検索結果 - Leila Gobejishvili

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  1. 1
    Role of cAMP and phosphodiesterase signaling in liver health and disease

    Role of cAMP and phosphodiesterase signaling in liver health and disease 著者: Banrida Wahlang, Craig J. McClain, Shirish Barve, Leila Gobejishvili

    出版事項 2018
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  2. 2
    Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease

    Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease 著者: Leila Gobejishvili, Shirish Barve, Swati Joshi‐Barve, Craig J. McClain

    出版事項 2008
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  3. 3
    Dysregulation of hepatic <scp>cAMP</scp> levels via altered Pde4b expression plays a critical role in alcohol‐induced steatosis

    Dysregulation of hepatic <scp>cAMP</scp> levels via altered Pde4b expression plays a critical role in alcohol‐induced steatosis 著者: Diana Avila, David F. Barker, Jingwen Zhang, Craig J. McClain, Shirish Barve, Leila Gobejishvili

    出版事項 2016
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  4. 4
    Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes

    Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes 著者: Swati Joshi‐Barve, Shirish Barve, Kiranmayi Amancherla, Leila Gobejishvili, Daniell B. Hill, Matthew C. Cave, Prachi Hote, Craig J. McClain

    出版事項 2007
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    Artigo
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  5. 5
    Binge Alcohol–Induced Microvesicular Liver Steatosis and Injury are Associated with Down‐Regulation of Hepatic <scp><i>Hdac</i></scp><i>1, 7, 9, 10, 11</i> and Up‐Regulation of <scp><i>Hdac</i></scp><i>3</i>

    Binge Alcohol–Induced Microvesicular Liver Steatosis and Injury are Associated with Down‐Regulation of Hepatic <scp><i>Hdac</i></scp><i>1, 7, 9, 10, 11</i> and Up‐Regulation of <sc... 著者: Irina Kirpich, Smita Ghare, Jingwen Zhang, Leila Gobejishvili, Giorgi Kharebava, Swati Barve, David Barker, Akshata Moghe, Craig J. McClain, Shirish Barve

    出版事項 2012
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  6. 6
    Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease

    Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease 著者: Irina Kirpich, Leila Gobejishvili, Marjorie Bon Homme, Sabine Waigel, Matt Cave, Gavin E. Arteel, Shirish Barve, Craig J. McClain, Ion V. Deaciuc

    出版事項 2010
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  7. 7
    Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation

    Phosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammation 著者: Diana Avila, Scott A. Myers, Jingwen Zhang, Giorgi Kharebava, Craig J. McClain, Hee‐Yong Kim, Scott R. Whittemore, Leila Gobejishvili, Shirish Barve

    出版事項 2017
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  8. 8
    Tributyrin Inhibits Ethanol-Induced Epigenetic Repression of CPT-1A and Attenuates Hepatic Steatosis and Injury

    Tributyrin Inhibits Ethanol-Induced Epigenetic Repression of CPT-1A and Attenuates Hepatic Steatosis and Injury 著者: Hridgandh Donde, Smita Ghare, Swati Joshi‐Barve, Jingwen Zhang, Manicka V. Vadhanam, Leila Gobejishvili, Pawel Lorkiewicz, Sanjay Srivastava, Craig J. McClain, Shirish Barve

    出版事項 2019
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  9. 9
    Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia

    Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia 著者: Scott A. Myers, Leila Gobejishvili, Sujata Saraswat Ohri, C. Garrett Wilson, Kariena R. Andres, Amberly S. Riegler, Hridgandh Donde, Swati Joshi‐Barve, Shirish Barve, Scott R. Whittemore

    出版事項 2018
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    Artigo
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  10. 10
    Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells

    Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells 著者: Dominique Jones, Marianne Schmidt, Suman Suman, Katharine R. Hobbing, Shirish Barve, Leila Gobejishvili, Guy Brock, Carolyn M. Klinge, N. Shesh, Jong Kook Park, Geoffrey Clark, Rajesh Agarwal, LaCreis R. Kidd

    出版事項 2018
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    Artigo
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  11. 11
    Metagenomic Analyses of Alcohol Induced Pathogenic Alterations in the Intestinal Microbiome and the Effect of Lactobacillus rhamnosus GG Treatment

