Search Results - Leiserson, Mark D. M.

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  1. 1
    Modeling clinical and molecular covariates of mutational process activity in cancer

    Modeling clinical and molecular covariates of mutational process activity in cancer by Robinson, Welles, Sharan, Roded, Leiserson, Mark D M

    Published 2019
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  2. 2
    A data-driven approach for constructing mutation categories for mutational signature analysis

    A data-driven approach for constructing mutation categories for mutational signature analysis by Gilad, Gal, Leiserson, Mark D. M., Sharan, Roded

    Published 2021
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  3. 3
    A weighted exact test for mutually exclusive mutations in cancer

    A weighted exact test for mutually exclusive mutations in cancer by Leiserson, Mark D.M., Reyna, Matthew A., Raphael, Benjamin J.

    Published 2016
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  4. 4
    Hierarchical HotNet: identifying hierarchies of altered subnetworks

    Hierarchical HotNet: identifying hierarchies of altered subnetworks by Reyna, Matthew A, Leiserson, Mark D M, Raphael, Benjamin J

    Published 2018
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  5. 5
    A mixture model for signature discovery from sparse mutation data

    A mixture model for signature discovery from sparse mutation data by Sason, Itay, Chen, Yuexi, Leiserson, Mark D.M., Sharan, Roded

    Published 2021
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  6. 6
    ScalpelSig Designs Targeted Genomic Panels from Data to Detect Activity of Mutational Signatures

    ScalpelSig Designs Targeted Genomic Panels from Data to Detect Activity of Mutational Signatures by Franzese, Nicholas, Fan, Jason, Sharan, Roded, Leiserson, Mark D.M.

    Published 2022
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  7. 7
    Simultaneous Identification of Multiple Driver Pathways in Cancer

    Simultaneous Identification of Multiple Driver Pathways in Cancer by Leiserson, Mark D. M., Blokh, Dima, Sharan, Roded, Raphael, Benjamin J.

    Published 2013
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  8. 8
    Precision Oncology: The Road Ahead

    Precision Oncology: The Road Ahead by Senft, Daniela, Leiserson, Mark D M, Ruppin, Eytan, Ronai, Zéev A

    Published 2017
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  9. 9
    DNA REPAIR FOOTPRINT UNCOVERS CONTRIBUTION OF DNA REPAIR MECHANISM TO MUTATIONAL SIGNATURES

    DNA REPAIR FOOTPRINT UNCOVERS CONTRIBUTION OF DNA REPAIR MECHANISM TO MUTATIONAL SIGNATURES by Wojtowicz, Damian, Leiserson, Mark D.M., Sharan, Roded, Przytycka, Teresa M.

    Published 2020
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  10. 10
    Inferring Mechanisms of Compensation from E-MAP and SGA Data Using Local Search Algorithms for Max Cut

    Inferring Mechanisms of Compensation from E-MAP and SGA Data Using Local Search Algorithms for Max Cut by Leiserson, Mark D.M., Tatar, Diana, Cowen, Lenore J., Hescott, Benjamin J.

    Published 2011
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  11. 11
    Erratum to: CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer

    Erratum to: CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer by Leiserson, Mark D. M., Wu, Hsin-Ta, Vandin, Fabio, Raphael, Benjamin J.

    Published 2016
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  12. 12
    SuperDendrix algorithm integrates genetic dependencies and genomic alterations across pathways and cancer types

    SuperDendrix algorithm integrates genetic dependencies and genomic alterations across pathways and cancer types by Park, Tae Yoon, Leiserson, Mark D.M., Klau, Gunnar W., Raphael, Benjamin J.

    Published 2022
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  13. 13
    Criticality in tumor evolution and clinical outcome

    Criticality in tumor evolution and clinical outcome by Persi, Erez, Wolf, Yuri I., Leiserson, Mark D. M., Koonin, Eugene V., Ruppin, Eytan

    Published 2018
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  14. 14
    A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer

    A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer by Sason, Itay, Wojtowicz, Damian, Robinson, Welles, Leiserson, Mark D.M., Przytycka, Teresa M., Sharan, Roded

    Published 2020
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  15. 15
    Functional protein representations from biological networks enable diverse cross-species inference

    Functional protein representations from biological networks enable diverse cross-species inference by Fan, Jason, Cannistra, Anthony, Fried, Inbar, Lim, Tim, Schaffner, Thomas, Crovella, Mark, Hescott, Benjamin, Leiserson, Mark D M

    Published 2019
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  16. 16
    Hidden Markov models lead to higher resolution maps of mutation signature activity in cancer

    Hidden Markov models lead to higher resolution maps of mutation signature activity in cancer by Wojtowicz, Damian, Sason, Itay, Huang, Xiaoqing, Kim, Yoo-Ah, Leiserson, Mark D. M., Przytycka, Teresa M., Sharan, Roded

    Published 2019
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  17. 17
    Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer

    Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer by Kim, Yoo-Ah, Wojtowicz, Damian, Sarto Basso, Rebecca, Sason, Itay, Robinson, Welles, Hochbaum, Dorit S., Leiserson, Mark D. M., Sharan, Roded, Vadin, Fabio, Przytycka, Teresa M.

    Published 2020
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  18. 18
    A multifactorial model of T cell expansion and durable clinical benefit in response to a PD-L1 inhibitor

    A multifactorial model of T cell expansion and durable clinical benefit in response to a PD-L1 inhibitor by Leiserson, Mark D. M., Syrgkanis, Vasilis, Gilson, Amy, Dudik, Miroslav, Gillett, Sharon, Chayes, Jennifer, Borgs, Christian, Bajorin, Dean F., Rosenberg, Jonathan E., Funt, Samuel, Snyder, Alexandra, Mackey, Lester

    Published 2018
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  19. 19
    A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing

    A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing by Sinha, Sanju, Barbosa, Karina, Cheng, Kuoyuan, Leiserson, Mark D. M., Jain, Prashant, Deshpande, Anagha, Wilson, David M., Ryan, Bríd M., Luo, Ji, Ronai, Ze’ev A., Lee, Joo Sang, Deshpande, Aniruddha J., Ruppin, Eytan

    Published 2021
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  20. 20
    Author Correction: A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing

    Author Correction: A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing by Sinha, Sanju, Barbosa, Karina, Cheng, Kuoyuan, Leiserson, Mark D. M., Jain, Prashant, Deshpande, Anagha, Wilson, David M., Ryan, Bríd M., Luo, Ji, Ronai, Ze’ev A., Lee, Joo Sang, Deshpande, Aniruddha J., Ruppin, Eytan

    Published 2022
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