Ngā hua rapu - Lelièvre, Jöel

Trioxaquines and Heme-Artemisinin Adducts Inhibit the In Vitro Formation of Hemozoin Better than Chloroquine mā Loup, Christophe, Lelièvre, Joël, Benoit-Vical, Françoise, Meunier, Bernard

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Activity of Clinically Relevant Antimalarial Drugs on Plasmodium falciparum Mature Gametocytes in an ATP Bioluminescence “Transmission Blocking” Assay mā Lelièvre, Joël, Almela, Maria Jesus, Lozano, Sonia, Miguel, Celia, Franco, Virginia, Leroy, Didier, Herreros, Esperanza

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Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence “transmission blocking” assay mā Lelièvre, Joël, Almela, Maria Jesus, Lozano, Sonia, Miguel, Celia, Franco, Virginia, Leroy, Didier, Herreros, Esperanza

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The antibiotic cyclomarin blocks arginine-phosphate–induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis mā Weinhäupl, Katharina, Brennich, Martha, Kazmaier, Uli, Lelievre, Joel, Ballell, Lluis, Goldberg, Alfred, Schanda, Paul, Fraga, Hugo

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Development of a whole‐cell high‐throughput phenotypic screen to identify inhibitors of mycobacterial amino acid biosynthesis mā Burke, Christopher, Abrahams, Katherine A., Richardson, Emily J., Loman, Nicholas J., Alemparte, Carlos, Lelievre, Joel, Besra, Gurdyal S.

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Use of a Locked-Nucleic-Acid Oligomer in the Clamped-Probe Assay for Detection of a Minority Pfcrt K76T Mutant Population of Plasmodium falciparum mā Senescau, Alice, Berry, Antoine, Benoit-Vical, Françoise, Landt, Olfert, Fabre, Richard, Lelièvre, Joël, Cassaing, Sophie, Magnaval, Jean-François

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Increased Tolerance to Artemisinin in Plasmodium falciparum Is Mediated by a Quiescence Mechanism mā Witkowski, Benoit, Lelièvre, Joel, López Barragán, María José, Laurent, Victor, Su, Xin-zhuan, Berry, Antoine, Benoit-Vical, Françoise

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A New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug Discovery mā Almela, Maria Jesus, Lozano, Sonia, Lelièvre, Joël, Colmenarejo, Gonzalo, Coterón, José Miguel, Rodrigues, Janneth, Gonzalez, Carolina, Herreros, Esperanza

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Male and Female Plasmodium falciparum Mature Gametocytes Show Different Responses to Antimalarial Drugs mā Delves, Michael J., Ruecker, Andrea, Straschil, Ursula, Lelièvre, Jöel, Marques, Sara, López-Barragán, María José, Herreros, Esperanza, Sinden, Robert E.

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Development of high throughput screening methods for inhibitors of ClpC1P1P2 from Mycobacteria tuberculosis mā Fraga, Hugo, Rodriguez, Beatriz, Bardera, Ana, Cid, Concha, Akopian, Tatos, Kandror, Olga, Park, Annie, Colmenarejo, Gonzalo, Lelievre, Joel, Goldberg, Alfred

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Lack of Specificity of Phenotypic Screens for Inhibitors of the Mycobacterium tuberculosis FAS-II System mā Grzegorzewicz, Anna E., Lelièvre, Joël, Esquivias, Jorge, Angala, Bhanupriya, Liu, Jiuyu, Lee, Richard E., McNeil, Michael R., Jackson, Mary

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Collaborative approaches for Target ID in neglected diseases: identifying new antimalarial targets mā Lafuente, Maria Jose, Guidelli-Disse, Sonja, Selenski, Carolyn, Lelievre, Joel, Willson, Timothy, Gamo, Francisco Javier, Drewes, Gerard, Vandal, Omar, Ballell-Pages, Luis

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A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents mā Bahamontes-Rosa, Noemí, Gomez-Lorenzo, María G., Lelièvre, Joël, Rodriguez Alejandre, Ane, Almela, María Jesus, Lozano, Sonia, Herreros, Esperanza, Gamo, Francisco-Javier

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Trioxaquines Are New Antimalarial Agents Active on All Erythrocytic Forms, Including Gametocytes mā Benoit-Vical, Françoise, Lelièvre, Joël, Berry, Antoine, Deymier, Caroline, Dechy-Cabaret, Odile, Cazelles, Jérôme, Loup, Christophe, Robert, Anne, Magnaval, Jean-François, Meunier, Bernard

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Evidence for the Contribution of the Hemozoin Synthesis Pathway of the Murine Plasmodium yoelii to the Resistance to Artemisinin-Related Drugs mā Witkowski, Benoit, Lelièvre, Joel, Nicolau-Travers, Marie-Laure, Iriart, Xavier, Njomnang Soh, Patrice, Bousejra-ElGarah, Fatima, Meunier, Bernard, Berry, Antoine, Benoit-Vical, Françoise

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Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach mā Mugumbate, Grace, Mendes, Vitor, Blaszczyk, Michal, Sabbah, Mohamad, Papadatos, George, Lelievre, Joel, Ballell, Lluis, Barros, David, Abell, Chris, Blundell, Tom L., Overington, John P.

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Development of a novel secondary phenotypic screen to identify hits within the mycobacterial protein synthesis pipeline mā Burke, Christopher, Jankute, Monika, Moynihan, Patrick, Gonzalez del Rio, Ruben, Li, Xiaojun, Esquivias, Jorge, Lelièvre, Joël, Cox, Jonathan A. G., Sacchettini, James, Besra, Gurdyal S.

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A Leucyl-tRNA Synthetase Inhibitor with Broad-Spectrum Antimycobacterial Activity mā Ganapathy, Uday S., González del Rio, Rubén, Cacho-Izquierdo, Mónica, Ortega, Fátima, Lelièvre, Joël, Barros-Aguirre, David, Lindman, Marissa, Dartois, Véronique, Gengenbacher, Martin, Dick, Thomas

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The multi-target aspect of an MmpL3 inhibitor: The BM212 series of compounds bind EthR2, a transcriptional regulator of ethionamide activation mā Moorey, Alice R., Cabanillas, Alejandro, Batt, Sarah M., Ghidelli-Disse, Sonja, Urones, Beatriz, Sanz, Olalla, Lelievre, Joel, Bantscheff, Marcus, Cox, Liam R., Besra, Gurdyal S.

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Red blood cells derived from peripheral blood and bone marrow CD34+ human haematopoietic stem cells are permissive to Plasmodium parasites infection mā Fernandez-Becerra, Carmen, Lelievre, Joel, Ferrer, Mireia, Anton, Nuria, Thomson, Richard, Peligero, Cristina, Almela, Maria Jesus, Lacerda, Marcus VG, Herreros, Esperanza, del Portillo, Hernando A

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