Lin, Daniel C.-H., Houze, Jonathan B.

Cael y testun llawn Cael y testun llawn Cael y testun llawn

Optimization of GPR40 Agonists for Type 2 Diabetes gan Liu, Jiwen (Jim), Wang, Yingcai, Ma, Zhihua, Schmitt, Mike, Zhu, Liusheng, Brown, Sean P., Dransfield, Paul J., Sun, Ying, Sharma, Rajiv, Guo, Qi, Zhuang, Run, Zhang, Jane, Luo, Jian, Tonn, George R., Wong, Simon, Swaminath, Gayathri, Medina, Julio C., Lin, Daniel C.-H., Houze, Jonathan B.

Cael y testun llawn Cael y testun llawn Cael y testun llawn

AMG 837: A Novel GPR40/FFA1 Agonist that Enhances Insulin Secretion and Lowers Glucose Levels in Rodents gan Lin, Daniel C.-H., Zhang, Jane, Zhuang, Run, Li, Frank, Nguyen, Kathy, Chen, Michael, Tran, Thanhvien, Lopez, Edwin, Lu, Jenny Ying Lin, Li, Xiaoyan Nina, Tang, Liang, Tonn, George R., Swaminath, Gayathri, Reagan, Jeff D., Chen, Jin-Long, Tian, Hui, Lin, Yi-Jyun, Houze, Jonathan B., Luo, Jian

Cael y testun llawn Cael y testun llawn Cael y testun llawn

Aminopyrazole–Phenylalanine Based GPR142 Agonists: Discovery of Tool Compound and in Vivo Efficacy Studies gan Yu, Ming, Lizarzaburu, Mike, Motani, Alykhan, Fu, Zice, Du, Xiaohui, Liu, Jiwen (Jim), Jiao, Xianyun, Lai, SuJen, Fan, Peter, Fu, Angela, Liu, Qingxiang, Murakoshi, Michiko, Nara, Futoshi, Oda, Kozo, Okuyama, Ryo, Reagan, Jeff D., Watanabe, Nobuaki, Yamazaki, Mami, Xiong, Yumei, Zhang, Ying, Zhuang, Run, Lin, Daniel C.-H., Houze, Jonathan B., Medina, Julio C., Li, Leping

Cael y testun llawn Cael y testun llawn Cael y testun llawn

Improving the Pharmacokinetics of GPR40/FFA1 Full Agonists gan Du, Xiaohui, Dransfield, Paul J., Lin, Daniel C.-H., Wong, Simon, Wang, Yingcai, Wang, Zhongyu, Kohn, Todd, Yu, Ming, Brown, Sean P., Vimolratana, Marc, Zhu, Liusheng, Li, An-Rong, Su, Yongli, Jiao, Xianyun, Liu, Jiwen (Jim), Swaminath, Gayathri, Tran, Thanhvien, Luo, Jian, Zhuang, Run, Zhang, Jane, Guo, Qi, Li, Frank, Connors, Richard, Medina, Julio C., Houze, Jonathan B.

Cael y testun llawn Cael y testun llawn Cael y testun llawn

Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles gan Wang, Yingcai, Liu, Jiwen (Jim), Dransfield, Paul J., Zhu, Liusheng, Wang, Zhongyu, Du, Xiaohui, Jiao, Xianyun, Su, Yongli, Li, An-rong, Brown, Sean P., Kasparian, Annie, Vimolratana, Marc, Yu, Ming, Pattaropong, Vatee, Houze, Jonathan B., Swaminath, Gayathri, Tran, Thanhvien, Nguyen, Khanh, Guo, Qi, Zhang, Jane, Zhuang, Run, Li, Frank, Miao, Lynn, Bartberger, Michael D., Correll, Tiffany L., Chow, David, Wong, Simon, Luo, Jian, Lin, Daniel C.-H., Medina, Julio C.

Cael y testun llawn Cael y testun llawn Cael y testun llawn