Výsledky vyhledávání - Lijie Zhai

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  1. 1
    Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy

    Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy Autor Lijie Zhai, Stefani Spranger, David C. Binder, Galina Gritsina, Kristen L. Lauing, Francis J. Giles, Derek A. Wainwright

    Vydáno 2015
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  2. 2
    IDO1 in cancer: a Gemini of immune checkpoints

    IDO1 in cancer: a Gemini of immune checkpoints Autor Lijie Zhai, Erik Ladomersky, Alicia Lenzen, Brenda Nguyen, Ricky Patel, Kristen L. Lauing, Meijing Wu, Derek A. Wainwright

    Vydáno 2018
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  3. 3
    The role of IDO in brain tumor immunotherapy

    The role of IDO in brain tumor immunotherapy Autor Lijie Zhai, Kristen L. Lauing, Alan L. Chang, Mahua Dey, Jun Qian, Yu Cheng, Maciej S. Lesniak, Derek A. Wainwright

    Vydáno 2014
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  4. 4
    Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma

    Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma Autor Lijie Zhai, Erik Ladomersky, Carlos R. Dostal, Kristen L. Lauing, Kathleen Swoap, Leah K. Billingham, Galina Gritsina, Meijing Wu, Robert H. McCusker, David C. Binder, Derek A. Wainwright

    Vydáno 2017
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  5. 5
    The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma

    The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma Autor Erik Ladomersky, Denise Scholtens, Masha Kocherginsky, Elizabeth A. Hibler, Elizabeth T. Bartom, Sebastian Otto‐Meyer, Lijie Zhai, Kristen L. Lauing, Jaehyuk Choi, Jeffrey A. Sosman, Jennifer D. Wu, Bin Zhang, Rimas V. Lukas, Derek A. Wainwright

    Vydáno 2019
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  6. 6
    The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy

    The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy Autor Lijie Zhai, Mahua Dey, Kristen L. Lauing, Galina Gritsina, Rajwant Kaur, Rimas V. Lukas, M. Kelly Nicholas, Alfred Rademaker, Carlos R. Dostal, Robert H. McCusker, Jeffrey J. Raizer, Andrew T. Parsa, Orin Bloch, Derek A. Wainwright

    Vydáno 2015
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  7. 7
    Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival

    Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival Autor Lijie Zhai, Erik Ladomersky, Kristen L. Lauing, Meijing Wu, Matthew Genet, Galina Gritsina, Balázs Győrffy, Priscilla K. Brastianos, David C. Binder, Jeffrey A. Sosman, Francis J. Giles, C. David James, Craig Horbinski, Roger Stupp, Derek A. Wainwright

    Vydáno 2017
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  8. 8
    Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity

    Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity Autor Brittney R. Coats, Kelly Q. Schoenfelt, Valéria C. Barbosa-Lorenzi, Eduard Peris, Chang Cui, Alexandria Hoffman, Guolin Zhou, Sully Fernandez, Lijie Zhai, Ben A. Hall, Abigail S. Haka, Ajay M. Shah, Catherine A. Reardon, Matthew Brady, Christopher J. Rhodes, Frederick R. Maxfield, Lev Becker

    Vydáno 2017
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  9. 9
    Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies

    Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies Autor Lijie Zhai, April Bell, Erik Ladomersky, Kristen L. Lauing, Lakshmi Reddy Bollu, Jeffrey A. Sosman, Bin Zhang, Jennifer D. Wu, Stephen D. Miller, Joshua J. Meeks, Rimas V. Lukas, Eugene Wyatt, Lynn Doglio, Gary E. Schiltz, Robert H. McCusker, Derek A. Wainwright

    Vydáno 2020
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  10. 10
    IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma

    IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma Autor Erik Ladomersky, Lijie Zhai, Alicia Lenzen, Kristen L. Lauing, Jun Qian, Denise Scholtens, Galina Gritsina, Xuebing Sun, Ye Liu, Fenglong Yu, Wenfeng Gong, Yong Liu, Beibei Jiang, Tristin Tang, Ricky Patel, Leonidas C. Platanias, C. David James, Roger Stupp, Rimas V. Lukas, David C. Binder, Derek A. Wainwright

    Vydáno 2018
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  11. 11
    Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry

    Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry Autor Teresa T. Nguyen, Dong Ho Shin, Sagar Sohoni, Sanjay K. Singh, Yisel Rivera-Molina, Hong Jiang, Xuejun Fan, Joy Gumin, Frederick F. Lang, Christopher Alvarez‐Breckenridge, Filipa Godoy‐Vitorino, Lisha Zhu, W. Jim Zheng, Lijie Zhai, Erik Ladomersky, Kristen L. Lauing, Marta M. Alonso, Derek A. Wainwright, Candelaria Gómez-Manzano, Juàn Fueyo

    Vydáno 2022
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  12. 12
    Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma

    Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma Autor Lijie Zhai, April Bell, Erik Ladomersky, Kristen L. Lauing, Lakshmi Reddy Bollu, Brenda Nguyen, Matthew Genet, Miri Kim, Peiwen Chen, Xinlei Mi, Jennifer D. Wu, Matthew J. Schipma, Brian Wray, John R. Griffiths, Richard D. Unwin, Simon J. Clark, Rajesh Acharya, Riyue Bao, Craig Horbinski, Rimas V. Lukas, Gary E. Schiltz, Derek A. Wainwright

    Vydáno 2021
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  13. 13
    Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

    Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma Autor Erik Ladomersky, Lijie Zhai, Kristen L. Lauing, April Bell, Jiahui Xu, Masha Kocherginsky, Bin Zhang, Jennifer D. Wu, Joseph R. Podojil, Leonidas C. Platanias, Aaron Mochizuki, Robert M. Prins, Priya Kumthekar, Jeffrey J. Raizer, Karan Dixit, Rimas V. Lukas, Craig Horbinski, Wei Min, Changyou Zhou, Graham Pawelec, Judith Campisi, Ursula Grohmann, George C. Prendergast, David H. Munn, Derek A. Wainwright

    Vydáno 2020
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  14. 14
    Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma

    Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma Autor Lakshmi Reddy Bollu, Prashant V. Bommi, Paige J. Monsen, Lijie Zhai, Kristen L. Lauing, April Bell, Miri Kim, Erik Ladomersky, Xinyu Yang, Leonidas C. Platanias, Daniela Matei, Marcelo G. Bonini, Hidayatullah G. Munshi, Rintaro Hashizume, Jennifer D. Wu, Bin Zhang, C. David James, Peiwen Chen, Masha Kocherginsky, Craig Horbinski, Michael D. Cameron, Arabela A. Grigorescu, Bakhtiar Yamini, Rimas V. Lukas, Gary E. Schiltz, Derek A. Wainwright

    Vydáno 2022
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  15. 15
    Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)

    Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC) Autor Paige J. Monsen, Prashant V. Bommi, Arabela A. Grigorescu, Kristen L. Lauing, Yingyu Mao, P Berardi, Lijie Zhai, Ohiowele Ojo, Manon Penco-Campillo, Tad H. Koch, Michael Egozi, Sonam Jha, Sara F. Dunne, Hong Jiang, Guiqin Song, Zhang Fei, Steven Kregel, Ali Vaziri‐Gohar, Sean W. Fanning, Pilar Sánchez‐Gómez, Jacob M. Allen, Bakhtiar Yamini, Rimas V. Lukas, Derek A. Wainwright, Gary E. Schiltz

    Vydáno 2025
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  16. 16
    Glioblastoma as an age-related neurological disorder in adults

    Glioblastoma as an age-related neurological disorder in adults Autor Miri Kim, Erik Ladomersky, Andreas Mozny, Masha Kocherginsky, Kaitlyn O’Shea, Zachary Z. Reinstein, Lijie Zhai, April Bell, Kristen L. Lauing, Lakshmi Reddy Bollu, Erik E. Rabin, Karan Dixit, Priya Kumthekar, Leonidas C. Platanias, Lifang Hou, Yinan Zheng, Jennifer D. Wu, Bin Zhang, Maya Hrachova, Sarah Merrill, Maciej M. Mrugała, Vikram C. Prabhu, Craig Horbinski, C. David James, Bakhtiar Yamini, Quinn T. Ostrom, Margaret Johnson, David A. Reardon, Rimas V. Lukas, Derek A. Wainwright

    Vydáno 2021
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