Resultados de procura - Leroy Versteeg

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  1. 1
    Enlisting the mRNA Vaccine Platform to Combat Parasitic Infections

    Enlisting the mRNA Vaccine Platform to Combat Parasitic Infections por Leroy Versteeg, Mashal M. Almutairi, Peter J. Hotez, Jeroen Pollet

    Publicado 2019
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  2. 2
    A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection

    A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection por Meagan A. Barry, Leroy Versteeg, Qian Wang, Jeroen Pollet, Bin Zhan, Fabian Gusovsky, María Elena Bottazzi, Peter J. Hotez, Kathryn M. Jones

    Publicado 2019
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  3. 3
    Different responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models

    Different responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models por Ana Carolina Leão, María José Villar, Rakesh Adhikari, Cristina Poveda, Leroy Versteeg, Gregório Guilherme Almeida, Peter J. Hotez, María Elena Bottazzi, Kathryn M. Jones

    Publicado 2025
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  4. 4
    Vaccine-Linked Chemotherapy Improves Benznidazole Efficacy for Acute Chagas Disease

    Vaccine-Linked Chemotherapy Improves Benznidazole Efficacy for Acute Chagas Disease por Kathryn M. Jones, Leroy Versteeg, Ashish Damania, Brian Keegan, April Kendricks, Jeroen Pollet, Julio Vladimir Cruz-Chan, Fabian Gusovsky, Peter J. Hotez, María Elena Bottazzi

    Publicado 2018
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  5. 5
    Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection

    Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection por Leroy Versteeg, Junfei Wei, Zhuyun Liu, Brian Keegan, Ricardo Toshio Fujiwara, Kathryn M. Jones, Oluwatoyin A. Asojo, Ulrich Strych, María Elena Bottazzi, Peter J. Hotez, Bin Zhan

    Publicado 2020
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  6. 6
    Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates

    Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates por Andrey Carlos do Sacramento de Oliveira, Leroy Versteeg, Neima Briggs, Rakesh Adhikari, María José Villar, JeAnna R. Redd, Peter J. Hotez, María Elena Bottazzi, Jeroen Pollet

    Publicado 2025
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  7. 7
    Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease

    Vaccine-linked chemotherapy improves cardiac structure and function in a mouse model of chronic Chagas disease por Kathryn M. Jones, Elise N. Mangin, Corey L. Reynolds, Liliana E. Villanueva, Julio Vladimir Cruz, Leroy Versteeg, Brian Keegan, April Kendricks, Jeroen Pollet, Fabian Gusovsky, María Elena Bottazzi, Peter J. Hotez

    Publicado 2023
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  8. 8
    Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response

    Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response por Junfei Wei, Leroy Versteeg, Zhuyun Liu, Brian Keegan, Ana Clara Gazzinelli-Guimarães, Ricardo Toshio Fujiwara, Neima Briggs, Kathryn M. Jones, Ulrich Strych, Coreen M. Beaumier, María Elena Bottazzi, Peter J. Hotez, Bin Zhan

    Publicado 2017
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  9. 9
    <i>Ascaris</i> Larval Infection and Lung Invasion Directly Induce Severe Allergic Airway Disease in Mice

    <i>Ascaris</i> Larval Infection and Lung Invasion Directly Induce Severe Allergic Airway Disease in Mice por Jill E. Weatherhead, Paul Porter, Amy Coffey, Dana Haydel, Leroy Versteeg, Bin Zhan, Ana Clara Gazzinelli Guimarães, Ricardo Toshio Fujiwara, Ana M. Jaramillo, María Elena Bottazzi, Peter J. Hotez, David B. Corry, Coreen M. Beaumier

    Publicado 2018
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  10. 10
    Heterologous mRNA-protein vaccination with Tc24 induces a robust cellular immune response against Trypanosoma cruzi, characterized by an increased level of polyfunctional CD8+ T-cells

    Heterologous mRNA-protein vaccination with Tc24 induces a robust cellular immune response against Trypanosoma cruzi, characterized by an increased level of polyfunctional CD8+ T-ce... por Cristina Poveda, Ana Carolina Leão, Chiara Mancino, Francesca Taraballi, Yilin Chen, Rakesh Adhikari, María José Villar, Rakhi Kundu, Duc Nguyen, Leroy Versteeg, Ulrich Strych, Peter J. Hotez, María Elena Bottazzi, Jeroen Pollet, Kathryn M. Jones

    Publicado 2023
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  11. 11
    Harnessing RNA Technology to Advance Therapeutic Vaccine Antigens against Chagas Disease