    Metagenomic Analyses of Alcohol Induced Pathogenic Alterations in the Intestinal Microbiome and the Effect of Lactobacillus rhamnosus GG Treatment 著者: Lara Bull–Otterson, Wenke Feng, Irina Kirpich, Yuhua Wang, Xiang Qin, Yanlong Liu, Leila Gobejishvili, Swati Joshi‐Barve, Tulin Ayvaz, Joseph F. Petrosino, Maiying Kong, David Barker, Craig J. McClain, Shirish Barve

    出版事項 2013
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  12. 12
    Keratin 18 Is a Diagnostic and Prognostic Factor for Acute Alcoholic Hepatitis

    Keratin 18 Is a Diagnostic and Prognostic Factor for Acute Alcoholic Hepatitis 著者: Vatsalya Vatsalya, Matthew C. Cave, Maiying Kong, Leila Gobejishvili, K. Cameron Falkner, John Craycroft, Mack C. Mitchell, Gyöngyi Szabó, Arthur J. McCullough, Srinivasan Dasarathy, Svetlana Radaeva, Bruce Barton, Craig J. McClain

    出版事項 2019
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  13. 13
    Phosphodiesterase 4 Inhibition as a Therapeutic Target for Alcoholic Liver Disease: From Bedside to Bench

    Phosphodiesterase 4 Inhibition as a Therapeutic Target for Alcoholic Liver Disease: From Bedside to Bench 著者: Walter Rodríguez, Banrida Wahlang, Yali Wang, Jingwen Zhang, Manicka V. Vadhanam, Swati Joshi‐Barve, Philip M. Bauer, Robert M. Cannon, Ali Reza Ahmadi, Zhaoli Sun, Andrew Cameron, Shirish Barve, Claudio Maldonado, Craig J. McClain, Leila Gobejishvili

    出版事項 2019
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  14. 14
    Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver disease in mice

    Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver dise... 著者: Richa Singhal, Hridgandh Donde, Smita Ghare, Kendall S. Stocke, Jingwein Zhang, Manicka V. Vadhanam, Sreelatha Reddy, Leila Gobejishvili, Paula M. Chilton, Swati Joshi‐Barve, Wenke Feng, Craig J. McClain, Kristi L. Hoffman, Joseph F. Petrosino, Marius Vital, Shirish Barve

    出版事項 2021
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  15. 15
    Age-associated temporal decline in butyrate-producing bacteria plays a key pathogenic role in the onset and progression of neuropathology and memory deficits in 3×Tg-AD mice

    Age-associated temporal decline in butyrate-producing bacteria plays a key pathogenic role in the onset and progression of neuropathology and memory deficits in 3×Tg-AD mice 著者: Paula M. Chilton, Smita Ghare, B Charpentier, S Myers, Aakarsha V. Rao, Joseph F. Petrosino, Kristi L. Hoffman, John C. Greenwell, Neetu Tyagi, Jyotirmaya Behera, Yali Wang, Lucy Sloan, JingWen Zhang, Christopher Shields, Gregory E. Cooper, Leila Gobejishvili, Scott R. Whittemore, Craig J. McClain, Shirish Barve

    出版事項 2024
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  16. 16
    Cyclic nucleotide phosphodiesterases as drug targets

    Cyclic nucleotide phosphodiesterases as drug targets 著者: Michy P. Kelly, Viacheslav O. Nikolaev, Leila Gobejishvili, Claire Lugnier, Christian Heßlinger, Peter Nickolaus, David A. Kass, W. Pereira De Vasconcelos, Rodolphe Fischmeister, Stefan Brocke, Paul M. Epstein, Gary A. Piazza, Adam B. Keeton, Gang Zhou, Mohammad Abdel‐Halim, Alireza Abadi, George S. Baillie, Mark A. Giembycz, Graeme B. Bolger, Gretchen L. Snyder, Kjetil Taskén, Nathaniel Edward Bennett Saidu, Martina Schmidt, Manuela Zaccolo, Ralph T. Schermuly, Hengming Ke, Rick Cote, Soroush Mohammadi Jouabadi, Anton J.M. Roks

    出版事項 2025
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