    Harnessing RNA Technology to Advance Therapeutic Vaccine Antigens against Chagas Disease por Chiara Mancino, Jeroen Pollet, Assaf Zinger, Kathryn M. Jones, María José Villar, Ana Carolina Leão, Rakesh Adhikari, Leroy Versteeg, Rakhi Kundu, Ulrich Strych, Federica Giordano, Peter J. Hotez, María Elena Bottazzi, Francesca Taraballi, Cristina Poveda

    Publicado 2024
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  12. 12
    Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease

    Cysteine mutagenesis improves the production without abrogating antigenicity of a recombinant protein vaccine candidate for human chagas disease por Christopher A. Seid, Kathryn M. Jones, Jeroen Pollet, Brian Keegan, Elissa M. Hudspeth, Molly Hammond, Junfei Wei, C. Patrick McAtee, Leroy Versteeg, Amanda M. Gutierrez, Zhuyun Liu, Bin Zhan, Jonathan L. Respress, Ulrich Strych, María Elena Bottazzi, Peter J. Hotez

    Publicado 2016
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  13. 13
    Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate

    Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate por Wen‐Hsiang Chen, Junfei Wei, Rakhi Kundu, Rakesh Adhikari, Zhuyun Liu, Jungsoon Lee, Leroy Versteeg, Cristina Poveda, Brian Keegan, María José Villar, Ana Carolina de Araújo Leão, Joanne Altieri Rivera, Portia M. Gillespie, Jeroen Pollet, Ulrich Strych, Bin Zhan, Peter J. Hotez, María Elena Bottazzi

    Publicado 2021
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  14. 14
    Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate

    Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate por Wen‐Hsiang Chen, Jeroen Pollet, Ulrich Strych, Jungsoon Lee, Zhuyun Liu, Rakhi Kundu, Leroy Versteeg, María José Villar, Rakesh Adhikari, Junfei Wei, Cristina Poveda, Brian Keegan, Aaron O. Bailey, Yilin Chen, Portia M. Gillespie, Jason T. Kimata, Bin Zhan, Peter J. Hotez, María Elena Bottazzi

    Publicado 2021
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  15. 15
    SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice

    SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice por Jeroen Pollet, Wen‐Hsiang Chen, Leroy Versteeg, Brian Keegan, Bin Zhan, Junfei Wei, Zhuyun Liu, Jungsoon Lee, Rahki Kundu, Rakesh Adhikari, Cristina Poveda, María José Villar, Ana Carolina de Araújo Leão, Joanne Altieri Rivera, Zoha Momin, Portia M. Gillespie, Jason T. Kimata, Ulrich Strych, Peter J. Hotez, María Elena Bottazzi

    Publicado 2021
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  16. 16
    Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

    Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern por Jeroen Pollet, Ulrich Strych, Wen‐Hsiang Chen, Leroy Versteeg, Brian Keegan, Bin Zhan, Junfei Wei, Zhuyun Liu, Jungsoon Lee, Rahki Kundu, Rakesh Adhikari, Cristina Poveda, María José Villar, Syamala Rani Thimmiraju, Brianna Lopez, Portia M. Gillespie, Shannon E. Ronca, Jason T. Kimata, Martin Reers, Vikram Paradkar, Peter J. Hotez, María Elena Bottazzi

    Publicado 2022
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  17. 17
    DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M <sup>pro</sup> inhibitors

    DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M <sup>pro</sup> inhibitors por Srinivas Chamakuri, Shuo Lu, Melek N. Ucisik, Kurt M. Bohren, Ying‐Chu Chen, Huang-Chi Du, John C. Faver, Ravikumar Jimmidi, Feng Li, Jianyuan Li, Pranavanand Nyshadham, Stephen Palmer, Jeroen Pollet, Xuan Qin, Shannon E. Ronca, Banumathi Sankaran, Kiran Sharma, Zhi Tan, Leroy Versteeg, Zhifeng Yu, Martin M. Matzuk, Timothy Palzkill, Damian W. Young

    Publicado 2021
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  18. 18
    From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access

    From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access por Peter J. Hotez, Rakesh Adhikari, Wen‐Hsiang Chen, Yilin Chen, Portia M. Gillespie, Nelufa Islam, Brian Keegan, Rakhi Kundu, Jungsoon Lee, Zhuyun Liu, Jason T. Kimata, Numan Oezguen, Jeroen Pollet, Cristina Poveda, Kay Razavi, Shannon E. Ronca, Ulrich Strych, Syamala Rani Thimmiraju, Leroy Versteeg, Maria Jose Villar-Mondragon, Junfei Wei, Bin Zhan, María Elena Bottazzi

    Publicado 2023
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